List of works - Gunnar Brinkmalm

A Parallel Reaction Monitoring Mass Spectrometric Method for Analysis of Potential CSF Biomarkers for Alzheimer's Disease

scientific article

A novel pathway for amyloid precursor protein processing

scientific article

Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase

scholarly article by Bruno Becker published in August 2018

Amyloid-β metabolism in Niemann-Pick C disease models and patients

scientific article

An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid

scientific article

Analytical approaches to improved characterization of substitution in hydroxypropyl cellulose

scientific article

Assignment of saccharide identities through analysis of oxonium ion fragmentation profiles in LC-MS/MS of glycopeptides.

scientific article published on 17 November 2014

BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system

scientific article

Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts

scientific article published on 01 May 2020

CSF Presenilin-1 complexes are increased in Alzheimer's disease

scientific article published on 06 August 2013

Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis

scientific article published on 15 October 2012

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

scientific article published in December 2014

Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry

scientific article

Characterization of chemical substitution of hydroxypropyl cellulose using enzymatic degradation

scientific article published in January 2006

Characterization of monomeric and soluble aggregated Aβ in Down’s syndrome and Alzheimer’s disease brains

scientific article published in 2021

Characterization of tau in cerebrospinal fluid using mass spectrometry

scientific article published on 20 March 2008

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls

scientific article published on July 2015

Clinical proteomics in neurodegenerative disorders

scientific article published on 13 February 2008

Comprehensive analysis of the substituent distribution in hydroxyethyl celluloses by quantitative MALDI-ToF-MS.

scientific article published in June 2006

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis

scientific article published on 27 December 2018

Delayed electron emission from electronically sputtered C60- ions

scientific article published on 01 October 1994

Derivatization using dimethylamine for tandem mass spectrometric structure analysis of enzymatically and acidically depolymerized methyl cellulose

scientific article

Development of a size exclusion chromatography method for the determination of molar mass for poloxamers

scientific article

Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease

scientific article

Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer's and Parkinson's disease

scientific article published on 14 September 2019

Enrichment of glycopeptides for glycan structure and attachment site identification

scientific article published on 18 October 2009

Enzymatic degradation of carboxymethyl cellulose hydrolyzed by the endoglucanases Cel5A, Cel7B, and Cel45A from Humicola insolens and Cel7B, Cel12A and Cel45Acore from Trichoderma reesei

scientific article

Enzyme-aided investigation of the substituent distribution in cationic potato amylopectin starch

scientific article published in December 2003

Expanding the cerebrospinal fluid endopeptidome

scientific article published on 03 January 2017

Explorative and targeted neuroproteomics in Alzheimer's disease

scientific article

Formation of fullerenes in MeV-ion sputtering from organic solids

article

Heteromers of amyloid precursor protein in cerebrospinal fluid

scientific article

Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments

Identification of novel APP/Abeta isoforms in human cerebrospinal fluid

scientific article

Identification of novel N-terminal fragments of amyloid precursor protein in cerebrospinal fluid

scientific article published on 25 June 2009

Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS method

scientific article

Improved chemical analysis of cellulose ethers using dialkylamine derivatization and mass spectrometry

scientific article

Improved matrix-assisted laser desorption/ionisation sample preparation of a partially depolymerised cellulose derivative by continuous spray deposition and interfacing with size-exclusion chromatography

scientific article

Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ.

scientific article published on 2 November 2017

Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders

scientific article published on 3 October 2017

Mass spectrometric characterization of amyloid-β species in the 7PA2 cell model of Alzheimer's disease

scientific article

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease

scientific article published on 24 April 2010

New approaches to the analysis of enzymatically hydrolyzed methyl cellulose. Part 1. Investigation of the influence of structural parameters on the extent of degradation

scientific article published in May 2006

New approaches to the analysis of enzymatically hydrolyzed methyl cellulose. Part 2. Comparison of various enzyme preparations

scientific article published in May 2006

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

scientific article published on 13 December 2018

P3-071: Mass spectrometric characterization of tau in cerebrospinal fluid

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

scientific article published on 10 July 2020

Proteomic studies of cerebrospinal fluid biomarkers of Alzheimer's disease: an update

scientific article published on 25 September 2017

Proteomics profiling of single organs from individual adult zebrafish

scientific article published in June 2010

Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative diseases

scientific article published on January 2009

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology

scientific article published in 2019

SILAC zebrafish for quantitative analysis of protein turnover and tissue regeneration

scientific article published on 18 August 2011

SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease

scientific article

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

scientific article

Sample preparation effects in matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry of partially depolymerised carboxymethyl cellulose

scientific article

Sample preparation effects in matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry of partially depolymerised methyl cellulose

scientific article

Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid

scientific article

Soluble amyloid precursor protein α and β in CSF in Alzheimer's disease

scientific article

Substituent distribution and clouding behavior of hydroxypropyl methyl cellulose analyzed using enzymatic degradation.

scientific article published on December 2006

Synthesis aided structural determination of amyloid-β(1-15) glycopeptides, new biomarkers for Alzheimer's disease.

scientific article

Synthetic standard aided quantification and structural characterization of amyloid-beta glycopeptides enriched from cerebrospinal fluid of Alzheimer's disease patients

scientific article published on 02 April 2019

Targeting LAMP2 in human cerebrospinal fluid with a combination of immunopurification and high resolution parallel reaction monitoring mass spectrometry

scientific article published on 25 February 2016

Targeting synaptic pathology with a novel affinity mass spectrometry approach

scientific article published on 27 June 2014

The amyloid-β degradation pattern in plasma--a possible tool for clinical trials in Alzheimer's disease

scientific article

The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species.

scientific article

The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease

scientific article published on 03 October 2016

Update on biomarkers for amyloid pathology in Alzheimer's disease

scientific article published on 15 June 2018

List of works by Gunnar Brinkmalm

A Parallel Reaction Monitoring Mass Spectrometric Method for Analysis of Potential CSF Biomarkers for Alzheimer's Disease

A novel pathway for amyloid precursor protein processing

Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by Calpain-1 and prolyl endopeptidase

Amyloid-β metabolism in Niemann-Pick C disease models and patients

An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid

Analytical approaches to improved characterization of substitution in hydroxypropyl cellulose

Assignment of saccharide identities through analysis of oxonium ion fragmentation profiles in LC-MS/MS of glycopeptides.

BACE1 inhibition induces a specific cerebrospinal fluid β-amyloid pattern that identifies drug effects in the central nervous system

Blood phosphorylated tau 181 as a biomarker for Alzheimer's disease: a diagnostic performance and prediction modelling study using data from four prospective cohorts

CSF Presenilin-1 complexes are increased in Alzheimer's disease

Cerebrospinal fluid biomarkers of β-amyloid metabolism in multiple sclerosis

Cerebrospinal fluid levels of the synaptic protein neurogranin correlates with cognitive decline in prodromal Alzheimer's disease

Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry

Characterization of chemical substitution of hydroxypropyl cellulose using enzymatic degradation

Characterization of monomeric and soluble aggregated Aβ in Down’s syndrome and Alzheimer’s disease brains

Characterization of tau in cerebrospinal fluid using mass spectrometry

Characterization of the postsynaptic protein neurogranin in paired cerebrospinal fluid and plasma samples from Alzheimer's disease patients and healthy controls

Clinical proteomics in neurodegenerative disorders

Comprehensive analysis of the substituent distribution in hydroxyethyl celluloses by quantitative MALDI-ToF-MS.

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis

Delayed electron emission from electronically sputtered C60- ions

Derivatization using dimethylamine for tandem mass spectrometric structure analysis of enzymatically and acidically depolymerized methyl cellulose

Development of a size exclusion chromatography method for the determination of molar mass for poloxamers

Effects of gamma-secretase inhibition on the amyloid beta isoform pattern in a mouse model of Alzheimer's disease

Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer's and Parkinson's disease

Enrichment of glycopeptides for glycan structure and attachment site identification

Enzymatic degradation of carboxymethyl cellulose hydrolyzed by the endoglucanases Cel5A, Cel7B, and Cel45A from Humicola insolens and Cel7B, Cel12A and Cel45Acore from Trichoderma reesei

Enzyme-aided investigation of the substituent distribution in cationic potato amylopectin starch

Expanding the cerebrospinal fluid endopeptidome

Explorative and targeted neuroproteomics in Alzheimer's disease

Formation of fullerenes in MeV-ion sputtering from organic solids

Heteromers of amyloid precursor protein in cerebrospinal fluid

Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments

Identification of novel APP/Abeta isoforms in human cerebrospinal fluid

Identification of novel N-terminal fragments of amyloid precursor protein in cerebrospinal fluid

Identification of novel α-synuclein isoforms in human brain tissue by using an online nanoLC-ESI-FTICR-MS method

Improved chemical analysis of cellulose ethers using dialkylamine derivatization and mass spectrometry

Improved matrix-assisted laser desorption/ionisation sample preparation of a partially depolymerised cellulose derivative by continuous spray deposition and interfacing with size-exclusion chromatography

Low-dose γ-secretase inhibition increases secretion of Aβ peptides and intracellular oligomeric Aβ.

Mass Spectrometric Analysis of Cerebrospinal Fluid Ubiquitin in Alzheimer's Disease and Parkinsonian Disorders

Mass spectrometric characterization of amyloid-β species in the 7PA2 cell model of Alzheimer's disease

Mass spectrometric characterization of brain amyloid beta isoform signatures in familial and sporadic Alzheimer's disease

New approaches to the analysis of enzymatically hydrolyzed methyl cellulose. Part 1. Investigation of the influence of structural parameters on the extent of degradation

New approaches to the analysis of enzymatically hydrolyzed methyl cellulose. Part 2. Comparison of various enzyme preparations

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

P3-071: Mass spectrometric characterization of tau in cerebrospinal fluid

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

Proteomic studies of cerebrospinal fluid biomarkers of Alzheimer's disease: an update

Proteomics profiling of single organs from individual adult zebrafish

Proteomics/peptidomics tools to find CSF biomarkers for neurodegenerative diseases

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology

SILAC zebrafish for quantitative analysis of protein turnover and tissue regeneration

SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease

Sample Preparation for Endopeptidomic Analysis in Human Cerebrospinal Fluid

Sample preparation effects in matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry of partially depolymerised carboxymethyl cellulose

Sample preparation effects in matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry of partially depolymerised methyl cellulose

Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid beta-peptides in human cerebrospinal fluid

Soluble amyloid precursor protein α and β in CSF in Alzheimer's disease

Substituent distribution and clouding behavior of hydroxypropyl methyl cellulose analyzed using enzymatic degradation.

Synthesis aided structural determination of amyloid-β(1-15) glycopeptides, new biomarkers for Alzheimer's disease.

Synthetic standard aided quantification and structural characterization of amyloid-beta glycopeptides enriched from cerebrospinal fluid of Alzheimer's disease patients

Targeting LAMP2 in human cerebrospinal fluid with a combination of immunopurification and high resolution parallel reaction monitoring mass spectrometry

Targeting synaptic pathology with a novel affinity mass spectrometry approach

The amyloid-β degradation pattern in plasma--a possible tool for clinical trials in Alzheimer's disease

The aqueous phase of Alzheimer's disease brain contains assemblies built from ∼4 and ∼7 kDa Aβ species.

The pre-synaptic vesicle protein synaptotagmin is a novel biomarker for Alzheimer's disease

Update on biomarkers for amyloid pathology in Alzheimer's disease