List of works by Anja Wilmes

A Protocol for One-Step Differentiation of Human Induced Pluripotent Stem Cells into Mature Podocytes

scientific article published on 01 January 2019

Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: A transcriptomic study

scientific article

Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.

scientific article published on 10 December 2012

Chemical genetic profiling of the microtubule-targeting agent peloruside A in budding yeast Saccharomyces cerevisiae

article

Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq

scientific article published on 14 July 2018

Cyclosporine A kinetics in brain cell cultures and its potential of crossing the blood-brain barrier

scientific article published on 12 February 2015

Delineation of the key aspects in the regulation of epithelial monolayer formation

scientific article published on 22 April 2013

Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing.

scientific article published on December 2014

Differentiation of human iPSCs into functional podocytes

scientific article published in PLoS ONE

Effects of the microtubule stabilizing agent peloruside A on the proteome of HL-60 cells

scientific article

Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing

scientific article published on January 2016

Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel

scientific article published on 5 June 2014

Generation and characterization of iPSC-derived renal proximal tubule-like cells with extended stability

scientific article published on 02 June 2021

Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity

scientific article published on 21 December 2010

Interleukin-19 as a translational indicator of renal injury

scientific article published on 9 April 2014

Investigation of Nrf2, AhR and ATF4 Activation in Toxicogenomic Databases

scientific article published on 02 October 2018

Kinetics and dynamics of cyclosporine A in three hepatic cell culture systems.

scientific article published on 17 July 2015

Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes

scientific article published on 24 May 2011

Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics

scientific article

Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline

scientific article published on 8 June 2015

Nrf2 inducibility of aldo-keto reductases

scientific article published in June 2013

Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells

scientific article

Paclitaxel effects on the proteome of HL-60 promyelocytic leukemic cells: comparison to peloruside A.

scientific article published on 23 September 2010

Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines

scientific article published on March 2007

Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity ⬇️

scientific article

Peloruside- and laulimalide-resistant human ovarian carcinoma cells have βI-tubulin mutations and altered expression of βII- and βIII-tubulin isotypes.

scientific article

Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens

scientific article published on 03 December 2018

Renal Cell Culture

article

Structure–activity studies of the pelorusides: new congeners and semi-synthetic analogues

scientific article published on 21 April 2011

Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells

scientific article published on 17 September 2010

The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods

scientific article published on 06 July 2020

The Use of Renal Cell Culture for Nephrotoxicity Investigations

article

The bile acid deoxycholic acid (DCA) at neutral pH activates NF-kappaB and induces IL-8 expression in oesophageal cells in vitro

scientific article

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.

scientific article published on 15 August 2017

Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model

scientific article

Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing

scientific article

Translational Biomarkers, In Vitro and In Vivo

Two-Stage Model-Free Tests of Synergy in Drug Combinations

scientific article published on 01 January 2012

Use of Induced Pluripotent Stem Cells in Drug Toxicity Screening

article

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