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List of works by José A Rodríguez

A Role for MMP-10 (Matrix Metalloproteinase-10) in Calcific Aortic Valve Stenosis

scientific article published on 19 March 2020

Analysis of monocitary subpopulations in relation to cardiovascular risk factors

scientific article published on 06 April 2019

Antioxidant effects of vitamins C and E, multivitamin-mineral complex and flavonoids in a model of retinal oxidative stress: the ApoE-deficient mouse.

scientific article

Antioxidant vitamins increase the collagen content and reduce MMP-1 in a porcine model of atherosclerosis: implications for plaque stabilization

scientific article published in March 2003

Association between matrix metalloproteinase-10 concentration and smoking in individuals without cardiovascular disease

scientific article published on 01 December 2008

Association between serum soluble CD40 ligand levels and mortality in patients with severe sepsis.

scientific article published on 15 March 2011

Association between serum tissue inhibitor of matrix metalloproteinase-1 levels and mortality in patients with severe brain trauma injury.

scientific article

Association of age, inflammatory markers and subclinical atherosclerosis in subjects free from cardiovascular disease

scientific article

Association of sepsis-related mortality with early increase of TIMP-1/MMP-9 ratio.

scientific article

Aterosclerosis en las enfermedades inflamatorias

scientific article published on 01 May 2007

Atheroma plaque stabilization: a new concept based on the dynamic biology of atherosclerosis

scientific article published in November 2003

C-reactive protein induces matrix metalloproteinase-1 and -10 in human endothelial cells: implications for clinical and subclinical atherosclerosis.

scientific article

CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage.

scientific article published in June 2017

Circulating TIMP-1 is associated with hematoma volume in patients with spontaneous intracranial hemorrhage

scientific article published on 25 June 2020

Combined sustained release of BMP2 and MMP10 accelerates bone formation and mineralization of calvaria critical size defect in mice

scientific article published on 01 November 2018

Design, Synthesis, and Biological Evaluation of Novel Matrix Metalloproteinase Inhibitors As Potent Antihemorrhagic Agents: From Hit Identification to an Optimized Lead

scientific article published on 25 February 2015

Dietary supplementation with vitamins C and E prevents downregulation of endothelial NOS expression in hypercholesterolemia in vivo and in vitro.

scientific article

Different expression of MMPs/TIMP-1 in human atherosclerotic lesions. Relation to plaque features and vascular bed

scientific article published on 01 October 2003

Discovery and safety profiling of a potent preclinical candidate, (4-[4-[[(3R)-3-(hydroxycarbamoyl)-8-azaspiro[4.5]decan-3-yl]sulfonyl]phenoxy]-N-methylbenzamide) (CM-352), for the prevention and treatment of hemorrhage

scientific article published on 25 February 2015

Effect of lutein and antioxidant supplementation on VEGF expression, MMP-2 activity, and ultrastructural alterations in apolipoprotein E-deficient mouse.

scientific article published on 30 April 2013

Effects of cryopreservation on the immunogenicity of porcine arterial allografts in early stages of transplant vasculopathy

scientific article published on 01 October 2005

Elevated circulating metalloproteinase 7 predicts recurrent cardiovascular events in patients with carotid stenosis: a prospective cohort study

scientific article published on 26 February 2020

Expression of inducible nitric oxide synthase in smooth muscle cells from rat penile corpora cavernosa.

scientific article published in November 1995

Fibrinógeno. Vieja proteína hemostática con nueva función: marcador no invasivo de aterosclerosis subclínica

scientific article published on 01 May 2005

Folic acid and B vitamins improve hyperhomocysteinemia-induced cardiovascular risk profile in renal transplant recipients

scientific article published on 01 May 2007

Functional MMP-10 is required for efficient tissue repair after experimental hind limb ischemia

scientific article

Functional and transcriptomic analysis of extracellular vesicles identifies calprotectin as a new prognostic marker in peripheral arterial disease (PAD)

scientific article published on 19 February 2020

High serum levels of tissue inhibitor of matrix metalloproteinase-1 during the first week of a malignant middle cerebral artery infarction in non-surviving patients

scientific article published on 18 July 2019

Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test.

scientific article published in February 2008

Independent association of matrix metalloproteinase-10, cardiovascular risk factors and subclinical atherosclerosis

scientific article published on 16 October 2006

Induction of TIMP-1 expression in rat hepatic stellate cells and hepatocytes: a new role for homocysteine in liver fibrosis

scientific article published on 01 September 1999

Influence of the 4G/5G PAI-1 genotype on angiotensin II-stimulated human endothelial cells and in patients with hypertension.

scientific article

Inner ear drug delivery through a cochlear implant: Pharmacokinetics in a Macaque experimental model

scientific article published in 2021

Lack of TAFI increases brain damage and microparticle generation after thrombolytic therapy in ischemic stroke.

scientific article

MMP-10 is Increased in Early Stage Diabetic Kidney Disease and can be Reduced by Renin-Angiotensin System Blockade

scientific article published on 08 January 2020

MMP-10 is required for efficient muscle regeneration in mouse models of injury and muscular dystrophy.

scientific article

MMP10 Promotes Efficient Thrombolysis After Ischemic Stroke in Mice with Induced Diabetes

scientific article published on 27 July 2018

Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis

scientific article

Matrix metalloproteinase 10 is associated with disease severity and mortality in patients with peripheral arterial disease

scientific article published on 23 October 2014

Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification

scientific article published on 19 September 2018

Matrix metalloproteinase-10 effectively reduces infarct size in experimental stroke by enhancing fibrinolysis via a thrombin-activatable fibrinolysis inhibitor-mediated mechanism.

scientific article

Matrix metalloproteinase-10 expression is induced during hepatic injury and plays a fundamental role in liver tissue repair

scientific article published on 16 October 2013

Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation

scientific article published on 17 September 2009

Matrix metalloproteinase-9, -10, and tissue inhibitor of matrix metalloproteinases-1 blood levels as biomarkers of severity and mortality in sepsis.

scientific article published on 02 October 2009

Metaloproteasas, remodelado vascular y syndromes aterotrombóticos

scientific article published on 01 September 2007

Monocyte cyclooxygenase-2 activity: a new therapeutic target for atherosclerosis?

scientific article (publication date: August 2005)

New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator

scientific article published on 3 April 2017

Persistently high circulating tissue inhibitor of matrix metalloproteinase-1 levels in non-survivor brain trauma injury patients

scientific article published on 19 February 2019

Phagocytic NADPH Oxidase-Dependent Superoxide Production Stimulates Matrix Metalloproteinase-9

scientific article published on 28 December 2006

Phenotypic Screening To Discover Novel Chemical Series as Efficient Antihemorrhagic Agents

scientific article published on 16 April 2018

Polimorfismo 4G/5G del PAI-1 en el síndrome metabólico

scientific article published on 01 February 2006

Protective effect of the G-765C COX-2 polymorphism on subclinical atherosclerosis and inflammatory markers in asymptomatic subjects with cardiovascular risk factors.

scientific article published on 3 February 2006

Reduced high-density lipoprotein cholesterol: A valuable, independent prognostic marker in peripheral arterial disease

scientific article published on 27 June 2017

Selective increase of cardiomyocyte derived extracellular vesicles after experimental myocardial infarction and functional effects on the endothelium

scientific article published on 01 August 2018

Serum levels of matrix metalloproteinase-10 are associated with the severity of atherosclerosis in patients with chronic kidney disease

scientific article published in December 2010

Serum tissue inhibitor of matrix metalloproteinase-1 levels are associated with mortality in patients with malignant middle cerebral artery infarction

scientific article published on 11 July 2015

Stromelysin-2 (MMP-10) deficiency does not affect adipose tissue formation in a mouse model of nutritionally induced obesity

scientific article published on 02 September 2009

The 372 T/C genetic polymorphism of TIMP-1 is associated with serum levels of TIMP-1 and survival in patients with severe sepsis.

scientific article published on 25 May 2013

The 4G/5G PAI-1 polymorphism influences the endothelial response to IL-1 and the modulatory effect of pravastatin.

scientific article

The CXCR4/SDF1 axis improves muscle regeneration through MMP-10 activity

scientific article published on 14 March 2014

Tissue-specific PAI-1 gene expression and glycosylation pattern in insulin-resistant old rats.

scientific article published on 23 September 2009

Torasemide Inhibits Angiotensin II–Induced Vasoconstriction and Intracellular Calcium Increase in the Aorta of Spontaneously Hypertensive Rats

scientific article published in July 1999

Trimethylamine-N-Oxide (TMAO) Predicts Cardiovascular Mortality in Peripheral Artery Disease

scientific article published on 30 October 2019

Up-regulation of the levels of androgen receptor and its mRNA by androgens in smooth-muscle cells from rat penis

scientific article published on 01 January 1993

Vitamins C and E downregulate vascular VEGF and VEGFR-2 expression in apolipoprotein-E-deficient mice.

scientific article

Vitamins C and E prevent endothelial VEGF and VEGFR-2 overexpression induced by porcine hypercholesterolemic LDL.

scientific article published in February 2005

Vitamins C and e reduce retinal oxidative stress and nitric oxide metabolites and prevent ultrastructural alterations in porcine hypercholesterolemia

scientific article published in April 2005

Vulnerable plaque versus vulnerable patient: emerging blood biomarkers for risk stratification.

scientific article published on September 2007

[Role of antioxidants in the prevention of cardiovascular disease]

scientific article published on 01 May 2001

proMetalloproteinase-10 is associated with brain damage and clinical outcome in acute ischemic stroke.

scientific article published on August 2013

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