List of works - Moritz Gerstung

A High-Density Map for Navigating the Human Polycomb Complexome

scientific journal article

A high density map for navigating the human Polycomb complexome

A quantitative and dynamic model for plant stem cell regulation

scientific article

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

scientific article published on 6 December 2017

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.

scientific article published on 22 May 2018

Biallelic mutations in cancer genomes reveal local mutational determinants

scientific article published on 10 February 2022

C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation

scientific article published on 06 October 2021

Cancer evolution: mathematical models and computational inference

scientific article

Cell2location maps fine-grained cell types in spatial transcriptomics

scientific article published on 13 January 2022

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

scientific article published on 15 April 2021

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

article

Clinical and biological implications of driver mutations in myelodysplastic syndromes

scientific article published on 12 September 2013

Clinicopathological and prognostic implications of genetic alterations in oral cancers

scientific article

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

scientific article published on 01 December 2019

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

scientific article

Control of plant organ size by KLUH/CYP78A5-dependent intercellular signaling

scientific article published in December 2007

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on May 2016

Extensive heterogeneity in somatic mutation and selection in the human bladder

scientific article published on 01 October 2020

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

scientific article published on 11 May 2015

Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers

scientific article published on 10 November 2011

Genomic Classification and Prognosis in Acute Myeloid Leukemia

scientific article

Genomic Evolution of Breast Cancer Metastasis and Relapse

scientific article published on August 2017

Genomic copy number predicts esophageal cancer years before transformation

scientific article published on 07 September 2020

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

scientific article published on 23 August 2019

Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome

scientific article

Genomic reconstruction of the SARS-CoV-2 epidemic in England

scientific article

Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts

scientific article published on 27 August 2018

Immuno-oncology from the perspective of somatic evolution.

scientific article published on 6 December 2017

Kinetic, energetic, and mechanical differences between dark-state rhodopsin and opsin

scientific article published on 21 February 2013

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article

Learning mutational signatures and their multidimensional genomic properties with TensorSignatures

scientific article published on 15 June 2021

Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival

scientific article published on 23 July 2021

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

scientific article

Mutational signatures are jointly shaped by DNA damage and repair

scientific article published on 01 May 2020

Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers.

scientific article published on 10 April 2018

Neutral tumor evolution?

scientific article

Noisy signaling through promoter logic gates

scientific article published on 29 January 2009

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

scientific article

Polycomb preferentially targets stalled promoters of coding and noncoding transcripts

scientific article

Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types

Prediction of acute myeloid leukaemia risk in healthy individuals

scientific article published in Nature

Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation

scientific article published on 27 April 2021

Quantifying cancer progression with conjunctive Bayesian networks

scientific article published on 19 August 2009

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

scientific article

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

scientific article published on 01 November 2016

Reliable detection of subclonal single-nucleotide variants in tumour cell populations

scientific article published in May 2012

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

scientific article published on 05 October 2020

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

scientific article

Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium

scientific article published on 18 May 2020

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

scientific article published on 22 June 2015

Subclonal variant calling with multiple samples and prior knowledge

scientific article

The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila

scientific article

The evolutionary history of 2,658 cancers

The temporal order of genetic and pathway alterations in tumorigenesis

scientific article

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

scientific article

Universal Patterns Of Selection In Cancer And Somatic Tissues

Universal Patterns of Selection in Cancer and Somatic Tissues

scientific article published on 18 October 2017

Universal Patterns of Selection in Cancer and Somatic Tissues.

scientific article published in June 2018

List of works by Moritz Gerstung

A High-Density Map for Navigating the Human Polycomb Complexome

A high density map for navigating the human Polycomb complexome

A quantitative and dynamic model for plant stem cell regulation

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups

Analysis of the genomic landscape of multiple myeloma highlights novel prognostic markers and disease subgroups.

Biallelic mutations in cancer genomes reveal local mutational determinants

C. elegans genome-wide analysis reveals DNA repair pathways that act cooperatively to preserve genome integrity upon ionizing radiation

Cancer evolution: mathematical models and computational inference

Cell2location maps fine-grained cell types in spatial transcriptomics

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes

Classification and Personalized Prognosis in Myeloproliferative Neoplasms

Clinical and biological implications of driver mutations in myelodysplastic syndromes

Clinicopathological and prognostic implications of genetic alterations in oral cancers

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Control of plant organ size by KLUH/CYP78A5-dependent intercellular signaling

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Extensive heterogeneity in somatic mutation and selection in the human bladder

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Genome-wide expression and copy number analysis identifies driver genes in gingivobuccal cancers

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Genomic Evolution of Breast Cancer Metastasis and Relapse

Genomic copy number predicts esophageal cancer years before transformation

Genomic landscape and chronological reconstruction of driver events in multiple myeloma

Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome

Genomic reconstruction of the SARS-CoV-2 epidemic in England

Identification of Prognostic Phenotypes of Esophageal Adenocarcinoma in 2 Independent Cohorts

Immuno-oncology from the perspective of somatic evolution.

Kinetic, energetic, and mechanical differences between dark-state rhodopsin and opsin

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

Learning mutational signatures and their multidimensional genomic properties with TensorSignatures

Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Mutational signatures are jointly shaped by DNA damage and repair

Mutational signatures of DNA mismatch repair deficiency in C. elegans and human cancers.

Neutral tumor evolution?

Noisy signaling through promoter logic gates

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Polycomb preferentially targets stalled promoters of coding and noncoding transcripts

Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types

Prediction of acute myeloid leukaemia risk in healthy individuals

Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation

Quantifying cancer progression with conjunctive Bayesian networks

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

RUNX1 mutations in acute myeloid leukemia are associated with distinct clinico-pathologic and genetic features

Reliable detection of subclonal single-nucleotide variants in tumour cell populations

Somatic mutation distributions in cancer genomes vary with three-dimensional chromatin structure

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

Subclonal variant calling with multiple samples and prior knowledge

The BET protein FSH functionally interacts with ASH1 to orchestrate global gene activity in Drosophila

The evolutionary history of 2,658 cancers

The temporal order of genetic and pathway alterations in tumorigenesis

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

Universal Patterns Of Selection In Cancer And Somatic Tissues

Universal Patterns of Selection in Cancer and Somatic Tissues

Universal Patterns of Selection in Cancer and Somatic Tissues.