Search filters

List of works by Mary E. Abood

(-)-7'-Isothiocyanato-11-hydroxy-1',1'-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six and activates the CB1 cannabinoid receptor

scientific article

3-(1',1'-Dimethylbutyl)-1-deoxy-delta8-THC and related compounds: synthesis of selective ligands for the CB2 receptor

scientific article

A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition

scientific article

AM1241, a cannabinoid CB2 receptor selective compound, delays disease progression in a mouse model of amyotrophic lateral sclerosis

scientific article

Activation of GPR18 by cannabinoid compounds: a tale of biased agonism.

scientific article

Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity

scientific article published in August 2001

Allosteric Modulators: A Side Door

scientific article published on 08 December 2015

Allosteric modulation of a cannabinoid G protein-coupled receptor: binding site elucidation and relationship to G protein signaling

scientific article published on 23 December 2013

Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity.

scientific article published on February 2008

Amyotrophic lateral sclerosis: delayed disease progression in mice by treatment with a cannabinoid

scientific article

An Aromatic Microdomain at the Cannabinoid CB1 Receptor Constitutes an Agonist/Inverse Agonist Binding Region

scientific article published on November 20, 2003

Analysis of the antinociceptive actions of the kappa-opioid agonist enadoline (CI-977) in neonatal and adult rats: comparison to kappa-opioid receptor mRNA ontogeny

scientific article published in June 1995

Antinociceptive activity of chemical congeners of improgan: optimization of side chain length leads to the discovery of a new, potent, non-opioid analgesic

scientific article published on 23 June 2006

Antisense oligodeoxynucleotides to the kappa-1 receptor block the antinociceptive effects of delta 9-THC in the spinal cord

scientific article published in August 1995

Application of Fluorine- and Nitrogen-Walk Approaches: Defining the Structural and Functional Diversity of 2-Phenylindole Class of Cannabinoid 1 Receptor Positive Allosteric Modulators

scientific article published on 03 January 2020

Atypical responsiveness of the orphan receptor GPR55 to cannabinoid ligands

scientific article

Biarylpyrazole inverse agonists at the cannabinoid CB1 receptor: importance of the C-3 carboxamide oxygen/lysine3.28(192) interaction.

scientific article

CB(1) receptor allosteric modulators display both agonist and signaling pathway specificity.

scientific article published on 15 November 2012

CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury.

scientific article published on 28 March 2009

CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides

scientific article

Cannabinoid receptor activation reduces TNFalpha-induced surface localization of AMPAR-type glutamate receptors and excitotoxicity.

scientific article

Cannabinoid receptor down-regulation without alteration of the inhibitory effect of CP 55,940 on adenylyl cyclase in the cerebellum of CP 55,940-tolerant mice

scientific article published in January 1996

Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Cannabinoid receptors in developing rats: detection of mRNA and receptor binding

scientific article published in August 1994

Cannabinoid receptors: nomenclature and pharmacological principles

scientific article

Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells

scientific article published in August 2005

Cannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials.

scientific article published on 3 May 2010

Cocaine inhibits store-operated Ca2+ entry in brain microvascular endothelial cells: critical role for sigma-1 receptors

scientific article published on 14 October 2015

Crucial positively charged residues for ligand activation of the GPR35 receptor

scientific article published on 17 December 2013

Development of behavioral tolerance to delta 9-THC without alteration of cannabinoid receptor binding or mRNA levels in whole brain

scientific article published in November 1993

Developmental expression of cannabinoid receptor mRNA.

scientific article published in November 1993

Differential activation of cultured neonatal cardiomyocytes by plasmalemmal versus intracellular G protein-coupled receptor 55.

scientific article published on 27 June 2013

Differential activation of intracellular versus plasmalemmal CB2 cannabinoid receptors.

scientific article

Expression of a cannabinoid receptor in baculovirus-infected insect cells.

scientific article published on September 1994

Functional interaction between HIV-gp120 and opioid system in the preoptic anterior hypothalamus

scientific article published on 26 September 2013

G protein-coupled estrogen receptor-mediated effects on cytosolic calcium and nanomechanics in brain microvascular endothelial cells.

scientific article

HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions.

scientific article

HIV-gp120 and physical dependence to buprenorphine

scientific article

Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms

scientific article published on 26 June 2007

High-level expression of the human CB2 cannabinoid receptor using a baculovirus system.

scientific article published on June 1998

Identification of Crucial Amino Acid Residues Involved in Agonist Signaling at the GPR55 Receptor

scientific article published on 22 December 2016

Identification of the GPR55 antagonist binding site using a novel set of high-potency GPR55 selective ligands.

scientific article

Importance of the C-1 Substituent in Classical Cannabinoids to CB2Receptor Selectivity: Synthesis and Characterization of a Series ofO,2-Propano-Δ8-tetrahydrocannabinol Analogs

scientific article published on 01 September 1997

Intracellular cannabinoid type 1 (CB1) receptors are activated by anandamide

scientific article

Isolation and developmental expression of a rat cDNA encoding a cysteine-rich zinc finger protein

scientific journal article

Isolation and expression of a mouse CB1 cannabinoid receptor gene. Comparison of binding properties with those of native CB1 receptors in mouse brain and N18TG2 neuroblastoma cells.

scientific article published on January 1997

Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55

scientific article published on 24 December 2010

Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways

scientific article published on 27 May 2015

Membrane fluidity and fatty acid composition of phospholipids in erythrocyte membranes of patients with huntington disease

scientific article

Modification of opioid agonist binding by pertussis toxin

scientific article published in August 1987

Molecular cloning and expression of a delta-opioid receptor from rat brain

scientific journal article

Mutation studies of Ser7.39 and Ser2.60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7.

scientific article

Neurobiology of marijuana abuse.

scientific article

Pertussis toxin treatment modifies opiate action in the rat brain striatum

scientific article published in March 1985

Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy

scientific article published on 7 February 2015

Regulation of both preproenkephalin mRNA and its derived opioids by haloperidol--a method for measurement of peptides and mRNA in the same tissue extract

scientific article published in August 1990

Role for C-tail residues in delta opioid receptor downregulation

scientific article published in February 2000

Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine.

scientific article

Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor.

scientific article

The Endocannabinoids Anandamide and Virodhamine Modulate the Activity of the Candidate Cannabinoid Receptor GPR55

scientific article published on March 28, 2012

The Lysophosphatidylinositol Receptor GPR55 Modulates Pain Perception in the Periaqueductal Gray

scientific article published on 13 May 2015

The Two-pore channel (TPC) interactome unmasks isoform-specific roles for TPCs in endolysosomal morphology and cell pigmentation

scientific article

The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: insights gained from (E)- and (Z)-naphthylidene indenes.

scientific article published on December 1998

The endocannabinoid system as a target for the treatment of neurodegenerative disease

scientific article

Two-pore channels provide insight into the evolution of voltage-gated Ca2+ and Na+ channels.

scientific article

Unique Analogues of Anandamide: Arachidonyl Ethers and Carbamates and Norarachidonyl Carbamates and Ureas

scientific article published on 01 June 1999