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List of works by Anwar Anwar-Mohamed

20-Hydroxyeicosatetraenoic acid is a potential therapeutic target in cardiovascular diseases.

scientific article published on July 2013

A Refined Model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes.

scientific article published on 14 April 2014

A human ether-á-go-go-related (hERG) ion channel atomistic model generated by long supercomputer molecular dynamics simulations and its use in predicting drug cardiotoxicity.

scientific article published on 13 August 2014

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling

scientific article published on 18 February 2014

Acute arsenic treatment alters arachidonic acid and its associated metabolite levels in the brain of C57Bl/6 mice.

scientific article published on August 2014

Acute arsenic treatment alters cytochrome P450 expression and arachidonic acid metabolism in lung, liver and kidney of C57Bl/6 mice

scientific article published on 15 February 2013

Acute doxorubicin cardiotoxicity alters cardiac cytochrome P450 expression and arachidonic acid metabolism in rats

scientific article published on 29 September 2009

Acute doxorubicin toxicity differentially alters cytochrome P450 expression and arachidonic acid metabolism in rat kidney and liver.

scientific article

Alteration of cardiac cytochrome P450-mediated arachidonic acid metabolism in response to lipopolysaccharide-induced acute systemic inflammation

scientific article published on 4 January 2010

Arsenite down-regulates cytochrome P450 1A1 at the transcriptional and posttranslational levels in human HepG2 cells

scientific article published on 25 February 2010

Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct

scientific article published on 15 October 2011

Determination of the dominant arachidonic acid cytochrome p450 monooxygenases in rat heart, lung, kidney, and liver: protein expression and metabolite kinetics.

scientific article published on 10 November 2012

Differential modulation of aryl hydrocarbon receptor regulated enzymes by arsenite in the kidney, lung, and heart of C57BL/6 mice

scientific article published on 26 April 2012

Differential modulation of cytochrome P450 1a1 by arsenite in vivo and in vitro in C57BL/6 mice

scientific article published on 29 January 2013

Down-regulation of the carcinogen-metabolizing enzyme cytochrome P450 1a1 by vanadium.

scientific article

Down-regulation of the detoxifying enzyme NAD(P)H:quinone oxidoreductase 1 by vanadium in Hepa 1c1c7 cells

scientific article

Effect of mercury on aryl hydrocarbon receptor-regulated genes in the extrahepatic tissues of C57BL/6 mice.

scientific article published on 2 May 2012

Induction of cytochrome P450 1a1 by the food flavoring agent, maltol.

scientific article published on 15 January 2007

Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes

scientific article published on 8 December 2011

Mercury modulates the CYP1A1 at transcriptional and posttranslational levels in human hepatoma HepG2 cells

scientific article published on 15 September 2010

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

scientific article published on 24 October 2013

Modulation of NAD(P)H:quinone oxidoreductase by vanadium in human hepatoma HepG2 cells

scientific article published on 3 July 2010

Modulation of aryl hydrocarbon receptor-regulated genes by acute administration of ammonium metavanadate in kidney, lung and heart of C57BL/6 mice

scientific article published on 18 May 2012

Modulation of cytochrome P450 1 (Cyp1) by vanadium in hepatic tissue and isolated hepatocyte of C57BL/6 mice.

scientific article published on 20 February 2013

Murine atrial HL-1 cell line is a reliable model to study drug metabolizing enzymes in the heart.

scientific article

Posttranslational mechanisms modulating the expression of the cytochrome P450 1A1 gene by methylmercury in HepG2 cells: a role of heme oxygenase-1.

scientific article published on 26 March 2013

Secondary cytotoxicity mediated by alveolar macrophages: a contribution to the total efficacy of nanoparticles in lung cancer therapy?

scientific article

Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells.

scientific article

The effect of Nrf2 knockout on the constitutive expression of drug metabolizing enzymes and transporters in C57Bl/6 mice livers.

scientific article published on 31 January 2011

The p38 MAPK inhibitor SB203580 induces cytochrome P450 1A1 gene expression in murine and human hepatoma cell lines through ligand-dependent aryl hydrocarbon receptor activation

scientific article published on 27 July 2011

Transcriptional and posttranscriptional regulation of CYP1A1 by vanadium in human hepatoma HepG2 cells

scientific article published on 11 March 2010

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