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List of works by James Dalton

Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer.

scientific article

An allosteric modulator to control endogenous G protein-coupled receptors with light.

scientific article published on 31 August 2014

An evaluation of automated homology modelling methods at low target template sequence similarity

scientific article published on 17 May 2007

Analysis of positive and negative allosteric modulation in metabotropic glutamate receptors 4 and 5 with a dual ligand.

scientific article published on 10 July 2017

Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia

scientific article

Artificial Intelligence: A Novel Approach for Drug Discovery

scientific article published on 3 July 2019

Calculation of helix packing angles in protein structures

scientific article published in July 2003

Computational analysis of negative and positive allosteric modulator binding and function in metabotropic glutamate receptor 5 (in)activation

scientific article published on 13 May 2014

Correction: Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex

scholarly article in RSC Advances, vol. 8 no. 30, 2018

Exploring the Activation Mechanism of the mGlu5 Transmembrane Domain

scientific article published on 06 March 2020

GNAO1 encephalopathy: further delineation of a severe neurodevelopmental syndrome affecting females.

scientific article

Helix 3 acts as a conformational hinge in Class A GPCR activation: An analysis of interhelical interaction energies in crystal structures

scientific article published on 29 October 2015

Homology-modelling protein-ligand interactions: allowing for ligand-induced conformational change

scientific article published on 29 April 2010

Illuminating Phenylazopyridines To Photoswitch Metabotropic Glutamate Receptors: From the Flask to the Animals

scientific article published on 19 December 2016

Insights into adenosine A2A receptor activation through cooperative modulation of agonist and allosteric lipid interactions

scientific article published on 16 April 2020

New model of cystic fibrosis transmembrane conductance regulator proposes active channel-like conformation.

scientific article published on 12 July 2012

Positional isomers of bispyridine benzene derivatives induce efficacy changes on mGlu5 negative allosteric modulation.

scientific article published on 12 January 2017

Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.

scientific article published on 23 April 2015

Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex

scholarly article in RSC Advances, vol. 5 no. 33, 2015

Revealing the Mechanism of Agonist-Mediated Cannabinoid Receptor 1 (CB1) Activation and Phospholipid-Mediated Allosteric Modulation

scientific article published on 29 May 2019

Selective Protonation of Acidic Residues Triggers Opsin Activation

scientific article published on 17 July 2015

Shining Light on an mGlu5 Photoswitchable NAM: A Theoretical Perspective

scientific article published on 7 April 2015

Statistics for the analysis of molecular dynamics simulations: providing P values for agonist-dependent GPCR activation

scientific article published on 17 November 2020

Structural insights into positive and negative allosteric regulation of a G protein-coupled receptor through protein-lipid interactions.

scientific article

Synthesis toward Bivalent Ligands for the Dopamine D2 and Metabotropic Glutamate 5 Receptors

scientific article published on 18 September 2018

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