List of works - Chang Lu

A diffusion-based microfluidic device for single-cell RNA-seq

scientific article published on 01 March 2019

A microfluidic cell array with individually addressable culture chambers

scientific article published on 12 June 2008

A microfluidic flow-through device for high throughput electrical lysis of bacterial cells based on continuous dc voltage

scientific article published on 10 March 2006

Cell-type-specific epigenomic variations associated with <i>BRCA1</i> mutation in pre-cancer human breast tissues

scientific article published on 02 February 2022

Characterizing osmotic lysis kinetics under microfluidic hydrodynamic focusing for erythrocyte fragility studies

scientific article published in December 2012

Chemical transfection of cells in picoliter aqueous droplets in fluorocarbon oil.

scientific article published on 17 October 2011

Detecting intracellular translocation of native proteins quantitatively at the single cell level

Detection of kinase translocation using microfluidic electroporative flow cytometry

scientific article

Diffusion-based microfluidic PCR for "one-pot" analysis of cells

scientific article

Droplet sorting based on the number of encapsulated particles using a solenoid valve.

scientific article published on 16 November 2012

Effects of culture condition on epigenomic profiles of brain tumor cells

scientific article published on 07 February 2019

Electroporation of cells in microfluidic droplets

scientific article published in March 2009

Electroporation of mammalian cells in a microfluidic channel with geometric variation

scientific article published in July 2006

Electroporation-based delivery of cell-penetrating peptide conjugates of peptide nucleic acids for antisense inhibition of intracellular bacteria

scientific article published on October 2014

Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding.

scientific article published on October 2014

Epigenomic and transcriptomic analyses reveal differences between low-grade inflammation and severe exhaustion in LPS-challenged murine monocytes

scientific article published on 28 January 2022

Flow effects in the laser-induced thermal loading of optical traps and optofluidic devices.

scientific article

Flow-through electroporation based on constant voltage for large-volume transfection of cells

scientific article published on 29 January 2010

Genomic DNA extraction from cells by electroporation on an integrated microfluidic platform

scientific article

High-throughput and real-time study of single cell electroporation using microfluidics: effects of medium osmolarity

scientific article published in December 2006

Histone modification analysis by chromatin immunoprecipitation from a low number of cells on a microfluidic platform

scientific article published on 13 July 2011

Immunomagnetic separation of tumor initiating cells by screening two surface markers

scientific article published on 11 January 2017

Intracellular tracking of single native molecules with electroporation-delivered quantum dots

scientific article

Kinetics of NF-κB nucleocytoplasmic transport probed by single-cell screening without imaging ⬇️

scientific article published on September 8, 2010

Low-frequency ac electroporation shows strong frequency dependence and yields comparable transfection results to dc electroporation

scientific article published on 10 April 2012

Low-input and multiplexed microfluidic assay reveals epigenomic variation across cerebellum and prefrontal cortex.

scientific article published on 18 April 2018

MOWChIP-seq for low-input and multiplexed profiling of genome-wide histone modifications

scientific article published on 30 October 2019

Microfluidic Low-Input Fluidized-Bed Enabled ChIP-seq Device for Automated and Parallel Analysis of Histone Modifications.

scientific article published on 8 June 2018

Microfluidic MeDIP-seq for low-input methylomic analysis of mammary tumorigenesis in mice

scientific article published on 01 March 2019

Microfluidic Platform for Next-Generation Sequencing Library Preparation with Low-Input Samples

scientific article published on 14 January 2020

Microfluidic chemical cytometry based on modulation of local field strength

scientific article published on 14 July 2006

Microfluidic delivery of small molecules into mammalian cells based on hydrodynamic focusing

scientific article published in May 2008

Microfluidic electroporation for cellular analysis and delivery

scientific article published on October 2013

Microfluidic electroporation for delivery of small molecules and genes into cells using a common DC power supply

scientific article published in June 2008

Microfluidic electroporation for selective release of intracellular molecules at the single-cell level

scientific article

Microfluidic electroporation of tumor and blood cells: observation of nucleus expansion and implications on selective analysis and purging of circulating tumor cells

scientific article published on 5 January 2010

Microfluidic electroporative flow cytometry for studying single-cell biomechanics

scientific article published on 18 September 2008

Microfluidic epigenomic mapping technologies for precision medicine

scientific article published on 24 July 2019

Microfluidics for genome-wide studies involving next generation sequencing.

scientific article

Microfluidics-Based Chromosome Conformation Capture (3C) Technology for Examining Chromatin Organization with a Low Quantity of Cells

scientific article published on 2 March 2018

Modulating DNA adsorption on silica beads using an electrical switch

scientific article published on 19 December 2008

Observing Single Cell NF-κB Dynamics under Stimulant Concentration Gradient ⬇️

scientific article published on January 19, 2012

One-step extraction of subcellular proteins from eukaryotic cells

scientific article published on 14 June 2010

Paramagnetic Structures within a Microfluidic Channel for Enhanced Immunomagnetic Isolation and Surface Patterning of Cells

scientific article

Phenylbutyrate facilitates homeostasis of non-resolving inflammatory macrophages

scientific article published on 11 October 2019

Quantification of bacterial cells based on autofluorescence on a microfluidic platform

scientific article

Quantitative analysis of protein translocations by microfluidic total internal reflection fluorescence flow cytometry

scientific article

Quantitative measurement of quantum dot uptake at the cell population level using microfluidic evanescent-wave-based flow cytometry

scientific article

Quantum dot (QD)-modified carbon tape electrodes for reproducible electrochemiluminescence (ECL) emission on a paper-based platform

scientific article published on 01 March 2012

RNA Extraction from a Mycobacterium under Ultrahigh Electric Field Intensity in a Microfluidic Device

scientific article

Recent advances in electric analysis of cells in microfluidic systems

scientific article published on 12 March 2008

Recent advances in the use of microfluidic technologies for single cell analysis

scientific article published on 24 November 2017

Release of intracellular proteins by electroporation with preserved cell viability

scientific article published on 13 September 2012

Separation of denatured proteins in free solution on a microchip based on differential binding of alkyl sulfates with different carbon chain lengths

scientific article published on 19 November 2004

Single-cell electrical lysis of erythrocytes detects deficiencies in the cytoskeletal protein network

scientific article published on 25 July 2011

Subpopulation-specific machine learning prognosis for underrepresented patients with double prioritized bias correction

scientific article published in 2022

Thermal loading in flow-through electroporation microfluidic devices

scientific article

Total internal reflection fluorescence flow cytometry

scientific article

Transfection of cells using flow-through electroporation based on constant voltage

scientific article published on 21 July 2011

Vortex-assisted DNA delivery

scientific article

nMOWChIP-seq: low-input genome-wide mapping of non-histone targets

scientific article published on 07 April 2022

List of works by Chang Lu

A diffusion-based microfluidic device for single-cell RNA-seq

A microfluidic cell array with individually addressable culture chambers

A microfluidic flow-through device for high throughput electrical lysis of bacterial cells based on continuous dc voltage

Cell-type-specific epigenomic variations associated with <i>BRCA1</i> mutation in pre-cancer human breast tissues

Characterizing osmotic lysis kinetics under microfluidic hydrodynamic focusing for erythrocyte fragility studies

Chemical transfection of cells in picoliter aqueous droplets in fluorocarbon oil.

Detecting intracellular translocation of native proteins quantitatively at the single cell level

Detection of kinase translocation using microfluidic electroporative flow cytometry

Diffusion-based microfluidic PCR for "one-pot" analysis of cells

Droplet sorting based on the number of encapsulated particles using a solenoid valve.

Effects of culture condition on epigenomic profiles of brain tumor cells

Electroporation of cells in microfluidic droplets

Electroporation of mammalian cells in a microfluidic channel with geometric variation

Electroporation-based delivery of cell-penetrating peptide conjugates of peptide nucleic acids for antisense inhibition of intracellular bacteria

Electroporation-delivered fluorescent protein biosensors for probing molecular activities in cells without genetic encoding.

Epigenomic and transcriptomic analyses reveal differences between low-grade inflammation and severe exhaustion in LPS-challenged murine monocytes

Flow effects in the laser-induced thermal loading of optical traps and optofluidic devices.

Flow-through electroporation based on constant voltage for large-volume transfection of cells

Genomic DNA extraction from cells by electroporation on an integrated microfluidic platform

High-throughput and real-time study of single cell electroporation using microfluidics: effects of medium osmolarity

Histone modification analysis by chromatin immunoprecipitation from a low number of cells on a microfluidic platform

Immunomagnetic separation of tumor initiating cells by screening two surface markers

Intracellular tracking of single native molecules with electroporation-delivered quantum dots

Kinetics of NF-κB nucleocytoplasmic transport probed by single-cell screening without imaging ⬇️

Low-frequency ac electroporation shows strong frequency dependence and yields comparable transfection results to dc electroporation

Low-input and multiplexed microfluidic assay reveals epigenomic variation across cerebellum and prefrontal cortex.

MOWChIP-seq for low-input and multiplexed profiling of genome-wide histone modifications

Microfluidic Low-Input Fluidized-Bed Enabled ChIP-seq Device for Automated and Parallel Analysis of Histone Modifications.

Microfluidic MeDIP-seq for low-input methylomic analysis of mammary tumorigenesis in mice

Microfluidic Platform for Next-Generation Sequencing Library Preparation with Low-Input Samples

Microfluidic chemical cytometry based on modulation of local field strength

Microfluidic delivery of small molecules into mammalian cells based on hydrodynamic focusing

Microfluidic electroporation for cellular analysis and delivery

Microfluidic electroporation for delivery of small molecules and genes into cells using a common DC power supply

Microfluidic electroporation for selective release of intracellular molecules at the single-cell level

Microfluidic electroporation of tumor and blood cells: observation of nucleus expansion and implications on selective analysis and purging of circulating tumor cells

Microfluidic electroporative flow cytometry for studying single-cell biomechanics

Microfluidic epigenomic mapping technologies for precision medicine

Microfluidics for genome-wide studies involving next generation sequencing.

Microfluidics-Based Chromosome Conformation Capture (3C) Technology for Examining Chromatin Organization with a Low Quantity of Cells

Modulating DNA adsorption on silica beads using an electrical switch

Observing Single Cell NF-κB Dynamics under Stimulant Concentration Gradient ⬇️

One-step extraction of subcellular proteins from eukaryotic cells

Paramagnetic Structures within a Microfluidic Channel for Enhanced Immunomagnetic Isolation and Surface Patterning of Cells

Phenylbutyrate facilitates homeostasis of non-resolving inflammatory macrophages

Quantification of bacterial cells based on autofluorescence on a microfluidic platform

Quantitative analysis of protein translocations by microfluidic total internal reflection fluorescence flow cytometry

Quantitative measurement of quantum dot uptake at the cell population level using microfluidic evanescent-wave-based flow cytometry

Quantum dot (QD)-modified carbon tape electrodes for reproducible electrochemiluminescence (ECL) emission on a paper-based platform

RNA Extraction from a Mycobacterium under Ultrahigh Electric Field Intensity in a Microfluidic Device

Recent advances in electric analysis of cells in microfluidic systems

Recent advances in the use of microfluidic technologies for single cell analysis

Release of intracellular proteins by electroporation with preserved cell viability

Separation of denatured proteins in free solution on a microchip based on differential binding of alkyl sulfates with different carbon chain lengths

Single-cell electrical lysis of erythrocytes detects deficiencies in the cytoskeletal protein network

Subpopulation-specific machine learning prognosis for underrepresented patients with double prioritized bias correction

Thermal loading in flow-through electroporation microfluidic devices

Total internal reflection fluorescence flow cytometry

Transfection of cells using flow-through electroporation based on constant voltage

Vortex-assisted DNA delivery

nMOWChIP-seq: low-input genome-wide mapping of non-histone targets