List of works by Peter Koopman

1 Sry and Mammalian Sex Determination

A cell-autonomous role for WT1 in regulating Sry in vivo

scientific article published on 23 June 2009

A critical time window of Sry action in gonadal sex determination in mice.

scientific article published on 26 November 2008

A differentiation-defective concanavalin-A-resistant variant of a pluripotent embryonal carcinoma cell line.

scientific article published in January 1987

A factor produced by feeder cells which inhibits embryonal carcinoma cell differentiation. Characterization and partial purification.

scientific article published in September 1984

A high-resolution anatomical ontology of the developing murine genitourinary tract.

scientific article

A male-specific role for p38 mitogen-activated protein kinase in germ cell sex differentiation in mice

scientific article

A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development

scientific article published on 9 November 2011

A piggyBac transposon- and gateway-enhanced system for efficient BAC transgenesis

scientific article published on 25 June 2014

A site-specific, single-copy transgenesis strategy to identify 5' regulatory sequences of the mouse testis-determining gene Sry

scientific article

A subtractive gene expression screen suggests a role forvanin-1 in testis development in mice

scholarly article by Josephine Bowles et al published 2000 in Genesis

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries

scientific article published on 19 February 2016

Aard is specifically up-regulated in Sertoli cells during mouse testis differentiation

scientific article published on 01 January 2007

Aetiology of the skeletal dysmorphology syndrome campomelic dysplasia: expression of the Sox9 gene during chondrogenesis in mouse embryos.

scientific article published in June 1996

Alternative splicing of the first nucleotide binding fold of CFTR in mouse testes is associated with specific stages of spermatogenesis.

scientific article published on April 1994

An H-YDb epitope is encoded by a novel mouse Y chromosome gene

scientific article

Analysis of gene function in cultured embryonic mouse gonads using nucleofection.

scientific article published on 22 November 2010

Antagonism of the testis- and ovary-determining pathways during ovotestis development in mice

scientific article published on 06 March 2009

Antagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in mice

scientific journal article

Building the mammalian testis: origins, differentiation, and assembly of the component cell populations

scientific article

CITED2 mutations potentially cause idiopathic premature ovarian failure.

scientific article published on 16 June 2012

CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary

scientific article published on 20 March 2006

Cbx2, a polycomb group gene, is required for Sry gene expression in mice

scientific article published on 20 December 2011

Cell cycle analysis of fetal germ cells during sex differentiation in mice

scientific article published on 31 July 2009

Cell cycle control of germ cell differentiation

scientific article published on January 2011

Characterisation of urogenital ridge gene expression in the human embryonal carcinoma cell line NT2/D1.

scientific article

Circular transcripts of the testis-determining gene Sry in adult mouse testis

scientific article published on June 1993

Cloning and expression of candidate sexual development genes in the cane toad (Bufo marinus).

scientific article published in September 2009

Cloning and functional analysis of the Sry-related HMG box gene, Sox18

scientific journal article

Comparative analysis of anti-mouse SRY antibodies.

scientific article

Comparative proteomic analysis to study molecular events during gonad development in mice.

scientific article published in April 2006

Conservation analysis of sequences flanking the testis-determining gene Sry in 17 mammalian species

scientific article

Conserved regulatory modules in the Sox9 testis-specific enhancer predict roles for SOX, TCF/LEF, Forkhead, DMRT, and GATA proteins in vertebrate sex determination

scientific article published on 16 July 2009

Control of mammalian germ cell entry into meiosis

scientific article published on 27 September 2013

Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo

scientific article published on 19 December 2013

Coordinated expression ofscleraxis andSox9 genes during embryonic development of tendons and cartilage

scientific article published on 01 July 2002

Copy number variation in patients with disorders of sex development due to 46,XY gonadal dysgenesis

scientific article

Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone

scientific article published on February 2017

Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors.

scientific article published on 18 November 2015

Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function

scientific article

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

scientific journal article

Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome

Delayed Sry and Sox9 expression in developing mouse gonads underlies B6-Y(DOM) sex reversal.

scientific article published in February 2005

Developmental biology: gender benders.

scientific article published in November 2003

Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression.

scientific article published in May 2014

Dexamethasone enhances SOX9 expression in chondrocytes

scientific article published on 01 June 2001

Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort

scientific article

Dppa3 is a marker of pluripotency and has a human homologue that is expressed in germ cell tumours.

scientific article

Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development

scientific article

Endogenous Nodal signaling regulates germ cell potency during mammalian testis development

scientific journal article

Endothelial cell migration directs testis cord formation

scientific article published on 7 November 2008

Epigenetic regulation of mouse sex determination by the histone demethylase Jmjd1a

scientific article published on September 2013

Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development.

scientific article published in July 2003

Evaluation of candidate markers for the peritubular myoid cell lineage in the developing mouse testis.

scientific article published in October 2005

Ex vivo magnetofection: a novel strategy for the study of gene function in mouse organogenesis

scientific article

Exclusion of Sox9 as a candidate for the mouse mutant tail-short

scientific article

Expansion of the Ago gene family in the teleost clade

scientific article published on 11 May 2011

Expression and functional analysis of Dkk1 during early gonadal development.

scientific article

Expression of a candidate sex-determining gene during mouse testis differentiation.

scientific article

Expression of a linear Sry transcript in the mouse genital ridge ⬇️

scientific article published on August 1, 1995

Expression of distinct RNAs from 3' untranslated regions

scientific article

Expression of the tudor-related gene Tdrd5 during development of the male germline in mice

scientific article

Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes

scientific article

Expression-based strategies for discovery of genes involved in testis and ovary development

scientific article

Extensive vascularization of developing mouse ovaries revealed by caveolin-1 expression

scientific article published in September 2002

FGF9 suppresses meiosis and promotes male germ cell fate in mice

scientific article published on September 2010

FGFR2 mutation in 46,XY sex reversal with craniosynostosis

scientific article

FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development

scientific article published on 17 November 2010

FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice

scientific article published on 22 January 2014

Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1.

scientific article published on 27 February 2015

Functional analysis of the SRY-KRAB interaction in mouse sex determination

article

GUDMAP – An Online GenitoUrinary Resource

GUDMAP – An Online GenitoUrinary Resource

Gene editing of the multi-copy H2A.B gene and its importance for fertility

article

Genesis and expansion of metazoan transcription factor gene classes.

scientific article published on 21 February 2008

Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice

scientific article

Genetic basis of human testicular germ cell cancer: insights from the fruitfly and mouse

scientific article

Genome-Wide Off-Target Analysis in CRISPR-Cas9 Modified Mice and Their Offspring

scientific article published on 05 November 2019

Genomic screen for genes involved in mammalian craniofacial development

scientific article

Germ cells enter meiosis in a rostro-caudal wave during development of the mouse ovary

scientific article published in August 2004

Germ cells influence cord formation and Leydig cell gene expression during mouse testis development

scientific article published on 5 December 2015

Global survey of protein expression during gonadal sex determination in mice

scientific article

Gonad development: Signals for sex

article

Gonadal Sex Determination and Differentiation

Gonadal defects in Cited2-mutant mice indicate a role for SF1 in both testis and ovary differentiation

scientific article published in January 2010

Gonads–Müllerian Ducts

HMG box transcription factor gene Hbp1 is expressed in germ cells of the developing mouse testis

scientific article published in June 2004

Hypoxia induces chondrocyte-specific gene expression in mesenchymal cells in association with transcriptional activation of Sox9.

scientific article published on September 2005

Identification of novel markers of mouse fetal ovary development

scientific article

Identification of suitable normalizing genes for quantitative real-time RT-PCR analysis of gene expression in fetal mouse gonads.

scientific article published on 11 September 2009

Inhibition of SRY-calmodulin complex formation induces ectopic expression of ovarian cell markers in developing XY gonads.

scientific article published on 10 May 2011

Initiating meiosis: the case for retinoic acid

scientific article published on 14 February 2012

Insights into the Aetiology of Ovotesticular DSD from Studies of Mouse Ovotestes

scientific article published on 01 January 2011

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility

scientific article published on 5 January 2016

Involvement of homeobox genes in mammalian sexual development

scientific article published on January 2007

Location of the genes controlling H-Y antigen expression and testis determination on the mouse Y chromosome.

scientific article

Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse

scientific journal article

Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice.

scientific article published on 10 January 2012

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination

scientific article

Male development of chromosomally female mice transgenic for Sry.

scientific article published in May 1991

Male sex determination: insights into molecular mechanisms

scientific article

Male-specific expression of Aldh1a1 in mouse and chicken fetal testes: implications for retinoid balance in gonad development.

scientific article published in August 2009

Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators

scientific article (publication date: August 2002)

Mice Lacking Hbp1 Function Are Viable and Fertile

scientific article

Mice null for sox18 are viable and display a mild coat defect

scientific article

Molecular characterization of the Bidder's organ in the cane toad (Bufo marinus).

scientific article published in September 2010

Molecular characterization of three gonad cell lines

scientific article published on January 2003

Mouse germ cell development: from specification to sex determination

scientific article published on 28 December 2009

Mutations in Sox18 underlie cardiovascular and hair follicle defects in ragged mice

scientific journal article

New clues to the puzzle of mammalian sex determination

scientific article

New insights into SRY regulation through identification of 5' conserved sequences

scientific article

Nodal/Cripto signaling in fetal male germ cell development: implications for testicular germ cell tumors

scientific article published on January 2013

Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

scientific article

Nr5a1 suppression during the fetal period optimizes ovarian development by fine-tuning of Notch signaling

Of sex and determination: marking 25 years of Randy, the sex-reversed mouse

scientific article published in May 2016

On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?

scientific article

Onset of meiosis in the chicken embryo; evidence of a role for retinoic acid

scientific article published on 17 September 2008

Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes

scientific article

Origin and possible roles of the Sox8 transcription factor gene during sexual development

scientific article published on January 2003

Osteopontin and related SIBLING glycoprotein genes are expressed by Sertoli cells during mouse testis development.

scientific article published in August 2005

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

scientific article published on 31 January 2017

Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators

scientific article (publication date: 15 November 2000)

Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development

scientific article

Pluripotent differentiation of single F9 embryonal carcinoma cells.

scientific article published in February 1987

Precious cargo: regulation of sex-specific germ cell development in mice

scientific article published on 31 August 2012

Preface

Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice

scientific journal article

Profiles of gonadal gene expression in the developing bovine embryo

scientific article published on 21 October 2009

Prokr2-deficient mice display vascular dysmorphology of the fetal testes: potential implications for Kallmann syndrome aetiology.

scientific article published in January 2011

Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads

scientific article published on October 2010

Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells

scientific article published on 8 April 2015

RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus

scientific article published on 17 March 2015

RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis.

scientific article published on 8 September 2017

ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation

scientific article

Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos

scientific article

Redd1 is a novel marker of testis development but is not required for normal male reproduction

scientific article published on 11 July 2012

Reduced Activity of SRY and its Target Enhancer Sox9-TESCO in a Mouse Species with X*Y Sex Reversal

scientific article published on 03 February 2017

Redundant roles of Sox17 and Sox18 in early cardiovascular development of mouse embryos

scientific journal article

Redundant roles of Sox17 and Sox18 in postnatal angiogenesis in mice

scientific journal article

Regulation of Amh during sex determination in chickens: Sox gene expression in male and female gonads.

scientific article published in September 2005

Regulation of germ cell meiosis in the fetal ovary

scientific article published on January 2012

Regulation of male sexual development by Sry and Sox9.

scientific article

Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice

scientific article published on 28 October 2009

Retinoic acid, meiosis and germ cell fate in mammals

scientific article (publication date: October 2007)

Retinoid signaling determines germ cell fate in mice

scientific journal article

SOX18 directly interacts with MEF2C in endothelial cells

scientific journal article

SOX30 is required for male fertility in mice

scientific article published on 15 December 2017

SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice

scientific article published on 21 January 2017

SOX8 is expressed during testis differentiation in mice and synergizes with SF1 to activate the Amh promoter in vitro

scientific journal article

SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse

scientific journal article

SOX9 directly regulates the type-II collagen gene

scientific journal article

SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development.

scientific article published on 4 August 2016

SOX9 regulates microRNA miR-202-5p/3p expression during mouse testis differentiation

scientific article published on 15 August 2013

SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development.

scientific article published on 2 February 2007

SRY protein function in sex determination: thinking outside the box.

scientific article published on January 2012

SRY, Sex Determination and Gonadal Differentiation

Searching for missing pieces of the sex-determination puzzle.

scientific article

Seeds of concern

scientific article published in Nature

Segmental territories along the cardinal veins generate lymph sacs via a ballooning mechanism during embryonic lymphangiogenesis in mice

scientific article

Sequence and expression of Sox-18 encoding a new HMG-box transcription factor.

scientific article

Sertoli cell differentiation and Y-chromosome activity: a developmental study of X-linked transgene activity in sex-reversed X/XSxra mouse embryos.

scientific article

Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination

scientific journal article

Seven new members of the Sox gene family expressed during mouse development

scientific article

Sex Determination and Gonadal Development

article

Sex Determination in the Mammalian Germline

scientific article

Sex Determination: The Fishy Tale of Dmrt1

scientific article published on 01 March 2003

Sex determination and gonadal development in mammals

scientific article published on January 2007

Sex determination in mammalian germ cells: extrinsic versus intrinsic factors

scientific article published on 15 April 2010

Sex determination: a tale of two Sox genes

scientific article

Sex determination: the power of DMRT1.

scientific article published on 12 October 2009

Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation

article

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

scientific article

Sox Genes: At the Heart of Endothelial Transcription

article

Sox factors transcriptionally regulate ROBO4 gene expression in developing vasculature in zebrafish

scientific article

Sox genes and cancer

scientific article published in January 2004

Sox10 gain-of-function causes XX sex reversal in mice: implications for human 22q-linked disorders of sex development.

scientific article published on 20 November 2009

Sox18 and Sox7 play redundant roles in vascular development

scientific article published on 19 December 2007

Sox18 induces development of the lymphatic vasculature in mice

scientific journal article

Sox18 mutations in theragged mouse allelesragged-like andopossum

article

Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice

scientific journal article

Sox8 and Sertoli-cell Function

article

Sox8 is a critical regulator of adult Sertoli cell function and male fertility

scientific journal article

Sox8 is expressed at similar levels in gonads of both sexes during the sex determining period in turtles

scientific article

Sox9-dependent expression of Gstm6 in Sertoli cells during testis development in mice

scientific article published on 19 December 2008

SoxF genes: Key players in the development of the cardio-vascular system

scientific article published on 03 September 2009

Spatially dynamic expression ofSry in mouse genital ridges

scientific article published on 01 June 2001

Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles

scientific article

Sry and Sox9: mammalian testis-determining genes

article

Sry and Sox9: mammalian testis-determining genes.

scientific article

Sry and the hesitant beginnings of male development

scientific article

Sry requires a CAG repeat domain for male sex determination in Mus musculus

scientific article published in August 1999

Sry: the master switch in mammalian sex determination

scientific article

Structure-function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determination

scientific article

Switching on sex: transcriptional regulation of the testis-determining gene Sry

scientific article

Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.

scientific article

Testis development, fertility, and survival in Ethanolamine kinase 2-deficient mice

scientific article published on 28 August 2008

Testis-determining factor and Y-linked sex reversal ⬇️

scientific article published on June 1, 1991

The 7 Sexes: Biology of Sex Determination. By Elof Axel Carlson. xviii + 238 pp. Bloomington, IN: Indiana University Press. 2013. $35.00 (cloth), $29.99 (ebook)

The Curious World of Gonadal Development in Mammals

scientific article published on 17 February 2016

The HMG box transcription factor gene Sox14 marks a novel subset of ventral interneurons and is regulated by sonic hedgehog.

scientific article published in March 2000

The RNA-binding protein Musashi-2 (MSI2) controls mRNA processing and translational regulation via interactions with SFPQ and PIWIL1 during mammalian spermatogenesis

The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse

scientific article

The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos.

scientific article published in January 1995

The UTX gene escapes X inactivation in mice and humans

scientific article

The VCAM-1 gene that encodes the vascular cell adhesion molecule is a target of the Sry-related high mobility group box gene, Sox18

scientific journal article

The cerebellin 4 precursor gene is a direct target of SRY and SOX9 in mice

scientific article

The delicate balance between male and female sex determining pathways: potential for disruption of early steps in sexual development

scientific article published on 21 October 2009

The genetics and biology of vertebrate sex determination.

scientific article published in June 2001

The ins and outs of transcriptional control: nucleocytoplasmic shuttling in development and disease

scientific article published on January 2004

The makings of maleness: towards an integrated view of male sexual development

scientific article published on 11 July 2006

The matricellular protein SPARC is internalized in Sertoli, Leydig, and germ cells during testis differentiation

scientific article published in May 2006

The molecular genetics of sex determination and sex reversal in mammals

scientific article published on 08 October 2012

The mouse Sry locus harbors a cryptic exon that is essential for male sex determination

scientific article

The nuclear import factor importin α4 can protect against oxidative stress

scientific journal article

The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development

scientific article

The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development

scientific journal article

TheSry-Related GeneSox18Maps to Distal Mouse Chromosome 2

article

Three-dimensional imaging of Prox1-EGFP transgenic mouse gonads reveals divergent modes of lymphangiogenesis in the testis and ovary

scientific article (publication date: 2012)

Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development

scientific article

Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival

scientific article

Trans-activation and DNA-binding properties of the transcription factor, Sox-18

scientific journal article

Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis

scientific article

Tumor lymphangiogenesis as a potential therapeutic target

scientific article published on 16 February 2012

Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families

scientific article (publication date: August 2002)

Uncovering gene regulatory networks during mouse fetal germ cell development

scientific article

Up-regulation of SOX9 in human sex-determining region on the Y chromosome (SRY)-negative XX males

scientific article published on 06 November 2007

VEGFD regulates blood vascular development by modulating SOX18 activity.

scientific article published on 22 November 2013

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation

scientific journal article

Whole exome sequencing combined with linkage analysis identifies a novel 3 bp deletion in NR5A1

scientific article

Widespread expression of human alpha 1-antitrypsin in transgenic mice revealed by in situ hybridization.

scientific article published in January 1989

Widespread expression of the testis–determining gene SRY in a marsupial

article

Wnt signaling in ovarian development inhibits Sf1 activation of Sox9 via the Tesco enhancer

scientific article published on 29 November 2011

Z and W sex chromosomes in the cane toad (Bufo marinus).

scientific article published on 20 November 2009

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.

scientific article published in December 1989

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