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List of works by Nikki Jernigan

A new trick for an old dogma: ENaC proteins as mechanotransducers in vascular smooth muscle

scientific article published on February 2008

ASIC proteins regulate smooth muscle cell migration

scientific article published on 25 August 2007

ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry

scientific article published on 29 May 2009

ASIC1-mediated calcium entry stimulates NFATc3 nuclear translocation via PICK1 coupling in pulmonary arterial smooth muscle cells

scientific article published on 17 May 2016

Actin Polymerization Contributes to Enhanced Pulmonary Vasoconstrictor Reactivity Following Chronic Hypoxia.

scientific article published on 26 January 2018

Altered Lipid Domains Facilitate Enhanced Pulmonary Vasoconstriction Following Chronic Hypoxia

scientific article published on 16 January 2020

Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension

scientific article published in January 2017

Angiotensin II regulation of renal vascular ENaC proteins

scientific article published on 26 March 2009

Augmented Pulmonary Vasoconstrictor Reactivity after Chronic Hypoxia Requires Src Kinase and Epidermal Growth Factor Receptor Signaling

scientific article published on 01 January 2020

Calcium homeostasis and sensitization in pulmonary arterial smooth muscle.

scientific article published on April 2014

Cholesterol Regulation of Pulmonary Endothelial Calcium Homeostasis

scientific article published on 08 October 2018

Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation

scientific article

Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.

scientific article

Chronic hypoxia augments protein kinase G-mediated Ca2+ desensitization in pulmonary vascular smooth muscle through inhibition of RhoA/Rho kinase signaling

scientific article

Chronic hypoxia limits H2O2-induced inhibition of ASIC1-dependent store-operated calcium entry in pulmonary arterial smooth muscle

scientific article

Chronic hypoxia upregulates pulmonary arterial ASIC1: a novel mechanism of enhanced store-operated Ca2+ entry and receptor-dependent vasoconstriction

scientific article published on 28 December 2011

Contribution of oxygen radicals to altered NO-dependent pulmonary vasodilation in acute and chronic hypoxia

scientific article published on 12 December 2003

Contribution of reactive oxygen species to the pathogenesis of pulmonary arterial hypertension

scientific article published on 30 June 2017

Correlation of HO-1 expression with onset and reversal of hypoxia-induced vasoconstrictor hyporeactivity

scientific article published in July 2001

Coupling of store-operated calcium entry to vasoconstriction is acid-sensing ion channel 1a dependent in pulmonary but not mesenteric arteries

scientific article published on 23 July 2020

Dietary salt enhances benzamil-sensitive component of myogenic constriction in mesenteric arteries

scientific article published on 16 November 2007

Endothelium-derived reactive oxygen species and endothelin-1 attenuate NO-dependent pulmonary vasodilation following chronic hypoxia

scientific article

Enhanced NO-dependent pulmonary vasodilation limits increased vasoconstrictor sensitivity in neonatal chronic hypoxia.

scientific article

Enhanced depolarization-induced pulmonary vasoconstriction following chronic hypoxia requires EGFR-dependent activation of NAD(P)H oxidase 2

scientific journal article

Impaired NO-dependent inhibition of store- and receptor-operated calcium entry in pulmonary vascular smooth muscle after chronic hypoxia

scientific article published on 21 October 2005

Impaired pressure-induced constriction in mouse middle cerebral arteries of ASIC2 knockout mice

scientific journal article

Interleukin-6 trans-signaling contributes to chronic hypoxia-induced pulmonary hypertension

scientific article published on 16 May 2018

Intermittent Hypoxia Augments Pulmonary Vasoconstrictor Reactivity through PKCβ/Mitochondrial Oxidant Signaling

scientific article published on 12 February 2020

Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen species

scientific article

Loss of acid-sensing ion channel 2 enhances pulmonary vascular resistance and hypoxic pulmonary hypertension

scientific article published on 06 June 2019

Mechanisms of NFATc3 activation by increased superoxide and reduced hydrogen peroxide in pulmonary arterial smooth muscle

scientific article

Membrane depolarization is required for pressure-dependent pulmonary arterial tone but not enhanced vasoconstriction to endothelin-1 following chronic hypoxia

scientific article published on 01 October 2020

Myogenic vasoconstriction in mouse renal interlobar arteries: role of endogenous beta and gammaENaC

scientific article published on 18 July 2006

PICK1/calcineurin suppress ASIC1-mediated Ca2+ entry in rat pulmonary arterial smooth muscle cells

scientific article published on 23 December 2015

PKCβ and reactive oxygen species mediate enhanced pulmonary vasoconstrictor reactivity following chronic hypoxia in neonatal rats

scientific article published on 10 January 2020

Pulmonary PKG-1 is upregulated following chronic hypoxia

scientific article published on 23 May 2003

Reactive oxygen species and RhoA signaling in vascular smooth muscle: role in chronic hypoxia-induced pulmonary hypertension

scientific article published on January 2010

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia

scientific article published on 11 July 2008

Redox Regulation of Ion Channels and Receptors in Pulmonary Hypertension

scientific article published on 25 January 2019

Reduced membrane cholesterol after chronic hypoxia limits Orai1-mediated pulmonary endothelial Ca2+ entry.

scientific article published on 3 November 2017

Reduced membrane cholesterol limits pulmonary endothelial Ca2+ entry after chronic hypoxia

scientific article published on 31 March 2017

Renal vascular responses to CORM-A1 in the mouse

scientific article published on 9 March 2006

RhoA increases ASIC1a plasma membrane localization and calcium influx in pulmonary arterial smooth muscle cells following chronic hypoxia

scientific article

Role of ASIC1 in the development of chronic hypoxia-induced pulmonary hypertension

scientific article

Role of acid-sensing ion channels in hypoxia- and hypercapnia-induced ventilatory responses.

scientific article published on 23 February 2018

Sensing tension: epithelial sodium channel/acid-sensing ion channel proteins in cardiovascular homeostasis

scientific article published on 31 March 2008

Smooth muscle acid-sensing ion channel 1: pathophysiological implication in hypoxic pulmonary hypertension.

scientific article published on 14 January 2015

Vascular ENaC proteins are required for renal myogenic constriction

scientific article published on 24 May 2005

Vasoconstrictor Mechanisms in Chronic Hypoxia-Induced Pulmonary Hypertension: Role of Oxidant Signaling

scientific article published on 15 October 2020

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