Search filters

List of works by Shree Ram Singh

A patient-derived orthotopic xenograft (PDOX) nude-mouse model precisely identifies effective and ineffective therapies for recurrent leiomyosarcoma

scientific article published on 23 February 2019

A pharmacogenomic analysis using L1000CDS2 identifies BX-795 as a potential anticancer drug for primary pancreatic ductal adenocarcinoma cells

scientific article published on 09 August 2019

Assortative mating in Drosophila adapted to a microsite ecological gradient

scientific article published in November 2005

Cancer Stem Cells and Stem Cell Tumors in Drosophila

scientific article published on 01 January 2019

Cancer metabolism: targeting metabolic pathways in cancer therapy.

scientific article published on 21 June 2014

Cancer stem cells: Recent developments and future prospects ⬇️

scientific article published on April 10, 2013

Cartilage Regeneration of Adipose-Derived Stem Cells in the TGF-β1-Immobilized PLGA-Gelatin Scaffold

scientific article published in June 2015

Circulating Endothelial Progenitor Cells in Crohn's Disease: An EPiC in the Making?

scientific article published on 01 March 2017

Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model

scientific article published on 01 September 2019

Combination of Trabectedin With Irinotecan, Leucovorin and 5-Fluorouracil Arrests Primary Colorectal Cancer in an Imageable Patient-derived Orthotopic Xenograft Mouse Model

scientific article published on 01 December 2019

Combination of Trabectedin With Oxaliplatinum and 5-Fluorouracil Arrests a Primary Colorectal Cancer in a Patient-derived Orthotopic Xenograft Mouse Model

scientific article published on 01 November 2019

Combining Tumor-Selective Bacterial Therapy with Salmonella typhimurium A1-R and Cancer Metabolism Targeting with Oral Recombinant Methioninase Regressed an Ewing's Sarcoma in a Patient-Derived Orthotopic Xenograft Model

scientific article published on 01 January 2018

Competitiveness for the niche and mutual dependence of the germline and somatic stem cells in the Drosophila testis are regulated by the JAK/STAT signaling.

scientific article

Complement proteins C7 and CFH control the stemness of liver cancer cells via LSF-1

scientific article published on 23 December 2015

Curcumin inhibits PhIP induced cytotoxicity in breast epithelial cells through multiple molecular targets

scientific article published on 21 May 2015

Detection of Metastasis in a Patient-derived Orthotopic Xenograft (PDOX) Model of Undifferentiated Pleomorphic Sarcoma with Red Fluorescent Protein

scientific article published on 01 January 2019

Development and characterization of a colon PDX model that reproduces drug responsiveness and the mutation profiles of its original tumor.

scientific article

Doxorubicin-resistant pleomorphic liposarcoma with PDGFRA gene amplification is targeted and regressed by pazopanib in a patient-derived orthotopic xenograft mouse model

scientific article published on 22 May 2018

Editorial: stem cells in regenerative medicine and cancer

scientific article published on 01 January 2012

Efficacy of oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil on primary colon cancer in a patient-derived orthotopic xenograft mouse model

scientific article published on 14 August 2019

Epigenetic silencing of microRNA-373 to epithelial-mesenchymal transition in non-small cell lung cancer through IRAK2 and LAMP1 axes

scientific article

Eribulin Suppressed Cisplatinum- and Doxorubicin-resistant Recurrent Lung Metastatic Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model

scientific article published on 01 September 2019

Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation

scientific article published on 21 June 2019

Featuring the guest editors: Special issue tumor microenvironment

scientific article published on 28 May 2015

Featuring the special issue guest editor: Shree Ram Singh, Ph.D ⬇️

scientific article published on March 22, 2013

Gastric cancer stem cells: a novel therapeutic target

scientific article

Gemcitabine combined with docetaxel precisely regressed a recurrent leiomyosarcoma peritoneal metastasis in a patient-derived orthotopic xenograft (PDOX) model

scientific article published on 16 January 2019

Generating double knockout mice to model genetic intervention for diabetic cardiomyopathy in humans

scientific article

Generation and Staining of Intestinal Stem Cell Lineage in Adult Midgut ⬇️

scientific article published on January 1, 2012

Generation and molecular characterization of pancreatic cancer patient-derived xenografts reveals their heterologous nature.

scientific article published on 23 August 2016

Genome-wide RNAi screen identifies networks involved in intestinal stem cell regulation in Drosophila.

scientific article published on 19 February 2015

Germline stem cells. Preface

scientific article published on 01 January 2008

Glutamate release inhibitor, Riluzole, inhibited proliferation of human hepatocellular carcinoma cells by elevated ROS production.

scientific article published on 06 September 2016

Hair-Follicle-Associated Pluripotent (HAP) Stem Cells Encapsulated on Polyvinylidene Fluoride Membranes (PFM) Promote Functional Recovery from Spinal Cord Injury

scientific article published on 01 February 2019

Hair-follicle-associated pluripotent stem cells derived from cryopreserved intact human hair follicles sustain multilineage differentiation potential

scientific article published on 27 June 2019

Hypoxia and hypoxia inducible factors in tumor metabolism

scientific article published on 04 February 2014

Hypoxia, stem cells and bone tumor ⬇️

scientific article published on September 29, 2011

Immunohistological techniques for studying the Drosophila male germline stem cell

scientific article

Induction of Metastasis by Low-dose Gemcitabine in a Pancreatic Cancer Orthotopic Mouse Model: An Opposite Effect of Chemotherapy

scientific article published on 01 October 2019

JAK/STAT signaling regulates tissue outgrowth and male germline stem cell fate in Drosophila

scientific article

MEK inhibitor trametinib in combination with gemcitabine regresses a patient-derived orthotopic xenograft (PDOX) pancreatic cancer nude mouse model

scientific article published on 05 May 2018

Markers and Methods to Study Adult Midgut Stem Cells

scientific article published on 01 January 2018

Multipotent stem cells in the Malpighian tubules of adult Drosophila melanogaster

scientific article published on February 2009

MyD88 Regulates LPS-induced NF-ĸB/MAPK Cytokines and Promotes Inflammation and Malignancy in Colorectal Cancer Cells

scientific article published on 01 November 2019

Novel cancer gene variants and gene fusions of triple-negative breast cancers (TNBCs) reveal their molecular diversity conserved in the patient-derived xenograft (PDX) model

scientific article published on 22 April 2018

Novel targets identified by integrated cancer-stromal interactome analysis of pancreatic adenocarcinoma

scientific article published on 24 October 2019

Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model

scientific article published on 10 March 2019

Oral Recombinant Methioninase Overcomes Colorectal-cancer Liver Metastasis Resistance to the Combination of 5-Fluorouracil and Oxaliplatinum in a Patient-derived Orthotopic Xenograft Mouse Model

scientific article published on 01 September 2019

Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma

scientific article published on 01 September 2019

Oral recombinant methioninase (o-rMETase) is superior to injectable rMETase and overcomes acquired gemcitabine resistance in pancreatic cancer

scientific article published on 18 June 2018

Oral recombinant methioninase combined with oxaliplatinum and 5-fluorouracil regressed a colon cancer growing on the peritoneal surface in a patient-derived orthotopic xenograft mouse model

scientific article published on 21 September 2019

Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice

scientific article published on 23 February 2019

Patient-derived orthotopic xenograft models for cancer of unknown primary precisely distinguish chemotherapy, and tumor-targeting S. typhimurium A1-R is superior to first-line chemotherapy

scientific article published on 27 April 2018

Patient-derived orthotopic xenograft models of sarcoma

scientific article published on 19 October 2019

Patterns of sensitivity to a panel of drugs are highly individualised for undifferentiated/unclassified soft tissue sarcoma (USTS) in patient-derived orthotopic xenograft (PDOX) nude-mouse models

scientific article published on 23 August 2018

Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model

scientific article published on 03 May 2019

Peritoneal Metastases in a Patient-derived Orthotopic Xenograft (PDOX) Model of Colon Cancer Imaged Non-invasively via Red Fluorescent Protein Labeled Stromal Cells

scientific article published on 01 July 2019

Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression

scientific article published on 22 August 2019

Rap-GEF signaling controls stem cell anchoring to their niche through regulating DE-cadherin-mediated cell adhesion in the Drosophila testis

scientific article published in January 2006

Rap-GEF/Rap signaling restricts the formation of supernumerary spermathecae in Drosophila melanogaster

scientific article published in April 2006

Recombinant methioninase in combination with doxorubicin (DOX) overcomes first-line DOX resistance in a patient-derived orthotopic xenograft nude-mouse model of undifferentiated spindle-cell sarcoma.

scientific article published on 3 January 2018

Regorafenib regressed a doxorubicin-resistant Ewing's sarcoma in a patient-derived orthotopic xenograft (PDOX) nude mouse model

scientific article published on 13 February 2019

Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model

scientific article published on 01 August 2019

Spermatogonial stem cells, infertility and testicular cancer ⬇️

scientific article published on March 1, 2011

Stem Cell Niche in Tissue Homeostasis, Aging and Cancer

scientific article published on January 1, 2012

Stem cells as a therapeutic target for diabetes.

scientific article

Targeting tumor microenvironment in cancer therapy

scientific article published on 07 April 2016

Temozolomide targets and arrests a doxorubicin-resistant follicular dendritic-cell sarcoma patient-derived orthotopic xenograft mouse model

scientific article published on 03 April 2019

The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model

scientific article published on 09 July 2019

The Drosophila homolog of the human tumor suppressor gene BHD interacts with the JAK-STAT and Dpp signaling pathways in regulating male germline stem cell maintenance

scientific article published on 24 April 2006

The Nuclear Matrix Protein Megator Regulates Stem Cell Asymmetric Division through the Mitotic Checkpoint Complex in Drosophila Testes

scientific article published on 29 December 2015

The adult Drosophila gastric and stomach organs are maintained by a multipotent stem cell pool at the foregut/midgut junction in the cardia (proventriculus).

scientific article

The adult Drosophila malpighian tubules are maintained by multipotent stem cells

scientific article

The combination of gemcitabine and docetaxel arrests a doxorubicin-resistant dedifferentiated liposarcoma in a patient-derived orthotopic xenograft model

scientific article published on 11 June 2019

The combination of gemcitabine and nab-paclitaxel as a novel effective treatment strategy for undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft (PDOX) nude-mouse model

scientific article published on 04 January 2019

The combination of olaratumab with gemcitabine and docetaxel arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma in a patient-derived orthotopic xenograft mouse model

scientific article published on 30 March 2019

The combination of oral-recombinant methioninase and azacitidine arrests a chemotherapy-resistant osteosarcoma patient-derived orthotopic xenograft mouse model

scientific article published on 08 November 2019

The emerging roles of microRNAs in cancer metabolism

scientific article

The lipolysis pathway sustains normal and transformed stem cells in adult Drosophila.

scientific article published on 28 September 2016

The novel tumour suppressor Madm regulates stem cell competition in the Drosophila testis

scientific article published on 21 January 2016

Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model

scientific article published on 05 April 2019

Trabectedin arrests a doxorubicin-resistant PDGFRA-activated liposarcoma patient-derived orthotopic xenograft (PDOX) nude mouse model

Tumor suppressors Sav/Scrib and oncogene Ras regulate stem-cell transformation in adult Drosophila malpighian tubules

scientific article

Tumor-sealing Surgical Orthotopic Implantation of Human Colon Cancer in Nude Mice Induces Clinically-relevant Metastases Without Early Peritoneal Carcinomatosis

scientific article published on 01 August 2019

Tumor-targeting Salmonella typhimurium A1-R overcomes nab-paclitaxel resistance in a cervical cancer PDOX mouse model

scientific article published on 05 April 2019

Tumor-targeting Salmonella typhimurium A1-R suppressed an imatinib-resistant gastrointestinal stromal tumor with c-kit exon 11 and 17 mutations

scientific article published on 06 June 2018

Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila

scientific article published on 03 August 2016

Paulina is supported by:

About Paulina

Help