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List of works by Guangbiao Zhou

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo.

scientific article published on 12 February 2018

AML1-ETO and C-KIT mutation/overexpression in t(8;21) leukemia: implication in stepwise leukemogenesis and response to Gleevec.

scientific article

Acute promyelocytic leukemia: a model of molecular target based therapy.

scientific article

Air pollution and DNA methylation alterations in lung cancer: A systematic and comparative study.

scientific article

Ambient air pollution and lung disease in China: health effects, study design approaches and future research

journal article published in 2015

Analysis of phenotype-genotype connection: the story of dissecting disease pathogenesis in genomic era in China, and beyond

scientific article published on June 2007

Apoptosis inducement of bigelovin from Inula helianthus-aquatica on human Leukemia U937 cells

scientific article published in June 2009

Arsenic compounds: revived ancient remedies in the fight against human malignancies.

scientific article published on 16 February 2012

Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

scientific article

Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells

scientific article published on August 6, 2010

Biological evaluation of new mimetics of annonaceous acetogenins: alteration of right scaffold by click linkage with aromatic functionalities.

scientific article

Bortezomib interferes with C-KIT processing and transforms the t(8;21)-generated fusion proteins into tumor-suppressing fragments in leukemia cells ⬇️

scientific article published on January 27, 2012

Cancerous inhibitor of PP2A is targeted by natural compound celastrol for degradation in non-small-cell lung cancer.

scientific article

Carcinogens that induce the A:T > T:A nucleotide substitutions in the genome

scientific article published on 5 December 2017

Celastrol induces proteasomal degradation of FANCD2 to sensitize lung cancer cells to DNA crosslinking agents.

scientific article published on 26 May 2015

Design, synthesis of symmetrical bivalent mimetics of annonaceous acetogenins and their cytotoxicities.

scientific article published on 28 April 2011

Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia ⬇️

scholarly article

Dr. Zhen-Yi Wang: Fighting leukemia.

scientific article published on 28 July 2013

Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-kappaB and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner.

scientific article published on 16 June 2006

Ethoxysanguinarine Induces Inhibitory Effects and Downregulates CIP2A in Lung Cancer Cells.

scientific article

From an old remedy to a magic bullet: molecular mechanisms underlying the therapeutic effects of arsenic in fighting leukemia

scientific article

GTF2I-RARA is a novel fusion transcript in a t(7;17) variant of acute promyelocytic leukaemia with clinical resistance to retinoic acid

scientific article published on 4 October 2014

Gambogenic acid induces G1 arrest via GSK3β-dependent cyclin D1 degradation and triggers autophagy in lung cancer cells.

scientific article

Gefitinib analogue V1801 induces apoptosis of T790M EGFR-harboring lung cancer cells by up-regulation of the BH-3 only protein Noxa

scientific article

Identification of a potential tumor suppressor gene, UBL3, in non-small cell lung cancer

scientific article published on 01 February 2020

Identification of an annonaceous acetogenin mimetic, AA005, as an AMPK activator and autophagy inducer in colon cancer cells

scientific article

Identification of novel bivalent mimetics of annonaceous acetogenins via a scaffold-hopping strategy.

scientific article published on 12 March 2014

Indomethacin induces apoptosis and inhibits proliferation in chronic myeloid leukemia cells

scientific article

Largazole Arrests Cell Cycle at G1 Phase and Triggers Proteasomal Degradation of E2F1 in Lung Cancer Cells.

scientific article

Long Non-coding RNAs and Their Roles in Non-small-cell Lung Cancer

scientific article

Long-term efficacy and safety of all-trans retinoic acid/arsenic trioxide-based therapy in newly diagnosed acute promyelocytic leukemia

scholarly article

Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition

scientific article published on 10 April 2019

MUC16 overexpression induced by gene mutations promotes lung cancer cell growth and invasion

scientific article published on 12 January 2018

Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2.

scientific article published on 28 December 2016

Multiregion sequencing reveals the intratumor heterogeneity of driver mutations in TP53-driven non-small cell lung cancer

scientific article published on 20 September 2016

Mutant transcription factors and tyrosine kinases as therapeutic targets for leukemias: from acute promyelocytic leukemia to chronic myeloid leukemia and beyond.

scientific article published on January 2007

Overexpression and small molecule-triggered downregulation of CIP2A in lung cancer ⬇️

scientific article

Potent Antitumor Mimetics of Annonaceous Acetogenins Embedded with an Aromatic Moiety in the Left Hydrocarbon Chain Part ⬇️

scientific article published on December 20, 2010

Potential molecular targets for inhibiting bone invasion by oral squamous cell carcinoma: a review of mechanisms.

scientific article published on June 2012

Retinoic acid and arsenic for treating acute promyelocytic leukemia

scientific article

Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors

scientific article published on 12 October 2015

Skp1: Implications in cancer and SCF-oriented anti-cancer drug discovery.

scientific article published on 26 May 2016

Small compound 6-O-angeloylplenolin induces mitotic arrest and exhibits therapeutic potentials in multiple myeloma

scientific article

Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells.

scientific article published on 8 November 2013

Synergistic targeted therapy for acute promyelocytic leukaemia: a model of translational research in human cancer.

scientific article published on 09 June 2015

Synergy between proteasome inhibitors and imatinib mesylate in chronic myeloid leukemia.

scientific article

Synthesis and biological evaluation of matrine derivatives containing benzo-α-pyrone structure as potent anti-lung cancer agents

scientific article (publication date: 27 October 2016)

Systematic analysis of concentrations of 52 elements in tumor and counterpart normal tissues of patients with non-small cell lung cancer

scientific article published on 23 October 2019

Targeted therapy: The new lease on life for acute promyelocytic leukemia, and beyond.

scientific article published on 19 June 2012

Targeting of AML1-ETO in t(8;21) leukemia by oridonin generates a tumor suppressor-like protein.

scientific article published in March 2012

Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy

scientific article published on 22 May 2018

The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget's disease

scientific article published on 26 May 2020

The chemokine CXCL13 in lung cancers associated with environmental polycyclic aromatic hydrocarbons pollution

scientific article published on 13 November 2015

The epidemic status and risk factors of lung cancer in Xuanwei City, Yunnan Province, China

scientific article published on 07 December 2012

The main anticancer bullets of the Chinese medicinal herb, thunder god vine.

scientific article published on 23 June 2011

The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy

scientific article

The red wine component ellagic acid induces autophagy and exhibits anti-lung cancer activity in vitro and in vivo

scientific article published on 24 October 2018

Tobacco smoke induces production of chemokine CCL20 to promote lung cancer

scientific article

Translating the power of TCM into patients' hope.

scientific article

Translational medicine should translate medical science and technology into health care for everyone in China

article

Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy.

scientific article published on June 2007

Two new terpene glucosides and antitumor agents from Centipeda minima

scientific article published on 01 August 2009

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