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List of works by Kin Tam

A Model of Hereditary Sensory and Autonomic Neuropathy Type 1 Reveals a Role of Glycosphingolipids in Neuronal Polarity

scientific article published on 28 May 2019

A combined spectroscopic and crystallographic approach to probing drug–human serum albumin interactions ⬇️

scientific article published on September 24, 2010

A hydrodynamic approach to the measurement of the permeability of small molecules across artificial membranes.

scientific article published on 14 March 2008

A new high-throughput method utilizing porous silica-based nano-composites for the determination of partition coefficients of drug candidates

scientific article published on 21 July 2011

An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease

scientific article published on 01 October 2020

Anti-cancer synergy of dichloroacetate and EGFR tyrosine kinase inhibitors in NSCLC cell lines

scientific article published on 8 August 2016

Anti-neuroinflammatory effects of SLOH in Aβ-induced BV-2 microglial cells and 3xTg-AD mice involve the inhibition of GSK-3β

scientific article published on 29 September 2018

Anticancer effects of some novel dichloroacetophenones through the inhibition of pyruvate dehydrogenase kinase 1

scientific article published on 18 July 2018

Application of a bi-directional associative memory (BAM) network in computer assisted learning in chemistry

scientific article published on 01 December 1994

Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking

scientific article published on 23 June 2018

Causal interactions in resting-state networks predict perceived loneliness

scientific article

Chemoembolization agents for cancer treatment.

scientific article published on 25 June 2011

Combined use of arginase and dichloroacetate exhibits anti-proliferative effects in triple negative breast cancer cells

scientific article published on 25 October 2018

Comparative Study of Catalytic Hydrogenation of 9-Ethylcarbazole for Hydrogen Storage over Noble Metal Surfaces

Comparison of catalytic performance of supported ruthenium and rhodium for hydrogenation of 9-ethylcarbazole for hydrogen storage applications

scholarly article by Katarzyna Morawa Eblagon et al published 2012 in Energy and Environmental Science

Cytoskeleton Molecular Motors: Structures and Their Functions in Neuron

scientific article

Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents.

scientific article published on April 2015

Dichloroacetophenones targeting at pyruvate dehydrogenase kinase 1 with improved selectivity and antiproliferative activity: Synthesis and structure-activity relationships

scientific article published on 19 September 2018

Discovery of 4-{4-[(3R)-3-Methylmorpholin-4-yl]-6-[1-(methylsulfonyl)cyclopropyl]pyrimidin-2-yl}-1H-indole (AZ20): a potent and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity

scientific article published on March 2013

Dosimetric study for cervix carcinoma treatment using intensity modulated radiation therapy (IMRT) compensation based on 3D intracavitary brachytherapy technique

scientific article published on 14 June 2016

Dual targeting of cholinesterase and amyloid beta with pyridinium/isoquinolium derivatives

scientific article published on 13 December 2019

Editorial, IAPC-5 Special Issue

scientific article published on 29 June 2017

Geniposide improves insulin production and reduces apoptosis in high glucose-induced glucotoxic insulinoma cells.

scientific article

High throughput solubility determination with application to selection of compounds for fragment screening

scientific article

How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?

scientific article published on 01 May 2010

Identification of a Wells-Dawson polyoxometalate-based AP-2γ inhibitor with pro-apoptotic activity

scientific article published on 11 June 2018

Identification of novel pyruvate dehydrogenase kinase 1 (PDK1) inhibitors by kinase activity-based high throughput screening for anticancer therapeutics

scientific article published on 23 October 2018

Immobilization of engineered arginase on gold-carbon nanotubes

scientific article published on 01 August 2012

In situ artificial membrane permeation assay under hydrodynamic control: correlation between drug in vitro permeability and fraction absorbed in humans.

scientific article

In situ artificial membrane permeation assay under hydrodynamic control: permeability-pH profiles of warfarin and verapamil.

scientific article published on 7 May 2010

Inhibition of pyruvate dehydrogenase kinase 1 enhances the anti-cancer effect of EGFR tyrosine kinase inhibitors in non-small cell lung cancer

scientific article published on 10 September 2018

Kinetics and Mechanism of Dyeing Processes: The Dyeing of Cotton Fabrics with a Procion Blue Dichlorotriazinyl Reactive Dye

scientific article published in February 1997

Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer's Disease.

scientific article published on 3 October 2016

Lipophilicity Profiles: Theory and Measurement

article

Liquid Chromatography-Tandem Mass Spectrometry Method Revealed that Lung Cancer Cells Exhibited Distinct Metabolite Profiles upon the Treatment with Different Pyruvate Dehydrogenase Kinase Inhibitors

scientific article published on 31 July 2018

Mechanism of ion transfer in supported liquid membrane systems: electrochemical control over membrane distribution

scientific article published on 16 December 2013

Modern Approaches to Quality Assurance of Drug Formulations.

scientific article published on 20 May 2015

Multiwavelength spectrophotometric determination of acid dissociation constants Part IV. Water-insoluble pyridine derivatives.

scientific article published in July 1999

Multiwavelength spectrophotometric determination of acid dissociation constants of ionizable drugs

scientific article published on 01 August 1998

Multiwavelength spectrophotometric determination of acid dissociation constants part V: microconstants and tautomeric ratios of diprotic amphoteric drugs

scientific article published on 01 January 2000

Multiwavelength spectrophotometric determination of acid dissociation constants: Part III. Resolution of multi-protic ionization systems

scientific article published in June 1999

Multiwavelength spectrophotometric resolution of the micro-equilibria of cetirizine

scientific article

Neuroprotective Effect of SLM, a Novel Carbazole-Based Fluorophore, on SH-SY5Y Cell Model and 3xTg-AD Mouse Model of Alzheimer's Disease

scientific article

New magnetic nano-absorbent for the determination of n-octanol/water partition coefficients

scientific article published in June 2005

Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI-Mediated Anticancer Activity in NSCLC

scientific article published on 23 August 2019

PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent-water mixtures

scientific article published in August 1999

Permeation of a fully ionized species across a polarized supported liquid membrane

scientific article published on 22 February 2012

Pharmacokinetics screening for multi-components absorbed in the rat plasma after oral administration of traditional Chinese medicine Flos Lonicerae Japonicae-Fructus Forsythiae herb couple by sequential negative and positive ionization ultra-high-pe

scientific article published on 15 December 2014

Pharmacological synergism of 2,2-dichloroacetophenone and EGFR-TKi to overcome TKi-induced resistance in NSCLC cells

scientific article published in September 2017

Phenyl butyrate inhibits pyruvate dehydrogenase kinase 1 and contributes to its anti-cancer effect

scientific article published on 24 April 2017

Predicting the exposure and antibacterial activity of fluoroquinolones based on physicochemical properties

scientific article published on 8 May 2012

Predicting the human jejunal permeability and fraction absorbed of fluoroquinolones based on a biophysical model

scientific article published on 01 January 2014

Predicting the minimal inhibitory concentration of fluoroquinolones for Escherichia coli using an accumulation model

scientific article

Preparation of nanomagnetic absorbent for partition coefficient measurement

scientific article published on 22 July 2006

Quantification of permanent positively charged compounds in plasma using one-step dilution to reduce matrix effect in MS

scientific article published on 26 February 2016

Quinazolinone azolyl ethanols: potential lead antimicrobial agents with dual action modes targeting methicillin-resistant Staphylococcus aureus DNA.

scientific article published on 26 September 2016

SLM, a novel carbazole-based fluorophore attenuates okadaic acid-induced tau hyperphosphorylation via down-regulating GSK-3β activity in SH-SY5Y cells

scientific article published on 27 March 2017

SLOH, a carbazole-based fluorophore, mitigates neuropathology and behavioral impairment in the triple-transgenic mouse model of Alzheimer's disease

scientific article published on 5 January 2018

Silica-encapsulated nanomagnetic particle as a new recoverable biocatalyst carrier

scientific article published on 01 August 2006

Simultaneous multiwavelength study of the reaction of phenolphthalein with sodium hydroxide

scientific article published on January 1992

Spectrophotometric pKa determination of ionizable pharmaceuticals: Resolution of molecules with weak pH-dependent spectral shift

scientific article

Sphingolipidomic Analysis of C. elegans reveals Development- and Environment-dependent Metabolic Features

scientific article published on 08 November 2019

Study of Catalytic Sites on Ruthenium For Hydrogenation of N-ethylcarbazole: Implications of Hydrogen Storage via Reversible Catalytic Hydrogenation

scholarly article by Katarzyna Morawa Eblagon et al published 6 May 2010 in Journal of Physical Chemistry C

Study the interactions between human serum albumin and two antifungal drugs: fluconazole and its analogue DTP.

scientific article published on 20 September 2014

Synthesis and biological evaluation of (R)-3,3,3-trifluoro-2-hydroxy-2-methylpropionamides as pyruvate dehydrogenase kinase 1 (PDK1) inhibitors to reduce the growth of cancer cells

scientific article published on 24 March 2017

Synthesis and biological evaluation of aza-crown ether-squaramide conjugates as anion/cation symporters

scientific article published on 01 May 2019

Synthesis and characterization of thiol-capped FePt nanomagnetic porous particles

scientific article published on 01 October 2005

Systemic clearance and brain distribution of carbazole-based cyanine compounds as Alzheimer's disease drug candidates

scientific article published on 27 November 2017

Targeting Tumor Metabolism for Cancer Treatment: Is Pyruvate Dehydrogenase Kinases (PDKs) a Viable Anticancer Target?

scientific article

Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors

scientific article published on 08 May 2018

The Scalp Time-Varying Networks of N170: Reference, Latency, and Information Flow.

scientific article

The discovery of AZD5597, a potent imidazole pyrimidine amide CDK inhibitor suitable for intravenous dosing

scientific article

The permeation of amphoteric drugs through artificial membranes--an in combo absorption model based on paracellular and transmembrane permeability

scientific article published on 01 January 2010

Unexpected Discovery of Dichloroacetate Derived Adenosine Triphosphate Competitors Targeting Pyruvate Dehydrogenase Kinase To Inhibit Cancer Proliferation

scientific article published on 30 March 2016

Using droplet-based microfluidic technology to study the precipitation of a poorly water-soluble weakly basic drug upon a pH-shift

scientific article

pH-metric logP 10. Determination of liposomal membrane-water partition coefficients of ionizable drugs

scientific article published on 01 February 1998

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