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List of works by Seishiro Hirano

A current overview of health effect research on nanoparticles

scientific article published on 18 March 2009

A murine scavenger receptor MARCO recognizes polystyrene nanoparticles

scientific article published on 14 March 2007

A new metabolic pathway of arsenite: arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19.

scientific article published on 4 November 2004

A novel genotoxicity assay of carbon nanotubes using functional macrophage receptor with collagenous structure (MARCO)-expressing chicken B lymphocytes

scientific article published on 21 August 2013

Aberrant expression of pRb and p16(INK4), alone or in combination, indicates poor outcome after resection in patients with colorectal carcinoma

scientific article published on 01 October 2004

Accumulation and toxicity of monophenyl arsenicals in rat endothelial cells

scientific article published on 11 September 2004

Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles.

scientific article

Analysis of arsenic metabolites in HepG2 and AS3MT-transfected cells

scientific article published on 3 May 2011

Arsenic metabolism and thioarsenicals in hamsters and rats

scientific article published on 24 March 2007

Arsenic speciation in bile and urine following oral and intravenous exposure to inorganic and organic arsenics in rats

scientific article published in September 2004

Arsenic speciation in the urine and hair of individuals exposed to airborne arsenic through coal-burning in Guizhou, PR China

scientific article

Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells.

scientific article published on March 2006

Benzalkonium chloride and cetylpyridinium chloride induce apoptosis in human lung epithelial cells and alter surface activity of pulmonary surfactant monolayers

scientific article published on 24 January 2020

Biotransformation of arsenic and toxicological implication of arsenic metabolites

scientific article published on 20 May 2020

Cellular distribution and behavior of metallothionein in mammalian cells following exposure to silver nanoparticles and silver ions

scientific article

Cellular uptake of paraquat determines subsequent toxicity including mitochondrial damage in lung epithelial cells

scientific article published on 22 November 2018

Characteristics and modifying factors of asbestos-induced oxidative DNA damage.

scientific article published on 4 September 2008

Characterization and influence of hydroxyapatite nanopowders on living cells

scientific article published on 27 December 2018

Characterization of dilution conditions for diesel nanoparticle inhalation studies

scientific article published in February 2009

Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice

scientific article published on 16 March 2006

Combined experimental and computational approach to developing efficient photocatalysts based on Au/Pd–TiO2 nanoparticles

Cytotoxic effects of S-(dimethylarsino)-glutathione: a putative intermediate metabolite of inorganic arsenicals

scientific article published on 14 July 2006

Developmental subchronic exposure to diphenylarsinic acid induced increased exploratory behavior, impaired learning behavior, and decreased cerebellar glutathione concentration in rats

scientific article

Difference in the toxicity mechanism between ion and nanoparticle forms of silver in the mouse lung and in macrophages

scientific article published on 16 December 2014

Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells

scientific article

Differential Regulation of IL-1β and IL-6 Release in Murine Macrophages

scientific article published in August 2017

Diphenylarsinic Acid Induced Activation of Cultured Rat Cerebellar Astrocytes: Phosphorylation of Mitogen-Activated Protein Kinases, Upregulation of Transcription Factors, and Release of Brain-Active Cytokines

scientific article published on 8 December 2015

Diphenylarsinic acid increased the synthesis and release of neuroactive and vasoactive peptides in rat cerebellar astrocytes

scientific article

Distribution and excretion of arsenic in cynomolgus monkey following repeated administration of diphenylarsinic acid.

scientific article published on 19 December 2007

Dysregulation of MAP Kinase Signaling Pathways Including p38MAPK, SAPK/JNK, and ERK1/2 in Cultured Rat Cerebellar Astrocytes Exposed to Diphenylarsinic Acid

scientific article published on 13 January 2017

Effects of PAMAM dendrimers in the mouse brain after a single intranasal instillation

scientific article published on 9 May 2014

Effects of PAMAM dendrimers with various surface functional groups and multiple generations on cytotoxicity and neuronal differentiation using human neural progenitor cells

scientific article published in January 2016

Effects of acute single intranasal instillation of secondary organic aerosol on neurological and immunological biomarkers in the brain and lung of BALB/c mice

scientific article published on February 2013

Effects of airway exposure to nanoparticles on lung inflammation induced by bacterial endotoxin in mice

scientific article

Effects of arsenic on modification of promyelocytic leukemia (PML): PML responds to low levels of arsenite

scientific article published on 14 October 2013

Effects of arsenic on the topology and solubility of promyelocytic leukemia (PML)-nuclear bodies

scientific article published on 20 May 2022

Effects of diesel engine exhaust origin secondary organic aerosols on novel object recognition ability and maternal behavior in BALB/c mice

scientific article

Effects of diesel exhaust-derived secondary organic aerosol (SOA) on oocytes: Potential risks to meiotic maturation

scientific article published on 17 November 2017

Effects of eicosane, a component of nanoparticles in diesel exhaust, on surface activity of pulmonary surfactant monolayers

scientific article published on 17 May 2008

Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile

scientific article published on 21 June 2008

Effects of exposure to nanoparticle-rich diesel exhaust on 8-OHdG synthesis in the mouse asthmatic lung

scientific article

Effects of exposure to nanoparticle-rich or -depleted diesel exhaust on allergic pathophysiology in the murine lung

scientific article published on 01 February 2013

Effects of inhaled nanoparticles on acute lung injury induced by lipopolysaccharide in mice

scientific article published on 2 June 2007

Effects of multi-walled carbon nanotubes on a murine allergic airway inflammation model

scientific article

Effects of nanoparticle-rich diesel exhaust particles on IL-17 production in vitro

scientific article published in January 2012

Effects of organic chemicals derived from ambient particulate matter on lung inflammation related to lipopolysaccharide

scientific article

Effects of phytoestrogens and environmental estrogens on osteoblastic differentiation in MC3T3-E1 cells

scientific article published on March 2004

Effects of the phytoestrogen coumestrol on RANK-ligand-induced differentiation of osteoclasts

scientific article published on October 2004

Evaluating the toxicity of TiO2-based nanoparticles to Chinese hamster ovary cells and Escherichia coli: a complementary experimental and computational approach

scientific article

Exposure of BALB/c Mice to Diesel Engine Exhaust Origin Secondary Organic Aerosol (DE-SOA) during the Developmental Stages Impairs the Social Behavior in Adult Life of the Males

scientific article

Exposure to nanoparticle-rich diesel exhaust affects hippocampal functions in mice

scientific article published in September 2011

Expression and activity of arsenic methyltransferase Cyt19 in rat tissues

scientific article published on 04 August 2006

Extracellular glutamate level and NMDA receptor subunit expression in mouse olfactory bulb following nanoparticle-rich diesel exhaust exposure

scientific article published in August 2009

Extrapulmonary translocation of intratracheally instilled fine and ultrafine particles via direct and alveolar macrophage-associated routes

scientific article published on 25 October 2008

Generation of Airborne Multi-Walled Carbon Nanotubes for Inhalation Studies

journal article; published in Aerosol Science and Technology in 2009

Health effects of nanoparticles and nanomaterials (II) methods for measurement of nanoparticles and their presence in the air

scientific article published in May 2008

Identification of arsenite-and arsenic diglutathione-binding proteins in human hepatocarcinoma cells

scientific article published on 27 October 2009

In vitro effects of nanoparticle-rich diesel exhaust particles on splenic mononuclear cells.

scientific article published on 14 January 2011

In vitro study of the effect of nanoparticle-rich diesel exhaust particles on IL-18 production in splenocytes

scientific article published in January 2011

Induction of oxidative stress and inhibition of plasminogen activator inhibitor-1 production in endothelial cells following exposure to organic extracts of diesel exhaust particles and urban fine particles

scientific article

Iron overload signature in chrysotile-induced malignant mesothelioma

scientific article

Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway

scientific article

Macrophage receptor with collagenous structure (MARCO) is a dynamic adhesive molecule that enhances uptake of carbon nanotubes by CHO-K1 cells

scientific article published on 20 December 2011

Metabolism of arsenic and its toxicological relevance

scientific article published on 19 July 2012

Mitochondrial electron transport is inhibited by disappearance of metallothionein in human bronchial epithelial cells following exposure to silver nitrate

scientific article published on 17 January 2013

Multi-walled carbon nanotubes injure the plasma membrane of macrophages

scientific article

Nano-QSAR modeling for ecosafe design of heterogeneous TiO2-based nano-photocatalysts

scholarly article by Alicja Mikołajczyk et al published 2018 in Environmental science. Nano

Nano-Sized Secondary Organic Aerosol of Diesel Engine Exhaust Origin Impairs Olfactory-Based Spatial Learning Performance in Preweaning Mice

scientific article published on 30 June 2015

Nanoparticle-rich diesel exhaust affects hippocampal-dependent spatial learning and NMDA receptor subunit expression in female mice

scientific article published on 13 June 2011

Nasal instillation of nanoparticle-rich diesel exhaust particles slightly affects emotional behavior and learning capability in rats.

scientific article published in June 2011

Novel object recognition ability in female mice following exposure to nanoparticle-rich diesel exhaust

scientific article published in June 2012

Oxidative-stress potency of organic extracts of diesel exhaust and urban fine particles in rat heart microvessel endothelial cells

scientific article published on May 2003

PCR-based subtraction analyses for upregulated gene transcription in cadmium-exposed rat lung type 2 epithelial cells

scientific journal article

Perinatal Exposure to Diesel Exhaust-Origin Secondary Organic Aerosol Induces Autism-Like Behavior in Rats

journal article from 'International Journal of Molecular Sciences' published in 2021

Pharmacodynamics of S-dimethylarsino-glutathione, a putative metabolic intermediate of inorganic arsenic, in mice.

scientific article published on 23 November 2016

Promyelocytic leukemia nuclear body-like structures can assemble in mouse oocytes

scientific article published on 06 June 2022

Quantitative risk analysis of particulate matter in the air: interspecies extrapolation with bioassay and mathematical models

scientific article

Rapid speciation and quantification of selenium compounds by HPLC-ICP MS using multiple standards labelled with different isotopes

scientific article published on 15 July 2011

Regarding the special feature of "the frontline of nanoparticle research": progress of the Study Group on Fibrous and Particulate Substances (SGFPS)

scientific article

Relevance of autophagy markers to cytotoxicity of zinc compounds in macrophages

scientific article published on 29 February 2020

Repulsive Apoptosis During Exposure of Mesencephalic Neural Stem Cells to Silver Nanoparticles in a Neurosphere Assay In Vitro

scientific article

Role of TLR4 in olfactory-based spatial learning activity of neonatal mice after developmental exposure to diesel exhaust origin secondary organic aerosol

scientific article published on 26 October 2017

Scavenger receptor MARCO contributes to cellular internalization of exosomes by dynamin-dependent endocytosis and macropinocytosis

scientific article published on 11 December 2020

Seasonal differences of the atmospheric particle size distribution in a metropolitan area in Japan

scientific article published on 4 September 2012

Selective activation of NF-kappaB and E2F by low concentration of arsenite in U937 human monocytic leukemia cells

scientific article

Simultaneous analysis of cardiac glycosides in blood and urine by thermoresponsive LC-MS-MS

scientific article published on November 15, 2010

Solubility changes of promyelocytic leukemia (PML) and SUMO monomers and dynamics of PML nuclear body proteins in arsenite-treated cells

scientific article published on 05 October 2018

Solubility shift and SUMOylaltion of promyelocytic leukemia (PML) protein in response to arsenic(III) and fate of the SUMOylated PML.

scientific article published on 3 June 2015

Spatial learning and memory function-related gene expression in the hippocampus of mouse exposed to nanoparticle-rich diesel exhaust

scientific article

Speciation analysis of selenium metabolites in urine and breath by HPLC- and GC-inductively coupled plasma-MS after administration of selenomethionine and methylselenocysteine to rats

scientific article published in November 2009

Stability of arsenic metabolites, arsenic triglutathione [As(GS)3] and methylarsenic diglutathione [CH3As(GS)2], in rat bile

scientific article published in July 2005

Subchronic exposure to arsenic through drinking water alters expression of cancer-related genes in rat liver

scientific journal article

Sulfide induces apoptosis and Rho kinase-dependent cell blebbing in Jurkat cells

scientific article published on 12 March 2013

The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds

scientific article published in August 2004

The role of Rho-kinases in IL-1β release through phagocytosis of fibrous particles in human monocytes

scientific article published on 24 April 2014

The role of glutathione in the metabolism of diphenylarsinic acid in rats

scientific article published on 04 February 2013

The role of toll-like receptor 4 in airway inflammation induced by diesel exhaust particles.

scientific article published on 28 October 2005

The toxicological analysis of secondary organic aerosol in human lung epithelial cells and macrophages

scientific article published on 06 June 2019

Theoretical calculations and reaction analysis on the interaction of pentavalent thioarsenicals with biorelevant thiol compounds

scientific article published on 8 January 2008

Uptake and cytotoxic effects of multi-walled carbon nanotubes in human bronchial epithelial cells

scientific article published on 26 August 2010

Western blot analysis

scientific article published on 01 January 2012

[Environmental exposure to silver and its health effects]

scientific article published on 01 May 2012

cDNA microarray analysis of rat alveolar epithelial cells following exposure to organic extract of diesel exhaust particles

scientific article