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List of works by Pippa J Tyrrell

A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

scientific article

A simple tool to identify elderly patients with a surgically important acute subdural haematoma.

scientific article published on 19 July 2014

A survey of the practice of stroke doctors in developing transient ischaemic attack services in the UK.

scientific article published on June 2007

Accuracy and clinical usefulness of intracerebral hemorrhage grading scores: a direct comparison in a UK population.

scientific article published on 16 May 2013

Acute stroke following cisplatin therapy

scientific article

Adjunctive functional pharyngeal electrical stimulation reverses swallowing disability after brain lesions

scientific article published on 2 February 2010

An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis

scientific article published in June 2003

Apraxia of gait or higher level gait disorders: review and description of two cases of progressive gait disturbance due to frontal lobe degeneration

article

Association of age with regional cerebral oxygen utilization: a positron emission tomography study

scientific article published in September 1992

Associations between stroke mortality and weekend working by stroke specialist physicians and registered nurses: prospective multicentre cohort study

scientific article

Associations between the organisation of stroke services, process of care, and mortality in England: prospective cohort study

scientific article published on 10 May 2013

Authors' reply to Hill and Rudd

scientific article published on 23 September 2014

Awareness of dysphagia by patients following stroke predicts swallowing performance

scientific article

Brain inflammation is induced by co-morbidities and risk factors for stroke

scientific article

Can a novel clinical risk score improve pneumonia prediction in acute stroke care? A UK multicenter cohort study

scientific article

Care-limiting decisions in acute stroke and association with survival: analyses of UK national quality register data.

scientific article

Cerebral mechanisms operating in the presence and absence of inflammatory pain

scientific article

Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection.

scientific article

Clarification of conclusions from the ACT NoW trial

scientific article published on 08 January 2013

Classification of Minor Stroke: Intra- and Inter-Observer Reliability

scientific article published on 29 January 2009

Clinical and positron emission tomographic studies in the 'extrapyramidal syndrome' of dementia of the Alzheimer type.

scientific article

Clinical effectiveness, cost-effectiveness and service users' perceptions of early, well-resourced communication therapy following a stroke: a randomised controlled trial (the ACT NoW Study).

scientific article published in May 2012

Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production

scientific article

Correlation of systemic inflammatory response with infarct volume in acute ischemic stroke patients

scientific article published on 29 December 2004

Current and emerging treatments for acute stroke: relationships with infection

scientific article published on April 2010

Deglutitive laryngeal closure in stroke patients

scientific article

Dementia with Lewy bodies studied with positron emission tomography

scientific article published in March 2001

Derivation and external validation of a case mix model for the standardized reporting of 30-day stroke mortality rates

scientific article published on 7 October 2014

Developing functional outcome measures for unilateral neglect: a pilot study

scientific article published in May 2005

Development and feasibility testing of an oral hygiene intervention for stroke unit care. ⬇️

scientific article published on 16 May 2016

Diagnosis and initial management of acute stroke and transient ischaemic attack: summary of NICE guidance

scientific article published on 24 July 2008

Diagnosis and initial management of transient ischaemic attack.

scientific article published in April 2010

Diagnosis of Stroke-Associated Pneumonia: Recommendations From the Pneumonia in Stroke Consensus Group

scientific article

Difficulties with recruiting into neurosurgical clinical trials: The Surgical Trial in IntraCerebral Haemorrhage II as an example

scientific article published on 23 February 2011

Does inflammation predispose to recurrent vascular events after recent transient ischaemic attack and minor stroke? The North West of England transient ischaemic attack and minor stroke (NORTHSTAR) study

scientific article (publication date: June 2011)

EXTRAPYRAMIDAL SIGNS IN DEMENTIA OF ALZHEIMER TYPE

scientific article published in The Lancet

Effect of central cholinergic stimulation on regional cerebral blood flow in Alzheimer's disease

scientific article published in April 1991

Effectiveness of enhanced communication therapy in the first four months after stroke for aphasia and dysarthria: a randomised controlled trial

scientific article

Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial

scientific article

Effects of Centralizing Acute Stroke Services on Stroke Care Provision in Two Large Metropolitan Areas in England

scientific article published on 30 June 2015

Evaluating oral stimulation as a treatment for dysphagia after stroke

scientific article published in January 2006

Evaluation of a service development to implement the top three process indicators for quality stroke care

scientific article (publication date: February 2007)

Evaluation of reconfigurations of acute stroke services in different regions of England and lessons for implementation: a mixed-methods study

Example of a health divide?

scientific article published in the British Medical Journal

Explaining outcomes in major system change: a qualitative study of implementing centralised acute stroke services in two large metropolitan regions in England

scientific article

Feasibility of assessing the needs of stroke patients after six months using the GM-SAT.

scientific article published on 5 September 2012

Heterogeneity in progressive aphasia due to focal cortical atrophy. A clinical and PET study

scientific article published in October 1990

How is pneumonia diagnosed in clinical stroke research? A systematic review and meta-analysis.

scientific article published on 09 April 2015

Imaging in young adults with intracerebral hemorrhage

scientific article published on 21 April 2012

Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis

scientific article

Impact of specialist neurovascular care in subarachnoid haemorrhage

scientific article published on 16 March 2015

Improving care for people after stroke: how change was actively facilitated

scientific article published on January 2013

Incidence, predictors and clinical characteristics of orolingual angio-oedema complicating thrombolysis with tissue plasminogen activator for ischaemic stroke

scientific article published on 12 July 2014

Inflammation and infection in clinical stroke

scientific article (publication date: December 2002)

Inflammation and ischaemic stroke.

scientific article published on June 2007

Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage

scientific article published on 05 September 2012

Inflammation in acute ischemic stroke and its relevance to stroke critical care.

scientific article published on January 2008

Innovations in major system reconfiguration in England: a study of the effectiveness, acceptability and processes of implementation of two models of stroke care

scientific article published on 5 January 2013

Interleukin-1 and neuronal injury

scientific article

Interleukin-1 in Stroke: From Bench to Bedside

scientific article

Interleukin-1 receptor antagonist in animal models of stroke: a fair summing up?

scientific article published on 10 July 2010

Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations

scientific article

Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression

scientific article published on 22 March 2012

Interleukin-6 and acute ischaemic stroke.

scientific article published in October 2005

Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study

scientific article

Investigation of the opioid system in absence seizures with positron emission tomography.

scientific article

Long-term temperature-related morbidity after brain damage: Survivor-reported experiences

scientific article published on 01 July 2008

MATTERS ARISING: Rossor and Tyrrell reply;.

scientific article published in November 1992

Managing stroke and transient ischaemic attacks.

scientific article

Measuring stroke care and quality in routine data sets

scientific article

NICE guideline on acute stroke and TIA: commentary

scientific article published on 01 May 2009

Organisation, practice and experiences of mouth hygiene in stroke unit care: a mixed-methods study

scientific article

Patient-directed therapy during in-patient stroke rehabilitation: stroke survivors' views of feasibility and acceptability.

scientific article published on 28 April 2015

Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome

scientific article

Peripheral inflammatory markers in amnestic mild cognitive impairment

scientific article

Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage

scientific article published on 13 September 2007

Phase II Pragmatic Randomized Controlled Trial of Patient-Led Therapies (Mirror Therapy and Lower-Limb Exercises) During Inpatient Stroke Rehabilitation

scientific article

Phase II anti-inflammatory and immune-modulating drugs for acute ischaemic stroke

scientific article

Post stroke shoulder pain: more common than previously realized

scientific article published in January 2000

Poststroke shoulder pain: a prospective study of the association and risk factors in 152 patients from a consecutive cohort of 205 patients presenting with stroke

scientific article

Potential surrogate markers of cerebral microvascular angiopathy in asymptomatic subjects at risk of stroke

scientific article

Predicting aspiration after hemispheric stroke from timing measures of oropharyngeal bolus flow and laryngeal closure

scientific article published on 28 February 2009

Prognosis in patients with transient ischaemic attack (TIA) and minor stroke attending TIA services in the North West of England: the NORTHSTAR Study.

scientific article published on 22 November 2007

Progressive frontal gait disturbance with atypical Alzheimer's disease and corticobasal degeneration

scientific article

Psychiatric symptoms in patients with focal cortical degeneration

scientific article published on 01 January 1994

Rapid assessment vital in stroke and TIA

scientific article published on 01 November 2008

Rapid brain penetration of interleukin-1 receptor antagonist in rat cerebral ischaemia: pharmacokinetics, distribution, protection

scientific article published on May 2010

Rapid diagnosis of TIA reduces risk of subsequent stroke.

scientific article published on September 2012

Recruiting to inpatient-based rehabilitation trials: lessons learned.

scientific article

Regulation of interleukin-1 in acute brain injury ⬇️

scientific article published on July 23, 2011

Reliability of a semi-automated technique of cerebral infarct volume measurement with CT.

scientific article

Reply to Comment on 'Pitfalls in microdialysis methodology: an in vitro analysis of temperature, pressure and catheter use'.

scientific article published in March 2015

Sciatic nerve damage due to toilet seat entrapment: another Saturday night palsy

scientific article

Short-term effects of ambient particulates and gaseous pollutants on the incidence of transient ischaemic attack and minor stroke: a case-crossover study

scientific article

Shoulder pain after stroke: case report and review

scientific article published in July 1999

Stroke thrombolysis in England: an age stratified analysis of practice and outcome

scientific article published on 22 November 2012

Study design and population pharmacokinetic analysis of a phase II dose-ranging study of interleukin-1 receptor antagonist

scientific article

The Nottingham Fatigue After Stroke (NotFAST) study: results from follow-up six months after stroke.

scientific article

The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography.

scientific article published in September 2001

The association between delays in screening for and assessing dysphagia after acute stroke, and the risk of stroke-associated pneumonia

scientific article published on 13 June 2016

The association of gegenhalten in the upper limbs with dyspraxia

scientific article

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

scientific article

The importance of angiographic and venographic cranial imaging in intracerebral hemorrhage occurring during pregnancy and the puerperium

scientific article published on 01 September 2011

The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease

scientific article published in December 1990

The study protocol of: 'Initiating end of life care in stroke: clinical decision-making around prognosis'. ⬇️

scientific article

The timing, extent, progression and regression of deep vein thrombosis in immobile stroke patients: observational data from the CLOTS multicenter randomized trials

scientific article

The unreliability of clinical measures of muscle tone: implications for stroke therapy

scientific article published in May 2000

Variability of the systemic acute phase response after ischemic stroke

scientific article published on 7 November 2006

Weekly variation in health-care quality by day and time of admission: a nationwide, registry-based, prospective cohort study of acute stroke care

scientific article

What is rehabilitation potential? Development of a theoretical model through the accounts of healthcare professionals working in stroke rehabilitation services ⬇️

scientific article published on 12 December 2014

Why do patients with stroke not receive the recommended amount of active therapy (ReAcT)? Study protocol for a multisite case study investigation ⬇️

scientific article

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