List of works - Markus Welcker

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

scientific article published in October 2004

Cell cycle: how cyclin E got its groove back

scientific article

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

scientific article published on June 2008

Enhanced protein stability: a novel mechanism of D-type cyclin over-abundance identified in human sarcoma cells

scientific article published on 01 July 1996

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

scientific article

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

scientific article (publication date: February 2008)

Fbw7 dimerization determines the specificity and robustness of substrate degradation.

scientific article published on December 2013

Fbw7/hCDC4 dimerization regulates its substrate interactions

scientific article published on 13 February 2007

Identification of CDK2 substrates in human cell lysates

scientific article published on 13 October 2008

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase

scientific article

Kinase-independent function of cyclin E

scientific article published on 01 January 2007

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

scientific article (publication date: August 2003)

Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3.

scientific article

Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase

scientific article

Rapid destruction of human Cdc25A in response to DNA damage

scientific journal article

Ras activity regulates cyclin E degradation by the Fbw7 pathway.

scientific article

Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

scientific article published on 13 September 2004

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

scholarly article

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.

scientific article

Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma

scientific article published on 14 July 2008

Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins

scientific journal article

p21/WAF1/Cip1 expression in invasive ductal breast carcinoma: relationship to p53, proliferation rate, and survival at 5 years

scientific article published on 01 August 2001

p21WAF1/CIP1 mutants deficient in inhibiting cyclin-dependent kinases (CDKs) can promote assembly of active cyclin D/CDK4(6) complexes in human tumor cells

scientific article published on 01 November 1998

p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability.

scientific article

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation

scientific article published in October 2002

List of works by Markus Welcker

A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

Cell cycle: how cyclin E got its groove back

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

Enhanced protein stability: a novel mechanism of D-type cyclin over-abundance identified in human sarcoma cells

FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to gamma-secretase inhibitors

FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

Fbw7 dimerization determines the specificity and robustness of substrate degradation.

Fbw7/hCDC4 dimerization regulates its substrate interactions

Identification of CDK2 substrates in human cell lysates

Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase

Kinase-independent function of cyclin E

Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation

Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3.

Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase

Rapid destruction of human Cdc25A in response to DNA damage

Ras activity regulates cyclin E degradation by the Fbw7 pathway.

Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation

The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.

Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma

Zcchc8 is a glycogen synthase kinase-3 substrate that interacts with RNA-binding proteins

p21/WAF1/Cip1 expression in invasive ductal breast carcinoma: relationship to p53, proliferation rate, and survival at 5 years

p21WAF1/CIP1 mutants deficient in inhibiting cyclin-dependent kinases (CDKs) can promote assembly of active cyclin D/CDK4(6) complexes in human tumor cells

p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability.

p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation