List of works - Shu-wha Lin

A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia

scientific article published on 18 November 2015

A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner

scientific article

A knock-in Npm1 mutation in mice results in myeloproliferation and implies a perturbation in hematopoietic microenvironment

scientific article

A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia

scientific article (publication date: October 2003)

A novel thromboxane receptor antagonist, nstpbp5185, inhibits platelet aggregation and thrombus formation in animal models

scientific article published on 12 May 2016

A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells

scientific article published in 2014

Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia

scientific article published on 16 December 2011

Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4.

scientific article published on 26 October 2016

Cloning and characterization of cDNA clones corresponding to transcripts from the BamHI G region of the Epstein-Barr virus genome and expression of BGLF2.

scientific article

Current animal models of hemophilia: the state of the art

scientific article

Decreased expressions of hepsin in human hepatocellular carcinomas

scientific article published on September 2006

Differences in the pathogenicity of the p.H723R mutation of the common deafness-associated SLC26A4 gene in humans and mice

scientific article

Discontinuous residues of factor IX constitute a surface for binding the anti-factor IX monoclonal antibody A-5.

scientific article published in January 2003

Domain specific monoclonal anti-factor VIII antibodies generated by inclusion body-renatured factor VIII peptides

scientific article published in March 2001

Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells

scientific article published on 01 July 2019

Engineered recombinant factor VII Q217 variants with altered inhibitor specificities.

scientific article published on August 1999

Enhanced LPS-induced peritonitis in mice deficiency of cullin 4B in macrophages

scientific article

Epitope mapping of factor VIII inhibitor antibodies of Chinese origin

scientific article

FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis

scientific article

Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development

scientific article

Functional importance of apolipoprotein A5 185G in the activation of lipoprotein lipase.

scientific article

Genetic alterations at the splice junction of p53 gene in human hepatocellular carcinoma

scientific article published on 01 January 1994

Hepatocyte-Like Cells Derived From Mouse Induced Pluripotent Stem Cells Produce Functional Coagulation Factor IX in a Hemophilia B Mouse Model.

scientific article

IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan

scientific article

Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa.

scientific article published on 17 April 2002

Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated platelets.

scientific article published on 24 August 2004

Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome

scientific article

Impaired thrombin generation in Reelin-deficient mice: a potential role of plasma Reelin in hemostasis

scientific article published on 15 October 2014

Incorporation of the factor IX Padua mutation into FIX-Triple improves clotting activity in vitro and in vivo

scientific article published on 16 May 2013

Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice.

scientific article published on 18 January 2015

Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon.

scientific article published on January 2014

L2dtl is essential for cell survival and nuclear division in early mouse embryonic development

scientific article published on 15 November 2006

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy

scientific article

Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice

scientific article published on 9 February 2018

Mitochondrial genomic instability in colorectal cancer: no correlation to nuclear microsatellite instability and allelic deletion of hMSH2, hMLH1, and p53 genes, but prediction of better survival for Dukes' stage C disease

scientific article published on 07 July 2009

Monitoring liver function among patients who initiated anti-tuberculosis drugs in Taiwan, 2000-2011.

scientific article published on October 2014

Monocytic thrombomodulin triggers LPS- and gram-negative bacteria-induced inflammatory response.

scientific article published on 9 May 2012

Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway

scientific article published on 24 March 2017

SEPT12-microtubule complexes are required for sperm head and tail formation

scientific article

SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia

scientific article published on 01 July 2003

SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction

scientific article

Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice

scientific article published on 9 October 2012

Sun1 deficiency leads to cerebellar ataxia in mice

scientific article published on 5 May 2015

The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitors

scientific article

The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway

scientific article published on 12 March 2018

The expression level of septin12 is critical for spermiogenesis

scientific article

Tissue factor activity of SW-480 human colon adenocarcinoma cells is modulated by thrombin and protein kinase C activation.

scientific article

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

scientific article (publication date: 1987)

List of works by Shu-wha Lin

A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia

A Single miRNA-mRNA Interaction Affects the Immune Response in a Context- and Cell-Type-Specific Manner

A knock-in Npm1 mutation in mice results in myeloproliferation and implies a perturbation in hematopoietic microenvironment

A novel genetic variant in the apolipoprotein A5 gene is associated with hypertriglyceridemia

A novel thromboxane receptor antagonist, nstpbp5185, inhibits platelet aggregation and thrombus formation in animal models

A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells

Absence of biallelic TCRγ deletion predicts induction failure and poorer outcomes in childhood T-cell acute lymphoblastic leukemia

Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4.

Cloning and characterization of cDNA clones corresponding to transcripts from the BamHI G region of the Epstein-Barr virus genome and expression of BGLF2.

Current animal models of hemophilia: the state of the art

Decreased expressions of hepsin in human hepatocellular carcinomas

Differences in the pathogenicity of the p.H723R mutation of the common deafness-associated SLC26A4 gene in humans and mice

Discontinuous residues of factor IX constitute a surface for binding the anti-factor IX monoclonal antibody A-5.

Domain specific monoclonal anti-factor VIII antibodies generated by inclusion body-renatured factor VIII peptides

Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells

Engineered recombinant factor VII Q217 variants with altered inhibitor specificities.

Enhanced LPS-induced peritonitis in mice deficiency of cullin 4B in macrophages

Epitope mapping of factor VIII inhibitor antibodies of Chinese origin

FIX-Triple, a gain-of-function factor IX variant, improves haemostasis in mouse models without increased risk of thrombosis

Functional and structural deficits of the dentate gyrus network coincide with emerging spontaneous seizures in an Scn1a mutant Dravet Syndrome model during development

Functional importance of apolipoprotein A5 185G in the activation of lipoprotein lipase.

Genetic alterations at the splice junction of p53 gene in human hepatocellular carcinoma

Hepatocyte-Like Cells Derived From Mouse Induced Pluripotent Stem Cells Produce Functional Coagulation Factor IX in a Hemophilia B Mouse Model.

IKZF1 deletions predict a poor prognosis in children with B-cell progenitor acute lymphoblastic leukemia: a multicenter analysis in Taiwan

Identification of functionally important residues of the epidermal growth factor-2 domain of factor IX by alanine-scanning mutagenesis. Residues Asn(89)-Gly(93) are critical for binding factor VIIIa.

Identification of residues Asn89, Ile90, and Val107 of the factor IXa second epidermal growth factor domain that are essential for the assembly of the factor X-activating complex on activated platelets.

Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome

Impaired thrombin generation in Reelin-deficient mice: a potential role of plasma Reelin in hemostasis

Incorporation of the factor IX Padua mutation into FIX-Triple improves clotting activity in vitro and in vivo

Increased neutrophil infiltration, IL-1 production and a SAPHO syndrome-like phenotype in PSTPIP2-deficient mice.

Inhibition of miR-146a prevents enterovirus-induced death by restoring the production of type I interferon.

L2dtl is essential for cell survival and nuclear division in early mouse embryonic development

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy

Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice

Mitochondrial genomic instability in colorectal cancer: no correlation to nuclear microsatellite instability and allelic deletion of hMSH2, hMLH1, and p53 genes, but prediction of better survival for Dukes' stage C disease

Monitoring liver function among patients who initiated anti-tuberculosis drugs in Taiwan, 2000-2011.

Monocytic thrombomodulin triggers LPS- and gram-negative bacteria-induced inflammatory response.

Resveratrol attenuates ICAM-1 expression and monocyte adhesiveness to TNF-α-treated endothelial cells: evidence for an anti-inflammatory cascade mediated by the miR-221/222/AMPK/p38/NF-κB pathway

SEPT12-microtubule complexes are required for sperm head and tail formation

SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia

SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction

Serine protease hepsin regulates hepatocyte size and hemodynamic retention of tumor cells by hepatocyte growth factor signaling in mice

Sun1 deficiency leads to cerebellar ataxia in mice

The distinct roles that Gln-192 and Glu-217 of factor IX play in selectivity for macromolecular substrates and inhibitors

The effects of wild bitter gourd fruit extracts on ICAM-1 expression in pulmonary epithelial cells of C57BL/6J mice and microRNA-221/222 knockout mice: Involvement of the miR-221/-222/PI3K/AKT/NF-κB pathway

The expression level of septin12 is critical for spermiogenesis

Tissue factor activity of SW-480 human colon adenocarcinoma cells is modulated by thrombin and protein kinase C activation.

Vectors for selective expression of cloned DNAs by T7 RNA polymerase