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List of works by Philippe Georgel

A mouse model of MSU-induced acute inflammation in vivo suggests imiquimod-dependent targeting of Il-1β as relevant therapy for gout patients

scientific article published on 12 January 2020

A novel homeobox nkch4 gene from the Drosophila 93E region.

scientific article published on May 1993

A toll-like receptor 2-responsive lipid effector pathway protects mammals against skin infections with gram-positive bacteria

scientific journal article

An unusually high substitution rate in transplant-associated BK polyomavirus in vivo is further concentrated in HLA-C-bound viral peptides

scientific article published on 18 October 2018

Analysis of the MCMV resistome by ENU mutagenesis

scientific article published in May 2006

Anti-inflammatory effect of active nanofibrous polymeric membrane bearing nanocontainers of atorvastatin complexes

scientific article published on 2 November 2017

BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo

scientific article published in Scientific Reports

Back to the future: bacteriophages as promising therapeutic tools

scientific article published on 19 February 2016

CCR6 controls autoimmune but not innate immunity-driven experimental arthritis

scientific article published on 22 August 2018

CD14 is required for MyD88-independent LPS signaling.

scientific article published on 15 May 2005

CD36 is a sensor of diacylglycerides

scientific journal article

Cell-associated double-stranded RNA enhances antitumor activity through the production of type I IFN.

scientific article published in November 2006

Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice

scientific article published on 21 January 2020

Circulating Human Eosinophils Share a Similar Transcriptional Profile in Asthma and Other Hypereosinophilic Disorders

scientific article published on 2 November 2015

DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging.

scientific article published on 24 July 2018

Delivery of miR-146a to Ly6C Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

scientific article published on 13 November 2018

Deregulation of type I IFN-dependent genes correlates with increased susceptibility to cytomegalovirus acute infection of dicer mutant mice

scientific article (publication date: 2012)

Dermatomyositis flare on imiquimod therapy highlights a crucial role of aberrant TLR7 signalling.

scientific article published on 31 October 2016

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

scientific article

Differentiation of follicular helper T cells by salivary gland epithelial cells in primary Sjögren's syndrome.

scientific article published on 9 January 2014

Dorsal-B, a splice variant of the Drosophila factor Dorsal, is a novel Rel/NF-kappaB transcriptional activator

scientific article published on March 1999

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis

scientific article published in October 2001

Drosophila immunity. A sequence homologous to mammalian interferon consensus response element enhances the activity of the diptericin promoter

scientific article

ENU mutagenesis in mice

scientific article published in January 2008

ENU-induced phenovariance in mice: inferences from 587 mutations

scientific article

Expansion and function of CD8+ T cells expressing Ly49 inhibitory receptors specific for MHC class I molecules

scientific article published in September 2004

Expression and nuclear translocation of the rel/NF-kappa B-related morphogen dorsal during the immune response of Drosophila.

scientific article published in October 1993

Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila.

scientific article published on February 1995

GEBF-I activates the Drosophila Sgs3 gene enhancer by altering a positioned nucleosomal core particle

scientific article published on 01 November 1993

GEBF-I in Drosophila species and hybrids: the co-evolution of an enhancer and its cognate factor

scientific article published in October 1992

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

scientific article

Genetic analysis of innate immunity

scientific article published on January 2006

Genetic analysis of innate immunity: TIR adapter proteins in innate and adaptive immune responses

scientific article

Genetic analysis of innate resistance to mouse cytomegalovirus (MCMV).

scientific article

Genetic dissection of innate immunity to infection: the mouse cytomegalovirus model

scientific article

High diversity of MIC genes in non-human primates.

scientific article

Homozygosity for the V377I mutation in mevalonate kinase causes distinct clinical phenotypes in two sibs with hyperimmunoglobulinaemia D and periodic fever syndrome (HIDS)

scientific article published on 7 March 2016

Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression

scientific journal article

Identification of Mouse Cytomegalovirus Resistance Loci by ENU Mutagenesis ⬇️

scientific article published on October 20, 2009

Increased Viral Dissemination in the Brain and Lethality in MCMV-Infected, Dicer-Deficient Neonates

scientific article published on 6 May 2015

Innate immune receptors in solid organ transplantation

scientific article published on 5 April 2016

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements.

scientific article published on December 1993

Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome

scientific article published on 11 June 2015

Lps2 and signal transduction in sepsis: at the intersection of host responses to bacteria and viruses

scientific article published on January 2003

MiR-20a regulates ASK1 expression and TLR4-dependent cytokine release in rheumatoid fibroblast-like synoviocytes

scientific article published on 20 October 2012

MiR-30a-3p negatively regulates BAFF synthesis in systemic sclerosis and rheumatoid arthritis fibroblasts

scientific article

MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.

scientific article published on 22 May 2017

Multi-OMICS analyses unveil STAT1 as a potential modifier gene in mevalonate kinase deficiency

scientific article published on 20 July 2018

Polymorphisms in EGFR and IL28B are associated with spontaneous clearance in an HCV-infected Iranian population.

scientific article published on 17 September 2015

Protein kinase D at the Golgi controls NLRP3 inflammasome activation.

scientific article published on 17 July 2017

R-form LPS, the master key to the activation ofTLR4/MD-2-positive cells

scientific article published in March 2006

Reduced DICER1 Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli.

scientific article published in August 2016

Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells

scientific article

TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes.

scientific article published on 21 November 2011

TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages.

scientific article published on 12 March 2008

Temporomandibular joint damage in K/BxN arthritic mice

scientific article published on 06 February 2020

The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

scientific article published in November 2002

The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9

scientific article

The heterogeneous allelic repertoire of human toll-like receptor (TLR) genes

scientific article

The miR-17 ∼ 92 Cluster: A Key Player in the Control of Inflammation during Rheumatoid Arthritis.

scientific article published on 19 March 2013

The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice

scientific article

The nonsense allele oblivious reveals a sensor of di-acylglycerides acting in conjunction with TLR2 and TLR6.

scientific article published on 13 September 2004

Therapeutic Modulation of Plasmacytoid Dendritic Cells in Experimental Arthritis.

scientific article published on 4 August 2017

Therapeutic Perspectives for Interferons and Plasmacytoid Dendritic Cells in Rheumatoid Arthritis.

scientific article published on 5 March 2018

Toll-dependent and toll-independent innate antiviral immunity

scientific article published in November 2006

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

scientific article

Use of in vivo imaging to monitor the progression of experimental mouse cytomegalovirus infection in neonates.

scientific article

Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway

scientific article published on 12 February 2007

Virus-host interactions in hepatitis C virus infection: implications for molecular pathogenesis and antiviral strategies.

scientific article published on 25 May 2010

Zinc-Alpha-2-Glycoprotein in Inflammatory Bowel Disease

scientific article published on 01 April 2018

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