List of works - Catalina Pico

2-Methoxyestradiol, an endogenous metabolite of 17beta-estradiol, inhibits adipocyte proliferation.

scientific article published on December 1998

A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study

scientific article

A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet.

scientific article published on 22 November 2016

A physiological role of breast milk leptin in body weight control in developing infants

scientific article published in August 2006

A significant pool of amino acids is adsorbed on blood cell membranes

scientific article published on 01 August 1991

Alterations in plasma acylcarnitine and amino acid profiles may indicate poor nutrition during the suckling period due to maternal intake of an unbalanced diet and may predict later metabolic dysfunction

scientific article published on 06 August 2018

BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology

scientific article

Beta-carotene affects oxidative stress-related DNA damage in lung epithelial cells and in ferret lung

scientific article published in December 2009

Blood cell transcript levels in 5-year-old children as potential markers of breastfeeding effects in those small for gestational age at birth

scientific article published on 07 May 2019

Blood cell transcriptomic-based early biomarkers of adverse programming effects of gestational calorie restriction and their reversibility by leptin supplementation

scientific article

Blood cells as a source of transcriptional biomarkers of childhood obesity and its related metabolic alterations: results of the IDEFICS study

scientific article published on 25 January 2012

Blood leptin homeostasis: sex-associated differences in circulating leptin levels in rats are independent of tissue leptin expression

scientific article published on 01 January 2003

Brown adipose tissue response to cafeteria diet-feeding involves induction of the UCP2 gene and is impaired in female rats as compared to males

scientific article published on 01 October 1999

CONSENSUS ON FATS AND OILS IN THE DIET OF S ISH ADULTS; POSITION PAPER OF THE SPANISH FEDERATION OF FOOD, NUTRITION AND DIETETICS SOCIETIES

scientific article published on August 2015

Cafeteria diet overfeeding in young male rats impairs the adaptive response to fed/fasted conditions and increases adiposity independent of body weight.

scientific article published on 21 July 2014

Cohort Profile: The transition from childhood to adolescence in European children-how I.Family extends the IDEFICS cohort

scientific article published on 31 December 2016

Combination of Capsaicin and Hesperidin Reduces the Effectiveness of Each Compound To Decrease the Adipocyte Size and To Induce Browning Features in Adipose Tissue of Western Diet Fed Rats

scientific article published on 05 September 2018

Decrease of the pool of amino acids adsorbed on blood cell membranes caused by starvation in rats

scientific article published on 01 January 1995

Dietary l-leucine supplementation of lactating rats results in a tendency to increase lean/fat ratio associated to lower orexigenic neuropeptide expression in hypothalamus.

scientific article published on 27 March 2010

Differential expression of genes for uncoupling proteins 1, 2 and 3 in brown and white adipose tissue depots during rat development

scientific article published on 01 March 2001

Diurnal rhythms of leptin and ghrelin in the systemic circulation and in the gastric mucosa are related to food intake in rats

scientific article published on 24 April 2004

Early alterations in plasma ghrelin levels in offspring of calorie-restricted rats during gestation may be linked to lower sympathetic drive to the stomach

scientific article published on 16 November 2012

Early biomarkers identified in a rat model of a healthier phenotype based on early postnatal dietary intervention may predict the response to an obesogenic environment in adulthood

scientific article

Effect of high-fat diet feeding on leptin receptor expression in white adipose tissue in rats: depot- and sex-related differential response

scientific article published on 10 March 2009

Effect of selective β-adrenoceptor stimulation on UCP synthesis in primary cultures of brown adipocytes

article

Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets

scientific article published on 24 July 2007

Effects of beta-carotene supplementation on adipose tissue thermogenic capacity in ferrets (Mustela putorius furo).

scientific article published on 27 July 2009

Effects of trans-10, cis-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet.

scientific article published on 7 March 2007

Enhancing hepatic fatty acid oxidation as a strategy for reversing metabolic disorders programmed by maternal undernutrition during gestation

scientific article published on 14 May 2014

Erythrocyte uptake kinetics and cell to plasma gradients of leucine and phenylalanine in fed and fasted rats

scientific article published in March 1993

Food safety and functional foods in the European Union: obesity as a paradigmatic example for novel food development.

scientific article published in July 2004

Formation of hemoglobin adducts of acrylamide after its ingestion in rats is dependent on age and sex.

scientific article published on 10 June 2008

Gene expression patterns in visceral and subcutaneous adipose depots in rats are linked to their morphologic features.

scientific article published on 4 November 2009

Genetics and Nutrigenomics of Obesity

article

Hesperidin and capsaicin, but not the combination, prevent hepatic steatosis and other metabolic syndrome-related alterations in western diet-fed rats

scientific article published in Scientific Reports

Identification of early transcriptome-based biomarkers related to lipid metabolism in peripheral blood mononuclear cells of rats nutritionally programmed for improved metabolic health

scientific article published on 17 December 2013

Impaired insulin and leptin sensitivity in the offspring of moderate caloric-restricted dams during gestation is early programmed

scientific article published on 23 March 2012

In vitro adsorption of amino acids onto isolated rat erythrocyte membranes

scientific article published in August 1995

In vivo effects of CGP-12177 on the expression of leptin and uncoupling protein genes in mouse brown and white adipose tissues

article

Induction of NPY/AgRP orexigenic peptide expression in rat hypothalamus is an early event in fasting: relationship with circulating leptin, insulin and glucose

scientific article published on 18 February 2009

Integration of risk and benefit analysis-the window of benefit as a new tool?

scientific article published on August 2009

Leptin Intake at Physiological Doses Throughout Lactation in Male Wistar Rats Normalizes the Decreased Density of Tyrosine Hydroxylase-Immunoreactive Fibers in the Stomach Caused by Mild Gestational Calorie Restriction.

scientific article published on 21 March 2018

Leptin Orally Supplied to Neonate Rats Is Directly Uptaken by the Immature Stomach and May Regulate Short-Term Feeding

scientific article published on 03 March 2005

Leptin as a breast milk component for the prevention of obesity

scientific article published on 01 December 2018

Leptin in the human stomach.

scientific article published in July 2001

Leptin intake during lactation prevents obesity and affects food intake and food preferences in later life.

scientific article published on 24 September 2008

Leptin intake in suckling rats restores altered T3 levels and markers of adipose tissue sympathetic drive and function caused by gestational calorie restriction

scientific article published on 18 March 2015

Leptin production by the stomach is up-regulated in obese (fa/fa) Zucker rats

scientific article published in September 2002

Maternal consumption of a cafeteria diet during lactation in rats leads the offspring to a thin-outside-fat-inside phenotype.

scientific article published on 13 February 2017

Maternal dietary fat affects milk fatty acid profile and impacts on weight gain and thermogenic capacity of suckling rats.

scientific article published on 16 February 2013

Maternal fat supplementation during late pregnancy and lactation influences the development of hepatic steatosis in offspring depending on the fat source

scientific article published on 6 February 2014

Maternal supplementation with an excess of different fat sources during pregnancy and lactation differentially affects feeding behavior in offspring: putative role of the leptin system

scientific article published on 5 October 2012

Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction

scientific article

Metabolic programming of sirtuin 1 (SIRT1) expression by moderate energy restriction during gestation in rats may be related to obesity susceptibility in later life

scientific article published on 28 May 2012

Metabolic utilization of muscular L-proline in 24-hr starved rats

scientific article published in November 1992

Moderate caloric restriction during gestation in rats alters adipose tissue sympathetic innervation and later adiposity in offspring

scientific journal article

Moderate caloric restriction in lactating rats programs their offspring for a better response to HF diet feeding in a sex-dependent manner.

scientific article published on 20 October 2010

Moderate caloric restriction in lactating rats protects offspring against obesity and insulin resistance in later life

scientific article published on 12 January 2010

Moderate calorie restriction during gestation programs offspring for lower BAT thermogenic capacity driven by thyroid and sympathetic signaling

scientific article published on 03 April 2014

Morphology of ferret subcutaneous adipose tissue after 6-month daily supplementation with oral beta-carotene

scientific article published on 17 November 2004

Nutrient-gene interactions in benefit-risk analysis.

scientific article published on June 2006

Nutrigenomic approaches for benefit-risk analysis of foods and food components: defining markers of health

article

Nutritional potential of metabolic remodelling of white adipose tissue.

scientific article

Obesity: molecular bases of a multifactorial problem.

scientific article

Offspring predisposition to obesity due to maternal-diet-induced obesity in rats is preventable by dietary normalization before mating.

scientific article published on 29 October 2016

Ontogenesis of leptin expression in different adipose tissue depots in the rat.

scientific article published in June 2001

Opposite effects of feeding a vitamin A-deficient diet and retinoic acid treatment on brown adipose tissue uncoupling protein 1 (UCP1), UCP2 and leptin expression

scientific article published on 01 September 2000

Oral leptin supplementation throughout lactation in rats prevents later metabolic alterations caused by gestational calorie restriction

scientific article published on 28 December 2016

Oral leptin treatment in suckling rats ameliorates detrimental effects in hypothalamic structure and function caused by maternal caloric restriction during gestation

scientific article

Oral supplementation with physiological doses of leptin during lactation in rats improves insulin sensitivity and affects food preferences later in life.

scientific article published on 8 November 2007

Pectin supplementation in rats mitigates age-related impairment in insulin and leptin sensitivity independently of reducing food intake

scientific article

Perinatal expression of leptin in rat stomach

scientific article published on 01 January 2002

Perinatal programming of body weight control by leptin: putative roles of AMP kinase and muscle thermogenesis

scientific article published on 4 May 2011

Perinatal programming of obesity: an introduction to the topic

scientific article published on 17 September 2013

Positive correlation of skeletal muscle UCP3 mRNA levels with overweight in male, but not in female, rats.

scientific article published on 15 May 2003

Prospective associations between dietary patterns and high sensitivity C-reactive protein in European children: the IDEFICS study

scientific article published on 18 March 2017

Protective effects of leptin during the suckling period against later obesity may be associated with changes in promoter methylation of the hypothalamic pro-opiomelanocortin gene

article

Protein and amino acid intake in cafeteria fed obese rats

scientific article published on 01 September 1995

Rats receiving the slimming agent oleoyl-estrone in liposomes (Merlin-2) decrease food intake but maintain thermogenesis

scientific article published in December 1997

Regional differences in the expression of genes involved in lipid metabolism in adipose tissue in response to short- and medium-term fasting and refeeding

scientific journal article

Regulation of rat erythrocyte L-glutamine, L-glutamate and L-lysine uptake by short term starvation

scientific article published in November 1992

Resistin as a putative modulator of insulin action in the daily feeding/fasting rhythm.

scientific article published on 11 January 2006

Resistin expression in different adipose tissue depots during rat development

scientific article published on October 1, 2003

Response to carbohydrate and fat refeeding in the expression of genes involved in nutrient partitioning and metabolism: striking effects on fibroblast growth factor-21 induction.

scientific article published on 16 October 2009

Retinoic acid modulates retinoid X receptor α and retinoic acid receptor α levels of cultured brown adipocytes

scientific article published on 01 April 1997

Role of leptin present in maternal milk in the control of energy balance during the post-natal period

scientific article published on October 2007

Screening of potential anti-adipogenic effects of phenolic compounds showing different chemical structure in 3T3-L1 preadipocytes.

scientific article published on 8 September 2017

Secretory granules of endocrine and chief cells of human stomach mucosa contain leptin

scientific article published on 01 June 2000

Sex-associated differences in cold-induced UCP1 synthesis in rodent brown adipose tissue

scientific article published in October 1998

Sex-differential expression of metabolism-related genes in response to a high-fat diet

scientific article published on 24 January 2008

Sexual Dimorphism in the Age-Induced Insulin Resistance, Liver Steatosis, and Adipose Tissue Function in Rats.

scientific article published on 11 July 2017

Sexual dimorphism in age-related changes in UCP2 and leptin gene expression in subcutaneous adipose tissue in humans

article

Stimulation of uncoupling protein synthesis in white adipose tissue of mice treated with the β3-adrenergic agonist CGP-12177

scientific article published on 01 February 1998

Summary and general conclusions/outcomes on the role and fate of sugars in human nutrition and health.

scientific article published on March 2009

Sustained changes in blood alpha amino nitrogen compartmentation during recovery from cafeteria feeding in rats

scientific article published on 01 August 1991

The different satiating capacity of CHO and fats can be mediated by different effects on leptin and ghrelin systems

scientific article published on 5 May 2010

The inhibition of gastric ghrelin production by food intake in rats is dependent on the type of macronutrient.

scientific article published on 29 July 2004

The intake of a high-fat diet triggers higher brown adipose tissue UCP1 levels in male rats but not in females.

scientific article published on October 2007

The intake of a hyperlipidic diet stimulates the gastric leptin signalling pathway in female rats.

scientific article published on October 2007

The uncoupling protein, thermogenin.

scientific article

Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells.

scientific article

Tissue composition in persistent dietary obesity after early and adulthood overfeeding in the rat

article

Transcriptome analysis in blood cells from children reveals potential early biomarkers of metabolic alterations

scientific article published on 6 June 2017

UCP1 and oxidative capacity of adipose tissue in adult ferrets (Mustela putorius furo).

scientific article published on 20 January 2009

White adipose tissue reference network: a knowledge resource for exploring health-relevant relations

scientific article

“In Vivo” Glutamic Acid Metabolism in Late Pregnant Rats

scientific article published on 01 June 1993

List of works by Catalina Pico

2-Methoxyestradiol, an endogenous metabolite of 17beta-estradiol, inhibits adipocyte proliferation.

A Common Variant and the Transcript Levels of MC4R Gene Are Associated With Adiposity in Children: The IDEFICS Study

A combination of resveratrol and quercetin induces browning in white adipose tissue of rats fed an obesogenic diet.

A physiological role of breast milk leptin in body weight control in developing infants

A significant pool of amino acids is adsorbed on blood cell membranes

Alterations in plasma acylcarnitine and amino acid profiles may indicate poor nutrition during the suckling period due to maternal intake of an unbalanced diet and may predict later metabolic dysfunction

BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology

Beta-carotene affects oxidative stress-related DNA damage in lung epithelial cells and in ferret lung

Blood cell transcript levels in 5-year-old children as potential markers of breastfeeding effects in those small for gestational age at birth

Blood cell transcriptomic-based early biomarkers of adverse programming effects of gestational calorie restriction and their reversibility by leptin supplementation

Blood cells as a source of transcriptional biomarkers of childhood obesity and its related metabolic alterations: results of the IDEFICS study

Blood leptin homeostasis: sex-associated differences in circulating leptin levels in rats are independent of tissue leptin expression

Brown adipose tissue response to cafeteria diet-feeding involves induction of the UCP2 gene and is impaired in female rats as compared to males

CONSENSUS ON FATS AND OILS IN THE DIET OF S ISH ADULTS; POSITION PAPER OF THE SPANISH FEDERATION OF FOOD, NUTRITION AND DIETETICS SOCIETIES

Cafeteria diet overfeeding in young male rats impairs the adaptive response to fed/fasted conditions and increases adiposity independent of body weight.

Cohort Profile: The transition from childhood to adolescence in European children-how I.Family extends the IDEFICS cohort

Combination of Capsaicin and Hesperidin Reduces the Effectiveness of Each Compound To Decrease the Adipocyte Size and To Induce Browning Features in Adipose Tissue of Western Diet Fed Rats

Decrease of the pool of amino acids adsorbed on blood cell membranes caused by starvation in rats

Dietary l-leucine supplementation of lactating rats results in a tendency to increase lean/fat ratio associated to lower orexigenic neuropeptide expression in hypothalamus.

Differential expression of genes for uncoupling proteins 1, 2 and 3 in brown and white adipose tissue depots during rat development

Diurnal rhythms of leptin and ghrelin in the systemic circulation and in the gastric mucosa are related to food intake in rats

Early alterations in plasma ghrelin levels in offspring of calorie-restricted rats during gestation may be linked to lower sympathetic drive to the stomach

Early biomarkers identified in a rat model of a healthier phenotype based on early postnatal dietary intervention may predict the response to an obesogenic environment in adulthood

Effect of high-fat diet feeding on leptin receptor expression in white adipose tissue in rats: depot- and sex-related differential response

Effect of selective β-adrenoceptor stimulation on UCP synthesis in primary cultures of brown adipocytes

Effects of 6-month daily supplementation with oral beta-carotene in combination or not with benzo[a]pyrene on cell-cycle markers in the lung of ferrets

Effects of beta-carotene supplementation on adipose tissue thermogenic capacity in ferrets (Mustela putorius furo).

Effects of trans-10, cis-12 conjugated linoleic acid on the expression of uncoupling proteins in hamsters fed an atherogenic diet.

Enhancing hepatic fatty acid oxidation as a strategy for reversing metabolic disorders programmed by maternal undernutrition during gestation

Erythrocyte uptake kinetics and cell to plasma gradients of leucine and phenylalanine in fed and fasted rats

Food safety and functional foods in the European Union: obesity as a paradigmatic example for novel food development.

Formation of hemoglobin adducts of acrylamide after its ingestion in rats is dependent on age and sex.

Gene expression patterns in visceral and subcutaneous adipose depots in rats are linked to their morphologic features.

Genetics and Nutrigenomics of Obesity

Hesperidin and capsaicin, but not the combination, prevent hepatic steatosis and other metabolic syndrome-related alterations in western diet-fed rats

Identification of early transcriptome-based biomarkers related to lipid metabolism in peripheral blood mononuclear cells of rats nutritionally programmed for improved metabolic health

Impaired insulin and leptin sensitivity in the offspring of moderate caloric-restricted dams during gestation is early programmed

In vitro adsorption of amino acids onto isolated rat erythrocyte membranes

In vivo effects of CGP-12177 on the expression of leptin and uncoupling protein genes in mouse brown and white adipose tissues

Induction of NPY/AgRP orexigenic peptide expression in rat hypothalamus is an early event in fasting: relationship with circulating leptin, insulin and glucose

Integration of risk and benefit analysis-the window of benefit as a new tool?

Leptin Intake at Physiological Doses Throughout Lactation in Male Wistar Rats Normalizes the Decreased Density of Tyrosine Hydroxylase-Immunoreactive Fibers in the Stomach Caused by Mild Gestational Calorie Restriction.

Leptin Orally Supplied to Neonate Rats Is Directly Uptaken by the Immature Stomach and May Regulate Short-Term Feeding

Leptin as a breast milk component for the prevention of obesity

Leptin in the human stomach.

Leptin intake during lactation prevents obesity and affects food intake and food preferences in later life.

Leptin intake in suckling rats restores altered T3 levels and markers of adipose tissue sympathetic drive and function caused by gestational calorie restriction

Leptin production by the stomach is up-regulated in obese (fa/fa) Zucker rats

Maternal consumption of a cafeteria diet during lactation in rats leads the offspring to a thin-outside-fat-inside phenotype.

Maternal dietary fat affects milk fatty acid profile and impacts on weight gain and thermogenic capacity of suckling rats.

Maternal fat supplementation during late pregnancy and lactation influences the development of hepatic steatosis in offspring depending on the fat source

Maternal supplementation with an excess of different fat sources during pregnancy and lactation differentially affects feeding behavior in offspring: putative role of the leptin system

Metabolic programming of obesity by energy restriction during the perinatal period: different outcomes depending on gender and period, type and severity of restriction

Metabolic programming of sirtuin 1 (SIRT1) expression by moderate energy restriction during gestation in rats may be related to obesity susceptibility in later life

Metabolic utilization of muscular L-proline in 24-hr starved rats

Moderate caloric restriction during gestation in rats alters adipose tissue sympathetic innervation and later adiposity in offspring

Moderate caloric restriction in lactating rats programs their offspring for a better response to HF diet feeding in a sex-dependent manner.

Moderate caloric restriction in lactating rats protects offspring against obesity and insulin resistance in later life

Moderate calorie restriction during gestation programs offspring for lower BAT thermogenic capacity driven by thyroid and sympathetic signaling

Morphology of ferret subcutaneous adipose tissue after 6-month daily supplementation with oral beta-carotene

Nutrient-gene interactions in benefit-risk analysis.

Nutrigenomic approaches for benefit-risk analysis of foods and food components: defining markers of health

Nutritional potential of metabolic remodelling of white adipose tissue.

Obesity: molecular bases of a multifactorial problem.

Offspring predisposition to obesity due to maternal-diet-induced obesity in rats is preventable by dietary normalization before mating.

Ontogenesis of leptin expression in different adipose tissue depots in the rat.

Opposite effects of feeding a vitamin A-deficient diet and retinoic acid treatment on brown adipose tissue uncoupling protein 1 (UCP1), UCP2 and leptin expression

Oral leptin supplementation throughout lactation in rats prevents later metabolic alterations caused by gestational calorie restriction

Oral leptin treatment in suckling rats ameliorates detrimental effects in hypothalamic structure and function caused by maternal caloric restriction during gestation

Oral supplementation with physiological doses of leptin during lactation in rats improves insulin sensitivity and affects food preferences later in life.

Pectin supplementation in rats mitigates age-related impairment in insulin and leptin sensitivity independently of reducing food intake

Perinatal expression of leptin in rat stomach

Perinatal programming of body weight control by leptin: putative roles of AMP kinase and muscle thermogenesis

Perinatal programming of obesity: an introduction to the topic

Positive correlation of skeletal muscle UCP3 mRNA levels with overweight in male, but not in female, rats.

Prospective associations between dietary patterns and high sensitivity C-reactive protein in European children: the IDEFICS study

Protective effects of leptin during the suckling period against later obesity may be associated with changes in promoter methylation of the hypothalamic pro-opiomelanocortin gene

Protein and amino acid intake in cafeteria fed obese rats

Rats receiving the slimming agent oleoyl-estrone in liposomes (Merlin-2) decrease food intake but maintain thermogenesis