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List of works by Alain Brunelle

A layered structure in the organic envelopes of the prismatic layer of the shell of the pearl oyster Pinctada margaritifera (Mollusca, Bivalvia).

scientific article

A new safety concern for glaucoma treatment demonstrated by mass spectrometry imaging of benzalkonium chloride distribution in the eye, an experimental study in rabbits

scientific article

An Integrative Approach to Decipher the Chemical Antagonism between the Competing Endophytes Paraconiothyrium variabile and Bacillus subtilis.

scientific article

Animal urine as painting materials in African rock art revealed by cluster ToF-SIMS mass spectrometry imaging.

scientific article

Argon cluster ion source evaluation on lipid standards and rat brain tissue samples

scientific article published on 07 August 2013

Atmospheric pressure photoionization as a powerful tool for large-scale lipidomic studies

scientific article

Biological tissue imaging with time-of-flight secondary ion mass spectrometry and cluster ion sources

scientific article published in August 2005

Biomedical studies by TOF-SIMS imaging.

scientific article

Biosynthetic investigation of γ-lactones in Sextonia rubra wood using in situ TOF-SIMS MS/MS imaging to localize and characterize biosynthetic intermediates

scientific article published in Scientific Reports

Changes of phospholipid composition within the dystrophic muscle by matrix-assisted laser desorption/ionization mass spectrometry and mass spectrometry imaging.

scientific article published in January 2004

Characterization of alpha-parvalbumin on muscle tissue sections by in situ calcium attachment

scientific article published on 01 January 2007

Chemical imaging on liver steatosis using synchrotron infrared and ToF-SIMS microspectroscopies

scientific article

Choline-Containing Phospholipids in Microdissected Human Alzheimer’S Disease Brain Senile Plaque Versus Neuropil ⬇️

scientific article published on September 1, 2012

Cluster TOF-SIMS imaging as a tool for micrometric histology of lipids in tissue

scientific article published on 21 November 2013

Cluster TOF-SIMS imaging of human skin remains: analysis of a South-Andean mummy sample

scientific article published in March 2012

Comprehensive characterization of Annonaceous acetogenins within a complex extract by HPLC-ESI-LTQ-Orbitrap® using post-column lithium infusion

scientific article published on 01 November 2012

Correlative mass spectrometry imaging, applying time-of-flight secondary ion mass spectrometry and atmospheric pressure matrix-assisted laser desorption/ionization to a single tissue section.

scientific article published on 3 November 2017

Dual Beam Depth Profiling and Imaging with Argon and Bismuth Clusters of Prenylated Stilbenes on Glandular Trichomes of Macaranga vedeliana.

scientific article

Environmentally Friendly Procedure Based on Supercritical Fluid Chromatography and Tandem Mass Spectrometry Molecular Networking for the Discovery of Potent Antiviral Compounds from Euphorbia semiperfoliata.

scientific article published on 19 September 2017

Fatty acids penetration into human skin ex vivo: A TOF-SIMS analysis approach

scientific article published on 2 March 2017

Identification of ritual blood in African artifacts using TOF-SIMS and synchrotron radiation microspectroscopies.

scientific article

Identification of the environmental neurotoxins annonaceous acetogenins in an Annona cherimolia Mill. Alcoholic Beverage Using HPLC-ESI-LTQ-Orbitrap.

scientific article

Impact of inhaled nitric oxide on the sulfatide profile of neonatal rat brain studied by TOF-SIMS imaging

scientific article

Impact of rhizosphere factors on cyclic lipopeptide signature from the plant beneficial strain Bacillus amyloliquefaciensS499

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Improvement of biological time-of-flight-secondary ion mass spectrometry imaging with a bismuth cluster ion source

scientific article published in October 2005

In situ lipidomic analysis of nonalcoholic fatty liver by cluster TOF-SIMS imaging

scientific article

In situ localisation and quantification of surfactins in a Bacillus subtilis swarming community by imaging mass spectrometry.

scientific article

In situ primary metabolites localization on a rat brain section by chemical mass spectrometry imaging.

scientific article

Insights into the MALDI Process after Matrix Deposition by Sublimation Using 3D ToF-SIMS Imaging

scientific article published on 3 January 2018

Ion-beam mixing induced by atomic and cluster bombardment in the electronic stopping-power regime

scientific article published on 01 June 1996

Kidney Lipidomics by Mass Spectrometry Imaging: A Focus on the Glomerulus ⬇️

scientific article published on 01 April 2019

Lipid cartography of atherosclerotic plaque by cluster-TOF-SIMS imaging

scientific article published on 21 November 2006

Lipid imaging by gold cluster time-of-flight secondary ion mass spectrometry: application to Duchenne muscular dystrophy.

scientific article published on 16 April 2005

Lipid imaging with cluster time-of-flight secondary ion mass spectrometry

scientific article published on 07 September 2008

Lipid mapping in human dystrophic muscle by cluster-time-of-flight secondary ion mass spectrometry imaging

scientific article published on 17 November 2007

Lipid mapping of colonic mucosa by cluster TOF-SIMS imaging and multivariate analysis in cftr knockout mice.

scientific article

Lipidomic and spatio-temporal imaging of fat by mass spectrometry in mice duodenum during lipid digestion

scientific article

Localisation and quantification of benzalkonium chloride in eye tissue by TOF-SIMS imaging and liquid chromatography mass spectrometry.

scientific article published on 21 February 2013

Localization of flavonoids in seeds by cluster time-of-flight secondary ion mass spectrometry imaging

scientific article published on 01 March 2010

Localized lipidomics in cystic fibrosis: TOF-SIMS imaging of lungs from Pseudomonas aeruginosa-infected mice

scientific article published on 07 February 2014

Low doses of arginine butyrate derivatives improve dystrophic phenotype and restore membrane integrity in DMD models.

scientific article published on 6 March 2014

MALDI imaging and structural analysis of rat brain lipid negative ions with 9-aminoacridine matrix.

scientific article

MALDI imaging mass spectrometry of lipids by adding lithium salts to the matrix solution.

scientific article

MALDI mass spectrometry imaging of 1-methyl-4-phenylpyridinium (MPP+) in mouse brain.

scientific article

MALDI mass spectrometry imaging of lipids and primary metabolites on rat brain sections

scientific article

MALDI reveals membrane lipid profile reversion in MDX mice

scientific article

Mapping Dicorynia guianensis Amsh. wood constituents by submicron resolution cluster-TOF-SIMS imaging

scientific article published on June 2016

Mass spectrometry imaging of biological tissue: an approach for multicenter studies

scientific article

Mass spectrometry imaging of rat brain sections: nanomolar sensitivity with MALDI versus nanometer resolution by TOF-SIMS.

scientific article published on 27 August 2009

Mass spectrometry imaging: Towards a lipid microscope?

scientific article

Metabolism dysregulation induces a specific lipid signature of nonalcoholic steatohepatitis in patients

scientific article

Method development for quantification of the environmental neurotoxin annonacin in Rat plasma by UPLC-MS/MS and application to a pharmacokinetic study.

scientific article published on 30 September 2015

Micrometric molecular histology of lipids by mass spectrometry imaging.

scientific article

Multimodal Imaging Based on Vibrational Spectroscopies and Mass Spectrometry Imaging Applied to Biological Tissue: A Multiscale and Multiomics Review

scientific article published on 30 November 2020

Multimodal spectroscopy combining time-of-flight-secondary ion mass spectrometry, synchrotron-FT-IR, and synchrotron-UV microspectroscopies on the same tissue section

scientific article published on 01 May 2010

Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech

scientific article

Neuroprotective effects of a brain permeant 6-aminoquinoxaline derivative in cell culture conditions that model the loss of dopaminergic neurons in Parkinson disease.

scientific article

Optimization and validation of a label-free MRM method for the quantification of cytochrome P450 isoforms in biological samples.

scientific article

Poly(amide ester)s from 2,6-pyridinedicarboxylic acid and ethanolamine derivatives: identification of macrocycles by matrix-assisted laser desorption/ionization mass spectrometry

scientific article

Pores formation on cell membranes by hederacolchiside A1 leads to a rapid release of proteins for cytosolic subproteome analysis.

scientific article

Quantification of the environmental neurotoxin annonacin in Rat brain by UPLC-MS/MS.

scientific article published on 4 April 2016

Quantification of tocopherols and tocotrienols in soybean oil by supercritical-fluid chromatography coupled to high-resolution mass spectrometry

scientific article

Radial distribution of wood extractives in European larch Larix decidua by TOF-SIMS imaging.

scientific article published on 10 March 2018

Recent advances in biological tissue imaging with Time-of-flight Secondary Ion Mass Spectrometry: polyatomic ion sources, sample preparation, and applications

scientific article published on January 2007

Shell layers of the black-lip pearl oyster Pinctada margaritifera: matching microstructure and composition

article

Skin Penetration Enhancement by Natural Oils for Dihydroquercetin Delivery

scientific article published on 12 September 2017

Structural Characterisation of Acetogenins from Annona muricata by Supercritical Fluid Chromatography Coupled to High-Resolution Tandem Mass Spectrometry

scientific article

Structural analysis of secondary ions by post-source decay in time-of-flight secondary ion mass spectrometry

scientific article published in January 2006

Studying the penetration of fatty acids into human skin by ex vivo TOF-SIMS imaging.

scientific article published on 6 February 2013

Synchrotron SOLEIL radiation reveals discrete biochemical changes in human steatosis

scientific article published in November 2009

TOF-SIMS imaging of lipids on rat brain sections

scientific article published in January 2015

Tandem Mass Spectrometry Imaging and in Situ Characterization of Bioactive Wood Metabolites in Amazonian Tree Species Sextonia rubra

scientific article published on 08 June 2018

Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients.

scientific article published on 7 September 2012

Time-of-flight secondary ion mass spectrometry imaging demonstrates the specific localization of deca-bromo-diphenyl-ether residues in the ovaries and adrenal glands of exposed rats

scientific article published on 7 July 2010

Time-of-flight secondary ion mass spectrometry imaging of biological samples with delayed extraction for high mass and high spatial resolutions.

scientific article published on July 2015

Tissue molecular ion imaging by gold cluster ion bombardment

scientific article published on 01 March 2004

Tracks in metals by MeV fullerenes

scientific article published on 01 February 1995

Ultra performance liquid chromatography - mass spectrometry studies of formalin-induced alterations of human brain lipidome

scientific article published in October 2014

Unexpected materials in a Rembrandt painting characterized by high spatial resolution cluster-TOF-SIMS imaging.

scientific article

Validation data for the quantification of the Annonaceous acetogenin annonacin in Rat brain by UPLC-MS/MS.

scientific article

Very large gold and silver sputtering yields induced by keV to MeV energy Au n clusters ( n = 1 – 1 3 )

scientific article

Wax finishing in Roman polychrome statuary: Ganosis on the colossal head from Dougga (Tunisia)

scientific article published in 2021

What more can TOF-SIMS bring than other MS imaging methods?

scientific article published on 19 February 2016

imzML--a common data format for the flexible exchange and processing of mass spectrometry imaging data.

scientific article

Étude pluridisciplinaire du squelette de rhinocéros laineux, Coelodonta antiquitatis (Blumenbach, 1799), de l’Institut de paléontologie humaine (Paris, France)

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