Search filters

List of works by Gregory Fairn

7-Ketocholesterol Impairs Phagocytosis and Efferocytosis via Dysregulation of Phosphatidylinositol 4,5-bisphosphate

scientific article published on 24 April 2018

A Chemogenomic Screen in Saccharomyces cerevisiae Uncovers a Primary Role for the Mitochondria in Farnesol Toxicity and Its Regulation by the Pkc1 Pathway

scientific article published in Journal of Biological Chemistry

A weak base-generating system suitable for selective manipulation of lysosomal pH.

scientific article published on 6 September 2011

Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference

scientific article

Akt-ing Up Just About Everywhere: Compartment-Specific Akt Activation and Function in Receptor Tyrosine Kinase Signaling

scientific article published on 03 May 2019

An ATG16L1-dependent pathway promotes plasma membrane repair and limits Listeria monocytogenes cell-to-cell spread

scientific article published on 26 November 2018

An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis

scientific article

Bem3, a Cdc42 GTPase-activating protein, traffics to an intracellular compartment and recruits the secretory Rab GTPase Sec4 to endomembranes

scientific article

Both the PH domain and N-terminal region of oxysterol-binding protein related protein 8S are required for localization to PM-ER contact sites

scientific article published on 31 January 2018

Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages

scientific article (publication date: 2013)

CD36 mediates albumin transcytosis by dermal but not lung microvascular endothelial cells: role in fatty acid delivery

scientific article published on 31 January 2019

CD44 Antibody Inhibition of Macrophage Phagocytosis Targets Fcγ Receptor- and Complement Receptor 3-Dependent Mechanisms.

scientific article published on 04 March 2016

Cell biology. A one-sided signal

scientific article published in April 2008

Cell biology. Precursor or charge supplier?

scientific article published on 01 August 2012

Cleavage furrow organization requires PIP(2)-mediated recruitment of anillin.

scientific article

Comment on 'Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol'

scientific article published on 13 November 2018

Complementary probes reveal that phosphatidylserine is required for the proper transbilayer distribution of cholesterol.

scientific article

Contribution of phosphatidylserine to membrane surface charge and protein targeting during phagosome maturation.

scientific article published on June 2009

Cresyl violet: a superior fluorescent lysosomal marker

scientific article published on 13 September 2016

Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation

scientific article

Diacylglycerol kinases terminate diacylglycerol signaling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation.

scientific article published in February 2014

Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides

scientific article published on 20 June 2019

Emerging roles of the oxysterol-binding protein family in metabolism, transport, and signaling.

scientific article published on January 2008

Enforced expression of phosphatidylinositol 4-phosphate 5-kinase homolog alters PtdIns(4,5)P2 distribution and the localization of small G-proteins

scientific article published on 15 October 2019

Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis

scientific article published on 5 April 2016

High-resolution mapping reveals topologically distinct cellular pools of phosphatidylserine

scientific article

How nascent phagosomes mature to become phagolysosomes

scientific article published on 03 May 2012

Induction of spontaneous curvature and endocytosis: Unwanted consequences of cholesterol extraction using methyl-β-Cyclodextrin

scientific article published on 13 March 2018

Inhibition of Acid Sphingomyelinase Depletes Cellular Phosphatidylserine and Mislocalizes K-Ras from the Plasma Membrane.

scientific article

Integrity under stress: Host membrane remodelling and damage by fungal pathogens

scientific article published on 07 March 2019

Is basic science disappearing from medicine? The decline of biomedical research in the medical literature

scientific article published on 14 October 2015

Localization of lipid raft proteins to the plasma membrane is a major function of the phospholipid transfer protein Sec14.

scientific article

Membrane curvature induced by proximity of anionic phospholipids can initiate endocytosis

scientific article published on 9 November 2017

Membrane metabolism mediated by Sec14 family members influences Arf GTPase activating protein activity for transport from the trans-Golgi

scientific article

Mesoscale organization of domains in the plasma membrane - beyond the lipid raft

scientific article published on 18 February 2018

Molecular probes to visualize the location, organization and dynamics of lipids.

scientific article published in September 2014

Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis

scientific article

PI(4,5)P2 controls plasma membrane PI4P and PS levels via ORP5/8 recruitment to ER-PM contact sites.

scientific article

PPAR-delta modulates membrane cholesterol and cytokine signaling in malignant B cells

scientific article published on 30 May 2017

Palmitoylation of NOD1 and NOD2 is required for bacterial sensing

scientific article published on 24 October 2019

Perfringolysin O Theta Toxin as a Tool to Monitor the Distribution and Inhomogeneity of Cholesterol in Cellular Membranes

scientific article

Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling

scientific article published on 30 September 2019

Phosphatidic acid is required for the constitutive ruffling and macropinocytosis of phagocytes

scientific article

Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis

scientific article published on 31 October 2017

Phosphatidylserine is polarized and required for proper Cdc42 localization and for development of cell polarity

scientific article published on 02 October 2011

Phosphoinositide 3-kinase enables phagocytosis of large particles by terminating actin assembly through Rac/Cdc42 GTPase-activating proteins

scientific article

Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways.

scientific article

Rapamycin-based inducible translocation systems for studying phagocytosis.

scientific article published on January 2011

Regulation of phosphoinositide levels by the phospholipid transfer protein Sec14p controls Cdc42p/p21-activated kinase-mediated cell cycle progression at cytokinesis

scientific article

Staurosporines decrease ORMDL proteins and enhance sphingomyelin synthesis resulting in depletion of plasmalemmal phosphatidylserine

scientific article published on 2 November 2016

Studying phospholipid metabolism using yeast systematic and chemical genetics

scientific article published in June 2005

The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.

scientific article

The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function.

scholarly article

The roles of the human lipid-binding proteins ORP9S and ORP10S in vesicular transport

scientific article published on 01 October 2005

The yeast oxysterol binding protein Kes1 maintains sphingolipid levels

scientific article

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis

scientific article published on 20 January 2017

Paulina is supported by:

About Paulina

Help