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List of works by Fujie Tanaka

1,1'-Binaphthalene-2,2'-diol as a Chiral Auxiliary. Diastereoselective Alkylation of Binaphthyl Esters, Complex-Induced Proximity Effects in Enolate Formation, and One-Step Synthesis of an Optically Active .beta.-Substituted Ketone

article published in 1995

3-Pyrrolidinecarboxylic acid for direct catalytic asymmetric anti-Mannich-type reactions of unmodified ketones

scientific article

7 Catalytic antibodies

article published in 2005

A Way to Highly Enantiomerically Enriched aza-Morita–Baylis–Hillman–Type Products

A Way to Highly Enantiomerically Enriched aza-Morita–Baylis–Hillman–Type Products

scholarly article by Naoto Utsumi et al published 5 March 2007 in Angewandte Chemie International Edition

A common ancestry for multiple catalytic antibodies generated against a single transition-state analog.

scientific article published on June 1994

A fluorogenic aldehyde bearing a 1,2,3-triazole moiety for monitoring the progress of aldol reactions

scientific article published in March 2009

A highly enantioselective route to either enantiomer of both alpha- and beta-amino acid derivatives

scientific article

A lipid-coated catalytic antibody in water-miscible organic solvents

article

A modular assembly strategy for improving the substrate specificity of small catalytic peptides

scientific article

A structural basis for transition-state stabilization in antibody-catalyzed hydrolysis: crystal structures of an abzyme at 1. 8 A resolution

scientific article published in August 1998

Aldol Reactions of Ketone Donors with Aryl Trifluoromethyl Ketone Acceptors Catalyzed by 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) for Concise Access to Aryl- and Trifluoromethyl- Substituted Tertiary Alcohols

article

Aldol reactions of 1,2-diketones catalyzed by amines to afford furanose derivatives

Aldolase antibody activation of prodrugs of potent aldehyde-containing cytotoxics for selective chemotherapy

scientific article published on October 2004

Amine-catalyzed Michael reactions of an aminoaldehyde derivative to nitroolefins

Amine-catalyzed direct Diels–Alder reactions of α,β-unsaturated ketones with nitro olefins

Anti-formyl peptide antibodies

scientific article published in 2007

Antibody-catalyzed Aldol Reactions

Antibody-catalyzed aminolysis of a chloropyrimidine derivative

scientific article

Binaphthol as a chiral auxiliary. Asymmetrical alkylation of arylacetic acid

article published in 1989

Binaphthol as a chiral auxilliary: diastereoselective alkylation of binaphthyl esters of α,β-unsaturated carboxylic acids

C-Glycosidation of Unprotected Di- and Trisaccharide Aldopyranoses with Ketones Using Pyrrolidine-Boric Acid Catalysis

Catalysis of 3-pyrrolidinecarboxylic acid and related pyrrolidine derivatives in enantioselective anti-Mannich-type reactions: importance of the 3-acid group on pyrrolidine for stereocontrol

scientific article published on 29 December 2007

Catalytic Direct Asymmetric Michael Reactions: Addition of Unmodified Ketone and Aldehyde Donors to Alkylidene Malonates and Nitro Olefins

article

Catalytic Enantioselective Formal (4+2) Cycloaddition by Aldol-Aldol Annulation of Pyruvate Derivatives with Cyclohexane-1,3-Diones to Afford Functionalized Decalins

Catalytic Enantioselective Formal (4+2) Cycloaddition by Aldol-Aldol Annulation of Pyruvate Derivatives with Cyclohexane-1,3-Diones to Afford Functionalized Decalins

scientific article published on 07 September 2018

Catalytic Enantioselective Formal Hetero-Diels-Alder Reactions of Enones with Isatins to Give Spirooxindole Tetrahydropyranones

Catalytic antibodies as designer proteases and esterases

scientific article

Catalytic asymmetric hetero-Diels–Alder reactions of enones with isatins to access functionalized spirooxindole tetrahydropyrans: scope, derivatization, and discovery of bioactives

article published in 2016

Catalytic single-chain antibodies possessing β-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor

Complex-induced proximity effects in enolate formation. Highly diastereoselective α-methylation of binaphthyl esters of arylacetic acids

article published in 1990

Control of Chemical Reactions by Using Molecules that Buffer Non-aqueous Solutions

scientific article published on 19 November 2019

Control of function of a small peptide by a protein

scientific article

Correction: Synthesis of pyrrolidine-3-carboxylic acid derivatives via asymmetric Michael addition reactions of carboxylate-substituted enones

article

Correlation between Antigen-Combining-Site Structures and Functions within a Panel of Catalytic Antibodies Generated against a Single Transition State Analog

scientific article published in 1995

Corrigendum: Catalytic Enantioselective Formal Hetero-Diels-Alder Reactions of Enones with Isatins to Give Spirooxindole Tetrahydropyranones

scholarly article published in Chemistry—A European Journal

Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede

scientific article

De novo computational design of retro-aldol enzymes

scientific article

Design and use of fluorogenic aldehydes for monitoring the progress of aldehyde transformations

scientific article published in March 2004

Detection of enantiomers of chiral primary amines by 1 H NMR analysis via enamine formation with an enantiopure γ-position aldol product of a β-keto ester

Determination of Relative Frequency of Carbanion Formation at α-Positions of Ketones under Aldol Reaction Catalysis Conditions.

scientific article published on 3 July 2017

Determination of cysteine concentration by fluorescence increase: reaction of cysteine with a fluorogenic aldehyde

scientific article

Development of a small peptide tag for covalent labeling of proteins

scientific article

Development of protein, peptide, and small molecule catalysts using catalysis-based selection strategies

scientific article published in January 2005

Development of small designer aldolase enzymes: catalytic activity, folding, and substrate specificity

scientific article

Dihydroxyacetone variants in the organocatalytic construction of carbohydrates: mimicking tagatose and fuculose aldolases

scientific article published in May 2006

Direct Asymmetric Organocatalytic Michael Reactions of α,α-Disubstituted Aldehydes with β-Nitrostyrenes for the Synthesis of Quaternary Carbon-Containing Products

scientific article published in 2004

Direct Catalytic Asymmetric Synthesis of Oxindole-Derived δ-Hydroxy-β-ketoesters by Aldol Reactions

scientific article published on 20 November 2019

Direct Observation of an Enamine Intermediate in Amine Catalysis

scientific article

Direct Organocatalytic Asymmetric Aldol Reactions of α-Amino Aldehydes:  Expedient Syntheses of Highly Enantiomerically Enrichedanti-β-Hydroxy-α-amino Acids

scientific article published in 2004

Direct asymmetric anti-Mannich-type reactions catalyzed by a designed amino acid

scientific article

Direct catalytic asymmetric synthesis of anti-1,2-amino alcohols and syn-1,2-diols through organocatalytic anti-Mannich and syn-aldol reactions

scientific article published in January 2007

Direct synthesis of C-glycosides from unprotected 2-N-acyl-aldohexoses via aldol condensation–oxa-Michael reactions with unactivated ketones

Discovery of SOAT2 inhibitors from synthetic small molecules.

scientific article published on 5 November 2016

Enamine Catalysis: Aldol and Mannich-Type Reactions

Enamine-Based Reactions: Strategies for the Development of Organocatalysts and Catalyzed Reactions

article

Enamine-based Reactions Using Organocatalysts: from Aldolase Antibodies to Small Amino Acid and Amine Catalysts

Enamine-based organocatalysis with proline and diamines: the development of direct catalytic asymmetric Aldol, Mannich, Michael, and Diels-alder reactions

scientific article

Enantioselective Direct anti-Selective Mannich-type Reactions Catalyzed by 3-Pyrrolidinecarboxylic Acid in the Presence of Potassium Carbonate: Addition of Potassium Carbonate Improves Enantioselectivities

scientific article published on 19 May 2020

Erratum to “Fluorogenic probes for chemical transformations: 9-anthracene derivatives for monitoring reaction progress by an increase in fluorescence” [Tetrahedron Lett. 54 (2013) 4306–4308]

scholarly article published in Tetrahedron Letters

Evolution of aldolase antibodies in vitro: correlation of catalytic activity and reaction-based selection

scientific article

Expedient Synthesis of Chiral 1,2- and 1,4-Diamines:  Protecting Group Dependent Regioselectivity in Direct Organocatalytic Asymmetric Mannich Reactions

article published in 2006

Fluorescent detection of carbon-carbon bond formation

scientific article published in July 2003

Fluorogenic aldehydes bearing arylethynyl groups: turn-on aldol reaction sensors for evaluation of organocatalysis in DMSO

Fluorogenic imines for fluorescent detection of Mannich-type reactions of phenols in water

scientific article published on 23 April 2008

Fluorogenic probes for aldol reactions: tuning of fluorescence using π-conjugation systems

Fluorogenic probes for chemical transformations: 9-anthracene derivatives for monitoring reaction progress by an increase in fluorescence

article published in 2013

Formal (4+1) Cycloaddition and Enantioselective Michael-Henry Cascade Reactions To Synthesize Spiro[4,5]decanes and Spirooxindole Polycycles

scientific article

Formal (4+1) Cycloaddition and Enantioselective Michael-Henry Cascade Reactions To Synthesize Spiro[4,5]decanes and Spirooxindole Polycycles

Imines that react with phenols in water over a wide pH range

scientific article published on 10 October 2008

Inside Cover: Reaction-Based Mechanistic Investigations of Asymmetric Hetero-Diels-Alder Reactions of Enones with Isatins Catalyzed by Amine-Based Three-Component Catalyst Systems (Asian J. Org. Chem. 1/2016)

article

Intramolecular Mannich and Michael Annulation Reactions of Lactam Derivatives Bearing Enals To Afford Bicyclic N-Heterocycles

scientific article published on 04 October 2019

Mannich Reactions of Carbohydrate Derivatives with Ketones To Afford Polyoxy-Functionalized Piperidines

scientific article published on 29 January 2019

Mimicking Aldolases through Organocatalysis: syn-Selective Aldol Reactions with Protected Dihydroxyacetone

scientific article published in 2007

Mimicking Fructose and Rhamnulose Aldolases: Organocatalyticsyn-Aldol Reactions with Unprotected Dihydroxyacetone

Mimicking fructose and rhamnulose aldolases: organocatalytic syn-aldol reactions with unprotected dihydroxyacetone

scientific article published in January 2007

One-Pot Asymmetric Synthesis of β-Cyanohydroxymethyl α-Amino Acid Derivatives:  Formation of Three Contiguous Stereogenic Centers

scientific article published on 01 December 2002

One-pot synthesis of polysubstituted 3-acylpyrroles by cooperative catalysis

Organocatalytic Direct Michael Reaction of Ketones and Aldehydes with β-Nitrostyrene in Brine [J. Am. Chem. Soc.2006,128, 4966−4967]

scientific article published in 2006

Organocatalytic direct asymmetric aldol reactions in water

scientific article

Organocatalytic direct michael reaction of ketones and aldehydes with beta-nitrostyrene in brine

scientific article

Organocatalyticanti-Mannich Reactions with Dihydroxyacetone and Acyclic Dihydroxyacetone Derivatives: A Facile Route to Amino Sugars

scholarly article by Haile Zhang et al published 7 April 2008 in Advanced Synthesis & Catalysis

Phage display selection of peptides possessing aldolase activity

article published in 2001

Pipecolic acid-catalyzed direct asymmetric mannich reactions

scientific article

Pyridoxal-mediated abzyme system for aldol and retro-aldol reactions

Rapid Fluorescent Screening for Bifunctional Amine−Acid Catalysts:  Efficient Syntheses of Quaternary Carbon-Containing Aldols under Organocatalysis

article published in 2003

Rapid analysis of solvent effects on enamine formation by fluorescence: how might enzymes facilitate enamine chemistry with primary amines?

Reaction-Based Mechanistic Investigations of Asymmetric Hetero-Diels-Alder Reactions of Enones with Isatins Catalyzed by Amine-Based Three-Component Catalyst Systems

Reactions of pyruvates: organocatalytic synthesis of functionalized dihydropyrans in one pot and further transformations to functionalized carbocycles and heterocycles

Reactive Immunization: A Unique Approach to Aldolase Antibodies

Reactive immunization: a unique approach to catalytic antibodies

scientific article

Reconstructing Aldolase Antibodies to Alter Their Substrate Specificity and Turnover

article published in 2000

Relaxing Substrate Specificity in Antibody-Catalyzed Reactions: Enantioselective Hydrolysis ofN-Cbz-Amino Acid Esters

scientific article published in 1996

Selection of phage-displayed peptides that bind to a particular ligand-bound antibody

scientific article

Stereochemistry of the enolate from methyl phenylacetate

article published in 1992

Substituent-dependent reactivity in aldehyde transformations: 4-(phenylethynyl)benzaldehydes versus simple benzaldehydes

Switching Electrophile Intermediates to Nucleophiles: Michael and Oxa-Diels-Alder Reactions to Afford Polyoxy-Functionalized Piperidine Derivatives with Tetrasubstituted Carbon

scientific article published on 20 March 2020

Synthesis and evaluation of a cyclic imine derivative conjugated to a fluorescent molecule for labeling of proteins

scientific article published on 25 December 2008

Synthesis of Furanose Spirooxindoles via 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)-Catalyzed Aldol Reactions of a Pyruvic Aldehyde Derivative

Synthesis of beta-hydroxyaldehydes with stereogenic quaternary carbon centers by direct organocatalytic asymmetric aldol reactions

scientific article published in April 2004

Synthesis of pyrrolidine-3-carboxylic acid derivatives via asymmetric Michael addition reactions of carboxylate-substituted enones

scientific article

Synthesis ofβ-Hydroxyaldehydes with Stereogenic Quaternary Carbon Centers by Direct Organocatalytic Asymmetric Aldol Reactions

article published in 2004

The Scope of the Direct Proline-Catalyzed Asymmetric Addition of Ketones to Imines

article

The direct organocatalytic asymmetric mannich reaction: unmodified aldehydes as nucleophiles

scientific article

The origin of enantioselectivity in aldolase antibodies: crystal structure, site-directed mutagenesis, and computational analysis

scientific article published in November 2004

Thiazolium-dependent catalytic antibodies produced using a covalent modification strategy†

Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task

scientific article published on April 2000

Visualizing antibody-catalyzed retro-aldol-retro-Michael reactions

scientific article published in November 2001

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