List of works by George Dimopoulos

A cell surface mucin specifically expressed in the midgut of the malaria mosquito Anopheles gambiae

scientific article

AME evidence series 001-The Society for Translational Medicine: clinical practice guidelines for diagnosis and early identification of sepsis in the hospital

scientific article

Aedes aegypti ML and Niemann-Pick type C family members are agonists of dengue virus infection

scientific article published on 14 October 2013

Aedes aegypti Toll pathway is induced through dsRNA sensing in endosomes

scientific article published in 2021

AgDscam, a hypervariable immunoglobulin domain-containing receptor of the Anopheles gambiae innate immune system

scientific article

Amino acid metabolic signaling influences Aedes aegypti midgut microbiome variability.

scientific article published on 28 July 2017

Aminopeptidase secreted by Chromobacterium sp. Panama inhibits dengue virus infection by degrading the E protein.

scientific article published on 25 April 2018

An Aedes aegypti-associated fungus increases susceptibility to dengue virus by modulating gut trypsin activity

scientific article published on 5 December 2017

An evolutionary conserved function of the JAK-STAT pathway in anti-dengue defense

scientific article

Analysis of the Plasmodium and Anopheles transcriptional repertoire during ookinete development and midgut invasion.

scientific article

Analysis of the Plasmodium and Anopheles transcriptomes during oocyst differentiation

scientific article

Anopheles Imd pathway factors and effectors in infection intensity-dependent anti-Plasmodium action

scientific article

Anopheles NF-κB-regulated splicing factors direct pathogen-specific repertoires of the hypervariable pattern recognition receptor AgDscam.

scientific article published on October 2012

Anopheles fibrinogen-related proteins provide expanded pattern recognition capacity against bacteria and malaria parasites

scientific article published on 04 February 2009

Anopheles gambiae Lacking AgTRIO Inefficiently Transmits Plasmodium berghei to Mice

scientific article published on 21 August 2019

Anopheles gambiae immune responses to Sephadex beads: involvement of anti-Plasmodium factors in regulating melanization

scientific article published on 11 August 2006

Anopheles gambiae immune responses to human and rodent Plasmodium parasite species

scientific article

Anopheles gambiae pilot gene discovery project: identification of mosquito innate immunity genes from expressed sequence tags generated from immune-competent cell lines

scientific article published on June 2000

Anopheles infection responses; laboratory models versus field malaria transmission systems

scientific article

Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

scientific article published on 09 June 2020

Attributable mortality of Stenotrophomonas maltophilia infections: a systematic review of the literature

scientific article

Bacteria- and IMD pathway-independent immune defenses against Plasmodium falciparum in Anopheles gambiae

scientific article

Bacterial natural products in the fight against mosquito-transmitted tropical diseases

scientific article published on 01 March 2020

Bayesian coclustering of Anopheles gene expression time series: study of immune defense response to multiple experimental challenges.

scientific article

Broad spectrum immunomodulatory effects of Anopheles gambiae microRNAs and their use for transgenic suppression of Plasmodium

scientific article published on 24 April 2020

Building a better mosquito: identifying the genes enabling malaria and dengue fever resistance in A. gambiae and A. aegypti mosquitoes

scientific article published on 4 July 2007

CRISPR/Cas9 -mediated gene knockout of Anopheles gambiae FREP1 suppresses malaria parasite infection.

scientific article published on 8 March 2018

CTRP is essential for mosquito infection by malaria ookinetes

scientific article

Caspar controls resistance to Plasmodium falciparum in diverse anopheline species

scientific article

Caudal is a negative regulator of the Anopheles IMD pathway that controls resistance to Plasmodium falciparum infection

scientific article

Challenges and approaches for mosquito targeted malaria control

scientific article

Changes in the microbiota cause genetically modified Anopheles to spread in a population.

scientific article published on 28 September 2017

Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study

scientific article

Characterization of the Rel2-regulated transcriptome and proteome of Anopheles stephensi identifies new anti-Plasmodium factors

scientific article

Chloroquine mediated modulation of Anopheles gambiae gene expression

scientific article

Chromobacterium Csp_P reduces malaria and dengue infection in vector mosquitoes and has entomopathogenic and in vitro anti-pathogen activities

scientific article

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin.

scientific article published on 18 April 2018

Cloning and analysis of a cecropin gene from the malaria vector mosquito, Anopheles gambiae

scientific article published in February 2000

Cloning and molecular characterization of two mosquito iron regulatory proteins

scientific article published in May 2002

Clostridioides difficile (formerly Clostridium difficile) infection in the critically ill: an expert statement

scientific article published on 14 January 2020

Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster

scientific article (publication date: 4 October 2002)

Comprehensive DNA methylation analysis of the Aedes aegypti genome

scientific article (publication date: 2 November 2016)

Continuous exposure to Plasmodium results in decreased susceptibility and transcriptomic divergence of the Anopheles gambiae immune system

scientific article

Dengue virus infection of the Aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior

scientific article

Dengue virus inhibits immune responses in Aedes aegypti cells

scientific article

Detailed Analyses of Zika Virus Tropism in Culex quinquefasciatus Reveal Systemic Refractoriness

scientific article published on 18 August 2020

Discovery of insect and human dengue virus host factors

scientific article

Does contemporary vancomycin dosing achieve therapeutic targets in a heterogeneous clinical cohort of critically ill patients? Data from the multinational DALI study

scientific article

Dual roles for the ER membrane protein complex in flavivirus infection: viral entry and protein biogenesis

scientific article published on 04 July 2019

Engineered Aedes aegypti JAK/STAT Pathway-Mediated Immunity to Dengue Virus

scientific article

Engineered anopheles immunity to Plasmodium infection

scientific article

Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes

scientific article

Exploring Anopheles gut bacteria for Plasmodium blocking activity

scientific article

Field-deployable molecular diagnostic platform for arbovirus detection in Aedes aegypti

scientific article published on 24 September 2020

Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: a meta-analysis of randomized controlled trials

scientific article

Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence.

scientific article published on 22 August 2016

Functional genomics studies on the innate immunity of disease vectors

Gambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae

scientific article

Gametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activity

scientific article

Gene discovery in an invasive tephritid model pest species, the Mediterranean fruit fly, Ceratitis capitata. ⬇️

scientific article

Genetic modification of Anopheles stephensi for resistance to multiple Plasmodium falciparum strains does not influence susceptibility to o'nyong'nyong virus or insecticides, or Wolbachia-mediated resistance to the malaria parasite.

scientific article published on 10 April 2018

Genome expression analysis of Anopheles gambiae: responses to injury, bacterial challenge, and malaria infection

scientific article

Genome sequence of Aedes aegypti, a major arbovirus vector

scientific article

Genome-wide analysis of transcriptomic divergence between laboratory colony and field Anopheles gambiae mosquitoes of the M and S molecular forms

scientific article

Genome-wide transcriptomic profiling of Anopheles gambiae hemocytes reveals pathogen-specific signatures upon bacterial challenge and Plasmodium berghei infection

scientific article

Global gene expression analysis of Anopheles gambiae responses to microbial challenge

scientific article published in April 2005

Hydrogen cyanide produced by the soil bacterium Chromobacterium sp. Panama contributes to mortality in Anopheles gambiae mosquito larvae.

scientific article

Identification and characterization of differentially expressed cDNAs of the vector mosquito, Anopheles gambiae.

scientific article published on November 1996

Identification of anti-flaviviral drugs with mosquitocidal and anti-Zika virus activity in Aedes aegypti

scientific article published on 20 August 2019

Immediate post-operative effects of tracheotomy on respiratory function during mechanical ventilation

scientific article

Immunity-related genes and gene families in Anopheles gambiae

scientific article published in October 2002

Immunoglobulin superfamily members play an important role in the mosquito immune system

scientific article published on 6 November 2007

Implication of the mosquito midgut microbiota in the defense against malaria parasites

scientific article published on 08 May 2009

Innate immune defense against malaria infection in the mosquito.

scientific article

Insect immunity and its implication in mosquito-malaria interactions

scientific article

Intensive care medicine research agenda on invasive fungal infection in critically ill patients

scientific article

Long non-coding RNAs regulate Aedes aegypti vector competence for Zika virus and reproduction

scientific article published in 2023

Low- and high-tech approaches to control Plasmodium parasite transmission by anopheles mosquitoes

scientific article

MOSQUITO IMMUNITY TO THE MALARIA PARASITE

scholarly article published 2008

Malaria infection of the mosquito Anopheles gambiae activates immune-responsive genes during critical transition stages of the parasite life cycle.

scientific article

Microbial Diversity of Adult Aedes aegypti and Water Collected from Different Mosquito Aquatic Habitats in Puerto Rico

scientific article published in 2021

Molecular analysis of Culex quinquefasciatus larvae responses to Lysinibacillus sphaericus Bin toxin.

scientific article

Molecular analysis of photic inhibition of blood-feeding in Anopheles gambiae

scientific article

Molecular discrimination of mosquito vectors and their pathogens

scientific article published on October 2009

Molecular immune responses of the mosquito Anopheles gambiae to bacteria and malaria parasites.

scientific article published on October 1997

Mosquito Infection Responses to Developing Filarial Worms

scientific article

Mosquito gut antiparasitic and antiviral immunity

scientific article

Mosquito immune defenses against Plasmodium infection

scientific article

Mosquito immunity against arboviruses

scientific article

Native microbiota shape insect vector competence for human pathogens.

scientific article

Natural microbe-mediated refractoriness to Plasmodium infection in Anopheles gambiae

scientific article

P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions

scientific article

Pathogenomics of Culex quinquefasciatus and meta-analysis of infection responses to diverse pathogens

scientific article

Pharmacokinetic variability and exposures of fluconazole, anidulafungin, and caspofungin in intensive care unit patients: Data from multinational Defining Antibiotic Levels in Intensive care unit (DALI) patients Study

scientific article

Pleiotropic Odorant-Binding Proteins Promote Aedes aegypti Reproduction and Flavivirus Transmission

scientific article published in 2021

Polymorphisms detected by random PCR distinguish between different chromosomal forms of Anopheles gambiae.

scientific article published in October 1994

Prostaglandins regulate humoral immune responses in Aedes aegypti

scientific article published on 23 October 2020

Protocol for Dengue Infections in Mosquitoes (A. aegypti) and Infection Phenotype Determination

scientific article (publication date: 2007)

Protocol for Plasmodium falciparum infections in mosquitoes and infection phenotype determination

scientific article published on 4 July 2007

Protocol for RNAi assays in adult mosquitoes (A. gambiae)

scientific article published on 4 July 2007

Protocol for mosquito rearing (A. gambiae).

scientific article published on 4 July 2007

Reciprocal tripartite interactions between the Aedes aegypti midgut microbiota, innate immune system and dengue virus influences vector competence

scientific article

Recombinant human erythropoietin therapy in critically ill patients: a dose-response study [ISRCTN48523317].

scientific article

Regulation of sexual development of Plasmodium by translational repression

scientific article

SOAP, a novel malaria ookinete protein involved in mosquito midgut invasion and oocyst development

scientific article (publication date: July 2003)

Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics

scientific article

Short- versus long-course antibacterial therapy for community-acquired pneumonia : a meta-analysis

scientific article

Spatial and sex-specific dissection of the Anopheles gambiae midgut transcriptome

scientific article

Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors

scientific article

The Aedes aegypti Toll Pathway Controls Dengue Virus Infection

scientific article

The Aedes aegypti siRNA pathway mediates broad-spectrum defense against human pathogenic viruses and modulates antibacterial and antifungal defenses

scientific article published on 09 June 2022

The Anopheles innate immune system in the defense against malaria infection

scientific article published on 28 August 2013

The Golgi associated ERI3 is a Flavivirus host factor

scientific article

The Gram-negative bacteria-binding protein gene family: its role in the innate immune system of anopheles gambiae and in anti-Plasmodium defence

scientific article published on February 2008

The Toll immune signaling pathway control conserved anti-dengue defenses across diverse Ae. aegypti strains and against multiple dengue virus serotypes

scientific article

The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line

scientific article published on August 2004

The entomopathogenic fungus Beauveria bassiana activate toll and JAK-STAT pathway-controlled effector genes and anti-dengue activity in Aedes aegypti

scientific article

The intensive care medicine research agenda on multidrug-resistant bacteria, antibiotics, and stewardship.

scientific article

The mosquito adulticidal Chromobacterium sp. Panama causes transgenerational impacts on fitness parameters and elicits xenobiotic gene responses.

scientific article published on 5 April 2018

The role of reactive oxygen species on Plasmodium melanotic encapsulation in Anopheles gambiae

scientific article

Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence

scientific article

Transcript Profiles ofBlumeria graminisDevelopment During Infection Reveal a Cluster of Genes That Are Potential Virulence Determinants

scientific article published on 01 February 2005

Transcriptional mediators Kto and Skd are involved in the regulation of the IMD pathway and anti-Plasmodium defense in Anopheles gambiae

scientific article

Transcriptome analysis of Aedes aegypti transgenic mosquitoes with altered immunity

scientific article

Transcriptome analysis of Anopheles stephensi-Plasmodium berghei interactions.

scientific article published on 12 April 2005

Transcriptome profiling of sexual maturation and mating in the Mediterranean fruit fly, Ceratitis capitata

scientific article

Transcriptomic and functional analysis of the Anopheles gambiae salivary gland in relation to blood feeding

scientific article

Transcriptomic profiling of diverse Aedes aegypti strains reveals increased basal-level immune activation in dengue virus-refractory populations and identifies novel virus-vector molecular interactions

scientific article

Trapping cDNAs encoding secreted proteins from the salivary glands of the malaria vector Anopheles gambiae.

scientific article

Trypsin-like Inhibitor Domain (TIL)-Harboring Protein Is Essential for Aedes aegypti Reproduction

scientific article published in 2022

Understanding resistance in Pseudomonas

scientific article published on 20 January 2020

Universal features of post-transcriptional gene regulation are critical for Plasmodium zygote development

scientific article (publication date: 12 February 2010)

Versatile transgenic multistage effector-gene combinations for Plasmodium falciparum suppression in Anopheles

scientific article published on 13 May 2020

Wolbachia invades Anopheles stephensi populations and induces refractoriness to Plasmodium infection

scientific article

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