List of works - Michael Tatham

A fluorescence-resonance-energy-transfer-based protease activity assay and its use to monitor paralog-specific small ubiquitin-like modifier processing

scientific article published on 04 January 2007

Comparative proteomic analysis identifies a role for SUMO in protein quality control

scientific article

Detection of protein SUMOylation in vivo

scientific article published on 03 September 2009

FRET-based in vitro assays for the analysis of SUMO protease activities

scientific article published on January 2009

Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction

scientific article

High-stringency tandem affinity purification of proteins conjugated to ubiquitin-like moieties

scientific article

Identification of a substrate recognition site on Ubc9.

scientific article published on 4 March 2002

In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy

scientific article

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

scientific article

Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

scientific article

Purification and identification of endogenous polySUMO conjugates

scientific article

Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathway

scientific article published on April 2008

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

scientific article

Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation

scientific article (publication date: 26 August 2003)

Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex

scientific article

SUMO and transcriptional regulation

scientific journal article

SUMO protease SENP1 induces isomerization of the scissile peptide bond

scientific article

SUMOylation of the GTPase Rac1 is required for optimal cell migration

scientific article

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

scientific article published on 30 April 2021

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

scientific article

System-wide changes to SUMO modifications in response to heat shock

scientific article

The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε

scientific article published on 25 November 2019

The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells

scientific article published on 22 December 2020

Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection

scientific journal article

List of works by Michael Tatham

A fluorescence-resonance-energy-transfer-based protease activity assay and its use to monitor paralog-specific small ubiquitin-like modifier processing

Comparative proteomic analysis identifies a role for SUMO in protein quality control

Detection of protein SUMOylation in vivo

FRET-based in vitro assays for the analysis of SUMO protease activities

Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction

High-stringency tandem affinity purification of proteins conjugated to ubiquitin-like moieties

Identification of a substrate recognition site on Ubc9.

In vivo identification of human small ubiquitin-like modifier polymerization sites by high accuracy mass spectrometry and an in vitro to in vivo strategy

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

Purification and identification of endogenous polySUMO conjugates

Quantitative analysis of multi-protein interactions using FRET: application to the SUMO pathway

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation

Role of two residues proximal to the active site of Ubc9 in substrate recognition by the Ubc9.SUMO-1 thiolester complex

SUMO and transcriptional regulation

SUMO protease SENP1 induces isomerization of the scissile peptide bond

SUMOylation of the GTPase Rac1 is required for optimal cell migration

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Structure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysis

System-wide changes to SUMO modifications in response to heat shock

The S phase checkpoint promotes the Smc5/6 complex dependent SUMOylation of Pol2, the catalytic subunit of DNA polymerase ε

The SUMOylation pathway suppresses arbovirus replication in Aedes aegypti cells

Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection