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List of works by Dirk Roggenbuck

A highly versatile microscope imaging technology platform for the multiplex real-time detection of biomolecules and autoimmune antibodies.

scientific article

A new dot immunoassay for simultaneous detection of celiac specific antibodies and IgA-deficiency

scientific article published in February 2012

A new line immunoassay for the multiparametric detection of antiganglioside autoantibodies in patients with autoimmune peripheral neuropathies

scientific article published on 01 August 2007

A novel automated indirect immunofluorescence autoantibody evaluation

scientific article published on 5 November 2011

A standardised FACS assay based on native, receptor transfected cells for the clinical diagnosis and monitoring of β1-adrenergic receptor autoantibodies in human heart disease

scientific article published on 01 April 2016

A strategy for cell-based multiplex diagnostics of Myasthenia gravis and autoimmune encephalitis by modifying the subcellular localization of cell membrane autoantigens

scientific article published in January 2014

Acute inflammatory neuropathy with monoclonal anti-GM2 IgM antibodies, IgM-κ paraprotein and additional autoimmune processes in association with a diffuse large B-cell non-Hodgkin's lymphoma

scientific article

Adhesion of Enteropathogenic, Enterotoxigenic, and Commensal Escherichia coli to the Major Zymogen Granule Membrane Glycoprotein 2

scientific article published in 2022

Adhesion of human and animal Escherichia coli strains in association with their virulence-associated genes and phylogenetic origins

scientific article published on 19 July 2013

Adhesion of to Pancreatic Secretory Granule Membrane Major Glycoprotein GP2 of Human and Porcine Origin Depends on FimH Sequence Variation

scientific article published on 22 August 2018

Adhesion patterns of commensal and pathogenic Escherichia coli from humans and wild animals on human and porcine epithelial cell lines.

scientific article published on 4 November 2013

Analysis of DNA Double-Strand Breaks and Cytotoxicity after 7 Tesla Magnetic Resonance Imaging of Isolated Human Lymphocytes

scientific article published on 15 July 2015

Analysis of Lymphocytic DNA Damage in Early Multiple Sclerosis by Automated Gamma-H2AX and 53BP1 Foci Detection: A Case Control Study

scientific article published on 28 January 2016

Analysis of three-dimensional biofilms on different material surfaces

scientific article published on 20 May 2020

Anti-hnRNP B1 (RA33) autoantibodies are associated with the clinical phenotype in Russian patients with rheumatoid arthritis and systemic sclerosis

scientific article

Anti-phospholipid IgG antibodies detected by line immunoassay differentiate patients with anti-phospholipid syndrome and other autoimmune diseases.

scientific article published on 29 May 2018

Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteins

scientific article published on 03 December 2021

Anti-thyroid peroxidase antibodies are associated with the absence of distant metastases in patients with newly diagnosed breast cancer

Antibodies against glycoprotein 2 are novel markers of intestinal inflammation in patients with an ileal pouch

scientific article published on 30 April 2013

Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers.

scientific article published on 21 May 2016

Antiphospholipid antibody profiling — Time for a new technical approach?

scientific article published on February 28, 2012

Antiphospholipid antibody profiling: association with the clinical phenotype of antiphospholipid syndrome? Comment on the article by Otomo et al

scientific article published on 01 August 2012

Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: lost and found

scientific article published on May 2012

Asialoglycoprotein receptor (ASGPR): a peculiar target of liver-specific autoimmunity.

scientific article published on 30 October 2012

Assessment of modulated cytostatic drug resistance by automated γH2AX analysis

scientific article published on 02 April 2015

Autoantibodies to GP2, the major zymogen granule membrane glycoprotein, are new markers in Crohn's disease

scientific article published on 31 December 2010

Autoantibodies to asialoglycoprotein receptor (ASGPR) in patients with autoimmune liver diseases.

scientific article published on 25 July 2015

Autoantibodies to asialoglycoprotein receptor (ASGPR) measured by a novel ELISA--revival of a disease-activity marker in autoimmune hepatitis

scientific article published on 2 July 2009

Autoantibody diagnostics in clinical practice

scientific article published on May 18, 2011

Autoantibody profiling in APS

scientific article published on 01 October 2014

Autoantibody testing by enzyme-linked immunosorbent assay-a case in which the solid phase decides on success and failure

scientific article published on 18 January 2020

Autoimmunity in Crohn's Disease-A Putative Stratification Factor of the Clinical Phenotype.

scientific article published on 30 June 2016

Automated Cell-Based Quantitation of 8-OHdG Damage

scientific article published on 5 April 2016

Automated evaluation of autoantibodies on human epithelial-2 cells as an approach to standardize cell-based immunofluorescence tests

scientific article

Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis.

scientific article published on 14 December 2012

Autoreactivity to isoforms of glycoprotein 2 in inflammatory bowel disease

scientific article published on 24 January 2015

Binding of natural human IgM auto-antibodies to human tumor cell lines and stimulated normal T lymphocytes

scientific article published in February 1994

Challenges of automated screening and differentiation of non-organ specific autoantibodies on HEp-2 cells.

scientific article published on 24 February 2009

Characterization of a B-CLL derived IgM-lambda antibody expressing typical features of a NPAB

scientific article published on 01 July 1994

Characterization of neutralizing anti-pre-S1 and anti-pre-S2 (HBV) monoclonal antibodies and their fragments

scientific article published in July 1999

Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers.

scientific article

Continuously increasing sensitivity over three generations of TSH receptor autoantibody assays

scientific article published on 05 October 2010

Correction: Simultaneous Automated Screening and Confirmatory Testing for Vasculitis-Specific ANCA.

scientific article published on 13 May 2015

Crohn's disease specific pancreatic antibodies: clinical and pathophysiological challenges

scientific article

Crohn's disease-specific pancreatic autoantibodies are specifically present in ruminants with paratuberculosis: implications for the pathogenesis of the human disease.

scientific article published on 2 May 2013

DNA damage assessment and potential applications in laboratory diagnostics and precision medicine

scholarly article published in April 2018

DNA double-strand breaks and micronuclei in human blood lymphocytes after repeated whole body exposures to 7T Magnetic Resonance Imaging

scientific article

DNA injury is acutely enhanced in response to increasing bulks of aerobic physical exercise.

scientific article published on 30 June 2016

Deoxyribonuclease activity of polyclonal IgGs: a putative serological marker in patients with spondyloarthritides.

scientific article published on July 2013

Diagnosis and classification of Crohn's disease.

scientific article published on 11 January 2014

Diagnosis and classification of ulcerative colitis

scientific article published on 11 January 2014

Diagnostic value, clinical utility and pathogenic significance of reactivity to the molecular targets of Crohn's disease specific-pancreatic autoantibodies.

scientific article published on 29 September 2011

Digital immunofluorescence enables automated detection of antinuclear antibody endpoint titers avoiding serial dilution

scientific article published in February 2014

Distinct Anti-IFI16 and Anti-GP2 Antibodies in Inflammatory Bowel Disease and Their Variation with Infliximab Therapy.

scientific article published on 15 September 2016

Evidence of Crohn's disease-related anti-glycoprotein 2 antibodies in patients with celiac disease

scientific article published on 01 August 2015

Expression of nicotinic acetylcholine receptor subunits in HEp-2 cells for immunodetection of autoantibody specificities in sera from Myasthenia gravis patients.

scientific article

Fully automated analysis of chemically induced γH2AX foci in human peripheral blood mononuclear cells by indirect immunofluorescence

scientific article published on 5 September 2013

Fully automated interpretation of ionizing radiation-induced γH2AX foci by the novel pattern recognition system AKLIDES®.

scientific article published on 26 March 2012

Generation and validation of murine monoclonal and camelid recombinant single domain antibodies specific for human pancreatic glycoprotein 2.

scientific article published on 7 April 2018

Genotypic and Phenotypic Characteristics Associated with Biofilm Formation by Human Clinical Escherichia coli Isolates of Different Pathotypes.

scientific article published on 6 October 2017

Genotyping of familial Mediterranean fever gene (MEFV)-Single nucleotide polymorphism-Comparison of Nanopore with conventional Sanger sequencing

scientific article published on 17 March 2022

Glycoprotein 2 antibodies in Crohn's disease.

scientific article

Glycoprotein 2 antibodies in inflammatory bowel disease: no association with disease phenotype?

scientific article published on 01 January 2013

Harmonization of antineutrophil cytoplasmic antibodies (ANCA) testing by reporting test result-specific likelihood ratios: position paper

scientific article published on 16 October 2020

High sensitive detection of double-stranded DNA antibodies by a modified Crithidia luciliae immunofluorescence test may improve diagnosis of systemic lupus erythematosus

scientific article published on 25 July 2010

High sensitive detection of double-stranded DNA autoantibodies by a modified Crithidia luciliae immunofluorescence test

scientific article published on 01 September 2009

High-sensitivity detection of autoantibodies against proteinase-3 by a novel third-generation enzyme-linked immunosorbent assay

scientific article published on 01 September 2009

Identification of Avian Pathogenic Escherichia coli's novel genes responsible for adhesion to chicken and human cell lines

scientific article published on 07 August 2020

Identification of GP2, the major zymogen granule membrane glycoprotein, as the autoantigen of pancreatic antibodies in Crohn's disease

scientific article published on 22 June 2009

Identification of pancreatic glycoprotein 2 as an endogenous immunomodulator of innate and adaptive immune responses.

scientific article published on 13 August 2012

IgA-gliadin antibodies, IgA-containing circulating immune complexes, and IgA glomerular deposits in wasting marmoset syndrome

scientific article published on 01 August 1999

Ileal inflammation may trigger the development of GP2-specific pancreatic autoantibodies in patients with Crohn's disease.

scientific article

Impact of in Vivo High-Field-Strength and Ultra-High-Field-Strength MR Imaging on DNA Double-Strand-Break Formation in Human Lymphocytes.

scientific article published on 30 September 2016

Improved removal of viruslike particles from purified monoclonal antibody IgM preparation via virus filtration

scientific article published in May 1996

Intestinal Escherichia coli colonization in a mallard duck population over four consecutive winter seasons

scientific article published on 12 February 2015

Loss and Gain of Tolerance to Pancreatic Glycoprotein 2 in Celiac Disease

scientific article published on 5 June 2015

Loss of tolerance to gut immunity protein, glycoprotein 2 (GP2) is associated with progressive disease course in primary sclerosing cholangitis.

scientific article published on 10 January 2018

Loss of tolerance to one or two major targets in Crohn's disease or just cross-reactivity?

scientific article published on 20 January 2013

M22 based (manual) ELISA for TSH-receptor antibody (TRAb) measurement is more sensitive than 2nd generation TRAb assays

scientific article published on 31 January 2009

Mobile phone radiofrequency exposure has no effect on DNA double strand breaks (DSB) in human lymphocytes.

scientific article published on July 2017

Multiplex assessment of non-organ-specific autoantibodies with a novel microbead-based immunoassay.

scientific article published on 3 January 2011

New platform technology for comprehensive serological diagnostics of autoimmune diseases

scientific article published on 19 December 2012

Next-Generation Autoantibody Testing by Combination of Screening and Confirmation-the CytoBead® Technology.

scientific article

Open source bioimage informatics tools for the analysis of DNA damage and associated biomarkers

scientific article published in 2019

Pancreatic-specific autoantibodies to glycoprotein 2 mirror disease location and behaviour in younger patients with Crohn's disease.

scientific article

Porcine E. coli: virulence-associated genes, resistance genes and adhesion and probiotic activity tested by a new screening method

scientific article

Profiling of rheumatoid arthritis associated autoantibodies.

scientific article

Real-time biospecific interaction analysis of a natural human polyreactive monoclonal IgM antibody and its Fab and scFv fragments with several antigens

scientific article published on 01 July 1994

Rediscovery of the Anti-Pancreatic Antibodies and Evaluation of their Prognostic Value in a Prospective Clinical Cohort of Crohn's Patients: The Importance of Specific Target Antigens [GP2 and CUZD1].

scientific article published on 12 May 2015

Reply to Dr. Pavlidis et al's letter

scientific article

Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing

scientific article published on 15 May 2015

Serologic Anti-GP2 Antibodies Are Associated with Genetic Polymorphisms, Fibrostenosis, and Need for Surgical Resection in Crohn's Disease

scientific article published on November 2016

Serological and viral genetic features of patients with COVID-19 in a selected German patient cohort-correlation with disease characteristics

scientific article published on 01 September 2021

Serological diagnosis and prognosis of severe acute pancreatitis by analysis of serum glycoprotein 2.

scientific article published on 12 November 2016

Simultaneous automated screening and confirmatory testing for vasculitis-specific ANCA.

scientific article

Simultaneous comprehensive multiplex autoantibody analysis for rapidly progressive glomerulonephritis

scientific article

Simultaneous detection of celiac disease-specific IgA antibodies and total IgA.

scientific article published on 30 January 2016

Solid-phase microbead array for multiplex O-serotyping of Escherichia coli

scientific article published in 2017

Species-specific and pathotype-specific binding of bacteria to zymogen granule membrane glycoprotein 2 (GP2).

scientific article published on 29 July 2014

Stable expression of human muscle-specific kinase in HEp-2 M4 cells for automatic immunofluorescence diagnostics of myasthenia gravis

scientific article published on 09 January 2014

Standardization of automated interpretation of immunofluorescence tests

scientific article published on 26 March 2013

Standardized detection of anti-ds DNA antibodies by indirect immunofluorescence - a new age for confirmatory tests in SLE diagnostics

scientific article published on 19 July 2011

TSH receptor antibody (TRAb) assays based on the human monoclonal autoantibody M22 are more sensitive than bovine TSH based assays

scientific article published on 14 October 2009

Technical problems arising from the use of the immunoblot for determination of the reactivity of natural antibodies with different lipopolysaccharides (LPS).

scientific article

The Novel Crohn's Disease Marker Anti-GP2 Antibody Is Associated with Ileocolonic Location of Disease.

scientific article published on 15 May 2013

The zymogen granule protein 2 (GP2) binds to scavenger receptor expressed on endothelial cells I (SREC-I)

scientific article published on December 8, 2010