Search filters

List of works by Emanuel Escher

A new method of iodine labelling of peptide hormones

scientific article published on 01 January 1984

A novel procedure for daily measurements of hemodynamical, hematological, and biochemical parameters in conscious unrestrained rats

scientific article published on 01 November 2000

A polyaromatic caveolin-binding-like motif in the cytoplasmic tail of the type 1 receptor for angiotensin II plays an important role in receptor trafficking and signaling

scientific article

A single-nucleotide polymorphism of alanine to threonine at position 163 of the human angiotensin II type 1 receptor impairs Losartan affinity

scientific article published in June 2010

A substance P antagonist not containing D-tryptophan.

scientific article

Activation induces structural changes in the liganded angiotensin II type 1 receptor.

scientific article published on 27 July 2009

Activation of the angiotensin II type 1 receptor leads to movement of the sixth transmembrane domain: analysis by the substituted cysteine accessibility method

scientific article published on 19 April 2007

Agonists for the Chemokine Receptor CXCR4.

scientific article published on 6 June 2011

An angiotensin II antagonist with strongly prolonged action

scientific article published on 01 May 1989

Analysis by substituted cysteine scanning mutagenesis of the fourth transmembrane domain of the CXCR4 receptor in its inactive and active state

scientific article published on 05 December 2012

Analysis of transmembrane domains 1 and 4 of the human angiotensin II AT1 receptor by cysteine-scanning mutagenesis

scientific article

Angiotensin II is bound to both receptors AT1 and AT2, parallel to the transmembrane domains and in an extended form

scientific article published on 01 May 2002

Angiotensin analogues palmitoylated in positions 1 and 4

scientific article published on 01 September 1997

Angiotensin-induced changes in the apparent size of rat liver angiotensin receptors

scientific article

Anti-angiotensin antibodies cross-reactive with nonpeptide angiotensin antagonists as angiotensin receptor model

scientific article published on 01 March 1993

Apparent molecular weight of substance P/neurokinin-1 receptors determined using a photoaffinity labelled probe, [(3'-125I) D-Tyro, (4'-N3)Phe8, Nle11]-substance P.

scientific article published in November 1987

Ascorbic acid decreases the binding affinity of the AT1 receptor for angiotensin II.

scientific article published on January 2008

Biological properties and functional determinants of the urotensin II receptor.

scientific article

Biosensing based on surface plasmon resonance and living cells

scientific article

CD36 mediates the cardiovascular action of growth hormone-releasing peptides in the heart

scientific journal article

Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity.

scientific article

Characterization of a specific binding site for angiotensin II in chicken liver

scientific article published on 01 June 1997

Characterization of spinal actions of four substance P analogues

scientific article published on 01 March 1985

Constitutive activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane 7 to the ligand-binding pocket

scientific article

Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay.

scientific article

Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs

scientific article published on 24 April 2012

Direct covalent attachment of small peptide antigens to enzyme-linked immunosorbent assay plates using radiation and carbodiimide activation

scientific article published on 01 October 1994

Effects of substance P analogues in the rat tail-flick test

scientific article published on 01 February 1987

Epitope tagging and immunoreactivity of the human angiotensin II type 1 receptor

scientific article published on 01 June 1997

Evidence for the existence of three classes of neurokinin receptors in brain. Differential ontogeny of neurokinin-1, neurokinin-2 and neurokinin-3 binding sites in rat cerebral cortex

scientific article published on 01 June 1988

Expression of the five somatostatin receptor (SSTR1-5) subtypes in rat pituitary somatotrophes: quantitative analysis by double-layer immunofluorescence confocal microscopy

scientific journal article

Functional effects of caloxin 1c2, a novel engineered selective inhibitor of plasma membrane Ca(2+)-pump isoform 4, on coronary artery.

scientific article

GPR103b functions in the peripheral regulation of adipogenesis.

scientific article

Human placental LHRH receptor: agonist and antagonist labeling produces differences in the size of the non-denatured, solubilized receptor

scientific article published in January 1988

Identification of Distinct Conformations of the Angiotensin-II Type 1 Receptor Associated with the Gq/11 Protein Pathway and the β-Arrestin Pathway Using Molecular Dynamics Simulations.

scientific article published on May 2015

Identification of angiotensin II-binding domains in the rat AT2 receptor with photolabile angiotensin analogs

scientific article published on 01 March 1997

Identification of transmembrane domain 1 & 2 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

scientific article published on 29 August 2014

Identification of transmembrane domain 3, 4 & 5 residues that contribute to the formation of the ligand-binding pocket of the urotensin-II receptor

scientific article published on 29 September 2013

Identification of transmembrane domain 6 & 7 residues that contribute to the binding pocket of the urotensin II receptor.

scientific article published on 29 January 2009

Identification of transmembrane domain residues determinant in the structure-function relationship of the human platelet-activating factor receptor by site-directed mutagenesis.

scientific article published on September 1996

Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human AT1 receptor

scientific article published on August 2005

Improved activity of a new angiotensin receptor antagonist by an injectable spray-dried polymer microsphere preparation

scientific article published on July 1, 1997

In vitro study of frog (Rana ridibunda Pallas) interrenal function by use of a simplified perifusion system

scientific article published on 01 June 1984

Influence of surface properties at biodegradable microsphere surfaces: effects on plasma protein adsorption and phagocytosis

scientific article

Inhibition of endothelin-converting enzyme for protection against neointimal proliferation following balloon angioplasty of the rat carotid artery

scientific article

Innocuity of agents for radiocontrast enhancement of urinary tract stones

scientific article published on 01 November 1995

Involvement of a cytoplasmic-tail serine cluster in urotensin II receptor internalization.

scientific article published on January 2005

Isolation and structure analysis of a photoproduct of the new photoaffinity label p-nitrophenylalanine

scientific article published on 01 March 1977

Low-energy (3-24 eV) electron damage to the peptide backbone

scientific article published on 26 January 2007

Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction

scientific article

Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding

scientific article

Monitoring of MMPs activity in vivo, non-invasively, using solubility switchable MRI contrast agent

scientific article published on 01 January 2009

Monitoring of native chemical ligation by surface plasmon resonance

scientific article published on 01 January 2009

Monitoring of native chemical ligation on solid substrate by surface plasmon resonance.

scientific article published in January 2008

Mutational analysis of the conserved Asp2.50 and ERY motif reveals signaling bias of the urotensin II receptor

scientific article

N- and C-terminal structure-activity study of angiotensin II on the angiotensin AT2 receptor

scientific article published on 01 February 1998

Neointima formation after vascular injury is angiotensin II mediated

scientific article published on 01 September 1992

New enzyme-activated solubility-switchable contrast agent for magnetic resonance imaging: from synthesis to in vivo imaging

scientific article

Novel cyclic analogs of angiotensin II with cyclization between positions 5 and 7: conformational and biological implications

scientific article published on 01 July 1996

Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity in vivo in a mouse model

scientific article

Partial agonists and antagonists for substance P.

scientific article published in July 1983

Partial agonists and antagonists for substance P.

scientific article

Photoaffinity cross-linking of the corticotropin-releasing factor receptor type 1 with photoreactive urocortin analogues.

scientific article published on November 2005

Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptor-bound angiotensin II adopts an extended structure

scientific article published on 01 August 2000

Photolabelling the rat urotensin II/GPR14 receptor identifies a ligand-binding site in the fourth transmembrane domain.

scientific article published on March 2003

Photolabelling the urotensin II receptor reveals distinct agonist- and partial-agonist-binding sites

scientific article published on February 2007

Preliminary biochemical characterization of the novel, non-AT1, non-AT2 angiotensin binding site from the rat brain

scientific article published on April 13, 2010

Receptors for substance P. I. The pharmacological preparations

scientific article published in January 1984

Receptors for substance P. II. Classification by agonist fragments and homologues

scientific article published on 01 January 1984

Receptors for substance P. III. Classification by competitive antagonists

scientific article published on 01 January 1984

Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor.

scientific article

Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptor

scientific article published on 13 December 2005

Role of calcium in stimulus-secretion coupling on isolated frog interrenal gland

scientific article published on 01 March 1986

S-nitrosylation of cysteine 289 of the AT1 receptor decreases its binding affinity for angiotensin II

scientific article published on June 2006

Sar1-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor

scientific article published on 01 March 1993

Specific and irreversible block of the myotropic action of angiotensin II

scientific article published on September 14, 1978

Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: improved incorporation and absence of methionine selectivity

scientific article published on 01 April 2006

Structure-Activity Relationship and Signaling of New Chimeric CXCR4 Agonists

scientific article published on 19 July 2016

Substance P antagonists active in vitro and in vivo.

scientific article

Substance P antagonists showing some selectivity for different receptor types

scientific article published in February 1985

Substance P--structure-activity studies and the development of antagonists.

scientific article

Synthesis of an agonistic, difluoro-azido photolabel of angiotensin II and labeling of the AT1 receptor: transmembrane domains 3, 6, and 7 form the ligand-binding pocket

scientific article published in January 2006

Tachykinin antagonists: substitutions in positions 5 and 6 with amino acids from the primary sequence of substance P homologues

scientific article published in August 1985

Tachykinin receptors in smooth muscles: a study with agonists (substance P, neurokinin A) and antagonists.

scientific article published on November 1985

Temperature dependent photolabeling of the human angiotensin II type 1 receptor reveals insights into its conformational landscape and its activation mechanism

scientific article published on 19 June 2010

Temperature-dependent variations of ligand-receptor contact points in hAT(1)

scientific article published on 01 September 2007

The active and the inactive form of the hAT1 receptor have an identical ligand-binding environment: an MPA study on a constitutively active angiotensin II receptor mutant

scientific article published in January 2006

The amino-terminus of angiotensin II contacts several ectodomains of the angiotensin II receptor AT1.

scientific article published in March 2010

The angiotensin II binding site on Mycoplasma hyorhynis is structurally distinct from mammalian AT1 and AT2 receptors

scientific article published on 01 January 1998

The constitutively active N111G-AT1 receptor for angiotensin II maintains a high affinity conformation despite being uncoupled from its cognate G protein Gq/11alpha

scientific article published on 13 August 2003

The constitutively active N111G-AT1 receptor for angiotensin II modifies the morphology and cytoskeletal organization of HEK-293 cells.

scientific article

The fifth transmembrane domain of angiotensin II Type 1 receptor participates in the formation of the ligand-binding pocket and undergoes a counterclockwise rotation upon receptor activation

scientific article published on 22 September 2009

The hydra head activator in human blood circulation. Degradation of the synthetic peptide by plasma angiotensin-converting enzyme

scientific article published on 01 August 1984

The neurogenic origin of hypertension in SHR may be mediated by angiotensin II through a receptor different from AT1 and AT2

scientific article published on 01 August 1993

The second transmembrane domain of the human type 1 angiotensin II receptor participates in the formation of the ligand binding pocket and undergoes integral pivoting movement during the process of receptor activation

scientific article

Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea

scientific article published in March 1984

Use of LiCl in phospholipase C assays masks the impaired functionality of a mutant angiotensin II receptor

scientific article published on 01 August 1997

Visualization of neurokinin-3 receptor sites in rat brain using the highly selective ligand [3H]senktide

scientific article published on 01 January 1990

What can angiotensin antagonists do that converting-enzyme inhibition can't: the case of post-angioplastic restenosis

scientific article published on 01 July 1996

[Photoaffinity labelling of chymotrypsin. Synthesis of photorecognizable ligands]

scientific article published on 01 July 1975

[The methionine proximity assay: an approach to glean receptor structures]

scientific article published on 01 December 2006

[The synthesis of 4'-azido-3',5'-ditritio-l-phenylalanine peptides as "photo-affinity probes" for ligand-receptor interaction (author's transl)]

scientific article published on 01 April 1976

beta 2-Inhibin contains the active core of human seminal plasma beta-inhibin: synthesis and bioactivity

scientific article published in February 1985