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List of works by Niccola Funel

5'-nucleotidase cN-II emerges as a new predictive biomarker of response to gemcitabine/platinum combination chemotherapy in non-small cell lung cancer

scientific article published on 16 February 2018

A Model of a Zebrafish Avatar for Co-Clinical Trials

scientific article published on 13 March 2020

A polymorphism in the promoter is associated with EZH2 expression but not with outcome in advanced pancreatic cancer patients

scientific article

A propensity score-matched analysis of robotic versus open pancreatoduodenectomy for pancreatic cancer based on margin status

scientific article published on 25 June 2018

AKT1 and SELP polymorphisms predict the risk of developing cachexia in pancreatic cancer patients

scientific article

Adjuvant chemotherapy seems beneficial for invasive intraductal papillary mucinous neoplasms

scientific article published on 3 January 2013

Anti-diabetic properties of a non-conventional radical scavenger, as compared to pioglitazone and exendin-4, in streptozotocin-nicotinamide diabetic mice

scientific article published on 12 February 2014

Antiproliferative effects of novel aliphatic acetogenin analogs against aggressive solid tumor cell lines.

scientific article published on March 2011

Association between DNA-repair polymorphisms and survival in pancreatic cancer patients treated with combination chemotherapy.

scientific article published on 25 October 2011

Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients

scientific article published on 5 August 2016

Common genetic variants associated with pancreatic adenocarcinoma may also modify risk of pancreatic neuroendocrine neoplasms

scientific article published on 22 December 2017

Common genetic variants associated with pancreatic adenocarcinoma may also modify risk of pancreatic neuroendocrine neoplasms

scientific article published on 01 July 2018

Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer

scientific article published on 22 June 2015

Contrast enhancement pattern on multidetector CT predicts malignancy in pancreatic endocrine tumours

scientific article published on 02 December 2014

Correlation of basal EGFR expression with pancreatic cancer grading but not with clinical outcome after gemcitabine-based treatment

scientific article published on 31 December 2010

Critical role of laser microdissection for genetic, epigenetic and proteomic analyses in pancreatic cancer

scientific article

Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma

scientific article

Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line

scientific article published on 10 May 2019

Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing.

scientific article published on 17 March 2017

Dextran-catechin conjugate: a potential treatment against the pancreatic ductal adenocarcinoma

scientific article published on 24 May 2012

Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.

scientific article published on 18 February 2011

Does thyroid peroxidase provide an antigenic link between thyroid autoimmunity and breast cancer?

scientific article published on 15 October 2013

Dystrophic-like alterations characterize orbicularis oris and palatopharyngeal muscles in patients affected by cleft lip and palate

scientific article published on 21 August 2007

Ectopic expression of FSH receptor isoforms in neoplastic but not in endothelial cells from pancreatic neuroendocrine tumors.

scientific article published on 25 June 2012

Enhancement of the antiproliferative activity of gemcitabine by modulation of c-Met pathway in pancreatic cancer

scientific article published on January 2013

Evaluation of vascular infiltration in resected patients for pancreatic cancer: comparison among multidetector CT, intraoperative findings and histopathology

scientific article

Expression of SP7, RUNX1, DLX5, and CTNNB1 in human mesenchymal stem cells cultured on xenogeneic bone substitute as compared with machined titanium

scientific article

FOLFIRINOX and translational studies: Towards personalized therapy in pancreatic cancer

scientific article

Galectin-4 expression is associated with reduced lymph node metastasis and modulation of Wnt/β-catenin signalling in pancreatic adenocarcinoma

scientific article

Genetic determinants of telomere length and risk of pancreatic cancer: a PANDoRA study

scientific article published on 12 November 2018

Genetic susceptibility to pancreatic cancer and its functional characterisation: the PANcreatic Disease ReseArch (PANDoRA) consortium

scientific article published in December 2012

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

scientific article

Hepatitis C virus infection and human pancreatic beta-cell dysfunction

scientific article published on April 2005

High-throughput microRNA (miRNAs) arrays unravel the prognostic role of MiR-211 in pancreatic cancer

scientific article

Histopathologic evaluation of liver metastases from colorectal cancer in patients treated with FOLFOXIRI plus bevacizumab.

scientific article published on 23 May 2013

Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

scientific article published on 14 May 2010

Integrated molecular analysis to investigate the role of microRNAs in pancreatic tumour growth and progression

scientific article published on February 2015

Interfacing polymeric scaffolds with primary pancreatic ductal adenocarcinoma cells to develop 3D cancer models

scientific article published on January 2014

Laser microdissection and primary cell cultures improve pharmacogenetic analysis in pancreatic adenocarcinoma.

scientific article

Lipoprotein glomerulopathy: first report of 2 not consanguineous Italian men from the same town

scientific article published on May 2011

Liquid biopsies to optimize therapeutic efficacy in unresponsive lung cancer patients

scientific article published on 04 July 2018

Loss of 18q22.3 involving the carboxypeptidase of glutamate-like gene is associated with poor prognosis in resected pancreatic cancer

scientific article published on 29 November 2011

Loss of heterozygosity status of D9S105 marker is associated with downregulation of Krüppel-like factor 4 expression in pancreatic ductal adenocarcinoma and pancreatic intraepithelial lesions

scientific article

MET as a potential target for the treatment of upper gastrointestinal cancers: characterization of novel c-Met inhibitors from bench to bedside

scientific article published on January 2014

Magnetic carbon nanotubes: a new tool for shepherding mesenchymal stem cells by magnetic fields

scientific article published on 01 January 2011

MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma-a step towards personalized therapy

scientific article

MicroRNA-21 in pancreatic cancer: correlation with clinical outcome and pharmacologic aspects underlying its role in the modulation of gemcitabine activity.

scientific article

MicroRNAs cooperatively inhibit a network of tumor suppressor genes to promote pancreatic tumor growth and progression

scientific article published on 9 October 2013

Microdissected pancreatic cancer proteomes reveal tumor heterogeneity and therapeutic targets

scientific article published on 07 July 2020

Multidetector CT in the evaluation of retroperitoneal fat tissue infiltration in ductal adenocarcinoma of the pancreatic head: correlation with histopathological findings

scientific article published on 18 July 2009

Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas

scientific article

Myoclonus epilepsy, retinitis pigmentosa, leukoencephalopathy and cerebral calcifications associated with a novel m.5513G>A mutation in the MT-TW gene.

scientific article published on 3 April 2018

Nonsense mutation in exon 2 of the alpha-galactosidase A gene in a patient with Fabry disease

article

PTEN expression and KRAS mutations on primary tumors and metastases in the prediction of benefit from cetuximab plus irinotecan for patients with metastatic colorectal cancer.

scientific article published on 27 April 2009

Pancreatic cancer

scientific article published on 24 March 2015

Pancreatoduodenectomy without Vascular Resection in Patients with Primary Resectable Adenocarcinoma and Unilateral Venous Contact: A Matched Case Study

scientific article published on 25 November 2018

Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger

scientific article published on 29 May 2010

Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer

scientific article published on 06 January 2017

Prognostic factors for pancreatic neuroendocrine neoplasms (pNET) and the risk of small non-functioning pNET

scientific article published on 12 December 2014

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies.

scientific article published on 12 April 2016

Proteomic analysis of gemcitabine-resistant pancreatic cancer cells reveals that microtubule-associated protein 2 upregulation associates with taxane treatment

scientific article published on 10 May 2019

Robotic pancreatoduodenectomy with vascular resection.

scientific article

Role of CYB5A in pancreatic cancer prognosis and autophagy modulation

scientific article published on 03 December 2013

Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells.

scientific article

Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools ⬇️

scientific article

Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma

scientific article published on 20 December 2018

Study of apoptosis induction and deoxycytidine kinase/cytidine deaminase modulation in the synergistic interaction of a novel ceramide analog and gemcitabine in pancreatic cancer cells.

scientific article published on June 2010

Sub-micrometric liposomes as drug delivery systems in the treatment of periodontitis

scientific article published in July 2012

Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia

scientific article published on 31 October 2013

TERT gene harbors multiple variants associated with pancreatic cancer susceptibility

scientific article

TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression.

scientific article

The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy-Letter.

scientific article

The emerging role of liquid biopsy in diagnosis, prognosis and treatment monitoring of pancreatic cancer

scientific article published on 06 December 2018

The good, the bad and the ugly: a tale of miR-101, miR-21 and miR-155 in pancreatic intraductal papillary mucinous neoplasms

scientific article

The odd case of a small and mucinous-like acinar cell cystoadenocarcinoma of the pancreas

scientific article published on 27 July 2012

The role of miR-21 and miR-211 on MMP9 regulation in pancreatic ductal adenocarcinoma: cooperation in invasiveness behaviors?

scientific article published in January 2015

Transcription analysis of human equilibrative nucleoside transporter-1 predicts survival in pancreas cancer patients treated with gemcitabine.

scientific article

Triticum vulgare Extract Modulates Protein-Kinase B and Matrix Metalloproteinases 9 Protein Expression in BV-2 Cells: Bioactivity on Inflammatory Pathway Associated with Molecular Mechanism Wound Healing

scientific article published on 27 February 2020

Triticum vulgare extract exerts an anti-inflammatory action in two in vitro models of inflammation in microglial cells.

scientific article

Ukrain affects pancreas cancer cell phenotype in vitro by targeting MMP-9 and intra-/extracellular SPARC expression

scientific article published on 23 October 2010

Uridine Cytidine Kinase 2 as a Potential Biomarker for Treatment with RX-3117 in Pancreatic Cancer

scientific article published on 01 July 2019

Vascular dysfunction in a mouse model of Rett syndrome and effects of curcumin treatment

scientific article

miR-211 modulates gemcitabine activity through downregulation of ribonucleotide reductase and inhibits the invasive behavior of pancreatic cancer cells

scientific article

microRNAs with prognostic significance in pancreatic ductal adenocarcinoma: A meta-analysis

scientific article published on 19 May 2015

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