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List of works by Pierre Sonveaux

(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice

scientific article published on 4 December 2017

A Fast Hydrogen Sulfide-Releasing Donor Increases the Tumor Response to Radiotherapy

scientific article published on 18 December 2015

A mitochondrial switch promotes tumor metastasis.

scientific article

Activated macrophages as a novel determinant of tumor cell radioresponse: the role of nitric oxide-mediated inhibition of cellular respiration and oxygen sparing.

scientific article published on April 2010

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer

scientific article

Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

scientific article

Antitumor activity of 7-aminocarboxycoumarin derivatives, a new class of potent inhibitors of lactate influx but not efflux

scientific article published on 26 March 2014

Antitumor effects of in vivo caveolin gene delivery are associated with the inhibition of the proangiogenic and vasodilatory effects of nitric oxide.

scientific article published on 28 December 2004

Application of Electron Paramagnetic Resonance (EPR) Oximetry to Monitor Oxygen in Wounds in Diabetic Models

scientific article published on 14 December 2015

Assessment of melanoma extent and melanoma metastases invasion using electron paramagnetic resonance and bioluminescence imaging.

scientific article

Cancer metabolism in space and time: Beyond the Warburg effect

scientific article published on 3 February 2017

Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.

scientific article

Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis

scientific article published on 17 June 2004

Caveolin-1 is critical for the maturation of tumor blood vessels through the regulation of both endothelial tube formation and mural cell recruitment

scientific article

Combined effects of PLGA and vascular endothelial growth factor promote the healing of non-diabetic and diabetic wounds

scientific article published on 31 July 2015

Common responses of tumors and wounds to hypoxia.

scientific article published on March 2015

Comparison of different methods for measuring the superoxide radical by EPR spectroscopy in buffer, cell lysates and cells

scientific article published on 01 October 2018

Contribution of macrophages in the contrast loss in iron oxide-based MRI cancer cell tracking studies

scientific article

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses.

scientific article published on 22 September 2017

Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro.

scientific article published on January 2016

Early reoxygenation in tumors after irradiation: determining factors and consequences for radiotherapy regimens using daily multiple fractions

scientific article

Electron paramagnetic resonance as a sensitive tool to assess the iron oxide content in cells for MRI cell labeling studies.

scientific article

Endothelin-1 is a critical mediator of myogenic tone in tumor arterioles: implications for cancer treatment

scientific article

Energy metabolism in osteoclast formation and activity

scientific article published on 30 August 2016

Evidence of metabolic activity during low-temperature ovarian tissue preservation in different media

scientific article published on 04 September 2020

Ffar2 expression regulates leukaemic cell growth in vivo.

scientific article published on 5 September 2017

Fitter Mitochondria Are Associated With Radioresistance in Human Head and Neck SQD9 Cancer Cells

scientific article published on 13 March 2020

Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose

scientific article

Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration

scientific article published on 28 October 2013

Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism

scientific article published on 17 October 2016

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

scientific article

Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells

scientific article

In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance.

scientific article

Influence of cell detachment on the respiration rate of tumor and endothelial cells

scientific article

Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.

scientific article published on 2 November 2015

Insulin increases the sensitivity of tumors to irradiation: involvement of an increase in tumor oxygenation mediated by a nitric oxide-dependent decrease of the tumor cells oxygen consumption

scientific article

Interrogating the Lactate Dehydrogenase Tetramerization Site Using (Stapled) Peptides

scientific article published on 06 April 2020

Involvement of nitric oxide in iodine deficiency-induced microvascular remodeling in the thyroid gland: role of nitric oxide synthase 3 and ryanodine receptors

scientific article

Iodine deficiency induces a thyroid stimulating hormone-independent early phase of microvascular reshaping in the thyroid

scientific article

Iodine-deficiency-induced long lasting angiogenic reaction in thyroid cancers occurs via a vascular endothelial growth factor-hypoxia inducible factor-1-dependent, but not a reactive oxygen species-dependent, pathway

scientific article

Irradiation promotes Akt-targeting therapeutic gene delivery to the tumor vasculature

scientific article published on 2 February 2007

Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer

scientific journal article

Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells

scientific article published in 2012

Lactate does not activate NF-κB in oxidative tumor cells

scientific article

Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis

scientific article published on 7 February 2011

Lactate promotes glutamine uptake and metabolism in oxidative cancer cells

scientific article published on 4 December 2015

Lactate stimulates CA IX expression in normoxic cancer cells.

scientific article

Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice.

scientific article published on 3 June 2012

Loss of CC3/TIP30 allows tumor cells to cope with low glucose ⬇️

scientific article published on 01 February 2011

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases

scientific article published on 30 August 2017

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway

scientific article

Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism

scientific article

MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity

scientific article published on 16 March 2022

MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice

scientific article published in 2022

Monocarboxylate Transporter 1 Deficiency Impacts CD8 <sup>+</sup> T Lymphocytes Proliferation and Recruitment to Adipose Tissue During Obesity

scientific article published in 2021

Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter

scientific article published on 21 August 2017

Monocarboxylate transporters in the brain and in cancer.

scientific article published on 15 March 2016

Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.

scientific article published on March 2014

Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo

scientific article

Multiple biological activities of lactic acid in cancer: influences on tumor growth, angiogenesis and metastasis.

scientific article published on January 2012

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

scientific article

Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption

scientific article published in May 2004

Nitric oxide delivery to cancer: why and how?

scientific article published on 17 January 2009

Nitric oxide-mediated increase in tumor blood flow and oxygenation of tumors implanted in muscles stimulated by electric pulses

scientific article

Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism

scientific article

Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells

scientific article published in 2021

Optimization of tumor radiotherapy with modulators of cell metabolism: toward clinical applications

scientific article published on October 2013

Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.

scientific article published on 5 May 2005

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing

scientific article published on 27 August 2014

Paclitaxel-loaded micelles enhance transvascular permeability and retention of nanomedicines in tumors.

scientific article

Paving the way for therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide.

scientific article published on 29 October 2014

Proton channels and exchangers in cancer

scientific article

Provascular strategy: targeting functional adaptations of mature blood vessels in tumors to selectively influence the tumor vascular reactivity and improve cancer treatment

scientific article published on 03 March 2008

ROS and radiotherapy: more we care

scientific article published on 27 March 2017

Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors

scientific article

Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation.

scientific article published on 21 May 2013

Regulation of HIF-1alpha stability through S-nitrosylation

scientific article

Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors.

scientific article

Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.

scientific article published on 9 July 2014

Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery.

scientific article published in June 2006

Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells

scientific article published on 8 October 2013

Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing

scientific article published on 05 December 2013

Synthesis and characterization of a 5-membered ring cyclic hydroxylamine coupled to triphenylphosphonium to detect mitochondrial superoxide by EPR spectrometry

scientific article published on 19 November 2019

Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells

scientific article

Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth

scientific article published on 01 April 2007

Targeting Tumor Perfusion and Oxygenation to Improve the Outcome of Anticancer Therapy1 ⬇️

scientific article published on May 21, 2012

Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.

scientific article

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment.

scientific article published in January 2005

The acidic tumor microenvironment promotes the reconversion of nitrite into nitric oxide: towards a new and safe radiosensitizing strategy.

scientific article published in May 2008

Transport and peripheral bioactivities of nitrogen oxides carried by red blood cell hemoglobin: role in oxygen delivery.

scientific article published on April 2007

Tumor reoxygenation following administration of Mitogen-Activated Protein Kinase inhibitors: a rationale for combination with radiation therapy.

scientific article

Tumour-specific metabolic adaptation to acidosis is coupled to epigenetic stability in osteosarcoma cells

scientific article published on 15 March 2016

[Cancer: when recycling becomes a weakness].

scientific article published in April 2009

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