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List of works by Serge Van Calenbergh

1-(1-Arylethylpiperidin-4-yl)thymine Analogs as Antimycobacterial TMPK Inhibitors

scientific article published on 17 June 2020

2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F<sub>420</sub>)-Dependent Nitroreductase (Ddn)

scientific article published on 21 December 2020

2-triazole-substituted adenosines: a new class of selective A3 adenosine receptor agonists, partial agonists, and antagonists

scientific article published on December 2006

3'-C-branched-chain-substituted nucleosides and nucleotides as potent inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase

scientific article published in August 2003

3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase

scientific article published on April 2010

4"-O-Alkylated α-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies

scientific article published on 17 December 2018

5'-Deoxy congeners of 9-(3-amido-3-deoxy-beta-D-xylofuranosyl)-N(6)-cyclopentyladenine: new adenosine A(1) receptor antagonists and inverse agonists

scientific article published in April 2002

6'-derivatised alpha-GalCer analogues capable of inducing strong CD1d-mediated Th1-biased NKT cell responses in mice

scientific article published in December 2008

A "clickable" MTX reagent as a practical tool for profiling small-molecule-intracellular target interactions via MASPIT.

scientific article

A Dissociated Glucocorticoid Receptor Modulator Reduces Airway Hyperresponsiveness and Inflammation in a Mouse Model of Asthma

scientific article published on 05 March 2012

A bidirectional crosstalk between iNKT cells and adipocytes mediated by leptin modulates susceptibility for T cell mediated hepatitis

scientific article published on 20 August 2013

AI-2 quorum-sensing inhibitors affect the starvation response and reduce virulence in several Vibrio species, most likely by interfering with LuxPQ.

scientific article published on 24 September 2009

Acyloxybenzyl and Alkoxyalkyl Prodrugs of a Fosmidomycin Surrogate as Antimalarial and Antitubercular Agents

scientific article published on 11 September 2018

Alpha-heteroatom derivatized analogues of 3-(acetylhydroxyamino)propyl phosphonic acid (FR900098) as antimalarials

scientific article

Alternative reagents for methotrexate as immobilizing anchor moieties in the optimization of MASPIT: synthesis and biological evaluation

scientific article published on 16 February 2015

An immunogen synthesis strategy for the development of specific anti-deoxynivalenol monoclonal antibodies

scientific article published on 18 September 2014

An in silico approach for modelling T-helper polarizing iNKT cell agonists

scientific article (publication date: 2014)

Antimalarial activity of N(6)-substituted adenosine derivatives. Part 3.

scientific article published in February 2004

Antioxidant flavone glycosides from the leaves of Fargesia robusta ⬇️

scientific article published on September 2010

Autoreactivity to Sulfatide by Human Invariant NKT Cells

scientific article published on 19 May 2017

Broadening the Message: A Nanovaccine Co-loaded with Messenger RNA and α-GalCer Induces Antitumor Immunity through Conventional and Natural Killer T Cells

scientific article published on 15 February 2019

Cationic Amphiphilic Drugs Boost the Lysosomal Escape of Small Nucleic Acid Therapeutics in a Nanocarrier-Dependent Manner

scientific article published on 06 April 2020

Cinnamaldehyde and cinnamaldehyde derivatives reduce virulence in Vibrio spp. by decreasing the DNA-binding activity of the quorum sensing response regulator LuxR.

scientific article

Combining tubercidin and cordycepin scaffolds results in highly active candidates to treat late-stage sleeping sickness

scientific article published on 05 December 2019

Crystal Structures of Bovine CD1d Reveal Altered αGalCer Presentation and a Restricted A’ Pocket Unable to Bind Long-Chain Glycolipids

scientific article published in 2012

Dancing on Coke: Smuggling Cocaine Dispersed in Polyvinyl Alcohol

scientific article published on 31 October 2011

Design, synthesis and biological evaluation of novel bivalent ligands targeting Dopamine D2-like receptors and µ opioid receptor

scientific article published on 16 February 2018

Design, synthesis and biological evaluation of novel hamamelitannin analogues as potentiators for vancomycin in the treatment of biofilm related Staphylococcus aureus infections

scientific article

Determination of paramethoxyamphetamine and other amphetamine-related designer drugs by liquid chromatography/sonic spray ionization mass spectrometry

scientific article published on January 2002

Development of a liquid chromatography/tandem mass spectrometry method for the quantification of fumonisin B1, B2 and B3 in cornflakes

scientific article published in January 2005

Differential mechanism of NF-kappaB inhibition by two glucocorticoid receptor modulators in rheumatoid arthritis synovial fibroblasts

scientific article published in November 2009

Discovery of Novel 7-Aryl 7-Deazapurine 3′-Deoxy-ribofuranosyl Nucleosides with Potent Activity against Trypanosoma cruzi

Discovery of Pyrrolo[2,3-b]pyridine (1,7-Dideazapurine) Nucleoside Analogues as Anti-Trypanosoma cruzi Agents

scientific article published on 20 September 2019

Discovery of bicyclic thymidine analogues as selective and high-affinity inhibitors of Mycobacterium tuberculosis thymidine monophosphate kinase

scientific article published in December 2004

Divergent strategy for the synthesis of alpha-aryl-substituted fosmidomycin analogues

scientific article published on 12 April 2007

Double prodrugs of a fosmidomycin surrogate as antimalarial and antitubercular agents

scientific article published on 07 March 2019

Efficient Divergent Synthesis of New Immunostimulant 4″-Modified α-Galactosylceramide Analogues.

scientific article published on 5 May 2017

Elaboration of a proprietary thymidylate kinase inhibitor motif towards anti-tuberculosis agents

scientific article published on 24 August 2016

Electrospun cellulose acetate phthalate fibers for semen induced anti-HIV vaginal drug delivery

scientific article

Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism

scientific article

Exploring human adenosine A3 receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety

scientific article

Exploring the purine core of 3'-C-ethynyladenosine (EAdo) in search of novel nucleoside therapeutics

scientific article published on 03 March 2016

Fungicidal activity of truncated analogues of dihydrosphingosine

scientific article published on 20 May 2008

Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis

scientific article

Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d

scientific article

Hamamelitannin Analogues that Modulate Quorum Sensing as Potentiators of Antibiotics against Staphylococcus aureus

scientific article published on 20 April 2016

Host metabolites stimulate the bacterial proton motive force to enhance the activity of aminoglycoside antibiotics

scientific article published on 29 April 2019

Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity

scientific article published on 20 February 2009

Kinase Substrate Sensor (KISS), a mammalian in situ protein interaction sensor

scientific article

Lipid and Carbohydrate Modifications of α-Galactosylceramide Differently Influence Mouse and Human Type I Natural Killer T Cell Activation

scientific article published on 27 May 2015

Micellar Paclitaxel-Initiated RAFT Polymer Conjugates with Acid-Sensitive Behavior

Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists

scientific article published in November 2003

Modulation of adenosine receptor affinity and intrinsic efficacy in adenine nucleosides substituted at the 2-position

scientific article

Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate

scientific article

Mycobacterium tuberculosis Thymidine Monophosphate Kinase Inhibitors: Biological Evaluation and Conformational Analysis of 2′- and 3′-Modified Thymidine Analogues

scholarly article by Philippe Van Rompaey et al published August 2003 in European Journal of Organic Chemistry

New fluoroethyl phenylalanine analogues as potential LAT1-targeting PET tracers for glioblastoma

scientific article published on 27 February 2019

Novel Potentiators for Vancomycin in the Treatment of Biofilm-Related MRSA Infections via a Mix and Match Approach

scientific article

Novel hamamelitannin analogues for the treatment of biofilm related MRSA infections-A scaffold hopping approach.

scientific article published on 26 October 2016

Nucleosides with Transposed Base or 4'-Hydroxymethyl Moieties and Their Corresponding Oligonucleotides

scientific article

Optimizing the iNKT Cell Dependent Antitumor Effect Using an Altered Glycolipid

scholarly article by Sandrine Aspeslagh et al published January 2010 in Clinical Immunology

Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists

scientific article

RORγt inhibition selectively targets IL-17 producing iNKT and γδ-T cells enriched in Spondyloarthritis patients

scientific article published in Nature Communications

Rational design of 5'-thiourea-substituted alpha-thymidine analogues as thymidine monophosphate kinase inhibitors capable of inhibiting mycobacterial growth

scientific article published on 2 October 2007

Receptor-mediated targeting of cathepsins in professional antigen presenting cells

scientific article published in January 2009

Report on a novel emerging class of highly potent benzimidazole NPS opioids: Chemical and in vitro functional characterization of isotonitazene

scientific article published on 08 January 2020

Resistance of the Burkholderia cepacia complex to fosmidomycin and fosmidomycin derivatives

scientific article published on 2 July 2011

Revisiting tubercidin against kinetoplastid parasites: Aromatic substitutions at position 7 improve activity and reduce toxicity

article published in 2019

Sesquiterpene lactones from the extracts of two Balkan endemic Laserpitium species and their cytotoxic activity

scientific article

Small-molecule potentiators for conventional antibiotics against Staphylococcus aureus

scientific article published on 11 September 2017

Structural Basis for the Recognition of C20:2-αGalCer by the Invariant Natural Killer T Cell Receptor-like Antibody L363

scientific article

Structure Guided Lead Generation toward Nonchiral M. tuberculosis Thymidylate Kinase Inhibitors

scientific article published on 6 March 2018

Structure-activity relationship of cinnamaldehyde analogs as inhibitors of AI-2 based quorum sensing and their effect on virulence of Vibrio spp

scientific article

Sydnone Ribosides as a Platform for the Synthesis of Pyrazole C-Nucleosides: A Unified Synthesis of Formycin B and Pyrazofurin

scientific article published on 19 November 2020

Synthesis and In Vivo Evaluation of 4-Deoxy-4,4-difluoro-KRN7000

scientific article published in 2008

Synthesis and P2Y receptor activity of nucleoside 5'-phosphonate derivatives

scientific article published on 14 April 2009

Synthesis and P2Y₂ receptor agonist activities of uridine 5'-phosphonate analogues

scientific article published on 15 February 2012

Synthesis and antiviral evaluation of α-L-2'-deoxythreofuranosyl nucleosides

scientific article published on 20 May 2011

Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase

scientific article

Synthesis and biological evaluation of bicyclic nucleosides as inhibitors of M. tuberculosis thymidylate kinase.

scientific article published in October 2006

Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors

scientific article published in April 2006

Synthesis and biological evaluation of novel PDMP analogues

scientific article published on 18 April 2006

Synthesis and conformational analysis of 1-[2,4-dideoxy-4-C-hydroxymethyl-alpha-l-lyxopyranosyl]thymine

scientific article published in June 2004

Synthesis and evaluation of 5'-modified thymidines and 5-hydroxymethyl-2'-deoxyuridines as Mycobacterium tuberculosis thymidylate kinase inhibitors

scientific article

Synthesis and evaluation of N⁶-substituted apioadenosines as potential adenosine A₃ receptor modulators

scientific article

Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors

scientific article published on 10 June 2007

Synthesis and evaluation of alpha-halogenated analogues of 3-(acetylhydroxyamino)propylphosphonic acid (FR900098) as antimalarials

scientific article published on July 2010

Synthesis and evaluation of amino-modified alpha-GalCer analogues

scientific article published on July 2010

Synthesis and evaluation of the quorum sensing inhibitory effect of substituted triazolyldihydrofuranones.

scientific article published on 9 June 2012

Synthesis and evaluation of thiazolidinedione and dioxazaborocane analogues as inhibitors of AI-2 quorum sensing in Vibrio harveyi.

scientific article

Synthesis and in vitro evaluation of alpha-GalCer epimers

scientific article published in July 2008

Synthesis and inhibitory activity of thymidine analogues targeting Mycobacterium tuberculosis thymidine monophosphate kinase

scientific article published on 18 October 2011

Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists

scientific article published on 9 May 2008

Synthesis and structure-activity relationships of cerebroside analogues as substrates of cerebroside sulphotransferase and discovery of a competitive inhibitor

scientific article published on 01 December 2020

Synthesis of 5-substituted 2'-deoxyuridine-5'- phosphonate analogues and evaluation of their antiviral activity

scientific article published in January 2012

Synthesis of 6"-triazole-substituted α-GalCer analogues as potent iNKT cell stimulating ligands

scientific article published on 12 October 2012

Synthesis of C-5″ and C-6″-modified α-GalCer analogues as iNKT-cell agonists

scientific article

Synthesis of C6''-modified α-C-GalCer analogues as mouse and human iNKT cell agonists

scientific article

Synthesis of a 3'-C-ethynyl-β-d-ribofuranose purine nucleoside library: Discovery of C7-deazapurine analogs as potent antiproliferative nucleosides

Synthesis of a Versatile (S)-3-(Hydroxymethyl)butane-1,2,4-triol Building Block and its Application for the Stereoselective Synthesis ofN-Homoceramides

scientific article published on 01 December 2005

Synthesis of alpha-substituted fosmidomycin analogues as highly potent Plasmodium falciparum growth inhibitors

scientific article published on 24 January 2006

Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity

scientific article published on 20 May 2014

Synthesis of analogues of (E)-1-hydroxy-2-methylbut-2-enyl 4-diphosphate, an isoprenoid precursor and human gamma delta T cell activator

scientific article published on 23 January 2008

Synthesis of beta- and gamma-oxa isosteres of fosmidomycin and FR900098 as antimalarial candidates

scientific article published on 8 December 2007

Synthesis of extended uridine phosphonates derived from an allosteric P2Y2 receptor ligand

scientific article published on 4 April 2014

Synthesis of homoceramides, novel ceramide analogues, and their lack of effect on the growth of hippocampal neurons

scientific article published in February 2002

Synthesis of hypermodified adenosine derivatives as selective adenosine A3 receptor ligands

scientific article published on 2 November 2005

Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

scientific article published on 12 November 2018

Synthesis of α-Aryl-Substituted and Conformationally Restricted Fosmidomycin Analogues as Promising Antimalarials

Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors

scientific article published on 18 September 2018

Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors

scientific article published on 2 December 2010

Synthetic Fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-d-xylulose 5-phosphate Reductoisomerase or Plasmodium falciparum growth in vitro.

scientific article published on 24 February 2014

Synthetic Rhamnose Glycopolymer Cell-Surface Receptor for Endogenous Antibody Recruitment

scientific article published on 08 January 2020

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin

scientific article

The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release

scientific article published on February 2016

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

scientific article published on 11 September 2012

The influence of the acyl chain on the transdermal penetration-enhancing effect of synthetic phytoceramides.

scientific article published on 16 December 2014

The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000.

scientific article

Thymidine and thymidine-5'-O-monophosphate analogues as inhibitors of Mycobacterium tuberculosis thymidylate kinase

scientific article published in September 2003

Transiently Responsive Block Copolymer Micelles Based on N-(2-Hydroxypropyl)methacrylamide Engineered with Hydrolyzable Ethylcarbonate Side Chains

scientific article published on 9 December 2015

Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays

scientific article

Unbreakable codes in electrospun fibers: digitally encoded polymers to stop medicine counterfeiting

scientific article

Use of quorum sensing inhibitors to interfere with biofilm formation and development in Burkholderia multivorans and Burkholderia cenocepacia

scientific article published on 31 December 2008

Zwitterionic-hydrophilic interaction liquid chromatography for l-ascorbic acid 2-phosphate magnesium, a raw material in cell therapy

scientific article published on 07 December 2018

pH-Degradable Mannosylated Nanogels for Dendritic Cell Targeting

scientific article

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