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List of works by Martine F Roussel

A molecular fingerprint for medulloblastoma.

scientific article

A mouse model of the most aggressive subgroup of human medulloblastoma

scientific article published on February 2012

A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential

scientific article published on December 1988

A potential role for Elf-1 in terminal transferase gene regulation

scientific article published on November 1996

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8

scientific article

ABCG2 Transporter Expression Impacts Group 3 Medulloblastoma Response to Chemotherapy.

scientific article published on 21 July 2015

Activation of Src family kinases by colony stimulating factor-1, and their association with its receptor

scientific article

Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression

scientific article

Antibodies to distal carboxyl terminal epitopes in the v-fms-coded glycoprotein do not cross-react with the c-fms gene product

scientific article

Antibody-induced mitogenicity mediated by a chimeric CD2-c-fms receptor ⬇️

scientific article published on May 1, 1990

Apoptosis triggered by Myc-induced suppression of Bcl-X(L) or Bcl-2 is bypassed during lymphomagenesis

scientific journal article

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia

scholarly article

Arf induces p53-dependent and -independent antiproliferative genes.

scientific article published on March 2003

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

scientific article

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells

scientific article published on June 2010

Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture

scientific article

Avian leukaemia viruses and haematopoietic cell differentiation.

scientific article published on April 1980

Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

scientific journal article

Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer

scientific article published on 10 July 2020

Casein kinase 1δ is an APC/C(Cdh1) substrate that regulates cerebellar granule cell neurogenesis

scientific article

Cell transformation by avian defective leukaemia viruses.

scientific article published in November 1980

Cerebellum development and medulloblastoma

scientific article

Characterization of the oncogene (erb) of avian erythroblastosis virus and its cellular progenitor

scientific article

Cloning and chromosomal localization of the gene encoding human cyclin D-binding Myb-like protein (hDMP1)

scientific article

Cloning and expression of murine interleukin-1 receptor antagonist in macrophages stimulated by colony-stimulating factor 1 ⬇️

scientific article published on August 1, 1991

Complementation of growth factor receptor-dependent mitogenic signaling by a truncated type I phosphatidylinositol 4-phosphate 5-kinase.

scientific article published on December 1997

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

scientific article

Cross-species epigenetics identifies a critical role for VAV1 in SHH subgroup medulloblastoma maintenance

scientific article

Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivo

scientific article

Cyclin D1 expression in patients with multiple myeloma

scientific article published in 2000

Cyclin-dependent kinase inhibitors in the development of the central nervous system.

scientific article

DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.

scientific article published on February 1995

Data from CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

Development and cancer of the cerebellum

scientific article

Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation

scientific article published on 19 June 2015

Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells.

scientific article published on August 2001

E1A signaling to p53 involves the p19ARFtumor suppressor ⬇️

scientific article published on August 1, 1998

E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification

scientific article

EPEN-07. OVEREXPRESSION AND MUTATIONS OF CXORF67 IN ‘INFANT-TYPE’ POSTERIOR FOSSA TYPE-A (PFA) EPENDYMOMAS

article published in 2018

Embryonic Expression and Function of the Xenopus Ink4d Cyclin D-Dependent Kinase Inhibitor

scientific article

Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors.

scientific article published on 4 November 2017

Expression of INK4 inhibitors of cyclin D-dependent kinases during mouse brain development.

scientific article

Expression of c-Myc in response to colony-stimulating factor-1 requires mitogen-activated protein kinase kinase-1.

scientific article published on March 1999

Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme.

scientific article published in February 2000

Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines

scientific article published on June 1986

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging

scientific article published in July 1997

Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2 ⬇️

scientific article published on July 7, 1998

GE-40 * COMPARATIVE GENOMIC ANALYSES IDENTIFIES NON-SILENT MUTATIONS PRESENT IN BOTH MURINE AND HUMAN MEDULLOBLASTOMA

Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear

scientific article

Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors

scientific article published in March 2007

Genomic organization, chromosomal localization, and independent expression of human cyclin D genes

scientific article (publication date: July 1992)

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

scientific article

Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice.

scientific article published in September 2003

INK4d-deficient mice are fertile despite testicular atrophy

scientific article

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

scientific article (publication date: 16 October 1992)

Identification of Potent, Selective, and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators

scientific article published on 27 May 2021

Identification of small molecule activators of BMP signaling

scientific article

Inhibition of colony-stimulating factor-1 activity by monoclonal antibodies to the human CSF-1 receptor

scientific article published on May 1989

Ink4c is dispensable for tumor suppression in Myc-induced B-cell lymphomagenesis

scientific article published on 13 November 2006

Key Effectors of Signal Transduction and G 1 Progression

scientific article published on January 1, 1998

Loss of p53 induces changes in the behavior of subventricular zone cells: implication for the genesis of glial tumors.

scientific article published in January 2006

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

scientific article published on 09 August 2019

Medulloblastoma: advances and challenges. ⬇️

scientific article

Mitogenic signaling by colony-stimulating factor 1 and ras is suppressed by the ets-2 DNA-binding domain and restored by myc overexpression ⬇️

scientific article published on December 1, 1992

Miz1 is required to maintain autophagic flux.

scientific article published in January 2013

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas

scientific article published on 16 June 2018

Monoclonal Antibodies to Mammalian D-Type G1 Cyclins

scientific article published on 01 February 1994

Monoclonal antibodies to the human CSF-1 receptor (c-fms proto-oncogene product) detect epitopes on normal mononuclear phagocytes and on human myeloid leukemic blast cells

scientific article published on 01 February 1989

Monoclonal antibodies to the mouse p19(Arf) tumor suppressor protein

scientific article published on October 2004

Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

scientific article published on 7 June 2018

Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling ⬇️

scientific article published on September 26, 1991

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

scientific article (publication date: August 1998)

Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss.

scientific article

N-myc coordinates retinal growth with eye size during mouse development.

scientific article

N-terminal polyubiquitination and degradation of the Arf tumor suppressor

scientific article

New Concepts in Organ Site Research on Medulloblastoma: Genetics and Genomics ⬇️

scientific article published on August 1, 2010

Novel mutations target distinct subgroups of medulloblastoma.

scientific article

Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases

scientific article published on September 2000

Oncogenic potential of the c-FMS proto-oncogene (CSF-1 receptor).

scientific article

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

scientific article published on August 1993

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

scientific article

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma

scientific article published on 02 July 2021

Patient-derived orthotopic xenografts of pediatric brain tumors: a St. Jude resource

scientific article published on 10 June 2020

Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma

scientific article

Phosphorylation of Ets1 regulates the complementation of a CSF-1 receptor impaired in mitogenesis.

scientific article

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development

scientific article published on March 2008

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

scientific article

Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors

scientific article

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d

scientific journal article

Regulation of CYL/cyclin D genes by colony-stimulating factor 1

scientific article published on January 1, 1992

Regulation of cell growth and differentiation by the colony-stimulating factor 1 receptor

scientific article published on April 1, 1991

Rescue of defective mitogenic signaling by D-type cyclins.

scientific article

Rethinking brain tumors: the fourth Mouse Models of Human Cancers Consortium nervous system tumors workshop.

scientific article published on July 2008

Role of MYC in Medulloblastoma.

scientific article

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development

scientific article

Roles of p53 and p27(Kip1) in the regulation of neurogenesis in the murine adult subventricular zone

scientific article published on 7 September 2011

Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression

scientific article published on 21 October 2013

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

scientific article published on 11 June 2015

Stat3-dependent induction of p19INK4D by IL-10 contributes to inhibition of macrophage proliferation.

scientific article

Statistical significance threshold criteria for analysis of microarray gene expression data

scientific article

Structural Dissection of a Gating Mechanism Preventing Misactivation of Ubiquitin by NEDD8’s E1 † ‡

scientific article

Subgroup-specific structural variation across 1,000 medulloblastoma genomes

scientific article

Synthesis, post-translational processing, and autocrine transforming activity of a carboxylterminal truncated form of colony stimulating factor-1.

scientific article published on September 1987

TNF Counterbalances the Emergence of M2 Tumor Macrophages

scientific article published on 9 September 2015

TP53 and RB tumor suppressor pathways collaborate in retinoblastoma genesis

scientific article published in April 2007

The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma

scientific article published on 15 February 2006

The Cold Spring Harbor Laboratory meeting on tyrosine phosphorylation and cell signaling

scientific article published on 01 February 2000

The Interaction of Myc with Miz1 Defines Medulloblastoma Subgroup Identity

scientific journal article

The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity.

scientific article published on December 2000

The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain.

scientific article published in October 1999

The carboxy-terminal catalytic domain of the GTPase-activating protein inhibits nuclear signal transduction and morphological transformation mediated by the CSF-1 receptor

scientific article published on October 1991

The chimeric E2A-HLF transcription factor abrogates p53-induced apoptosis in myeloid leukemia cells

scientific article published in August 1998

The cyclin-dependent kinase inhibitors p19(Ink4d) and p27(Kip1) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit

scientific article published in March 2002

The distribution of endogenous chicken retrovirus sequences in the DNA of galliform birds does not coincide with avian phylogenetic relationships

scientific article published on July 1, 1979

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma

scientific article

The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

scientific article

The product of the c-fms proto-oncogene: a glycoprotein with associated tyrosine kinase activity

scientific article

The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation

scientific article

Three new types of viral oncogene of cellular origin specific for haematopoietic cell transformation ⬇️

scientific article published on October 11, 1979

Three new types of viral oncogenes in defective avian leukemia viruses. I. Specific nucleotide sequences of cellular origin correlate with specific transformation.

scientific article published in January 1980

Transforming activities of human CSF-1 receptors with different point mutations at codon 301 in their extracellular domains.

scientific article published in January 1990

Transforming activity of EWS/FLI is not strictly dependent upon DNA-binding activity

scientific article published on September 1999

Transforming potential of the c-fms proto-oncogene (CSF-1 receptor).

scientific article published on February 1987

Transmembrane orientation of glycoproteins encoded by the v-fms oncogene

scientific article published in April 1985

Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma

scientific article published on January 2009

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway

scientific article

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway

scientific article published on 28 June 2019

Viral RNAs from cells infected by an oncornavirus. I. Characterization of viral RNAs associated with cytoplasmic particles ⬇️

scientific article published on January 1, 1977

WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation

scientific article

Women in cancer research

scientific article published on 15 August 2019

[Origin of the transforming genes in avian acute leukemia retroviruses]

scientific article published in January 1980

p19(Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis.

scientific article published in February 2007

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