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List of works by Per I Arvidsson

3-Oxoisoindoline-1-carboxamides: potent, state-dependent blockers of voltage-gated sodium channel Na(V)1.7 with efficacy in rat pain models

scientific article

5-(Pyrrolidine-2-yl)tetrazole: Rationale for the Increased Reactivity of the Tetrazole Analogue of Proline in Organocatalyzed Aldol Reactions

5-(Pyrrolidine-2-yl)tetrazole: Rationale for the Increased Reactivity of the Tetrazole Analogue of Proline in Organocatalyzed Aldol Reactions

6Li and 15N NMR Data as a Probe for the Influence of Solvent and Intramolecular Solvation on the Solution-State Structures of Chiral Lithium Amides

scientific article published on 01 April 2000

A Facile Synthesis of NODASA-Functionalized Peptide

A Synthesis of "Dual Warhead" β-Aryl Ethenesulfonyl Fluorides and One-Pot Reaction to β-Sultams.

scientific article

AZD1080, a novel GSK3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

scientific article published on 11 March 2013

Alzheimer's disease: presenilin 2-sparing γ-secretase inhibition is a tolerable Aβ peptide-lowering strategy

scientific article published in November 2012

An Efficient Protecting-Group-Free Synthesis of Vinylic Sulfoximines via Horner–Wadsworth–Emmons Reaction

An improved synthesis of Fmoc-N-methyl-alpha-amino acids

scientific article published in August 2005

An unexpected re-arrangement of the antibiotic carbapenem core to new 1,4-diazepin-5-one scaffolds

scholarly article in RSC Advances, vol. 8 no. 1, 2018

Antibiotic and Hemolytic Activity of a β2/β3 Peptide Capable of Folding into a 12/10-Helical Secondary Structure

scientific article published on 01 December 2003

Application of novel sulfonamides in enantioselective organocatalyzed cyclopropanation

Applied Enantioselective Aminocatalysis: α-Heteroatom Functionalization Reactions on the Carbapenem (β-Lactam Antibiotic) Core

Asymmetric conjugate addition of thioglycolate to a range of chalcones using tetrahydroisoquinoline (TIQ) N,N′-dioxide ligands

article

Beta2-amino acids in the design of conformationally homogeneous cyclo-peptide scaffolds

scientific article

Biomolecular recognition of glycosylated β3-peptides by GalNAc specific lectins

scholarly article by Anna S. Norgren published in January 2007

Chiral Lithium Amide/Solute Complexes: X-ray Crystallographic and NMR Spectroscopic Studies

Cinchona alkaloid derived ligands in catalytic asymmetric transfer hydrogenation

scientific article published in July 2003

Clofazimine protects against mycobacterium tuberculosis dissemination in the CNS following an aerosol challenge in a murine model.

scientific article

Cobalt-dopedβ-peptide nanotubes: A class of spintronic materials

scholarly article in Physical Review B, vol. 77 no. 15, April 2008

Combining an amyloid-beta (Aβ) cleaving enzyme inhibitor with a γ-secretase modulator results in an additive reduction of Aβ production

scientific article published on 7 November 2014

Computational Study of the Mechanism of Isomerization of Allyl Alcohol into Homoallyl Alcohol by Lithium Amide

Computational, ReactIR-, and NMR-spectroscopic investigations on the chiral formyl anion equivalent N-(alpha-lithiomethylthiomethyl)-4-isopropyl-5,5-diphenyloxazolidin-2-one and related compounds

scientific article published in October 2001

Cu(OAc)2 promoted Chan–Evans–Lam C–N cross coupling reactions on the N- and N′-nitrogen atoms of sulfonimidamides with aryl boronic acids

Cu(OAc)2-Catalysed Oxidative Dual C-H/N-H Activation of Terminal Alkynes andN-Deprotected Sulfonimidamides: An Easy Access toN-Alkynylated Sulfonimidamides

article by Ganesh Chandra Nandi et al published 17 March 2015 in European Journal of Organic Chemistry

Cyclic beta-tetra- and pentapeptides: synthesis through on-resin cyclization and conformational studies by X-ray, NMR and CD spectroscopy and theoretical calculations

scientific article published in October 2005

Design and study of peptide-based inhibitors of amylin cytotoxicity

scientific article published on 11 January 2010

Design and synthesis of glycosylated beta3-peptides capable of folding into the 3(14)-helical conformation in water

scientific article

Design, machine synthesis, and NMR-solution structure of a β-heptapeptide forming a salt-bridge stabilised 314-helix in methanol and in water

article published in 2001

Effects of Congo red on aβ(1-40) fibril formation process and morphology

scientific article published on 3 February 2010

Enantioselective Organocatalyzed Transformations of β-Ketoesters.

scientific article

Enantioselective butylation of aliphatic aldehydes by mixed chiral lithium amide/n-BuLi dimers

Exploring the antibacterial and hemolytic activity of shorter- and longer-chain beta-, alpha,beta-, and gamma-peptides, and of beta-peptides from beta2-3-aza- and beta3-2-methylidene-amino acids bearing proteinogenic side chains--a survey.

scientific article published in March 2005

Facile Synthesis of N-protected Amino Acid Esters Assisted by Microwave Irradiation

Facile synthesis of Fmoc-N-methylated α- and β-amino acids

Functionalized foldamers: synthesis and characterization of a glycosylated β-peptide 314-helix conveying the TN-antigen

scientific article published on 16 March 2005

Glycosylated foldamers: synthesis of carbohydrate-modified beta3hSer and incorporation into beta-peptides

scientific article published in November 2007

Imidazopyridine-Based Inhibitors of Glycogen Synthase Kinase 3: Synthesis and Evaluation of Amide Isostere Replacements of the Carboxamide Scaffold

scientific article published on 01 November 2012

In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Abeta aggregation

scientific article published on July 2010

Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab.

scientific article published on 7 April 2017

Interaction of beta-amyloid interactions with peptide functionalized gold nanoparticles.

scientific article

Intraaggregate Fluxional Lithium and Carbanion Exchanges in a Chiral Lithium Amide/n-Butyllithium Mixed Tetramer Directly Observed by Multinuclear NMR

Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent.

scientific article

Mechanistic insights into the phosphine-free RuCp*-diamine-catalyzed hydrogenation of aryl ketones: experimental and theoretical evidence for an alcohol-mediated dihydrogen activation

scientific article

Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells

scientific article

Microwave-Assisted Synthesis of Guanidine Organocatalysts Bearing a Tetrahydroisoquinoline Framework and Their Evaluation in Michael Addition Reactions

article

N-Trifluoromethylthiolated Sulfonimidamides and Sulfoximines: Anti-microbial, Anti-mycobacterial, and Cytotoxic Activity

scientific article published on 11 September 2019

NOTA: a potent metallo-β-lactamase inhibitor.

scientific article published on 6 January 2015

Neuroprotective potential of Linezolid: a quantitative and distribution study via mass spectrometry.

scientific article published on 21 June 2016

Novel Bioactivation Mechanism of Reactive Metabolite Formation from Phenyl Methyl-Isoxazoles

scientific article published on 20 August 2012

Novel tetrahydroisoquinoline based organocatalysts for asymmetric Diels–Alder reactions: insight into the catalytic mode using ROESY NMR and DFT studies

On the antimicrobial and hemolytic activities of amphiphilic beta-peptides

scientific article published on 01 October 2001

On the bridge over the translational valley of death: interview with Per I Arvidsson.

scientific article

On-Water Synthesis of Biaryl Sulfonyl Fluorides

scientific article published on 29 February 2016

Open for collaboration: an academic platform for drug discovery and development at SciLifeLab

scientific article

Organocatalytic Mannich Reactions on a Carbapenem Core - Synthesis of Mannich Bases and Bicyclic Diazanonanes

Organocatalytic asymmetric cross-aldol reaction of 2-chloroethoxy acetaldehyde: diversity-oriented synthesis of chiral substituted 1,4-dioxanes and morpholines

Organocatalytic synthesis of chiral benzopyrans

Organocatalyzed Mannich reactions on minocycline: Towards novel tetracycline antibiotics

Organocatalyzed stereospecific C-C bond formation of β-lactams

scientific article published on 11 November 2013

Pd-catalyzed C–N coupling of vinylbromides and sulfonimidamides: a facile synthesis of N′-vinylsulfonimidamides

scholarly article in RSC Advances, vol. 5 no. 76, 2015

Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease

scientific article published on March 2011

Pentacycloundecane-diol-based HIV-1 protease inhibitors: biological screening, 2D NMR, and molecular simulation studies

scientific article published on 27 April 2012

Phenyl isoxazole voltage-gated sodium channel blockers: Structure and activity relationship

scientific article published on 18 May 2011

Poly-N-methylated amyloid beta-peptide (Abeta) C-terminal fragments reduce Abeta toxicity in vitro and in Drosophila melanogaster

scientific article published in December 2009

Poly-N-methylated α-peptides: synthesis and X-ray structure determination of β-strand forming foldamers

scientific article published on 20 December 2005

Preclinical Characterization of Acyl Sulfonimidamides: Potential Carboxylic Acid Bioisosteres with Tunable Properties

scientific article published on 28 January 2015

Proline N-oxides: modulators of the 3D conformation of linear peptides through "NO-turns".

scientific article

Rational Design of Chiral Lithium Amides for Asymmetric Alkylation Reactions-NMR Spectroscopic Studies of Mixed Lithium Amide/Alkyllithium Complexes

Rational design of asymmetric organocatalysts––increased reactivity and solvent scope with a tetrazolic acid

article by Antti Hartikka & Per I Arvidsson published June 2004 in Tetrahedron: Asymmetry

Solution Structure of a Dilithiumamide/Diethylzinc Heterocomplex that Catalyzes Asymmetric Alkylation Reactions

Solvent induced isomerization of 2-cyclohexen-1-ol to 3-cyclohexen-1-ol by a chiral lithium amide

Solvent-induced stereospecific isomerization of an allylic alcohol to a homoallylic alcohol catalyzed by a chiral lithium amide

Stereoselective Diamine Chelates of a Chiral Lithium Amide Dimer: New Insights into the Coordination Chemistry of Chiral Lithium Amides

scientific article published in 1999

Stereoselective solvent induced 1,3-proton transfer of an allylic alkoxide to a homoallylic alkoxide catalysed by a chiral lithium amideElectronic supplementary information (ESI) available: 1H NMR, 1H,1H-COSY NMR and 1H,1H-NOESY NMR spectra of 6; 1H

Sulfonimidamide in medizinischer Chemie und Agrochemie

Sulfonimidamides as sulfonamides bioisosteres: rational evaluation through synthetic, in vitro, and in vivo studies with γ-secretase inhibitors

scientific article published on 3 February 2012

Sulfonimidamides in Medicinal and Agricultural Chemistry

scientific article published on 13 December 2016

Sulfonyl Fluorides (SFs): More Than Click Reagents?

Synthesis and Circular Dichroism Spectroscopic Investigations of Oligomeric β-Peptoids with α-Chiral Side Chains

scientific article published on 01 September 2006

Synthesis and NMR elucidation of novel pentacycloundecane-based peptides

scientific article published in June 2010

Synthesis and application of novel imidazole and 1H-tetrazolic acid containing catalysts in enantioselective organocatalyzed Diels–Alder reactions

Synthesis and arylation of unprotected sulfonimidamides

Synthesis and structural studies of pentacycloundecane-based HIV-1 PR inhibitors: a hybrid 2D NMR and docking/QM/MM/MD approach

scientific article published on 7 June 2011

Synthesis of Vinyl- and Aryl-Acyl Sulfonimidamides Through Pd-Catalyzed Carbonylation Using Mo(CO)6as ex situ CO Source

Synthesis of novel 1,2,4-thiadiazinane 1,1-dioxides via three component SuFEx type reaction

scholarly article in RSC Advances, vol. 8 no. 65, 2018

Synthesis of novel aryl and heteroaryl acyl sulfonimidamides via Pd-catalyzed carbonylation using a nongaseous precursor

scientific article

Synthesis, 2D-NMR and molecular modelling studies of pentacycloundecane lactam-peptides and peptoids as potential HIV-1 wild type C-SA protease inhibitors

scientific article

Synthesis, screening and computational investigation of pentacycloundecane-peptoids as potent CSA-HIV PR inhibitors

article

Synthetic approaches to radiochemical probes for imaging of bacterial infections.

scientific article published on 29 March 2017

Tetrahydroisoquinoline-Based N-Oxides as Chiral Organocatalysts for the Asymmetric Allylation of Aldehydes

Tetrazolic Acid Functionalized Dihydroindol: Rational Design of a Highly Selective Cyclopropanation Organocatalyst

scientific article published on 22 June 2007

The Outstanding Biological Stability ofβ- andγ-Peptides toward Proteolytic Enzymes: An In Vitro Investigation with Fifteen Peptidases

scientific article published in 2001

The Structure of a Chiral Lithium Amidocuprate in Solution Determined by Multinuclear NMR Spectroscopy

scientific article published in 2000

The downfall of TBA-354 - a possible explanation for its neurotoxicity via mass spectrometric imaging.

scientific article published in September 2017

The effect of N-methylation of amino acids (Ac-X-OMe) on solubility and conformation: a DFT study.

scientific article published on 20 August 2015

The outstanding biological stability of beta- and gamma-peptides toward proteolytic enzymes: an in vitro investigation with fifteen peptidases

scientific article published on 01 June 2001

The outstanding metabolic stability of a 14C-labeled beta-nonapeptide in rats--in vitro and in vivo pharmacokinetic studies

scientific article published in September 2002

Toward Solution-State Structure. A6Li,1H HOESY NMR, X-ray Diffraction, Semiempirical (PM3, MNDO), and ab Initio Computational Study of a Chiral Lithium Amide

article published in 1998

Towards a stereoselective synthesis of α,α-disubstituted proline analogues

Triazolopyrimidinones as γ-secretase modulators: structure–activity relationship, modulator profile, and in vivo profiling

article

l-Proline organocatalyzed Michael synthesis of monobactam and carbapenem β-lactam cores

β- and γ-Di- and Tripeptides as Potential Substrates for the Oligopeptide Transporter hPepT1

scientific article published on 21 September 2007

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