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List of works by Philip D Hodgkin

'Proliferative' and 'synthetic' airway smooth muscle cells are overlapping populations

scientific article

A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses

scientific article published on 7 November 2016

A cellular calculus for signal integration by T cells

scientific article (publication date: September 2000)

A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells

scientific article published in January 2003

A model for studying the hemostatic consumption or destruction of platelets

scientific article

A model of T cell-target interaction leading to lymphokine release

scientific article

A probabilistic view of immunology: drawing parallels with physics

scientific article published on 24 April 2007

A single-cell pedigree analysis of alternative stochastic lymphocyte fates.

scientific article

Absence of lipopolysaccharide high-dose paralysis in B-cell responses: Implications for the one-signal theory

article

Activation rules: the two-signal theories of immune activation

scientific article published in June 2002

Activation-induced B cell fates are selected by intracellular stochastic competition.

scientific article published on 5 January 2012

Affinity thresholds for naive CD8+ CTL activation by peptides and engineered influenza A viruses

scientific article

An analysis of tissue-specific transplantation phenomena in a minor histoincompatibility system

scientific article published on 01 June 1985

An antigen valence theory to explain the evolution and organization of the humoral immune response ⬇️

scientific article published on December 1, 1997

Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor-mediated functions.

scientific article published in May 1994

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

scientific article published in Science

Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow

scientific article published on 30 December 2003

Automatic generation of lymphocyte heterogeneity: Division-dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4+ T cells are independently regulated

scientific article published in February 2004

Autoreactive T cells in chronic spontaneous urticaria target the IgE Fc receptor Iα subunit

scientific article published on 8 June 2016

B cell differentiation induced by helper T cell membranes: evidence for sequential isotype switching and a requirement for lymphokines during proliferation

scientific article published in January 1994

B cell receptor-independent stimuli trigger immunoglobulin (Ig) class switch recombination and production of IgG autoantibodies by anergic self-reactive B cells.

scientific article

B cells activated via CD40 and IL-4 undergo a division burst but require continued stimulation to maintain division, survival and differentiation

scientific article published on 01 April 2001

B-Cell Activation by Helper T-Cell Membranes

scientific article

BAFF selectively enhances the survival of plasmablasts generated from human memory B cells

BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.

scientific article

Biological activity of recombinant murine interleukin-6 in interleukin-1 T cell assays

scientific article published on 01 June 1989

CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2

scientific article (publication date: June 2002)

Cell division number regulates IgG1 and IgE switching of B cells following stimulation by CD40 ligand and IL-4.

scientific article

Cell division regulates the T cell cytokine repertoire, revealing a mechanism underlying immune class regulation

scientific article

Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ

scientific article

Comparative evaluation of performance measures for shading correction in time-lapse fluorescence microscopy.

scientific article published on 21 December 2016

Concepts for the development of a quantitative theory of clonal selection and class regulation using lessons from the original

article

Converse Smith-Martin cell cycle kinetics by transformed B lymphocytes

scientific article published on 11 September 2018

Cross-Linking Surface Ig Delays CD40 Ligand- and IL-4-Induced B Cell Ig Class Switching and Reveals Evidence for Independent Regulation of B Cell Proliferation and Differentiation

article

Decision criteria for resolving isotype switching conflicts by B cells

scientific article published in October 2005

Delayed Diagnosis and Complications of Predominantly Antibody Deficiencies in a Cohort of Australian Adults.

scientific article published on 14 May 2018

Determining lineage pathways from cellular barcoding experiments

scientific article published on 6 February 2014

Determining the expected variability of immune responses using the cyton model

scientific article published on 3 November 2007

DiSNE Movie Visualization and Assessment of Clonal Kinetics Reveal Multiple Trajectories of Dendritic Cell Development.

scientific article published in March 2018

Divide and conquer: the importance of cell division in regulating B-cell responses.

scientific article published in August 2004

Division-linked differentiation can account for CD8+ T-cell phenotype in vivo

scientific article published in January 2009

Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development.

scientific article published on 23 May 2016

Early appearance of germinal center-derived memory B cells and plasma cells in blood after primary immunization.

scientific article

Estimating lymphocyte division and death rates from CFSE data

scientific article

Flow cytometric analysis of cell division history using dilution of carboxyfluorescein diacetate succinimidyl ester, a stably integrated fluorescent probe.

scientific article published in January 2001

Flow cytometric cell division tracking using nuclei

scientific article

Generation of splenic follicular structure and B cell movement in tumor necrosis factor-deficient mice.

scientific article

Genetic evidence for Lyn as a negative regulator of IL-4 signaling

article

Helper T cells: delivery of cell contact and lymphokine-dependent signals to B cells.

scientific article published on December 1993

High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency

scientific article published on 27 August 2012

High-affinity B cell receptor ligation by cognate antigen induces cytokine-independent isotype switching

scientific article published on 14 May 2010

IL-2, IL-6, and IFN-gamma have distinct effects on the IL-4 plus PMA-induced proliferation of thymocyte subpopulations

scientific article

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses.

scientific article

Identification of IL-6 as a T cell-derived factor that enhances the proliferative response of thymocytes to IL-4 and phorbol myristate acetate

scientific article published in July 1988

Immunophenotypic changes induced on human HL60 leukaemia cells by 1alpha,25-dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol-13-acetate

scientific article published on 17 March 2005

Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage

scientific article published in April 2005

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

scientific article published in May 2007

Interleukin-6. A multifunctional regulator of growth and differentiation.

scientific article published in January 1989

Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses

scientific article

Labour-efficient in vitro lymphocyte population tracking and fate prediction using automation and manual review.

scientific article

Life, death, and antibodies.

scientific article

Measuring lymphocyte proliferation, survival and differentiation using CFSE time-series data

scientific article

Mechanisms of cell division as regulators of acute immune response

scientific article

Membranes from both Th1 and Th2 T cell clones stimulate B cell proliferation and prepare B cells for lymphokine-induced differentiation to secrete Ig ⬇️

scientific article published on December 1, 1991

Modeling T- and B-cell growth and differentiation

scientific article

Modelling cell lifespan and proliferation: is likelihood to die or to divide independent of age?

scientific article published on December 2005

Modelling naive T-cell homeostasis: consequences of heritable cellular lifespan during ageing

scientific article published on 17 March 2009

Modifying clonal selection theory with a probabilistic cell.

scientific article published in September 2018

Multiplexed Division Tracking Dyes for Proliferation-Based Clonal Lineage Tracing

scientific article published on 18 June 2018

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals

scientific article published on January 2013

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells

scientific article published on 28 March 2016

Naive T cells are maintained by thymic output in early ages but by proliferation without phenotypic change after age twenty

scientific article published in December 2003

No luck replicating the immune response in twins

scientific article published on 25 March 2015

Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor alpha chain expression on activated B cells.

scientific article published on 4 February 2008

Platelet senescence is regulated by an internal timer, not damage inflicted by hits

scientific article published on 7 June 2010

Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses

scientific article

Quantitative regulation of B cell division destiny by signal strength

scientific article published in July 2008

Quantitative rules for lymphocyte regulation: the cellular calculus and decisions between tolerance and activation.

scientific article

Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation

scientific article

Regulation of lipopolysaccharide-induced B-cell activation: Evidence that surface immunoglobulin mediates two independently regulated signals

article

Regulation of platelet lifespan in the presence and absence of thrombopoietin signaling.

scientific article

Role of anti-donor antibody in the rejection of pig proislet xenografts in mice

scientific article published on 01 February 1998

Shedding light on cell cycle control by T and B lymphocytes

scientific article published on July 2015

Speculations on the evolution of humoral adaptive immunity

scientific article published on 05 March 2020

Stochastic Measurement Models for Quantifying Lymphocyte Responses Using Flow Cytometry

scientific article published on 7 January 2016

Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and Survival

scientific article published on 01 May 2003

Stretched cell cycle model for proliferating lymphocytes.

scientific article

Superior properties of CellTrace Yellow™ as a division tracking dye for human and murine lymphocytes.

scientific article published on 19 October 2017

Switch recombination and germ-line transcription are division-regulated events in B lymphocytes

scientific article published on 01 October 1999

Switching to IgG3, IgG2b, and IgA is division linked and independent, revealing a stochastic framework for describing differentiation

scientific article published on 01 November 1999

T-cell stimuli independently sum to regulate an inherited clonal division fate.

scientific article

TCR Affinity Promotes CD8+ T Cell Expansion by Regulating Survival

scientific article published on 01 August 2007

The BCL1 B lymphoma responds to IL-4, IL-5, and GM-CSF.

scientific article published in October 1989

The TNF Receptor Superfamily-NF-κB Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues

scientific article published on 4 September 2017

The clonal selection theory: 50 years since the revolution

scientific article

The cytotoxic response to murine cytomegalovirus. III. Lymphokine release and cytotoxicity are dependent upon phenotypically similar immune cell populations

scientific article published in December 1985

The effect of correlations on the population dynamics of lymphocytes

scientific article published on 19 February 2010

The effect of cyclosporin on major histocompatibility complex-linked resistance to murine cytomegalovirus.

scientific article published on May 1989

The generation of antibody-secreting plasma cells.

scientific article

The genetic network controlling plasma cell differentiation ⬇️

scientific article published on September 15, 2011

The golden anniversary of Burnet's clonal selection theory

scientific article published in January 2008

The importance of efficacy and partial agonism in evaluating models of B lymphocyte activation.

scientific article published on January 1997

The logic of intercellular communication in the immune system

scientific article published on 01 October 1998

The mechanism of T and B cell collaboration

scientific article published on April 1, 1992

The one signal theory of B cell activation revisited: A role for surface immunoglobulin in regulating T‐independent antibody responses? ⬇️

scientific article published on June 1, 1995

The proliferative response of CD4 T cells to steady-state CD8+ dendritic cells is restricted by post-activation death

scientific article

The regulation of lymphocyte activation and proliferation.

scientific article published on 2 February 2018

The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation

scientific article

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

scientific article published on 20 April 2015

Transcriptional repressor Blimp-1 is essential for T cell homeostasis and self-tolerance

scientific article published on 26 March 2006

Why does the thymus involute? A selection-based hypothesis.

scientific article

Why the immune system takes its chances with randomness

scientific article published on 12 September 2014

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