List of works - Luciana Esposito

A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair

scientific article published on 28 September 2019

AlphaFold-Predicted Structures of KCTD Proteins Unravel Previously Undetected Relationships among the Members of the Family

scientific article published on 10 December 2021

Alphafold Predictions Provide Insights into the Structural Features of the Functional Oligomers of All Members of the KCTD Family

scientific article published in 2022

Biochemical and structural characterization of recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius highly enantioselective on diaryl diketone benzil

scientific article

Bond distances in polypeptide backbones depend on the local conformation

scientific article published on 14 May 2015

Correlation between omega and psi dihedral angles in protein structures.

scientific article

Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus

scientific article

Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution

scientific article

Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability

scientific article

Cullin3-BTB interface: a novel target for stapled peptides

scientific article published on 7 April 2015

Deamidation in proteins: the crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67

scientific article

Dissection of Factors Affecting the Variability of the Peptide Bond Geometry and Planarity.

scientific article

Dynamics and stability of amyloid-like steric zipper assemblies with hydrophobic dry interfaces.

scientific article published in December 2009

Effect of C5-Methylation of Cytosine on the Photoreactivity of DNA: A Joint Experimental and Computational Study of TCG Trinucleotides

article published in 2014

Effect of C5-Methylation of Cytosine on the UV-Induced Reactivity of Duplex DNA: Conformational and Electronic Factors

scientific article

Excited State Pathways Leading to Formation of Adenine Dimers

scientific article published on 18 May 2016

Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures.

scientific article

Factors affecting the amplitude of the τ angle in proteins: a revisitation

scientific article published on 28 June 2017

Five human phenylalanine hydroxylase proteins identified in mild hyperphenylalaninemia patients are disease-causing variants.

scientific article

Functional analysis of melanocortin-4-receptor mutants identified in severely obese subjects living in Southern Italy.

scientific article published on 7 March 2010

Functional and structural characterization of novel mutations and genotype-phenotype correlation in 51 phenylalanine hydroxylase deficient families from Southern Italy

scientific article

Insight into ribonuclease A domain swapping by molecular dynamics unfolding simulations

scientific article

Insights into stability and toxicity of amyloid-like oligomers by replica exchange molecular dynamics analyses.

scientific article

Insights into structure, stability, and toxicity of monomeric and aggregated polyglutamine models from molecular dynamics simulations.

scientific article published on 30 January 2008

Interplay between peptide bond geometrical parameters in nonglobular structural contexts.

scientific article

Local Backbone Geometry Plays a Critical Role in Determining Conformational Preferences of Amino Acid Residues in Proteins

scientific article published in 2022

Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations

scientific article published on 18 April 2014

Multiple Electronic and Structural Factors Control Cyclobutane Pyrimidine Dimer and 6-4 Thymine-Thymine Photodimerization in a DNA Duplex

scientific article published on 15 August 2017

Peptide bond distortions from planarity: new insights from quantum mechanical calculations and peptide/protein crystal structures

scientific article published on 16 September 2011

Polyglutamine repeats and β-helix structure: Molecular dynamics study

article

Probing the peptidylglycine alpha-hydroxylating monooxygenase active site with novel 4-phenyl-3-butenoic acid based inhibitors

scientific article published on September 2010

Protein Crystal Growth in the Advanced Protein Crystallization Facility on the LMS Mission: a Comparison of Sulfolobus solfataricus Alcohol Dehydrogenase Crystals Grown on the Ground and in Microgravity

scientific article published on 01 May 1998

Recent advances in atomic resolution protein crystallography

scientific article

Role of loops connecting secondary structure elements in the stabilization of proteins isolated from thermophilic organisms

scientific article published on July 2013

Role of the conformational versatility of the neurotrophin N-terminal regions in their recognition by Trk receptors.

scientific article published on October 2010

Role of tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase

scientific article

Stability of single sheet GNNQQNY aggregates analyzed by replica exchange molecular dynamics: Antiparallel versus parallel association

scientific article published on 18 October 2008

Structural study of a single-point mutant of Sulfolobus solfataricus alcohol dehydrogenase with enhanced activity

scientific article (publication date: 27 March 2003)

Studying the excited electronic states of guanine rich DNA quadruplexes by quantum mechanical methods: main achievements and perspectives

scientific article published on 07 April 2020

The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension

scientific article

The determinants of bond angle variability in protein/peptide backbones: A comprehensive statistical/quantum mechanics analysis.

scientific article

The intrinsic stability of the human prion β-sheet region investigated by molecular dynamics

scientific article published on 09 August 2012

The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima

scientific article published on 05 November 2019

The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: hydration and sterochemical analysis

scientific article

List of works by Luciana Esposito

A Functional Analysis of the Unclassified Pro2767Ser BRCA2 Variant Reveals Its Potential Pathogenicity that Acts by Hampering DNA Binding and Homology-Mediated DNA Repair

AlphaFold-Predicted Structures of KCTD Proteins Unravel Previously Undetected Relationships among the Members of the Family

Alphafold Predictions Provide Insights into the Structural Features of the Functional Oligomers of All Members of the KCTD Family

Biochemical and structural characterization of recombinant short-chain NAD(H)-dependent dehydrogenase/reductase from Sulfolobus acidocaldarius highly enantioselective on diaryl diketone benzil

Bond distances in polypeptide backbones depend on the local conformation

Correlation between omega and psi dihedral angles in protein structures.

Crystal structure of a ternary complex of the alcohol dehydrogenase from Sulfolobus solfataricus

Crystal structure of the alcohol dehydrogenase from the hyperthermophilic archaeon Sulfolobus solfataricus at 1.85 A resolution

Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability

Cullin3-BTB interface: a novel target for stapled peptides

Deamidation in proteins: the crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67

Dissection of Factors Affecting the Variability of the Peptide Bond Geometry and Planarity.

Dynamics and stability of amyloid-like steric zipper assemblies with hydrophobic dry interfaces.

Effect of C5-Methylation of Cytosine on the Photoreactivity of DNA: A Joint Experimental and Computational Study of TCG Trinucleotides

Effect of C5-Methylation of Cytosine on the UV-Induced Reactivity of Duplex DNA: Conformational and Electronic Factors

Excited State Pathways Leading to Formation of Adenine Dimers

Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures.

Factors affecting the amplitude of the τ angle in proteins: a revisitation

Five human phenylalanine hydroxylase proteins identified in mild hyperphenylalaninemia patients are disease-causing variants.

Functional analysis of melanocortin-4-receptor mutants identified in severely obese subjects living in Southern Italy.

Functional and structural characterization of novel mutations and genotype-phenotype correlation in 51 phenylalanine hydroxylase deficient families from Southern Italy

Insight into ribonuclease A domain swapping by molecular dynamics unfolding simulations

Insights into stability and toxicity of amyloid-like oligomers by replica exchange molecular dynamics analyses.

Insights into structure, stability, and toxicity of monomeric and aggregated polyglutamine models from molecular dynamics simulations.

Interplay between peptide bond geometrical parameters in nonglobular structural contexts.

Local Backbone Geometry Plays a Critical Role in Determining Conformational Preferences of Amino Acid Residues in Proteins

Molecular recognition of Cullin3 by KCTDs: Insights from experimental and computational investigations

Multiple Electronic and Structural Factors Control Cyclobutane Pyrimidine Dimer and 6-4 Thymine-Thymine Photodimerization in a DNA Duplex

Peptide bond distortions from planarity: new insights from quantum mechanical calculations and peptide/protein crystal structures

Polyglutamine repeats and β-helix structure: Molecular dynamics study

Probing the peptidylglycine alpha-hydroxylating monooxygenase active site with novel 4-phenyl-3-butenoic acid based inhibitors

Protein Crystal Growth in the Advanced Protein Crystallization Facility on the LMS Mission: a Comparison of Sulfolobus solfataricus Alcohol Dehydrogenase Crystals Grown on the Ground and in Microgravity

Recent advances in atomic resolution protein crystallography

Role of loops connecting secondary structure elements in the stabilization of proteins isolated from thermophilic organisms

Role of the conformational versatility of the neurotrophin N-terminal regions in their recognition by Trk receptors.

Role of tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase

Stability of single sheet GNNQQNY aggregates analyzed by replica exchange molecular dynamics: Antiparallel versus parallel association

Structural study of a single-point mutant of Sulfolobus solfataricus alcohol dehydrogenase with enhanced activity

Studying the excited electronic states of guanine rich DNA quadruplexes by quantum mechanical methods: main achievements and perspectives

The crystal structure of the superoxide dismutase from Helicobacter pylori reveals a structured C-terminal extension

The determinants of bond angle variability in protein/peptide backbones: A comprehensive statistical/quantum mechanics analysis.

The intrinsic stability of the human prion β-sheet region investigated by molecular dynamics

The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima

The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: hydration and sterochemical analysis