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List of works by José Agundez

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Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process

scientific article
Cytochrome P450 gene polymorphism and cancer

scientific article published on June 2004
Interethnic and intraethnic variability of CYP2C8 and CYP2C9 polymorphisms in healthy individuals

scientific article (publication date: 2006)
Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism

scientific article published in October 1999
Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury.

scientific article published in August 2008
Polymorphisms of human N-acetyltransferases and cancer risk

scientific article
CYP3A4 variant alleles in white individuals with low CYP3A4 enzyme activity

scientific article published in March 2002
Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms

scientific article
Prevalence of CYP2D6 gene duplication and its repercussion on the oxidative phenotype in a white population

scientific article published on 01 March 1995
The effect of the cytochrome P450 CYP2C8 polymorphism on the disposition of (R)-ibuprofen enantiomer in healthy subjects.

scientific article published in January 2005
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting.

scientific article published on 19 October 2015
Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colorectal cancer

article
Clinical pharmacogenomic testing of KRAS, BRAF and EGFR mutations by high resolution melting analysis and ultra-deep pyrosequencing

scientific article
Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor

scientific article
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for CYP2C19 and Voriconazole Therapy.

scientific article published on 16 December 2016
Genetic predisposition to acute gastrointestinal bleeding after NSAIDs use

scientific article
Glutathione S-transferases mu 1, theta 1, pi 1, alpha 1 and mu 3 genetic polymorphisms and the risk of colorectal and gastric cancers in humans

scientific article published in July 2006
Mitochondrial superoxide dismutase and glutathione peroxidase in idiosyncratic drug-induced liver injury.

scientific article published in July 2010
Loss-of-function mutations in HPSE2 cause the autosomal recessive urofacial syndrome

scientific journal article
Characteristics of subjects experiencing hypersensitivity to non-steroidal anti-inflammatory drugs: patterns of response

scientific article published on 14 December 2010
Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline for CYP2D6 genotype and use of ondansetron and tropisetron

scientific article published on 21 December 2016
Pharmacokinetic Interaction of Fluvoxamine and Thioridazine in Schizophrenic Patients

scientific article published on 01 December 1999
Frequencies of 23 functionally significant variant alleles related with metabolism of antineoplastic drugs in the chilean population: comparison with caucasian and asian populations.

scientific article
Histamine pharmacogenomics.

scientific article published on May 2009
Detection of Genomic Variations in BRCA1 and BRCA2 Genes by Long-Range PCR and Next-Generation Sequencing

scientific article published on March 16, 2012
Pharmacogenomics in aspirin intolerance.

scientific article
Polymorphic drug metabolism in anaesthesia.

scientific article published on March 2009
Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: Is a combination of pharmacogenomics and metabolomics required to improve personalized medicine?

scientific article published on 01 June 2009
Analysis of midazolam and metabolites in plasma by high-performance liquid chromatography: probe of CYP3A.

scientific article published in June 1998
Impairment of rapid repetitive finger movements and visual reaction time in patients with essential tremor

scientific article published on 17 September 2009
Polymorphism of the TLR4 gene reduces the risk of hepatitis C virus-induced hepatocellular carcinoma

scientific article published on 26 January 2012
Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy

scientific article
Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease

scientific article
Vitamin D3 receptor ( VDR ) gene rs2228570 (Fok1) and rs731236 (Taq1) variants are not associated with the risk for multiple sclerosis: results of a new study and a meta-analysis

scientific article
LINGO1 and risk for essential tremor: results of a meta-analysis of rs9652490 and rs11856808.

scientific article published on 17 March 2012
Association between the oxidative polymorphism and early onset of Parkinson's disease

scientific article published on 01 March 1995
Genomic and pharmacogenomic biomarkers of Parkinson's disease.

scientific article published on February 2014
High frequency of mutations related to impaired CYP2C9 metabolism in a Caucasian population

scientific article published on 01 April 2001
The differential effect of NAT2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype

scientific article
Increased risk for hepatocellular carcinoma in NAT2-slow acetylators and CYP2D6-rapid metabolizers

scientific article published on 01 December 1996
Update on genetics of essential tremor.

scientific article published on 18 May 2013
Genetic variants of the arachidonic acid pathway in non-steroidal anti-inflammatory drug-induced acute urticaria

scientific article
Association of CYP2C9 genotypes leading to high enzyme activity and colorectal cancer risk

scientific article published in August 2001
Influence of vitamin D-related gene polymorphisms (CYP27B and VDR) on the response to interferon/ribavirin therapy in chronic hepatitis C

scientific article (publication date: 2013)
Gamma-aminobutyric acid GABRA4, GABRE, and GABRQ receptor polymorphisms and risk for essential tremor

scientific article published in July 2011
Vitamin D deficiency and vitamin D therapy in chronic hepatitis C.

scientific article published on March 2013
Gamma-aminobutyric acid (GABA) receptor rho (GABRR) polymorphisms and risk for essential tremor

scientific article published on 5 September 2010
Possible implications of doxycycline-rifampin interaction for treatment of brucellosis

scientific article published in December 1994
Cerebrospinal fluid biochemical studies in patients with Parkinson's disease: toward a potential search for biomarkers for this disease.

scientific article
Leflunomide-induced acute hepatitis

scientific article published in January 2004

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