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List of works by Ignacio Lizasoain

A Mouse Model of Hemorrhagic Transformation by Delayed Tissue Plasminogen Activator Administration After In Situ Thromboembolic Stroke

scientific article published on 24 November 2010

A chronic treatment with CDP-choline improves functional recovery and increases neuronal plasticity after experimental stroke.

scientific article

Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice

scientific article published on 25 February 2019

Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke.

scientific article

Activity of inducible and neuronal nitric oxide synthases in colonic mucosa predicts progression of ulcerative colitis.

scientific article

Aging increases microglial proliferation, delays cell migration, and decreases cortical neurogenesis after focal cerebral ischemia.

scientific article published on 10 May 2015

AhR Deletion Promotes Aberrant Morphogenesis and Synaptic Activity of Adult-Generated Granule Neurons and Impairs Hippocampus-Dependent Memory

scientific article published on 01 July 2018

Amelioration of ischemic brain damage by peritoneal dialysis.

scientific article published on 3 September 2013

Aspirin inhibits stress-induced increase in plasma glutamate, brain oxidative damage and ATP fall in rats

scientific article (publication date: 11 February 2002)

Buprenorphine: bell-shaped dose-response curve for its antagonist effects

scientific article published in January 1991

Calcium channel blockers: effect on morphine-induced hypermotility

scientific article published in January 1990

Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke

scientific article published on 29 November 2016

Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection

scientific article published on 20 October 2011

Cannabinoids: well-suited candidates for the treatment of perinatal brain injury.

scientific article published on 10 July 2013

Cerebrospinal fluid and plasma concentrations of nitric oxide metabolites are increased in dementia with Lewy bodies.

scientific article published in November 2002

Changes induced by sodium cromoglycate on brain serotonin turnover in morphine dependent and abstinent mice

scientific article published in January 1993

Characterization of Gcf2/Lrrfip1 in experimental cerebral ischemia and its role as a modulator of Akt, mTOR and β-catenin signaling pathways.

scientific article published on 14 March 2014

Characterization of the neuroprotective effect of the cannabinoid agonist WIN-55212 in an in vitro model of hypoxic-ischemic brain damage in newborn rats

scientific article published in August 2006

Chronic Stress Induces the Expression of Inducible Nitric Oxide Synthase in Rat Brain Cortex

scientific article published on 01 February 2000

Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke.

scientific article published on 13 May 2013

Colonic bacterial translocation as a possible factor in stress-worsening experimental stroke outcome.

scientific article published on 4 February 2009

Complexity of the cell-cell interactions in the innate immune response after cerebral ischemia

scientific article

Correlation between brain nitric oxide synthase activity and opiate withdrawal

scientific article published on February 1996

Daidzein has neuroprotective effects through ligand-binding-independent PPARγ activation

scientific article published on 11 April 2012

Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke.

scientific article published on 21 August 2007

Down-regulation of neuronal nitric oxide synthase by nitric oxide after oxygen-glucose deprivation in rat forebrain slices.

scientific article

Dual role of nitric oxide in adult neurogenesis

scientific article published on 20 April 2005

Effect of subacute and chronic immobilisation stress on the outcome of permanent focal cerebral ischaemia in rats

scientific article

Effects of antihistaminics on naloxone-induced withdrawal in morphine-dependent mice

scientific article published in January 1990

Effects of trepelennamine on brain monoamine turnover in morphine dependent and abstinent mice

scientific article published in February 1996

Efficacy of Alteplase in a Mouse Model of Acute Ischemic Stroke: A Retrospective Pooled Analysis

scientific article published on 31 March 2016

Expression and function of tumour necrosis factor-alpha-converting enzyme in the central nervous system

scientific article

Fructose-1,6-bisphosphate inhibits the expression of inducible nitric oxide synthase caused by oxygen-glucose deprivation through the inhibition of glutamate release in rat forebrain slices

scientific article published on 01 September 2000

Functional cGMP-gated channels in cerebellar granule cells

scientific journal article

Glutathione depletion, lipid peroxidation and mitochondrial dysfunction are induced by chronic stress in rat brain

scientific article

High blood pressure and inflammation are associated with poor prognosis in lacunar infarctions

scientific article

Hyperthermia is a surrogate marker of inflammation-mediated cause of brain damage in acute ischaemic stroke.

scientific article

Imaging the role of toll-like receptor 4 on cell proliferation and inflammation after cerebral ischemia by positron emission tomography

scientific article published on 19 January 2016

Immature rat brain slices exposed to oxygen-glucose deprivation as an in vitro model of neonatal hypoxic-ischemic encephalopathy

scientific article published in June 2005

Implication of Glutamate in the Expression of Inducible Nitric Oxide Synthase After Oxygen and Glucose Deprivation in Rat Forebrain Slices

scientific article published on 01 May 2000

Implication of TNF-alpha convertase (TACE/ADAM17) in inducible nitric oxide synthase expression and inflammation in an experimental model of colitis

scientific journal article

Implication of the Toll-like receptor 4 pathway in the response to interferon-β in multiple sclerosis.

scientific article

In vitro ischemic tolerance involves upregulation of glutamate transport partly mediated by the TACE/ADAM17-tumor necrosis factor-alpha pathway.

scientific article published in February 2004

Increased plasma levels of 15-deoxyDelta prostaglandin J2 are associated with good outcome in acute atherothrombotic ischemic stroke

scientific article published on 5 May 2005

Inducible nitric oxide synthase activity is expressed not only in inflamed but also in normal colonic mucosa in patients with ulcerative colitis: a potential prognostic marker

scientific article published on 01 May 2000

Induction of calcium-dependent nitric oxide synthases by sex hormones.

scientific article

Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain.

scientific article

Influence of psychogenetics in opiate tolerance and abstinence in mice

scientific article published on 01 January 1991

Inhibition by lamotrigine of the generation of nitric oxide in rat forebrain slices

scientific article published on 01 February 1995

Inhibition of glutamate release via recovery of ATP levels accounts for a neuroprotective effect of aspirin in rat cortical neurons exposed to oxygen-glucose deprivation

scientific article (publication date: 2002)

Inhibition of iNOS activity by 1400W decreases glutamate release and ameliorates stroke outcome after experimental ischemia

scientific article

Inhibition of morphine withdrawal by lamotrigine: involvement of nitric oxide.

scientific article published in March 1996

Involvement of IL-1beta in acute stress-induced worsening of cerebral ischaemia in rats

scientific article published on 23 March 2007

Iron Overload Exacerbates the Risk of Hemorrhagic Transformation After tPA (Tissue-Type Plasminogen Activator) Administration in Thromboembolic Stroke Mice

scientific article published on 01 September 2018

Iron overload, measured as serum ferritin, increases brain damage induced by focal ischemia and early reperfusion.

scientific article published on 2 October 2012

Iron-loaded transferrin (Tf) is detrimental whereas iron-free Tf confers protection against brain ischemia by modifying blood Tf saturation and subsequent neuronal damage

scientific article published on 2 December 2017

Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection.

scientific article published on 10 January 2007

Ischemic preconditioning: a novel target for neuroprotective therapy

scientific article published on 2 May 2006

L-kynurenine/aryl hydrocarbon receptor pathway mediates brain damage after experimental stroke.

scientific article published on 30 October 2014

Lack of adrenomedullin, but not complement factor H, results in larger infarct size and more extensive brain damage in a focal ischemia model.

scientific article

Longitudinal studies of ischemic penumbra by using 18 F-FDG PET and MRI techniques in permanent and transient focal cerebral ischemia in rats

scientific article published on 28 April 2011

Mechanisms of the neuroprotective effect of aspirin after oxygen and glucose deprivation in rat forebrain slices

scientific article published on 01 April 2000

Micro- and macroalbuminuria predict hemorrhagic transformation in acute ischemic stroke.

scientific article published in October 2006

Mitochondria and reactive oxygen and nitrogen species in neurological disorders and stroke: Therapeutic implications.

scientific article published on 27 August 2009

Mitochondrial respiratory chain and free radical generation in stroke.

scientific article

Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa.

scientific article

Morphine-induced changes in cerebral and cerebellar nitric oxide synthase activity

scientific article published on 01 October 1995

Myeloid cells as therapeutic targets in neuroinflammation after stroke: Specific roles of neutrophils and neutrophil-platelet interactions

scientific article published on 21 August 2018

N-(3-(aminomethyl)benzyl)acetamidine, an inducible nitric oxide synthase inhibitor, decreases colonic inflammation induced by trinitrobenzene sulphonic acid in rats.

scientific article published in June 2001

N2 neutrophils, novel players in brain inflammation after stroke: modulation by the PPARγ agonist rosiglitazone.

scientific article

Neuronal and inducible nitric oxide synthase and nitrotyrosine immunoreactivities in the cerebral cortex of the aging rat.

scientific article published in October 1998

Neuronal death induced by SIN-1 in the presence of superoxide dismutase: protection by cyclic GMP.

scientific article published in August 1998

Neuronal excitotoxicity after carotid angioplasty and stent placement procedures

scientific article published on 22 March 2013

Neuronal expression of inducible nitric oxide synthase after oxygen and glucose deprivation in rat forebrain slices.

scientific article published in February 1998

Neuroprotection afforded by prior citicoline administration in experimental brain ischemia: effects on glutamate transport

scientific article

Neuroprotection and recovery: recent data at the bench on citicoline.

scientific article

Neuroprotective effect of aspirin by inhibition of glutamate release after permanent focal cerebral ischaemia in rats

scientific article (publication date: October 2001)

Neuroprotective effects of DETA-NONOate, a nitric oxide donor, on hydrogen peroxide-induced neurotoxicity in cortical neurones

scientific article published in September 1999

Neuroprotective effects of aspirin in patients with acute cerebral infarction

scientific article (publication date: 27 March 2003)

Neurorepair versus neuroprotection in stroke.

scientific article published on 2 May 2006

Neutrophils scan for activated platelets to initiate inflammation.

scientific article published on 4 December 2014

New-onset hypertension and inflammatory response/poor outcome in acute ischemic stroke.

scientific article published in December 2006

Nitric oxide synthase activity in human squamous cell carcinoma of the head and neck

scientific article published on 01 January 1999

Oct-2 transcription factor binding activity and expression up-regulation in rat cerebral ischaemia is associated with a diminution of neuronal damage in vitro.

scientific article published on 27 November 2013

Peroxisome proliferator-activated receptor gamma activation decreases neuroinflammation in brain after stress in rats

scientific journal article

Plasma levels of 15d-PGJ2are not altered in multiple sclerosis

scientific article published on 15 June 2009

Preliminary research on 1-(4-bromo-2-nitroimidazol-1-yl)-3-[(18)F]fluoropropan-2-ol as a novel brain hypoxia PET tracer in a rodent model of stroke.

scientific article published on 12 June 2015

Protective effect of N-(3-(aminomethyl)benzyl) acetamidine, an inducible nitric oxide synthase inhibitor, in brain slices exposed to oxygen-glucose deprivation

scientific article published in August 1998

Rational modulation of the innate immune system for neuroprotection in ischemic stroke

scientific article

Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke ⬇️

scientific article published on January 12, 2012

Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress

scientific article published in September 2003

Reparative effects of interleukin-1 receptor antagonist in young and aged/co-morbid rodents after cerebral ischemia

scientific article published on 14 November 2016

Role of K+ and Ca2+ fluxes in the cerebroarterial vasoactive effects of sildenafil.

scientific article published on 28 November 2007

Role of nitric oxide after brain ischaemia

scientific article

Role of sodium cromoglycate on analgesia, locomotor activity and opiate withdrawal in mice

scientific article published on 01 January 1992

Rosiglitazone and 15-deoxy-Delta12,14-prostaglandin J2 cause potent neuroprotection after experimental stroke through noncompletely overlapping mechanisms.

scientific article published in February 2006

Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways.

scientific article published on 12 December 2013

Seladin-1/DHCR24 Is Neuroprotective by Associating EAAT2 Glutamate Transporter to Lipid Rafts in Experimental Stroke.

scientific article published in December 2015

Silent information regulator 1 protects the brain against cerebral ischemic damage

scientific article published on 30 May 2013

Specific Features of SVZ Neurogenesis After Cortical Ischemia: a Longitudinal Study

scientific article published on 27 November 2017

Statin treatment withdrawal in ischemic stroke: a controlled randomized study

scientific article published in August 2007

Stereological and flow cytometry characterization of leukocyte subpopulations in models of transient or permanent cerebral ischemia.

scientific article published on 28 December 2014

Stress increases susceptibility to oxidative/nitrosative mucosal damage in an experimental model of colitis in rats.

scientific article published in October 2004

Stress-induced increase in extracellular sucrose space in rats is mediated by nitric oxide

scientific article published in May 2002

Synthesis of lipoxin A4 by 5-lipoxygenase mediates PPARgamma-dependent, neuroprotective effects of rosiglitazone in experimental stroke.

scientific article published in March 2009

TLR4-Binding DNA Aptamers Show a Protective Effect against Acute Stroke in Animal Models

scientific article published on 15 June 2018

TNF-alpha accounts for short-term persistence of oxidative status in rat brain after two weeks of repeated stress.

scientific article

TNF-alpha converting enzyme (TACE) protein expression in different clinical subtypes of multiple sclerosis

scientific article published on 6 March 2006

TNFR1 mediates increased neuronal membrane EAAT3 expression after in vivo cerebral ischemic preconditioning.

scientific article published on 25 January 2006

TNFR1 upregulation mediates tolerance after brain ischemic preconditioning.

scientific article

Targets of cytoprotection in acute ischemic stroke: present and future.

scientific article published on 2 May 2006

Test repositioning for functional assessment of neurological outcome after experimental stroke in mice

scientific article

The Increase of Circulating Endothelial Progenitor Cells After Acute Ischemic Stroke Is Associated With Good Outcome

scientific article published on 30 August 2007

The Role of PPARγ on Restoration of Colonic Homeostasis After Experimental Stress-Induced Inflammation and Dysfunction

scientific article published on 21 February 2007

The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats.

scientific article

The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia.

scientific article published on December 2010

The cannabinoid agonist WIN55212 reduces brain damage in an in vivo model of hypoxic-ischemic encephalopathy in newborn rats.

scientific article

The high-mobility group I-Y transcription factor is involved in cerebral ischemia and modulates the expression of angiogenic proteins.

scientific article

The increase in TNF-alpha levels is implicated in NF-kappaB activation and inducible nitric oxide synthase expression in brain cortex after immobilization stress.

scientific article published in February 2002

The ontogeny of cerebral and cerebellar nitric oxide synthase in the guinea pig and rat

scientific article published on 01 May 1996

The prediction of malignant cerebral infarction by molecular brain barrier disruption markers.

scientific article published on 11 August 2005

The release of tumor necrosis factor-α is associated with ischemic tolerance in human stroke

scientific article published on 01 December 2003

The role of tumor necrosis factor-alpha in stress-induced worsening of cerebral ischemia in rats

scientific article published on 17 July 2006

The seek of neuroprotection: introducing cannabinoids.

scientific article published on June 2007

Toll-Like Receptor 4 Mediates Hemorrhagic Transformation After Delayed Tissue Plasminogen Activator Administration in In Situ Thromboembolic Stroke

scientific article published on 20 April 2017

Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke.

scientific article published on 19 March 2007

Toll-like receptor 4 is involved in neuroprotection afforded by ischemic preconditioning

scientific article published on 7 February 2009

Toll-like receptor 4 is involved in subacute stress-induced neuroinflammation and in the worsening of experimental stroke

scientific article

Toll-like receptor 4 modulates cell migration and cortical neurogenesis after focal cerebral ischemia.

scientific article published on 25 July 2014

Toll-like receptor 4 regulates subventricular zone proliferation and neuroblast migration after experimental stroke

scientific article published on 03 May 2019

Up-regulation of TNF-alpha convertase (TACE/ADAM17) after oxygen-glucose deprivation in rat forebrain slices

scientific article published in June 2001

Upregulation of TACE/ADAM17 after ischemic preconditioning is involved in brain tolerance

scientific article published in November 2002

Use of brain slices in the study of pathogenic role of inducible nitric oxide synthase in cerebral ischemia-reperfusion.

scientific article

Validation of housekeeping genes for quantitative real-time PCR in in-vivo and in-vitro models of cerebral ischaemia

scientific article published on 16 June 2009

[Increased expression and activity of MMP-9 in chronic rhinosinusitis with nasal polyposis]

scientific article published on 01 November 2008

[The cannabinoid system and its importance in the perinatal period]

cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.

scientific article published on February 1996

miRNA expression is modulated over time after focal ischaemia: up-regulation of miR-347 promotes neuronal apoptosis

scientific article

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