Search filters

List of works by Xiaokui Huo

A natural inhibitor from Alisma orientale against human carboxylesterase 2: Kinetics, circular dichroism spectroscopic analysis, and docking simulation

scientific article published on 13 April 2019

Alisma genus: Phytochemical constituents, biosynthesis, and biological activities

scientific article published on 13 November 2020

Alisol B 23-acetate protects against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes involved in bile acid homeostasis

scientific article published on 3 February 2015

Alisol B 23-acetate protects against non-alcoholic steatohepatitis in mice via farnesoid X receptor activation.

scientific article published on 24 October 2016

Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat

scientific article published on 01 April 2014

Bezafibrate-mizoribine interaction: Involvement of organic anion transporters OAT1 and OAT3 in rats

scientific article published on 13 October 2015

Bioactive metabolites of Schisanlactone E transformed by Cunninghamella blakesleana AS 3.970.

scientific article published on 30 October 2014

Biotransformation of 11-keto-β-boswellic acid by Cunninghamella blakesleana.

scientific article published on 17 August 2013

Biotransformation of furanocoumarins by fungi: preparation of imperation analogs.

scientific article published on 31 January 2017

Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor

scientific article published on 13 December 2016

Characterization of phase I metabolism of resibufogenin and evaluation of the metabolic effects on its antitumor activity and toxicity

scientific article published on 11 December 2014

Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

scientific article published on 18 February 2019

Decreased liver distribution of entecavir is related to down-regulation of Oat2/Oct1 and up-regulation of Mrp1/2/3/5 in rat liver fibrosis.

scientific article

Demethylbellidifolin isolated from Swertia bimaculate against human carboxylesterase 2: Kinetics and interaction mechanism merged with docking simulations

scientific article published on 03 July 2019

Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo

scientific journal article

Dioscin protects against ANIT-induced cholestasis via regulating Oatps, Mrp2 and Bsep expression in rats.

scientific article published on 14 June 2016

Dioscin restores the activity of the anticancer agent adriamycin in multidrug-resistant human leukemia K562/adriamycin cells by down-regulating MDR1 via a mechanism involving NF-κB signaling inhibition

scientific article published on 26 April 2013

Dioscin strengthens the efficiency of adriamycin in MCF-7 and MCF-7/ADR cells through autophagy induction: More than just down-regulation of MDR1.

scientific article

Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction

scientific article published on 18 May 2016

Effect of Alkaloids Isolated from Phyllodium pulchellum on Monoamine Levels and Monoamine Oxidase Activity in Rat Brain.

scientific article published on 18 April 2016

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin

scientific article

Enhancement effect of resveratrol on the intestinal absorption of bestatin by regulating PEPT1, MDR1 and MRP2 in vivo and in vitro.

scientific article published on 19 September 2015

Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells.

scientific article published on 15 February 2016

Gamabufotalin, a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells.

scientific article

Gamabufotalin, a major derivative of bufadienolide, inhibits VEGF-induced angiogenesis by suppressing VEGFR-2 signaling pathway.

scientific article published on 9 December 2015

Highly potent non-steroidal FXR agonists protostane-type triterpenoids: Structure-activity relationship and mechanism

scientific article published on 28 August 2019

Human transporters, PEPT1/2, facilitate melatonin transportation into mitochondria of cancer cells: An implication of the therapeutic potential

scientific article published on 18 January 2017

Identification of the hydroxylated derivatives of bufalin: phase I metabolites in rats.

scientific article published on 17 November 2015

Identifying and applying a highly selective probe to simultaneously determine the O-glucuronidation activity of human UGT1A3 and UGT1A4.

scientific article

Inhibition of melatonin metabolism in humans induced by chemical components from herbs and effective prediction of this risk using a computational model

scientific article published on 2 September 2016

Inhibitory Effects of Highly Oxygenated Lanostane Derivatives from the Fungus Ganoderma lucidum on P-Glycoprotein and α-Glucosidase

scientific article published on 29 July 2015

Inhibitory effect of valsartan on the intestinal absorption and renal excretion of bestatin in rats

scientific article published on 11 December 2013

Involvement of organic anion-transporting polypeptides in the hepatic uptake of dioscin in rats and humans

scientific article published on 8 February 2013

Liver-targeting Resibufogenin-loaded poly(lactic-co-glycolic acid)-D-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles for liver cancer therapy.

scientific article published on 27 January 2016

MDR1 and OAT1/OAT3 mediate the drug-drug interaction between puerarin and methotrexate.

scientific article published on 16 November 2013

Metabolic Profile of 3-Acetyl-11-Keto-β-Boswellic Acid and 11-Keto-β-Boswellic Acid in Human Preparations In Vitro, Species Differences, and Bioactivity Variation

scientific article published on 21 June 2016

Methotrexate-bestatin interaction: involvement of P-glycoprotein and organic anion transporters in rats

scientific article published on 13 February 2014

Microbial transformation of resibufogenin by Curvularia lunata AS 3.4381

scientific article published on 01 January 2014

OATP and MRP2-mediated hepatic uptake and biliary excretion of eprosartan in rat and human.

scientific article published on 10 March 2014

Organic anion transporter 3 (OAT3)-mediated transport of dicaffeoylquinic acids and prediction of potential drug-drug interaction

scientific article published on 27 March 2019

Oxidative coupling of coumarins catalyzed by laccase

scientific article published on 01 June 2019

P-gp, MRP2 and OAT1/OAT3 mediate the drug-drug interaction between resveratrol and methotrexate

scientific article published in July 2016

PEPT1- and OAT1/3-mediated drug-drug interactions between bestatin and cefixime in vivo and in vitro in rats, and in vitro in human

scientific article published on 09 July 2014

Phenolic constituents from the roots of Phyllodium pulchellum

scientific article published on 23 April 2014

Phytochemical constituents from Uncaria rhynchophylla in human carboxylesterase 2 inhibition: Kinetics and interaction mechanism merged with docking simulations

scientific article published on 10 October 2018

Protective Effects of Alisol B 23-Acetate Via Farnesoid X Receptor-Mediated Regulation of Transporters and Enzymes in Estrogen-Induced Cholestatic Liver Injury in Mice.

scientific article published on 4 June 2015

Protective effect of cilastatin against diclofenac-induced nephrotoxicity through interaction with diclofenac acyl glucuronide via organic anion transporters

scientific article published on 30 January 2020

Protective effects of alisol B 23-acetate from edible botanical Rhizoma alismatis against carbon tetrachloride-induced hepatotoxicity in mice.

scientific article published in April 2015

Protective effects of calycosin against CCl4-induced liver injury with activation of FXR and STAT3 in mice

scientific article published on 21 August 2014

Puerarin sensitized K562/ADR cells by inhibiting NF-κB pathway and inducing autophagy

scientific article published on 03 November 2020

Quantitative proteomics reveals molecular mechanism of gamabufotalin and its potential inhibition on Hsp90 in lung cancer

scientific article published on 02 July 2016

Simultaneous determination of three dipeptides (JBP485, Gly-Sar and JBP923) in the cell lysates by liquid chromatography-tandem mass spectrometry: application to identify the function of the PEPT1 transfected cell.

scientific article

Sulfation of melatonin: enzymatic characterization, differences of organs, species and genders, and bioactivity variation.

scientific article

Targeting Oct2 and P53: Formononetin prevents cisplatin-induced acute kidney injury.

scientific article

Targeting P-glycoprotein expression and cancer cell energy metabolism: combination of metformin and 2-deoxyglucose reverses the multidrug resistance of K562/Dox cells to doxorubicin

scientific article published on 6 January 2016

Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin

scientific article published on 30 December 2016

Targeting renal OATs to develop renal protective agent from traditional Chinese medicines: Protective effect of Apigenin against Imipenem-induced nephrotoxicity

scientific article published on 28 May 2020

The natural anthraquinones from Rheum palmatum induced the metabolic disorder of melatonin by inhibiting human CYP and SULT enzymes

scientific article published on 12 September 2016

[Chemical constituents against hepatic fibrosis from Phyllodium pulchellum roots]

scientific article published on 01 March 2014

β-Glucuronidase- and OATP2B1-mediated drug interaction of scutellarin in Dengzhan Xixin Injection: A formulation aspect

scientific article published on 27 March 2020

Paulina is supported by:

About Paulina

Help