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List of works by Christian Gege

A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models.

scientific article published in July 2009

Calcium-Dependent Carbohydrate-Carbohydrate Recognition between Lewis(X) Blood Group Antigens This research was supported by the Deutsche Forschungsgemeinschaft and the Fonds der Chemischen Industrie

scientific article published on 01 September 2000

Carbohydrate-Carbohydrate Recognition between LewisX Glycoconjugates

scientific article published on 01 May 1999

Closing the gap: identification of human 3-ketosteroid reductase, the last unknown enzyme of mammalian cholesterol biosynthesis

scientific journal article

Cooperation between lateral ligand mobility and accessibility for receptor recognition in selectin-induced cell rolling.

scientific article

Discovery and evaluation of a non-Zn chelating, selective matrix metalloproteinase 13 (MMP-13) inhibitor for potential intra-articular treatment of osteoarthritis

scientific article published on 10 January 2012

Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction

scientific article published on 26 September 2020

Frontiers in Medicinal Chemistry 2009--a summary of the meeting at Heidelberg University

scientific article published in August 2009

Functional microdomains of glycolipids with partially fluorinated membrane anchors: impact on cell adhesion

scientific article published in February 2004

Grazing-Incidence Neutron-Induced Fluorescence Probes Density Profiles of Labeled Molecules at Solid/Liquid Interfaces

scientific article published on 14 March 2013

Hydrophilic/Hydrophobic balance determines morphology of glycolipids with oligolactose headgroups

scientific article published on January 2003

Identification and biological evaluation of thiazole-based inverse agonists of RORγt

scientific article published on 3 April 2018

Identification of the first inverse agonist of retinoid-related orphan receptor (ROR) with dual selectivity for RORβ and RORγt

scientific article published on 28 September 2014

Knocking on FXR's door: the "hammerhead"-structure series of FXR agonists - amphiphilic isoxazoles with potent in vitro and in vivo activities

scientific article

Lessons learned from clustering of fluorinated glycolipids on selectin ligand function in cell rolling

scientific article published in March 2006

Membrane adhesion via homophilic saccharide-saccharide interactions investigated by neutron scattering

scientific article published on May 2011

Modulation of intermembrane interaction and bending rigidity of biomembrane models via carbohydrates investigated by specular and off-specular neutron scattering

scientific article published on 30 December 2008

Nonsteroidal FXR Ligands: Current Status and Clinical Applications

scientific article published on 01 January 2019

Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties

scientific article published on 24 May 2016

Oligomer-to-polymer transition in short ethylene glycol chains connected to mobile hydrophobic anchors

scientific article published in January 2005

RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345.

scientific article published on 17 November 2016

Retinoid-related orphan receptor gamma t (RORγt) inhibitors from Vitae Pharmaceuticals (WO2015116904) and structure proposal for their Phase I candidate VTP-43742.

scientific article published on 4 March 2016

Retinoid-related orphan receptor γ t modulators: comparison of Glenmark's me-too patent application (WO2015008234) with the originator application from Merck Sharp and Dohme (WO2012106995)

scientific article published on 09 July 2015

Structure-based design, synthesis and in vitro characterization of potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors based on 2-substitutions of estrone and D-homo-estrone

scientific article published on 3 October 2009

Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture

scientific article published on 18 May 2011

Synthesis of dimeric lactose and dimeric (sialyl) Lewis(X) glycolipids

scientific article

Total synthesis of the natural antigen involved in the hyperacute rejection response to xenotransplants

scientific article published on 01 October 2000

Visualization of sialyl Lewis(X) glycosphingolipid microdomains in model membranes as selectin recognition motifs using a fluorescence label.

scientific article

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