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List of works by Bruno Gran

A GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune Suppression

scientific article published on 27 July 2012

A different response to cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infection in UK people with multiple sclerosis (PwMS) compared to controls

scientific article published on 31 October 2019

A paradoxical role of APCs in the induction of intravenous tolerance in experimental autoimmune encephalomyelitis

scientific article published on 01 April 2005

A presentation of cerebritis secondary to granulomatosis with polyangiitis (wegener)

scientific article

Accelerated and enhanced effect of CCR5-transduced bone marrow neural stem cells on autoimmune encephalomyelitis

scientific article published on 22 April 2012

An Absence of Epstein-Barr Virus Reactivation and Associations with Disease Activity in People with Multiple Sclerosis Undergoing Therapeutic Hookworm Vaccination

scientific article published on 28 August 2020

An Unusual Cause of Cranial Dural Thickening

scientific article published on 29 October 2020

Are current disease-modifying therapeutics in multiple sclerosis justified on the basis of studies in experimental autoimmune encephalomyelitis?

scientific article

Association of apolipoprotein E polymorphism to clinical heterogeneity of multiple sclerosis

scientific article published on 01 December 2000

Atypical progressive multifocal leukoencephalopathy associated with an unusual JC polyomavirus mutation.

scientific article published in August 2009

Bowman-Birk inhibitor suppresses autoimmune inflammation and neuronal loss in a mouse model of multiple sclerosis

scientific article published on 10 June 2008

CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes

scientific article

CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis.

scientific article published on 05 March 2017

Delineating the Role of Toll-Like Receptors in the Neuro-inflammation Model EAE.

scientific article published in January 2016

Detection of skewed T-cell receptor V-beta gene usage in the peripheral blood of patients with multiple sclerosis.

scientific article published in May 1998

Differential expression and regulation of IL-23 and IL-12 subunits and receptors in adult mouse microglia

scientific article published on November 2003

Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis.

scientific article published on 20 October 2011

EAE: imperfect but useful models of multiple sclerosis

scientific article published on 19 January 2011

EBV Infection Empowers Human B Cells for Autoimmunity: Role of Autophagy and Relevance to Multiple Sclerosis.

scientific article published on 7 June 2017

EBV Infection and Multiple Sclerosis: Lessons from a Marmoset Model.

scientific article published on 8 November 2016

Early administration of IL-12 suppresses EAE through induction of interferon-gamma

scientific article published on 01 November 2004

Effect of Fingolimod on Neural Stem Cells: A Novel Mechanism and Broadened Application for Neural Repair

scientific article

Effect of natalizumab on disease progression in secondary progressive multiple sclerosis (ASCEND): a phase 3, randomised, double-blind, placebo-controlled trial with an open-label extension

scientific article

Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis

scientific article published on 09 October 2018

Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells

scientific article

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

scientific article published on 01 October 2000

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).

scientific article published on October 2011

Exploring immunological specificity using synthetic peptide combinatorial libraries.

scientific article

Expression of activity-dependent neuroprotective protein in the immune system: possible functions and relevance to multiple sclerosis

scientific article

Fatigue in multiple sclerosis - a brief review.

scientific article published on 27 August 2012

Glatiramer acetate induces a Th2-biased response and crossreactivity with myelin basic protein in patients with MS.

scientific article

Glucosamine abrogates the acute phase of experimental autoimmune encephalomyelitis by induction of Th2 response

scientific article

Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis

scientific article

Hemispheric asymmetry for the auditory recognition of true and false statements

scientific article published on 01 August 1993

Hemispheric specialization for semantic and syntactic components of language in simultaneous interpreters

scientific article published on July 1991

Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial

scientific article published on 15 June 2020

Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect?

scientific article published on April 2017

Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature.

scientific article

IDO upregulates regulatory T cells via tryptophan catabolite and suppresses encephalitogenic T cell responses in experimental autoimmune encephalomyelitis

scientific article

IL-27 subunits and its receptor (WSX-1) mRNAs are markedly up-regulated in inflammatory cells in the CNS during experimental autoimmune encephalomyelitis.

scientific article

Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease

scientific article

Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis

scientific article

Immunosuppressive activity of 13-cis-retinoic acid in rats: aspects of pharmacokinetics and pharmacodynamics

scientific article published in October 1997

Increase of Ki-67+ natural killer cells in multiple sclerosis patients treated with interferon-β and interferon-β combined with low-dose oral steroids

scientific article published on 08 June 2011

Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis

scientific article published on 18 July 2020

Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia

scientific article published on 26 September 2006

Increased levels of interleukins 2 and 17 in the cerebrospinal fluid of patients with idiopathic intracranial hypertension

scientific article published on 16 October 2013

Inducible IL-23p19 expression in human microglia via p38 MAPK and NF-kappaB signal pathways

scientific article published on 17 October 2007

Induction of distinct neurologic disease manifestations during relapsing fever requires T lymphocytes.

scientific article published on 9 April 2010

Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones.

scientific article published in July 1998

Innate immune regulation of autoimmunity in multiple sclerosis: Focus on the role of Toll-like receptor 2.

scientific article published on 13 December 2016

Innate immune responses in the CNS: role of toll-like receptors, mechanisms, and therapeutic opportunities in multiple sclerosis

scientific article published on 28 June 2013

Interaction between cytokines, cannabinoids and the nervous system

scientific article published on 04 January 2010

Interferon regulatory factor (IRF) 3 is critical for the development of experimental autoimmune encephalomyelitis

scientific article

Intranasal Delivery of Neural Stem Cells: A CNS-specific, Non-invasive Cell-based Therapy for Experimental Autoimmune Encephalomyelitis

scientific article published on June 2013

Lymphocryptovirus Infection of Nonhuman Primate B Cells Converts Destructive into Productive Processing of the Pathogenic CD8 T Cell Epitope in Myelin Oligodendrocyte Glycoprotein

scientific article published on 13 July 2016

Modulation of regulatory T cells in health and disease: role of toll-like receptors.

scientific article published on June 2009

Molecular mimicry and multiple sclerosis: degenerate T-cell recognition and the induction of autoimmunity

scientific article

Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders

scientific article published on January 2003

Multiple Sclerosis between Genetics and Infections: Human Endogenous Retroviruses in Monocytes and Macrophages

scientific article

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

scientific article published on 3 October 2014

Multiple sclerosis: autoimmune associations in multiple sclerosis

scientific article published on 01 November 2010

Neural Stem Cells Engineered to Express Three Therapeutic Factors Mediate Recovery from Chronic Stage CNS Autoimmunity

scientific article published on 16 May 2016

Novel therapeutic approaches to autoimmune demyelinating disorders.

scientific article published on January 2011

Pathophysiology of interleukin-23 in experimental autoimmune encephalomyelitis.

scientific article

Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis.

scientific article

Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging

scientific article published on 07 October 2019

Role of the IL-12/IL-23 system in the regulation of T-cell responses in central nervous system inflammatory demyelination

scientific article

Role of the innate immune system in autoimmune inflammatory demyelination

scientific article published on January 2008

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

scientific article published on 11 November 2007

T cell and antibody responses in remitting-relapsing experimental autoimmune encephalomyelitis in (C57BL/6 x SJL) F1 mice

scientific article published in March 2004

T cells, cytokines, and autoantigens in multiple sclerosis.

scientific article

T-cell based immunotherapy in experimental autoimmune encephalomyelitis and multiple sclerosis

scientific article

TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function

scientific article published on 20 July 2011

TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis.

scientific article published on 15 May 2015

TLR2: an innate immune checkpoint in multiple sclerosis.

scientific article published on 8 October 2015

The PD-1/PD-L pathway is up-regulated during IL-12-induced suppression of EAE mediated by IFN-gamma

scientific article published on 23 February 2007

The Soluble Form of Toll-Like Receptor 2 Is Elevated in Serum of Multiple Sclerosis Patients: A Novel Potential Disease Biomarker.

scientific article published on 14 March 2018

The TLR7 agonist, imiquimod, increases IFN-beta production and reduces the severity of experimental autoimmune encephalomyelitis

scientific article published on 6 February 2010

The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis

scientific article

The endocannabinoid system: a revolving plate in neuro-immune interaction in health and disease ⬇️

scientific article published on February 26, 2012

The essential role of T cells in multiple sclerosis: a reappraisal.

scientific article published on March 2014

The primate autoimmune encephalomyelitis model; a bridge between mouse and man.

scientific article published on 18 March 2015

The protease inhibitor, Bowman-Birk Inhibitor, suppresses experimental autoimmune encephalomyelitis: a potential oral therapy for multiple sclerosis

scientific article

Therapeutic effect of baicalin on experimental autoimmune encephalomyelitis is mediated by SOCS3 regulatory pathway

scientific article

Transforming growth factor-beta 1 inhibits the proliferation of rat astrocytes induced by serum and growth factors

scientific article published on 01 January 1995

Urinary tract infections in multiple sclerosis: under-diagnosed and under-treated? A clinical audit at a large University Hospital

scientific article published on 27 February 2014

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