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List of works by Thomas Jespersen

5-HT1A receptors modulate small-conductance Ca2+-activated K+ channels

scientific article published in December 2004

A Novel SCN5A Mutation in a Patient with Coexistence of Brugada Syndrome Traits and Ischaemic Heart Disease

scientific article published on 13 October 2009

A Novel SCN5A Variant Associated with Abnormal Repolarization, Atrial Fibrillation, and Reversible Cardiomyopathy.

scientific article published on 10 April 2018

A novel nonsense variant in Nav1.5 cofactor MOG1 eliminates its sodium current increasing effect and may increase the risk of arrhythmias

scientific article

A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein

scientific article

AMP-activated protein kinase downregulates Kv7.1 cell surface expression

scientific article

Activation of big conductance Ca(2+)-activated K (+) channels (BK) protects the heart against ischemia-reperfusion injury

scientific article

Amiodarone Treatment in the Early Phase of Acute Myocardial Infarction Protects Against Ventricular Fibrillation in a Porcine Model

scientific article published on 07 January 2019

An ERG channel inhibitor from the scorpion Buthus eupeus

scientific article

An RNA secondary structure bias for non-homologous reverse transcriptase-mediated deletions in vivo

scientific article published on 6 April 2004

Analyses of a novel SCN5A mutation (C1850S): conduction vs. repolarization disorder hypotheses in the Brugada syndrome

scientific article published on 5 February 2008

Antiarrhythmic Effect of Either Negative Modulation or Blockade of Small Conductance Ca2+-activated K+ Channels on Ventricular Fibrillation in Guinea Pig Langendorff-perfused Heart

scientific article published on 01 September 2015

Antiarrhythmic Effects of Combining Dofetilide and Ranolazine in a Model of Acutely Induced Atrial Fibrillation in Horses.

scientific article published on 25 October 2017

Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium

scientific article

Antiarrhythmic and electrophysiologic effects of flecainide on acutely induced atrial fibrillation in healthy horses.

scientific article published on 18 October 2014

Antiarrhythmic effect of IKr activation in a cellular model of LQT3.

scientific article published on 17 October 2008

Antiarrhythmic effect of the Ca2+-activated K+ (SK) channel inhibitor ICA combined with either amiodarone or dofetilide in an isolated heart model of atrial fibrillation.

scientific article published on 8 October 2016

Arrhythmia development during inhibition of small-conductance calcium-activated potassium channels in acute myocardial infarction in a porcine model

scientific article published on 01 October 2019

Associations between thyroid-stimulating hormone, blood pressure and adiponectin are attenuated in children and adolescents with overweight or obesity

scientific article published on 01 December 2019

Attenuated Ventricular β-Adrenergic Response and Reduced Repolarization Reserve in a Rabbit Model of Chronic Heart Failure

article

Basolateral localisation of KCNQ1 potassium channels in MDCK cells: molecular identification of an N-terminal targeting motif

scientific article

Biophysical characterization of KV3.1 potassium channel activating compounds.

scientific article

Biophysical characterization of inwardly rectifying potassium currents (I(K1) I(K,ACh), I(K,Ca)) using sinus rhythm or atrial fibrillation action potential waveforms

scientific article published on 01 October 2015

Brugada Syndrome Unmasked by Accidental Inhalation of Gasoline Vapors

scientific article published on 01 October 2007

Cardiac channelopathies and sudden infant death syndrome

scientific article published on 16 July 2011

Cardiac sodium channel Na(v)1.5 interacts with and is regulated by the protein tyrosine phosphatase PTPH1

scientific article

Cardiovascular changes in childhood obesity ⬇️

scientific article published in November 2017

Characterization of cardiac repolarization in the Göttingen minipig

scientific article

Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current

scientific article published on 27 May 2008

Characterization of two new dominant ClC-1 channel mutations associated with myotonia

scientific article published in December 2003

Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family.

scientific article

Common and Rare Variants in SCN10A Modulate the Risk of Atrial Fibrillation

article published in 2015

Common and rare variants in SCN10A modulate the risk of atrial fibrillation

scientific article

Comparison of hemodynamics, cardiac electrophysiology, and ventricular arrhythmia in an open- and a closed-chest porcine model of acute myocardial infarction

scientific article published on 10 January 2020

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

scientific article

Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels

scientific article

Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

scientific article published on 14 July 2015

Difference in allelic expression of the CLCN1 gene and the possible influence on the myotonia congenita phenotype

scientific article published in September 2004

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

scientific article

Does KCNE5 play a role in long QT syndrome?

scientific article

Double mutation at the putative protein kinase C phosphorylation sites Thr151 plus Thr323 in the mouse leukotrieneD4 receptor eliminates homologous desensitization

scientific article published on 6 March 2013

Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes.

scientific article

Effect of flecainide on atrial fibrillatory rate in a large animal model with induced atrial fibrillation.

scientific article published on 8 December 2017

Effect of induced chronic atrial fibrillation on exercise performance in Standardbred trotters

Effect of the I(to) activator NS5806 on cloned K(V)4 channels depends on the accessory protein KChIP2.

scientific article

Effects of dofetilide and ranolazine on atrial fibrillatory rate in a horse model of acutely induced atrial fibrillation

scientific article published on 28 January 2019

Effects on Atrial Fibrillation in Aged Hypertensive Rats by Ca 2+ -Activated K + Channel Inhibition

Efficient Non-PCR-Mediated Overlap Extension of PCR Fragments by Exonuclease “End Polishing” ⬇️

scientific article published on July 1, 1997

Electrophysiologic effects of the IK1 inhibitor PA-6 are modulated by extracellular potassium in isolated guinea pig hearts

scientific article published on 13 January 2017

Expression of heterologous genes from an IRES translational cassette in replication competent murine leukemia virus vectors.

scientific article published on November 1999

Flecainide Provocation Reveals Concealed Brugada Syndrome in a Long QT Syndrome Family With a Novel L1786Q Mutation in SCN5A

article

Functional testing of a bicistronic retroviral vector for intracellular peptide production

scientific article published on June 1999

Functionally selective AT(1) receptor activation reduces ischemia reperfusion injury.

scientific article

G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization

scientific article published on 22 October 2013

GIRK channel activation via adenosine or muscarinic receptors has similar effects on rat atrial electrophysiology.

scientific article published in August 2013

High prevalence of long QT syndrome-associated SCN5A variants in patients with early-onset lone atrial fibrillation

scientific article published on 8 June 2012

Identification of a Kir3.4 mutation in congenital long QT syndrome

scientific journal article

Impact of arrhythmogenic calmodulin variants on small conductance Ca2+ -activated K+ (SK3) channels

scientific article published on 01 October 2019

Inherited cardiac diseases caused by mutations in the Nav1.5 sodium channel

scientific article published on 20 October 2009

Inhibition of Small Conductance Calcium-Activated Potassium (SK) Channels Prevents Arrhythmias in Rat Atria During β-Adrenergic and Muscarinic Receptor Activation.

scientific article

Inhibition of small-conductance Ca2+-activated K+ channels terminates and protects against atrial fibrillation

scientific article published on 19 June 2010

Investigations of the Navβ1b sodium channel subunit in human ventricle; functional characterization of the H162P Brugada syndrome mutant.

scientific article published on 21 February 2014

KCNQ1 channels sense small changes in cell volume

scientific article published on 17 April 2003

KCNQ4 channel activation by BMS-204352 and retigabine

scientific article

Keeping the rhythm -- pro-arrhythmic investigations in isolated Göttingen minipig hearts

scientific article published on 17 May 2011

Kv3.1/Kv3.2 channel positive modulators enable faster activating kinetics and increase firing frequency in fast-spiking GABAergic interneurons

scientific article

Late Sodium Current in Human Atrial Cardiomyocytes from Patients in Sinus Rhythm and Atrial Fibrillation

scientific article

Longitudinal study of electrical, functional and structural remodelling in an equine model of atrial fibrillation

scientific article published on 21 October 2019

Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins

scientific article

Mutational library analysis of selected amino acids in the receptor binding domain of envelope of Akv murine leukemia virus by conditionally replication competent bicistronic vectors

scientific article published in October 2003

Mutations in sodium channel β-subunit SCN3B are associated with early-onset lone atrial fibrillation

scientific article

Next-generation sequencing of AV nodal reentrant tachycardia patients identifies broad spectrum of variants in ion channel genes

scientific article

PKC and AMPK regulation of Kv1.5 potassium channels

scientific article

Patients With Long-QT Syndrome Caused by Impaired hERG-Encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated With Reactive Hypoglycemia

scientific article

Pharmacologic inhibition of small-conductance calcium-activated potassium (SK) channels by NS8593 reveals atrial antiarrhythmic potential in horses.

scientific article published on 24 December 2014

Pharmacological blockade of small conductance Ca2+-activated K+ channels by ICA reduces arrhythmic load in rats with acute myocardial infarction

scientific article published on 11 March 2017

Pharmacological exploration of the resting membrane potential reserve: Impact on atrial fibrillation

scientific article

Pharmacological inhibition of IK1 by PA-6 in isolated rat hearts affects ventricular repolarization and refractoriness

scientific article

Pharmacological modulation of SK3 channels.

scientific article published in June 2001

Pharmacological rescue of mutated Kv3.1 ion-channel linked to progressive myoclonus epilepsies

scientific article published on 09 June 2018

Pharmacologically induced long QT type 2 can be rescued by activation of IKs with benzodiazepine R-L3 in isolated guinea pig cardiomyocytes

scholarly article by Jakob Dahl Nissen et al published August 2009 in Journal of Cardiovascular Pharmacology

Rat Models of Ventricular Fibrillation Following Acute Myocardial Infarction

scientific article published on January 2017

Refractoriness in human atria: Time and voltage dependence of sodium channel availability.

scientific article

Regulation and physiological function of Nav1.5 and KCNQ1 channels ⬇️

scientific article published on May 1, 2011

Regulation of Kv1.4 potassium channels by PKC and AMPK kinases

scientific article published on 23 November 2017

Screening of KCNN3 in patients with early-onset lone atrial fibrillation

Sick Sinus Syndrome, Progressive Cardiac Conduction Disease, Atrial Flutter and Ventricular Tachycardia Caused by a Novel SCN5A Mutation

article published in 2010

Small-conductance calcium-activated potassium (SK) channels contribute to action potential repolarization in human atria

scientific article published on 9 May 2014

Solid-phase synthesis and biological activity of a thioether analogue of conotoxin G1.

scientific article

Stability of Circulating Blood-Based MicroRNAs - Pre-Analytic Methodological Considerations

scientific article

Subtype-specific, bi-component inhibition of SK channels by low internal pH.

scientific article published on 20 March 2006

Synergistic antiarrhythmic effect of combining inhibition of Ca²⁺-activated K⁺ (SK) channels and voltage-gated Na⁺ channels in an isolated heart model of atrial fibrillation.

scientific article

Termination of Vernakalant-Resistant Atrial Fibrillation by Inhibition of Small-Conductance Ca2+-Activated K+ Channels in Pigs

scientific article published on October 2017

The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity, and Cardiac Function in Zebrafish

scientific article

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

scientific article

The KCNQ1 potassium channel: from gene to physiological function

scientific article

The KCNQ5 potassium channel from mouse: a broadly expressed M-current like potassium channel modulated by zinc, pH, and volume changes

scientific journal article

The KCa2 Channel Inhibitor AP14145, But Not Dofetilide or Ondansetron, Provides Functional Atrial Selectivity in Guinea Pig Hearts

scientific article published on 19 June 2019

The Prevalence of Mutations inKCNQ1, KCNH2,andSCN5Ain an Unselected National Cohort of Young Sudden Unexplained Death Cases

article by BO GREGERS WINKEL et al published 6 August 2012 in Journal of Cardiovascular Electrophysiology

The corticosteroid hormone induced factor: a new modulator of KCNQ1 channels?

scientific article published on 24 January 2006

The role of CAV3 in long-QT syndrome: clinical and functional assessment of a caveolin-3/Kv11.1 double heterozygote versus caveolin-3 single heterozygote

scientific article

The role of the sodium current complex in a nonreferred nationwide cohort of sudden infant death syndrome

The sodium channel activator Lu AE98134 normalizes the altered firing properties of fast spiking interneurons in Dlx5/6+/- mice

scientific article published on 5 October 2017

Time-dependent antiarrhythmic effects of flecainide on induced atrial fibrillation in horses

scientific article published on 22 August 2018

Transgene stability for three replication-competent murine leukemia virus vectors

scientific article published on March 2004

Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.

scientific article

Two missense mutations in KCNQ1 cause pituitary hormone deficiency and maternally inherited gingival fibromatosis.

scientific article published on 3 November 2017

Utility of left atrial strain for predicting atrial fibrillation following ischemic stroke

scientific article published on 26 April 2019

Ventricular tachycardia in a Brugada syndrome patient caused by a novel deletion in SCN5A

scientific article published in March 2009

[Inherited cardiac diseases caused by Nav1.5 sodium channel mutations]

scientific article published on 01 April 2009

hKCNE4 inhibits the hKCNQ1 potassium current without affecting the activation kinetics

scientific article

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