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List of works by Michael Robert Edwards

"Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways." C.A. Hewson, J.J. Haas, N.W. Bartlett, S.D. Message, V. Laza-Stanca, T. Kebadze, G. Caramori, J. Zhu, M.R. Edbrooke, L.A. Stanciu, O.M. Kon, A. Papi, P.K

Anti-viral agents: potential utility in exacerbations of asthma

scientific article

Azithromycin induces anti-viral responses in bronchial epithelial cells

scientific article published on 11 February 2010

CXC chemokines and antimicrobial peptides in rhinovirus-induced experimental asthma exacerbations.

scientific article

Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium

scientific article

Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells.

scientific article

Corticosteroids and beta2 agonists differentially regulate rhinovirus-induced interleukin-6 via distinct Cis-acting elements

scientific article published on 29 March 2007

Deficient interferon in virus-induced asthma exacerbations.

scientific article published on 17 July 2008

Defining critical roles for NF-κB p65 and type I interferon in innate immunity to rhinovirus.

scientific article

Experimental rhinovirus infection as a human model of chronic obstructive pulmonary disease exacerbation

scientific article

IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection

scientific article

IL-1beta induces IL-8 in bronchial cells via NF-kappaB and NF-IL6 transcription factors and can be suppressed by glucocorticoids.

scientific article published on 17 March 2005

Immunoglobulin gene rearrangement, repertoire diversity, and the allergic response.

scientific article published on November 2003

Impaired innate interferon induction in severe therapy resistant atopic asthmatic children

scientific article published on 05 December 2012

Impaired type I and type III interferon induction and rhinovirus control in human cystic fibrosis airway epithelial cells

scientific article published on 02 January 2012

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

scientific article

Interferon-lambda as a new approach for treatment of allergic asthma?

scientific article

Lack of an exaggerated inflammatory response on virus infection in cystic fibrosis.

scientific article published on 30 June 2011

Mechanisms of adverse effects of {beta}-agonists in asthma

scientific article published in September 2009

Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation

scientific article

New treatment regimes for virus-induced exacerbations of asthma

scientific article

Obesity and susceptibility to severe outcomes following respiratory viral infection

scientific article

Pathogen sensing pathways in human embryonic stem cell derived-endothelial cells: role of NOD1 receptors

scientific article

Protein kinase R, IkappaB kinase-beta and NF-kappaB are required for human rhinovirus induced pro-inflammatory cytokine production in bronchial epithelial cells

scientific article published on 20 September 2006

RSV infection modulates IL-15 production and MICA levels in respiratory epithelial cells.

scientific article

RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity

scientific article

Retinoic acid-inducible gene I-inducible miR-23b inhibits infections by minor group rhinoviruses through down-regulation of the very low density lipoprotein receptor

scientific article

Rhinovirus 16-induced IFN-α and IFN-β are deficient in bronchoalveolar lavage cells in asthmatic patients.

scientific article

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-κB and EGFR pathways.

scientific article

Rhinovirus replication in human macrophages induces NF-kappaB-dependent tumor necrosis factor alpha production

scientific article

Rhinovirus-induced interferon production is not deficient in well controlled asthma

scientific article published on 14 October 2013

Role of deficient type III interferon-λ production in asthma exacerbations

article

Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection

scientific article

Role of xanthine oxidase activation and reduced glutathione depletion in rhinovirus induction of inflammation in respiratory epithelial cells.

scientific article published on 04 August 2008

Signalling pathways mediating type I interferon gene expression.

scientific article published on July 2007

Structural analysis of the ErbB-2 receptor using monoclonal antibodies: Implications for receptor signalling

scientific article

TLR3, TLR4 and TLRs7-9 Induced Interferons Are Not Impaired in Airway and Blood Cells in Well Controlled Asthma

scientific article

Targeting the NF-kappaB pathway in asthma and chronic obstructive pulmonary disease.

scientific article published on 06 October 2008

The airway epithelium: soldier in the fight against respiratory viruses

scientific article

The application of phage display in allergy research: characterization of IgE, identification of allergens and development of novel therapeutics

scientific article

The effectiveness of different rat IgG subclasses as IgE-blocking antibodies in the rat basophil leukaemia cell model

scientific article published on 01 April 1999

The microbiology of asthma

scientific article published on 06 June 2012

The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations

scientific article

The role of macrolides in asthma: current evidence and future directions

scientific article

Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells

scientific article

Valency or wählency: is the epitope diversity of the B-cell response regulated or chemically determined?

scientific article published on 01 October 2001

Viral Toll Like Receptor activation of pulmonary vascular smooth muscle cells results in endothelin-1 generation; relevance to pathogenesis of pulmonary arterial hypertension

scientific article published on 28 August 2012