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List of works by Pippa J Tyrrell

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The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

scientific article
Interleukin-1 and neuronal injury

scientific article
A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

scientific article
Peak plasma interleukin-6 and other peripheral markers of inflammation in the first week of ischaemic stroke correlate with brain infarct volume, stroke severity and long-term outcome

scientific article
The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease

scientific article published in December 1990
An early and sustained peripheral inflammatory response in acute ischaemic stroke: relationships with infection and atherosclerosis

scientific article published in June 2003
Inflammation and infection in clinical stroke

scientific article (publication date: December 2002)
Inflammation and ischaemic stroke.

scientific article published on June 2007
Brain inflammation is induced by co-morbidities and risk factors for stroke

scientific article
Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial

scientific article
Impact of centralising acute stroke services in English metropolitan areas on mortality and length of hospital stay: difference-in-differences analysis

scientific article
Heterogeneity in progressive aphasia due to focal cortical atrophy. A clinical and PET study

scientific article published in October 1990
Diagnosis of Stroke-Associated Pneumonia: Recommendations From the Pneumonia in Stroke Consensus Group

scientific article
Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations

scientific article
Intravenous anakinra can achieve experimentally effective concentrations in the central nervous system within a therapeutic time window: results of a dose-ranging study

scientific article
Adjunctive functional pharyngeal electrical stimulation reverses swallowing disability after brain lesions

scientific article published on 2 February 2010
Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage

scientific article published on 05 September 2012
Poststroke shoulder pain: a prospective study of the association and risk factors in 152 patients from a consecutive cohort of 205 patients presenting with stroke

scientific article
Deglutitive laryngeal closure in stroke patients

scientific article
Weekly variation in health-care quality by day and time of admission: a nationwide, registry-based, prospective cohort study of acute stroke care

scientific article
Rapid brain penetration of interleukin-1 receptor antagonist in rat cerebral ischaemia: pharmacokinetics, distribution, protection

scientific article published on May 2010
Associations between stroke mortality and weekend working by stroke specialist physicians and registered nurses: prospective multicentre cohort study

scientific article
Effectiveness of enhanced communication therapy in the first four months after stroke for aphasia and dysarthria: a randomised controlled trial

scientific article
Associations between the organisation of stroke services, process of care, and mortality in England: prospective cohort study

scientific article published on 10 May 2013
Regulation of interleukin-1 in acute brain injury

scientific article published on July 23, 2011
Inflammation in acute ischemic stroke and its relevance to stroke critical care.

scientific article published on January 2008
Diagnosis and initial management of acute stroke and transient ischaemic attack: summary of NICE guidance

scientific article published on 24 July 2008
Awareness of dysphagia by patients following stroke predicts swallowing performance

scientific article
Predicting aspiration after hemispheric stroke from timing measures of oropharyngeal bolus flow and laryngeal closure

scientific article published on 28 February 2009
Clinical outcome following acute ischaemic stroke relates to both activation and autoregulatory inhibition of cytokine production

scientific article published on 28 February 2007
Interleukin-1 receptor antagonist reverses stroke-associated peripheral immune suppression

scientific article published on 22 March 2012
Cerebrospinal fluid and plasma cytokines after subarachnoid haemorrhage: CSF interleukin-6 may be an early marker of infection.

scientific article
How is pneumonia diagnosed in clinical stroke research? A systematic review and meta-analysis.

scientific article published on 09 April 2015
Accuracy and clinical usefulness of intracerebral hemorrhage grading scores: a direct comparison in a UK population.

scientific article published on 16 May 2013
Pharmacokinetic modelling of interleukin-1 receptor antagonist in plasma and cerebrospinal fluid of patients following subarachnoid haemorrhage

scientific article published on 13 September 2007
Clinical effectiveness, cost-effectiveness and service users' perceptions of early, well-resourced communication therapy following a stroke: a randomised controlled trial (the ACT NoW Study).

scientific article published in May 2012
Effects of Centralizing Acute Stroke Services on Stroke Care Provision in Two Large Metropolitan Areas in England

scientific article published on 30 June 2015
Evaluating oral stimulation as a treatment for dysphagia after stroke

scientific article published in January 2006
Can a novel clinical risk score improve pneumonia prediction in acute stroke care? A UK multicenter cohort study

scientific article
Variability of the systemic acute phase response after ischemic stroke

scientific article published on 7 November 2006
Clinical and positron emission tomographic studies in the 'extrapyramidal syndrome' of dementia of the Alzheimer type.

scientific article
Interleukin-1 in Stroke: From Bench to Bedside

scientific article
Investigation of the opioid system in absence seizures with positron emission tomography.

scientific article
The association between delays in screening for and assessing dysphagia after acute stroke, and the risk of stroke-associated pneumonia

scientific article published on 13 June 2016
Prognosis in patients with transient ischaemic attack (TIA) and minor stroke attending TIA services in the North West of England: the NORTHSTAR Study.

scientific article published on 22 November 2007
Explaining outcomes in major system change: a qualitative study of implementing centralised acute stroke services in two large metropolitan regions in England

scientific article
Innovations in major system reconfiguration in England: a study of the effectiveness, acceptability and processes of implementation of two models of stroke care

scientific article published on 5 January 2013
Progressive frontal gait disturbance with atypical Alzheimer's disease and corticobasal degeneration

scientific article
Phase II anti-inflammatory and immune-modulating drugs for acute ischaemic stroke

scientific article
Post stroke shoulder pain: more common than previously realized

scientific article published in January 2000

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