List of works by Trevor Kilpatrick

A Brain-Derived Neurotrophic Factor-Based p75NTR Peptide Mimetic Ameliorates Experimental Autoimmune Neuritis Induced Axonal Pathology and Demyelination.

scientific article

A Functional and Neuropathological Testing Paradigm Reveals New Disability-Based Parameters and Histological Features for P0180-190-Induced Experimental Autoimmune Neuritis in C57BL/6 Mice.

scientific article published on 12 January 2017

A genome-wide association study in progressive multiple sclerosis

scientific journal article

A new era in the treatment of multiple sclerosis

scientific article (publication date: 3 August 2015)

A pilot randomized controlled trial of a tailored cognitive behavioural therapy based intervention for depressive symptoms in those newly diagnosed with multiple sclerosis

scientific article

A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis

scientific article (publication date: 26 October 2010)

A randomised controlled trial: outcomes of bladder rehabilitation in persons with multiple sclerosis

scientific article published on 11 June 2010

A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis

scientific article published in October 2011

A role for galanin in human and experimental inflammatory demyelination

scholarly article

A small peptide mimetic of brain-derived neurotrophic factor promotes peripheral myelination.

scientific article published on 24 February 2013

Achievements and obstacles of remyelinating therapies in multiple sclerosis.

scientific article published on 17 November 2017

Adult neural precursor cells from the subventricular zone contribute significantly to oligodendrocyte regeneration and remyelination.

scientific article published in October 2014

Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels.

scientific article

Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients.

scientific article published on 26 January 2007

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

scientific article published on 29 September 2013

Antisaccade performance in patients with multiple sclerosis.

scientific article published on 12 March 2009

Apolipoprotein genotype does not influence MS severity, cognition, or brain atrophy

scientific article published in September 2009

Association of plasma levels of Protein S with disease severity in multiple sclerosis

scientific article

Associations between silicone skin cast score, cumulative sun exposure, and other factors in the ausimmune study: a multicenter Australian study

scientific article published on 20 October 2009

Asthma onset prior to multiple sclerosis and the contribution of sibling exposure in early life

scientific article published on December 2006

Axonally derived matrilin-2 induces proinflammatory responses that exacerbate autoimmune neuroinflammation

scientific article

BDNF exerts contrasting effects on peripheral myelination of NGF-dependent and BDNF-dependent DRG neurons.

scientific article

Brain-derived neurotrophic factor promotes central nervous system myelination via a direct effect upon oligodendrocytes

scientific article published on 01 January 2010

CD127 immunophenotyping suggests altered CD4+ T cell regulation in primary progressive multiple sclerosis

scientific article published on 11 April 2008

Ceruloplasmin gene-deficient mice with experimental autoimmune encephalomyelitis show attenuated early disease evolution.

scientific article

Chopper, a New Death Domain of the p75 Neurotrophin Receptor That Mediates Rapid Neuronal Cell Death

scientific article published in Journal of Biological Chemistry

Cladribine followed by autologous stem-cell transplantation in progressive multiple sclerosis

scientific article published in January 2004

Cloned multipotential precursors from the mouse cerebrum require FGF-2, whereas glial restricted precursors are stimulated with either FGF-2 or EGF

scientific journal article

Common and Low Frequency Variants in MERTK Are Independently Associated with Multiple Sclerosis Susceptibility with Discordant Association Dependent upon HLA-DRB1*15:01 Status.

scientific article

Control of visually guided saccades in multiple sclerosis: Disruption to higher-order processes.

scientific article published on 7 February 2009

Correction: Optic Nerve Magnetisation Transfer Ratio after Acute Optic Neuritis Predicts Axonal and Visual Outcomes

scientific article (publication date: 28 December 2012)

Current and past Epstein-Barr virus infection in risk of initial CNS demyelination

scientific article published on 13 July 2011

Diffusion tensor imaging correlates of visual impairment in multiple sclerosis and chronic optic neuritis.

scientific article published on 21 February 2012

Diffusion tensor imaging of acute inflammatory lesion evolution in multiple sclerosis.

scientific article published on 16 October 2012

Diffusion tensor imaging of the optic radiations after optic neuritis

scientific article published on 13 September 2011

Dysequilibrium of the PTH-FGF23-vitamin D axis in relapsing remitting multiple sclerosis; a longitudinal study.

scientific article

Early-life hygiene-related factors affect risk of central nervous system demyelination and asthma differentially

scientific article published in June 2013

Effectiveness of rehabilitation intervention in persons with multiple sclerosis: a randomised controlled trial.

scientific article published on 5 June 2008

Endogenous leukemia inhibitory factor production limits autoimmune demyelination and oligodendrocyte loss

article

Endogenously regulated Dab2 worsens inflammatory injury in experimental autoimmune encephalomyelitis

scientific article published on 09 July 2013

EphA4 (Sek1) receptor tyrosine kinase is required for the development of the corticospinal tract

scientific journal article

EphA4 receptor tyrosine kinase is a modulator of onset and disease severity of experimental autoimmune encephalomyelitis (EAE)

scientific article

Exposure to infant siblings during early life and risk of multiple sclerosis

scientific article published on January 2005

Expression of the Tyro4/Mek4/Cek4 gene specifically marks a subset of embryonic motor neurons and their muscle targets.

scientific article

Expression of the low-affinity neurotrophin receptor, p75(NTR), is upregulated by oligodendroglial progenitors adjacent to the subventricular zone in response to demyelination

scientific article published on 01 October 2004

Extended haplotype analysis in the HLA complex reveals an increased frequency of the HFE-C282Y mutation in individuals with multiple sclerosis

scientific article published on 11 March 2004

Factors regulating the differentiation of neural precursors in the forebrain.

scientific article published on January 1995

Fibre-specific white matter changes in multiple sclerosis patients with optic neuritis.

scientific article published on 29 September 2017

Fine mapping of multiple sclerosis susceptibility genes provides evidence of allelic heterogeneity at the IL2RA locus.

scientific article

Fyn is an intermediate kinase that BDNF utilizes to promote oligodendrocyte myelination.

scientific article published on 9 October 2015

Gait and balance deterioration over a 12-month period in multiple sclerosis patients with EDSS scores ≤ 3.0.

scientific article published on 6 February 2017

Gait and balance impairment in early multiple sclerosis in the absence of clinical disability

scientific article published on 01 October 2006

Galanin is an autocrine myelin and oligodendrocyte trophic signal induced by leukemia inhibitory factor

scientific article published on 29 January 2015

Gas6 deficiency increases oligodendrocyte loss and microglial activation in response to cuprizone-induced demyelination.

scientific article published on May 2008

Gas6 increases myelination by oligodendrocytes and its deficiency delays recovery following cuprizone-induced demyelination

scientific article

Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Genome sequencing uncovers phenocopies in primary progressive multiple sclerosis

scientific article published on 03 July 2018

Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci

scientific article

HLA-DRB1 associations with disease susceptibility and clinical course in Australians with multiple sclerosis.

scientific article published on 21 April 2009

Haplotypes of the interleukin 7 receptor alpha gene are correlated with altered expression in whole blood cells in multiple sclerosis.

scientific article published on 11 October 2007

Heterogeneity at the HLA-DRB1 allelic variation locus does not influence multiple sclerosis disease severity, brain atrophy or cognition

scientific article published on 13 December 2010

Illness perception and health-related quality of life in multiple sclerosis.

scientific article published on 11 September 2007

Immunosuppressive therapy is valuable in aggressive multiple sclerosis

scientific article published on 01 November 2000

Induction of postnatal schwann cell death by the low-affinity neurotrophin receptor in vitro and after axotomy.

scientific article published in August 2000

Influence of methylprednisolone on magnetic resonance and histological measures during cuprizone-induced demyelination

scientific article published on 30 July 2010

Inhibitory saccadic dysfunction is associated with cerebellar injury in multiple sclerosis.

scientific article published on 3 September 2013

Interleukin-2 receptor-α proximal promoter hypomethylation is associated with multiple sclerosis

scientific article

LIF potentiates the NT-3-mediated survival of spiral ganglia neurones in vitro

scientific article published on 01 May 1997

LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival

scientific article published on 01 June 2002

LIF receptor signaling modulates neural stem cell renewal

scientific article published in November 2004

Latitudinal variation in incidence and type of first central nervous system demyelinating events

scientific article

Leukaemia Inhibitory Factor or Related Factors Promote the Differentiation of Neuronal and Astrocytic Precursors within the Developing Murine Spinal Cord

scientific article published on 01 February 1996

Leukaemia inhibitory factor abrogates Paclitaxel-induced axonal atrophy in the Wistar rat

scientific article published on 01 August 2001

Leukemia Inhibitory Factor Is an Autocrine Survival Factor for Schwann Cells

scientific article published on 01 July 1999

Leukemia inhibitory factor promotes the neuronal development of spinal cord precursors from the neural tube

scientific article published on November 1, 1992

Leukemia inhibitory factor protects axons in experimental autoimmune encephalomyelitis via an oligodendrocyte-independent mechanism

scientific article

Leukemia inhibitory factor signaling modulates both central nervous system demyelination and myelin repair

scientific article published on 01 April 2008

Longitudinal assessment of antisaccades in patients with multiple sclerosis

scientific article

MR diffusion changes correlate with ultra-structurally defined axonal degeneration in murine optic nerve.

scientific article published on 13 July 2007

MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model.

scientific article

Measurement of intracellular cytokines in MS patients treated with beta-interferon and association of a beta-interferon induced exacerbation with increased expression of gamma-interferon by monocytes

scientific article published on 01 September 2001

Modulation of bone morphogenic protein signalling alters numbers of astrocytes and oligodendroglia in the subventricular zone during cuprizone-induced demyelination.

scientific article published in October 2010

Molecular mechanisms regulating motor neuron development and degeneration.

scientific article

MonoMac syndrome with associated neurological deficits and longitudinally extensive cord lesion.

scientific article published on 21 April 2018

Multidisciplinary rehabilitation for adults with multiple sclerosis

scientific article

Multidisciplinary rehabilitation for adults with multiple sclerosis

scientific article (publication date: 18 April 2007)

Multidisciplinary rehabilitation for adults with multiple sclerosis

scientific article (publication date: February 2008)

Multiple Sclerosis Severity Score: using disability and disease duration to rate disease severity.

scientific article

Multiple Sclerosis: Basic and Clinical.

scientific article

Multiple sclerosis susceptibility-associated SNPs do not influence disease severity measures in a cohort of Australian MS patients

scientific article

Multiple sclerosis: Cognition and saccadic eye movements.

scientific article published in November 2008

Multiple sclerosis: disability profile and quality of life in an Australian community cohort

scientific article published on June 2006

Myelin gene regulatory factor is required for maintenance of myelin and mature oligodendrocyte identity in the adult CNS

scientific article

Nanodiamonds with silicon vacancy defects for nontoxic photostable fluorescent labeling of neural precursor cells

scientific article published in October 2013

Ndrg1 in development and maintenance of the myelin sheath

scientific article published on 12 February 2011

Neural transplantation for Parkinson's disease: a critical appraisal.

scientific article published on August 1991

Neurotrophin receptor homolog-2 regulates nerve growth factor signaling

scientific article published on 04 July 2008

New treatments for multiple sclerosis.

scientific article

Observational analytic studies in multiple sclerosis: controlling bias through study design and conduct. The Australian Multicentre Study of Environment and Immune Function.

scientific article published on August 2007

Occupational exposure and risk of central nervous system demyelination.

scientific article published on 12 April 2013

Offspring number, pregnancy, and risk of a first clinical demyelinating event: the AusImmune Study.

scientific article published on 7 March 2012

Oligodendrocyte positioning in cerebral cortex is independent of projection neuron layering.

scientific article

Oligodendrocytes exhibit selective expression of suppressor of cytokine signaling genes and signal transducer and activator of transcription 1 independent inhibition of interferon-gamma-induced toxicity in response to leukemia inhibitory factor

article

Oligodendroglial expression of TrkB independently regulates myelination and progenitor cell proliferation.

scientific article published in March 2013

On the utility of data from the International HapMap Project for Australian association studies.

scientific article

Optic nerve diffusion changes and atrophy jointly predict visual dysfunction after optic neuritis

scientific article published on 07 January 2009

Optic nerve diffusion tensor imaging after acute optic neuritis predicts axonal and visual outcomes

scientific article

Optic nerve magnetisation transfer ratio after acute optic neuritis predicts axonal and visual outcomes.

scientific article

Parallel changes in structural and functional measures of optic nerve myelination after optic neuritis

scientific article published on 28 May 2015

Past exposure to sun, skin phenotype, and risk of multiple sclerosis: case-control study

scientific article

Pharmacogenetic stimulation of neuronal activity increases myelination in an axon-specific manner.

scientific article published on 22 January 2018

Polymorphisms in the receptor tyrosine kinase MERTK gene are associated with multiple sclerosis susceptibility

scientific article (publication date: 8 February 2011)

Population attributable fractions and joint effects of key risk factors for multiple sclerosis

scientific article published on 21 July 2015

Prospects for stem cell transplantation in multiple sclerosis.

scientific article

Rat oligodendroglia express c-met and focal adhesion kinase, protein tyrosine kinases implicated in regulating epithelial cell motility

scientific article published on 01 January 2000

Regulation of neural precursor differentiation in the embryonic and adult forebrain.

scientific article

Regulation of neural stem cell differentiation in the forebrain

scientific article published in October 1998

Regulation of the early development of the nervous system by growth factors.

scientific article published on January 1994

Remyelination is altered by bone morphogenic protein signaling in demyelinated lesions

scientific article published on 01 March 2011

Replication of KIAA0350, IL2RA, RPL5 and CD58 as multiple sclerosis susceptibility genes in Australians

scientific article published on 24 July 2008

SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians

scientific article published on 30 October 2007

SOCS3 negatively regulates LIF signaling in neural precursor cells

scientific article published on 23 February 2006

Schwann cell apoptosis in the postnatal axotomized sciatic nerve is mediated via NGF through the low-affinity neurotrophin receptor

scientific article published on 01 April 2003

Serial Diffusion Tensor Imaging of the Optic Radiations after Acute Optic Neuritis.

scientific article published on 31 July 2016

Serial MRI in multiple sclerosis: a prospective pilot study of lesion load, whole brain volume and thalamic atrophy

scientific article published in February 2004

Serum phosphorylated neurofilament-heavy chain levels in multiple sclerosis patients

Sex as a determinant of relapse incidence and progressive course of multiple sclerosis

scientific article published on 18 October 2013

Short-term effects of methylprednisolone on cerebral volume in multiple sclerosis relapses

scientific article published on 21 June 2006

Stressful life events and the risk of initial central nervous system demyelination.

scientific article published on 6 September 2016

Sun exposure and vitamin D are independent risk factors for CNS demyelination

scientific article published on 01 February 2011

Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination

scholarly article

Synergy between TGF-beta 3 and NT-3 to promote the survival of spiral ganglia neurones in vitro

scientific article published on 01 January 1998

TAM receptor signalling and demyelination.

scientific article published on 30 September 2009

Targeted ablation of oligodendrocytes induces axonal pathology independent of overt demyelination.

scientific article

Technologies for Advanced Gait and Balance Assessments in People with Multiple Sclerosis

scientific article published in January 2017

The Regulation of Neural Precursor Cells within the Mammalian Brain ⬇️

scientific article published on February 1, 1995

The TAM receptor TYRO3 is a critical regulator of myelin thickness in the central nervous system

scientific article published on 12 September 2018

The TAM receptor Tyro3 regulates myelination in the central nervous system.

scientific article published in February 2017

The engraftment of transplanted primary neuroepithelial cells within the postnatal mouse brain.

scientific article published in November 1994

The multiple sclerosis whole blood mRNA transcriptome and genetic associations indicate dysregulation of specific T cell pathways in pathogenesis

article

The neurotrophins act synergistically with LIF and members of the TGF-beta superfamily to promote the survival of spiral ganglia neurons in vitro

scientific article published on 01 December 1999

The physical anthropometry, lifestyle habits and blood pressure of people presenting with a first clinical demyelinating event compared to controls: the Ausimmune study

scientific article published on 13 May 2013

The role of latitude, ultraviolet radiation exposure and vitamin D in childhood asthma and hayfever: an Australian multicenter study

article

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 1 historical and established therapies. MS Neurology Group of the Australian and New Zealand Association of Neurolo

scientific article published on 30 June 2014

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 2 new and emerging therapies and their efficacy. MS Neurology Group of the Australian and New Zealand Association o

scientific article

Therapeutic approaches to disease modifying therapy for multiple sclerosis in adults: an Australian and New Zealand perspective: part 3 treatment practicalities and recommendations. MS Neurology Group of the Australian and New Zealand Association of

scientific article published on 30 June 2014

Therapeutic potential of LIF in multiple sclerosis

scientific article published on 01 October 2010

Validation of a novel biomarker for acute axonal injury in experimental autoimmune encephalomyelitis.

scientific article

Validation of linear cerebral atrophy markers in multiple sclerosis

scientific article published on 01 February 2008

Vitamin D status: multifactorial contribution of environment, genes and other factors in healthy Australian adults across a latitude gradient

scientific article published on 08 February 2013

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