Search filters

Authors whose works are in public domain in at least one jurisdiction

List of works by Félix Carvalho

"Ecstasy" toxicity to adolescent rats following an acute low binge dose

scientific article

"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.

scientific article

2-styrylchromones as novel inhibitors of xanthine oxidase. A structure-activity study

scientific article published in February 2002

5,7-Dihydroxitryptamine toxicity to serotonergic neurons in serum free raphe cultures

scientific article published on 26 April 2008

A Safe and Stable Neonatal Vaccine Targeting GAPDH Confers Protection against Group B Streptococcus Infections in Adult Susceptible Mice

scientific article published on 16 December 2015

A breakthrough on Amanita phalloides poisoning: an effective antidotal effect by polymyxin B.

scientific article published on 18 September 2015

A cocaine body packer case report: clinical and forensic aspects.

scientific article published in July 2009

A mild cumulative dose of mitoxantrone leads to age-dependent cardiac injury in mice

scholarly article by J. Dores-Sousa et al published October 2015 in Toxicology Letters

Acetaminophen prevents oxidative burst and delays apoptosis in human neutrophils

scientific article published on 18 March 2013

Acetyl-L-carnitine provides effective in vivo neuroprotection over 3,4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain.

scientific article published on 30 October 2008

Active and peripheral anionic sites of acetylcholinesterase have differential modulation effects on cell proliferation, adhesion and neuritogenesis in the NG108-15 cell line

scientific article published on 27 March 2014

Acute Paraquat Poisoning

scientific article published on 01 July 2006

Acute administration of tramadol and tapentadol at effective analgesic and maximum tolerated doses causes hepato- and nephrotoxic effects in Wistar rats.

scientific article published on 6 July 2017

Acute toxicity of widely used pharmaceuticals in aquatic species: Gambusia holbrooki, Artemia parthenogenetica and Tetraselmis chuii

scientific article published in July 2005

Adaptative response of antioxidant enzymes in different areas of rat brain after repeated d-amphetamine administration

scientific article published in July 2001

Administration of tourniquet. I. Are edema and oxidative stress related to each other and to the duration of ischemia in reperfused skeletal muscle?

scientific article published on 01 January 1997

Adrenaline and reactive oxygen species elicit proteome and energetic metabolism modifications in freshly isolated rat cardiomyocytes

scientific article

Adrenaline in pro-oxidant conditions elicits intracellular survival pathways in isolated rat cardiomyocytes

scientific article published on 24 December 2008

Adverse outcome pathways induced by 3,4-dimethylmethcathinone and 4-methylmethcathinone in differentiated human SH-SY5Y neuronal cells

scientific article published on 07 May 2020

Aged rats are more vulnerable than adolescents to “ecstasy”-induced toxicity

article

Amanita phalloides poisoning: Mechanisms of toxicity and treatment

scientific article published on 12 September 2015

An effective antidotal combination of polymyxin B and methylprednisolone for α-amanitin intoxication

scientific article published on 19 March 2019

An effective antidote for paraquat poisonings: the treatment with lysine acetylsalicylate

scientific article published on 6 November 2008

Analytical investigation of legal high products containing Salvia divinorum traded in smartshops and internet

scientific article published on 19 July 2014

Antioxidant activity of Centaurium erythraea infusion evidenced by its superoxide radical scavenging and xanthine oxidase inhibitory activity

scientific article (publication date: July 2001)

Antioxidant activity of Hypericum androsaemum infusion: scavenging activity against superoxide radical, hydroxyl radical and hypochlorous acid ⬇️

scientific article published in October 2002

Antioxidant and pro-oxidant activities of carotenoids and their oxidation products

scientific article published on 02 August 2018

Antioxidant properties and associated mechanisms of salicylates.

scientific article published on January 2011

Antioxidative properties of cardoon (Cynara cardunculus L.) infusion against superoxide radical, hydroxyl radical, and hypochlorous acid

scientific article published in August 2002

Behaviour and biomarkers of oxidative stress in Gambusia holbrooki after acute exposure to widely used pharmaceuticals and a detergent

scientific article

Benzo fury: A new trend in the drug misuse scene

scientific article published on 05 February 2019

Biodistribution and metabolic profile of 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats through gas chromatography-mass spectrometry (GC-MS) analysis

scientific article published on 18 October 2019

Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity

scientific article

Bruxism after 3,4-methylenedioxymethamphetamine (ecstasy) abuse

scientific article published in June 2010

Burden of injury along the development spectrum: associations between the Socio-demographic Index and disability-adjusted life year estimates from the Global Burden of Disease Study 2017

scientific article published on 08 January 2020

CARDIOTOXICITY STUDIES USING FRESHLY ISOLATED CALCIUM-TOLERANT CARDIOMYOCYTES FROM ADULT RAT

scientific article published on 01 January 2001

CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA)

scientific article

Calcium Pathways in Human Neutrophils-The Extended Effects of Thapsigargin and ML-9

scientific article published on 09 November 2018

Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.

scientific article published on 8 April 2017

Changes in taurine levels in response to repeated administration of the beta2-agonist salbutamol in lambs

scientific article published on 01 February 1997

Characterization and use of the total head soluble cholinesterases from mosquitofish (Gambusia holbrooki) for screening of anticholinesterase activity.

scientific article

Cholinesterase from the common prawn (Palaemon serratus) eyes: catalytic properties and sensitivity to organophosphate and carbamate compounds.

scientific article published on 23 February 2006

Chronic green tea consumption prevents age-related changes in rat hippocampal formation.

scientific article published on 2 May 2009

Clinical and forensic signs related to chemical burns: a mechanistic approach

scientific article published on October 2014

Clinical and forensic signs related to cocaine abuse.

scientific article published on March 2012

Clinical and forensic signs related to ethanol abuse: a mechanistic approach

scientific article published on February 2014

Clinicopathological significance of immunoexpression of claudin-1 and claudin-7 in feline mammary carcinomas

scientific article published on 20 September 2014

Co-ingestion of amatoxins and isoxazoles-containing mushrooms and successful treatment: A case report

scientific article published on 16 June 2015

Cocaine-induced kidney toxicity: an in vitro study using primary cultured human proximal tubular epithelial cells

scientific article published on 8 October 2011

Collection of biological samples in forensic toxicology.

scientific article published on September 2010

Combining CXCR4-targeted and nontargeted nanoparticles for effective unassisted in vitro magnetic hyperthermia.

scientific article published on 5 February 2018

Comparative effects of 3,4-methylenedioxymethamphetamine and 4-methylthioamphetamine on rat liver mitochondrial function.

scientific article published on 6 February 2010

Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.

scientific article published on 16 December 2003

Comparative metabolism of tramadol and tapentadol: a toxicological perspective.

scientific article

Comparative pharmacology and toxicology of tramadol and tapentadol.

scientific article published on 25 January 2018

Comparative study of the neurotoxicological effects of tramadol and tapentadol in SH-SY5Y cells

scientific article published on 14 June 2016

Contractile effects of 3,4-methylenedioxymethamphetamine on the human internal mammary artery

scientific article published on 11 April 2016

Copper enhances isoproterenol toxicity in isolated rat cardiomyocytes: effects on oxidative stress

scientific article

Correction to: In vitro mechanistic studies on α-amanitin and its putative antidotes

scientific article published on 17 April 2020

Correction: Profiling of RNA Degradation for Estimation of Post Mortem Interval

scientific article published on 18 June 2013

Cytotoxicity and cell signalling induced by continuous mild hyperthermia in freshly isolated mouse hepatocytes

scientific article published on 27 April 2006

D-amphetamine-induced hydrogen peroxide production in skeletal muscle is modulated by monoamine oxidase inhibition

scientific article published in August 2004

Data analysis of "krokodil" samples obtained by street-like synthesis.

scientific article

Decreasing the toxicity of paraquat through the complexation with sodium salicylate: Stoichiometric analysis.

scientific article published on 19 August 2015

Depletion of total non-protein sulphydryl groups in mouse tissues after administration of d-amphetamine

scientific article published on 01 October 1993

Determination of amatoxins and phallotoxins in Amanita phalloides mushrooms from northeastern Portugal by HPLC-DAD-MS.

scientific article published on 24 April 2015

Determination of amphetamine and its metabolite p-hydroxyamphetamine in rat urine by reversed-phase high-performance liquid chromatography after dabsyl derivatization.

scientific article

Development and validation of a GC/IT-MS method for simultaneous quantitation of para and meta-synephrine in biological samples

scientific article published on 23 February 2010

Development of novel rifampicin-derived P-glycoprotein activators/inducers. synthesis, in silico analysis and application in the RBE4 cell model, using paraquat as substrate

scientific article (publication date: 2013)

Differential Effects of Methyl-4-Phenylpyridinium Ion, Rotenone, and Paraquat on Differentiated SH-SY5Y Cells

scientific article published on 20 March 2013

Do invading leucocytes contribute to the decrease in glutathione concentrations indicating oxidative stress in exercised muscle, or are they important for its recovery?

scientific article published on 01 January 1994

Do metals inhibit acetylcholinesterase (AChE)? Implementation of assay conditions for the use of AChE activity as a biomarker of metal toxicity

scientific article published in September 2005

Does mercury interact with the inhibitory effect of dichlorvos on Palaemon serratus (Crustacea: Decapoda) cholinesterase?

scientific article published on 17 July 2008

Downgrading the systemic condition of rabbits after long term exposure to cypermethrin and piperonyl butoxide.

scientific article published on 12 December 2015

Doxorubicin Is Key for the Cardiotoxicity of FAC (5-Fluorouracil + Adriamycin + Cyclophosphamide) Combination in Differentiated H9c2 Cells

scientific article published on 10 January 2019

Doxorubicin induces biphasic neurotoxicity to rat cortical neurons

scientific article published on 31 December 2007

Dual effect of red wine on liver redox status: a concise and mechanistic review

scientific article published on 31 May 2015

ER stress-inducible factor CHOP affects the expression of hepcidin by modulating C/EBPalpha activity

scientific article

Ecstasy induces apoptosis via 5-HT(2A)-receptor stimulation in cortical neurons

scientific article published on 27 April 2007

Ecstasy-induced cell death in cortical neuronal cultures is serotonin 2A-receptor-dependent and potentiated under hyperthermia

scientific journal article

Ecstasy-induced oxidative stress to adolescent rat brain mitochondria in vivo: influence of monoamine oxidase type A.

scientific article

Effect of 3,4-methylenedioxyamphetamine on dendritic spine dynamics in rat neocortical neurons--involvement of heat shock protein 27.

scientific article

Effect of 3,4-methylenedioxymethamphetamine ("ecstasy") on body temperature and liver antioxidant status in mice: influence of ambient temperature

scientific article published in March 2002

Effect of chronic ethanol exposure on the hepatotoxicity of ecstasy in mice: an ex vivo study.

scientific article

Effect of d -amphetamine repeated administration on rat antioxidant defences

scientific article published on 01 March 1999

Effect of physical exercise on markers of acute cardiotoxicity induced by d-amphetamine in an animal model

scientific article published on 01 November 2006

Effect of treatment with beta-agonists on tissue and urinary taurine levels in rats. Mechanism and implications for protection

scientific article published on 01 January 1996

Effective analgesic doses of tramadol or tapentadol induce brain, lung and heart toxicity in Wistar rats.

scientific article published on 9 May 2017

Effects of 3,4-methylenedioxymethamphetamine administration on retinal physiology in the rat

scientific article

Effects of multi-stressors on juveniles of the marine fish Pomatoschistus microps: Gold nanoparticles, microplastics and temperature.

scientific article published on 28 November 2015

Effects of widely used pharmaceuticals and a detergent on oxidative stress biomarkers of the crustacean Artemia parthenogenetica.

scientific article published on 19 August 2005

Electrically-evoked release of taurine in the rat vas deferens: evidence for a purinoceptor-mediated effect

article

Electrospray tandem mass spectrometry of aminochromes

scientific article published in January 2001

Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models

scientific article published on 14 December 2019

Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study

scientific article published on 18 December 2019

Erythropoietin mediates hepcidin expression in hepatocytes through EPOR signaling and regulation of C/EBPalpha

scientific article published on 07 March 2008

Ethanol addictively enhances the in vitro cardiotoxicity of cocaine through oxidative damage, energetic deregulation, and apoptosis

scientific article published on 30 May 2018

Ethical, technical and legal procedures of the medical doctor responsibility to accomplish the road enforcement law about driving under the influence of alcohol and psychotropic substances

scientific article published on November 2010

Evaluation of GSH adducts of adrenaline in biological samples

scientific article published in July 2007

Evaluation of toxic/protective effects of the essential oil of Salvia officinalis on freshly isolated rat hepatocytes

scientific article

Fatal Intoxications in the North of Portugal: 12 Years of Retrospective Analysis

scientific article published on 24 July 2016

Flavonoids as antiobesity agents: A review

scientific article published on 20 October 2020

Flavonoids with an oligopolysulfated moiety: a new class of anticoagulant agents.

scientific article published on 7 December 2010

Fosfomycin increases chromosome instability in lymphocytes from Fanconi Anemia patients

scientific article published on 25 April 2013

Full survival of paraquat-exposed rats after treatment with sodium salicylate☆

scientific article published on 08 January 2007

Gas chromatography-ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine

scientific article published on 4 February 2010

Genetic profile and cancer-related pain: a tale from two outlier cases with bone metastatic disease.

scientific article

Global Mortality From Firearms, 1990-2016

scientific article published in The Journal of the American Medical Association

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017: A Systematic Analysis for the Global Burden of Disease Study

scientific article published on 27 September 2019

Green tea averts age-dependent decline of hippocampal signaling systems related to antioxidant defenses and survival

scientific article published on 11 January 2010

Haematological toxicity of clozapine and some other drugs used in psychiatry.

scientific article published on 17 March 2011

Hair as an alternative matrix in bioanalysis

scientific article published on April 2013

Hepatic Metabolic Derangements Triggered by Hyperthermia: An In Vitro Metabolomic Study

scientific article published on 15 October 2019

Hepatoprotective activity of xanthones and xanthonolignoids against tert-butylhydroperoxide-induced toxicity in isolated rat hepatocytes--comparison with silybin

scientific article published on 01 November 1995

Hepatotoxicity of 3,4-methylenedioxyamphetamine and alpha-methyldopamine in isolated rat hepatocytes: formation of glutathione conjugates

scientific article published on 28 October 2003

Hepcidin messenger RNA expression in human lymphocytes

scientific article

Human and experimental toxicology of diquat poisoning: Toxicokinetics, mechanisms of toxicity, clinical features, and treatment

scientific article

Human and experimental toxicology of orellanine.

scientific article

Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition.

scientific article published in October 2001

Hydroxyl radical and hypochlorous acid scavenging activity of small centaury (Centaurium erythraea) infusion. A comparative study with green tea (Camellia sinensis).

scientific article published in January 2003

Hyperthermia Severely Affects the Vascular Effects of MDMA and Metabolites in the Human Internal Mammary Artery In Vitro.

scientific article published in October 2017

Identification of 4-methylthioamphetamine and some of its metabolites in mouse urine by GC-MS after acute administration.

scientific article

Immunomodulatory effects of flavonoids in the prophylaxis and treatment of inflammatory bowel diseases: a comprehensive review

scientific article published on 14 February 2018

Improvement of genetic stability in lymphocytes from Fanconi anemia patients through the combined effect of α-lipoic acid and N-acetylcysteine

scientific article

In vitro hepatotoxicity of 'Legal X': the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis.

scientific article published on 29 June 2016

In vitro mechanistic studies on α-amanitin and its putative antidotes

scientific article published on 19 March 2020

In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells ⬇️

scientific article published on September 21, 2010

In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)

scientific article published on 19 November 2020

Increased red cell distribution width in Fanconi anemia: a novel marker of stress erythropoiesis.

scientific article

Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity

scientific article published on November 2006

Inhibition of Glutathione Reductase by Isoproterenol Oxidation Products

scientific article published on 01 November 1999

Inhibition of glutathione reductase by isoproterenol oxidation products

scientific article published on 01 January 2000

Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study

scientific article published on 21 November 2017

Interaction of polyacrylic acid coated and non-coated iron oxide nanoparticles with human neutrophils.

scientific article published on 26 November 2013

Interleukin-1β genotype and circulating levels in cancer patients: metastatic status and pain perception.

scientific article published on 18 April 2014

Kinetics of paraquat in the isolated rat lung: Influence of sodium depletion

scientific article published on 01 August 2006

Leucoisoprenochrome-o-semiquinone formation in freshly isolated adult rat cardiomyocytes

scientific article published in December 2004

Long-term exposure to cypermethrin and piperonyl butoxide cause liver and kidney inflammation and induce genotoxicity in New Zealand white male rabbits.

scientific article published on 16 June 2016

Long-term survival of paraquat intoxicated rats following treatment with sodium salicylate: A multitarget protection analysis

Lysine acetylsalicylate improves the safety of paraquat formulation in rats by increasing its elimination and preventing lung and kidney injury

Lysine acetylsalicylate increases the safety of a paraquat formulation to freshwater primary producers: a case study with the microalga Chlorella vulgaris.

scientific article published on 7 November 2013

MDMA impairs mitochondrial neuronal trafficking in a Tau- and Mitofusin2/Drp1-dependent manner.

scientific article published on 13 February 2014

MDMA modulates 5-HT1-mediated contractile response of the human internal thoracic artery in vitro

scientific article published on 15 November 2018

Magnetic Hyperthermia for Cancer Treatment: Main Parameters Affecting the Outcome of In Vitro and In Vivo Studies

scientific article published on 22 June 2020

Mechanisms of P-gp inhibition and effects on membrane fluidity of a new rifampicin derivative, 1,8-dibenzoyl-rifampicin.

scientific article published on 16 May 2013

Mechanisms of cholinesterase inhibition by inorganic mercury

scientific article

Mechanisms underlying the hepatotoxic effects of ecstasy

scientific article published on August 2010

Metabolic interactions between ethanol and MDMA in primary cultured rat hepatocytes.

scientific article published on 17 February 2010

Metabolic signature of methylone in primary mouse hepatocytes, at subtoxic concentrations

scientific article published on 07 September 2019

Metabolism is required for the expression of ecstasy-induced cardiotoxicity in vitro

scientific article

Metabolism of the designer drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in mice, after acute administration

scientific article published in November 2004

Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes.

scientific article

Metabolomic approaches in the discovery of potential urinary biomarkers of drug-induced liver injury (DILI).

scientific article

Methods for the analysis of transcriptome dynamics

scientific article published on 26 July 2019

Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of β-keto amphetamines-related neurotoxicity.

scientific article

Methylphenidate clinically oral doses improved brain and heart glutathione redox status and evoked renal and cardiac tissue injury in rats

scientific article published on 23 February 2018

Methylphenidate effects in the young brain: friend or foe?

scientific article published on 12 April 2017

Mitochondria: key players in the neurotoxic effects of amphetamines.

scientific article published on 6 March 2015

Mitoxantrone impairs proteasome activity and prompts early energetic and proteomic changes in HL-1 cardiomyocytes at clinically relevant concentrations

scientific article published on 07 September 2020

Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A 'Chemobrain' In Vitro Study.

scientific article published on 5 May 2018

Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations

scientific article

Modeling chronic brain exposure to amphetamines using primary rat neuronal cortical cultures.

scientific article published on 15 July 2014

Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy.

scientific article

Modulation of rat cerebellum oxidative status by prolonged red wine consumption

scientific article published on 11 April 2008

Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview.

scientific article

Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis

scientific article published on 05 June 2020

Monoamine Oxidase-B Mediates Ecstasy-Induced Neurotoxic Effects to Adolescent Rat Brain Mitochondria

scientific article published on 01 September 2007

Morphine glucuronidation increases its analgesic effect in guinea pigs.

scientific article published on 24 June 2014

N-acetyl-cysteine prevents the cytotoxicity of adrenaline oxidation in SH-SY5Y cells

Naphthoquinoxaline metabolite of mitoxantrone is less cardiotoxic than the parent compound and it can be a more cardiosafe drug in anticancer therapy

scientific article published on 14 September 2016

Neuronal nitric oxide synthase is a key factor in doxorubicin-induced toxicity to rat-isolated cortical neurons

scientific article published on 19 November 2009

Neuropeptide Y protects retinal neural cells against cell death induced by ecstasy.

scientific article

Neurotoxicity mechanisms of thioether ecstasy metabolites

scientific article published on 30 April 2007

Neurotoxicity of "ecstasy" and its metabolites in human dopaminergic differentiated SH-SY5Y cells

scientific article published on 27 November 2012

New formulation of paraquat with lysine acetylsalicylate with low mammalian toxicity and effective herbicidal activity

article

New in silico insights into the inhibition of RNAP II by α-amanitin and the protective effect mediated by effective antidotes

scientific article

Non-targeted and targeted analysis of wild toxic and edible mushrooms using gas chromatography-ion trap mass spectrometry

scientific article published on 10 October 2013

Opioids in the Frame of New Psychoactive Substances Network: A Complex Pharmacological and Toxicological Issue

scientific article published on 4 July 2017

P-glycoprotein induction as a cellular protection tool against xenobiotics toxicity

P-glycoprotein induction: an antidotal pathway for paraquat-induced lung toxicity

article

Paraquat research: do recent advances in limiting its toxicity make its use safer?

scientific article published on January 2013

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases--a mechanistic approach

scientific article published on 03 February 2014

Pixantrone, a new anticancer drug with the same old cardiac problems? An in vitro study with differentiated and non-differentiated H9c2 cells

scientific article published on 01 May 2018

Polyacrylic acid coated and non-coated iron oxide nanoparticles are not genotoxic to human T lymphocytes

scientific article published on 12 February 2015

Polyacrylic acid-coated and non-coated iron oxide nanoparticles induce cytokine activation in human blood cells through TAK1, p38 MAPK and JNK pro-inflammatory pathways.

scientific article

Polysulfated xanthones: multipathway development of a new generation of dual anticoagulant/antiplatelet agents.

scientific article published on 18 July 2011

Postmortem analyses unveil the poor efficacy of decontamination, anti-inflammatory and immunosuppressive therapies in paraquat human intoxications

scientific article

Postmortem changes in carbon monoxide poisoning

scientific article published on 01 August 2010

Postmortem redistribution of tramadol and O-desmethyltramadol

scientific article published on 30 September 2013

Preface

scientific article published on 01 October 2015

Presymptomatic MPTP Mice Show Neurotrophic S100B/mRAGE Striatal Levels.

scientific article published on 4 February 2016

Pro-oxidant effects of Ecstasy and its metabolites in mouse brain synaptosomes

scientific article

Profiling of RNA degradation for estimation of post mortem [corrected] interval.

scientific article

Protective effect of acetyl-l-carnitine and α-lipoic acid against the acute toxicity of diepoxybutane to human lymphocytes ⬇️

scientific article published on July 22, 2011

Protective effects of a catechin-rich extract on the hippocampal formation and spatial memory in aging rats

scientific article published on 6 March 2013

Quantification of alpha-amanitin in biological samples by HPLC using simultaneous UV- diode array and electrochemical detection

scientific article published on 10 June 2015

Quantification of morphine and its major metabolites M3G and M6G in antemortem and postmortem samples.

scientific article

Quantification of paraquat in postmortem samples by gas chromatography-ion trap mass spectrometry and review of the literature.

scientific article

Quantitative histochemistry for macrophage biodistribution on mice liver and spleen after the administration of a pharmacological-relevant dose of polyacrylic acid-coated iron oxide nanoparticles

scientific article published on 6 February 2017

RBE4 cells are highly resistant to paraquat-induced cytotoxicity: studies on uptake and efflux mechanisms.

scientific article published on 18 September 2013

Reactivity of paraquat with sodium salicylate: formation of stable complexes.

scientific article published on 26 April 2008

Red wine antioxidants protect hippocampal neurons against ethanol-induced damage: a biochemical, morphological and behavioral study

scientific article

Red wine protects against ethanol-induced oxidative stress in rat liver.

scientific article published in July 2009

Reduced expression of claudin-2 is associated with high histological grade and metastasis of feline mammary carcinomas.

scientific article

Regulation of striatal astrocytic receptor for advanced glycation end-products variants in an early stage of experimental Parkinson's disease

scientific article

Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats

scientific article published on 10 July 2020

Repeated subcutaneous administrations of krokodil causes skin necrosis and internal organs toxicity in Wistar rats: putative human implications.

scientific article published on May 2017

Response to the comment on "Promising blood-derived biomarkers for estimation of the interval"

scientific article published in March 2016

Role of H2O2 in hypertension, renin‐angiotensin system activation and renal medullary disfunction caused by angiotensin II ⬇️

scientific article published on August 1, 2012

Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells

scientific article published in August 2002

Role of superoxide and hydrogen peroxide in hypertension induced by an antagonist of adenosine receptors.

scientific article published on 24 April 2008

Scavenging of nitric oxide by an antagonist of adenosine receptors.

scientific article

Signs and Related Mechanisms of Ethanol Hepatotoxicity.

scientific article published on January 2015

Simultaneous quantification of morphine and cocaine in hair samples from drug addicts by GC-EI/MS.

scientific article

Simultaneous quantification of tramadol and O-desmethyltramadol in hair samples by gas chromatography-electron impact/mass spectrometry

scientific article

Single high dose dexamethasone treatment decreases the pathological score and increases the survival rate of paraquat-intoxicated rats

scientific article published on 03 August 2006

Street-Like Synthesis of Krokodil Results in the Formation of an Enlarged Cluster of Known and New Morphinans.

scientific article published on 14 July 2017

Strenuous exercise aggravates MDMA-induced skeletal muscle damage in mice.

scientific article published on January 2005

Structural isomerization of synephrine influences its uptake and ensuing glutathione depletion in rat-isolated cardiomyocytes

scientific article published on 8 December 2010

Structure-cytotoxicity relationship profile of 13 synthetic cathinones in differentiated human SH-SY5Y neuronal cells

scientific article published on 29 August 2019

Studies on the antioxidant activity of Lippia citriodora infusion: scavenging effect on superoxide radical, hydroxyl radical and hypochlorous acid

scientific article published in October 2002

Suicide by hanging under the influence of ketamine and ethanol

scientific article published on 26 May 2010

Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes

scientific article

Synthesis and analysis of aminochromes by HPLC-photodiode array. Adrenochrome evaluation in rat blood.

scientific article

Synthetic Cannabinoids JWH-122 and THJ-2201 Disrupt Endocannabinoid-Regulated Mitochondrial Function and Activate Apoptotic Pathways as a Primary Mechanism of In Vitro Nephrotoxicity at In Vivo Relevant Concentrations

scientific article published on 01 June 2019

Synthetic cannabinoids JWH-018, JWH-122, UR-144 and the phytocannabinoid THC activate apoptosis in placental cells

scientific article published on 12 November 2019

Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2

scientific article published on 28 November 2018

Synthetic cannabinoids and their impact on neurodevelopmental processes

scientific article published on 23 August 2019

Temperature in the spotlight of drug abuse research

scientific article published on January 2015

The Heart As a Target for Xenobiotic Toxicity: The Cardiac Susceptibility to Oxidative Stress ⬇️

scientific article published on August 23, 2013

The Main Metabolites of Fluorouracil + Adriamycin + Cyclophosphamide (FAC) Are Not Major Contributors to FAC Toxicity in H9c2 Cardiac Differentiated Cells ⬇️

article

The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB1 Receptor-Mediated Neuronal Differentiation at Biologically Relevant Concentrations

scientific article published on 30 August 2020

The age factor for mitoxantrone's cardiotoxicity: multiple doses render the adult mouse heart more susceptible to injury

scientific article published on 9 January 2015

The analytical challenge in the determination of cathinones, key-players in the worldwide phenomenon of novel psychoactive substances.

scientific article published on 13 February 2018

The cardiovascular and cardiac actions of ecstasy and its metabolites.

scientific article published on August 2010

The effects of physical exercise on nonmotor symptoms and on neuroimmune RAGE network in experimental parkinsonism.

scientific article published on 6 April 2017

The harmful chemistry behind "krokodil": Street-like synthesis and product analysis

scientific article published on 3 August 2015

The harmful chemistry behind krokodil (desomorphine) synthesis and mechanisms of toxicity.

scientific article

The metabolism of imidacloprid by aldehyde oxidase contributes to its clastogenic effect in New Zealand rabbits

scientific article published on 19 March 2018

The mixture of "ecstasy" and its metabolites impairs mitochondrial fusion/fission equilibrium and trafficking in hippocampal neurons, at in vivo relevant concentrations.

scientific article published on 4 March 2014

The mixture of "ecstasy" and its metabolites is toxic to human SH-SY5Y differentiated cells at in vivo relevant concentrations

scientific article

The neurotoxicity of amphetamines during the adolescent period

scientific article

The neurotoxicity of hallucinogenic amphetamines in primary cultures of hippocampal neurons

scientific article

The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations

scientific article published on 29 August 2019

The novel psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone): A review

scientific article published on 03 December 2018

The role of foetal red blood cells in protecting cultured lymphocytes against diepoxybutane-induced chromosome breaks.

scientific article published on 27 December 2005

The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis

scientific article published on 3 February 2018

The toxicity of N-methyl-alpha-methyldopamine to freshly isolated rat hepatocytes is prevented by ascorbic acid and N-acetylcysteine

scientific article

The toxicological potential of khat

scientific article published on 01 July 2003

Toxicity of amphetamines: an update

scientific article

Toxicity of the amphetamine metabolites 4-hydroxyamphetamine and 4-hydroxynorephedrine in human dopaminergic differentiated SH-SY5Y cells.

scientific article published on 20 January 2017

Toxicological evaluation of lactose and chitosan delivered by inhalation

scientific article published in January 2008

Toxicological profile of - A narrative review

scientific article published on 09 January 2019

Toxicology as an academic discipline in European Universities

scientific article published on 30 April 2016

Toxicometabolomics: Small Molecules to Answer Big Toxicological Questions

scientific article published in 2021

Use of atropine-treated Daphnia magna survival for detection of environmental contamination by acetylcholinesterase inhibitors.

scientific article

Water extracts of Brassica oleracea var. costata potentiate paraquat toxicity to rat hepatocytes in vitro.

scientific article published on 30 May 2009

Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors.

scientific article

d-Amphetamine Interaction with Glutathione in Freshly Isolated Rat Hepatocytes

scientific article published on 01 September 1996

d-Amphetamine-induced hepatotoxicity: possible contribution of catecholamines and hyperthermia to the effect studied in isolated rat hepatocytes.

scientific article published on January 1997

Paulina is supported by:

About Paulina

Help