List of works - Jos A. G. Van Strijp

A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling.

scientific article

A general sequence independent solid phase method for the site specific synthesis of multiple sulfated-tyrosine containing peptides.

scientific article

A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR.

scientific article published on 21 October 2009

A novel flow cytometric assay to quantify soluble CD14 concentration in human serum

scientific article

Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines.

scientific article published on November 1994

Affinities of different proteins and peptides for lipopolysaccharide as determined by biosensor technology

scientific article published in November 1998

Analysis of lipopolysaccharide (LPS)-binding characteristics of serum components using gel filtration of FITC-labeled LPS.

scientific article published in August 2000

Anti-opsonic properties of staphylokinase

scientific article published on 26 February 2005

Antibodies and complement enhance binding and uptake of HIV-1 by human monocytes

scientific article published on January 1, 1992

Bacterial complement evasion.

scientific article published on 27 July 2006

Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent.

scientific article

Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonuclear leucocytes.

scientific article

Combating Implant Infections: Shifting Focus from Bacteria to Host

scientific article published on 11 September 2020

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

scientific article

Convertase inhibitory properties of Staphylococcal extracellular complement-binding protein.

scientific article

Distinct localization of the complement C5b-9 complex on Gram-positive bacteria

scientific article published on 13 August 2013

Diverging pathways for lipopolysaccharide and CD14 in human monocytes

scientific article published in December 2000

Early expression of SCIN and CHIPS drives instant immune evasion by Staphylococcus aureus

scientific article published in August 2006

Effect of human polymorphonuclear and mononuclear leukocytes on chromosomal and plasmid DNA of Escherichia coli. Role of acid DNase.

scientific article published on May 1984

Effective phagocytosis and killing of Candida albicans via targeting FcgammaRI (CD64) or FcalphaRI (CD89) on neutrophils

scientific article published on 01 March 1999

Entrapment exploited

scientific article published on 31 December 2013

Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3.

scientific article published on 20 June 2012

Functional basis for complement evasion by staphylococcal superantigen-like 7.

scientific article

Fusion of the Fc part of human IgG1 to CD14 enhances its binding to gram-negative bacteria and mediates phagocytosis by Fc receptors of neutrophils

scientific article published on 2 May 2012

How microorganisms avoid phagocyte attraction

scientific article

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

scientific article published in March 2021

Identification and structural characterization of a novel myeloperoxidase inhibitor from Staphylococcus delphini

scientific article published on 7 March 2018

Identification of an immunomodulating metalloprotease of Pseudomonas aeruginosa (IMPa)

scientific journal article

Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases

scientific article published on 07 August 2005

Inhibition of Pseudomonas aeruginosa virulence: characterization of the AprA-AprI interface and species selectivity.

scientific article published on 29 November 2011

Integrin modulating factor-1: a lipid that alters the function of leukocyte integrins

scientific article published on 01 January 1992

Intravital two-photon microscopy of host-pathogen interactions in a mouse model of Staphylococcus aureus skin abscess formation

scientific article published on 24 December 2012

Lipoprotein metabolism in patients with severe sepsis

scientific article published in May 2003

Lipoteichoic acid from is a potent stimulus for neutrophil recruitment

scientific article published on 01 January 2003

Molecular mechanisms of complement evasion: learning from staphylococci and meningococci

scientific article published in June 2010

MprF-mediated lysinylation of phospholipids in Staphylococcus aureus leads to protection against oxygen-independent neutrophil killing.

scientific article

Neutralization of Neisseria meningitidis outer membrane vesicles

scientific article published on 24 May 2011

Pneumococcal immune evasion: ZmpC inhibits neutrophil influx

scientific article published on 3 May 2013

Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA.

scientific article published in July 2014

Recognition of LPS by TLR4: potential for anti-inflammatory therapies.

scientific article

Residues 10-18 within the C5a receptor N terminus compose a binding domain for chemotaxis inhibitory protein of Staphylococcus aureus.

scientific article

Serum amyloid P component bound to gram-negative bacteria prevents lipopolysaccharide-mediated classical pathway complement activation

scientific article published on April 2000

Serum amyloid P component prevents high-density lipoprotein-mediated neutralization of lipopolysaccharide.

scientific article published on September 2000

Spare CD14 molecules on human monocytes enhance the sensitivity for low LPS concentrations

scientific article

Staphylococcal SSL5 binding to human leukemia cells inhibits cell adhesion to endothelial cells and platelets

scientific article

Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins.

scientific article

Staphylococcal alpha-phenol soluble modulins contribute to neutrophil lysis after phagocytosis.

scientific article

Staphylococcal complement evasion by various convertase-blocking molecules.

scientific article

Staphylococcal complement inhibitor modulates phagocyte responses by dimerization of convertases.

scientific article published on 30 November 2009

Staphylococcal innate immune evasion.

scientific article

Staphylococcal superantigen-like 10 inhibits CXCL12-induced human tumor cell migration.

scientific article published on April 2009

Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.

scientific article published in April 2007

Staphylococci evade the innate immune response by disarming neutrophils and forming biofilms

scientific article published on 06 March 2020

Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.

scientific article

Staphylococcus aureus elaborates leukocidin AB to mediate escape from within human neutrophils

scientific article published on 18 March 2013

Staphylococcus aureus formyl peptide receptor-like 1 inhibitor (FLIPr) and its homologue FLIPr-like are potent FcγR antagonists that inhibit IgG-mediated effector functions.

scientific article

Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion

scientific article published on 18 April 2011

Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.

scientific article

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects

scientific article published on 15 October 2018

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

scientific article

Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus

scientific article

The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils

scientific article published on 08 January 2020

The Skn7 response regulator of Cryptococcus neoformans is involved in oxidative stress signalling and augments intracellular survival in endothelium.

scientific article

The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are located on beta-hemolysin-converting bacteriophages.

scientific article

The role of high density lipoprotein in sepsis.

scientific article

The role of tumour necrosis factor in the kinetics of lipopolysaccharide-mediated neutrophil priming in whole blood

scientific article published in April 2005

The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors.

scientific article published on May 2013

The use of a hybridization assay for the study of host defences against herpes simplex virus

scientific article published in December 1989

List of works by Jos A. G. Van Strijp

A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling.

A general sequence independent solid phase method for the site specific synthesis of multiple sulfated-tyrosine containing peptides.

A homolog of formyl peptide receptor-like 1 (FPRL1) inhibitor from Staphylococcus aureus (FPRL1 inhibitory protein) that inhibits FPRL1 and FPR.

A novel flow cytometric assay to quantify soluble CD14 concentration in human serum

Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines.

Affinities of different proteins and peptides for lipopolysaccharide as determined by biosensor technology

Analysis of lipopolysaccharide (LPS)-binding characteristics of serum components using gel filtration of FITC-labeled LPS.

Anti-opsonic properties of staphylokinase

Antibodies and complement enhance binding and uptake of HIV-1 by human monocytes

Bacterial complement evasion.

Chemotaxis inhibitory protein of Staphylococcus aureus, a bacterial antiinflammatory agent.

Clumping factor A of Staphylococcus aureus inhibits phagocytosis by human polymorphonuclear leucocytes.

Combating Implant Infections: Shifting Focus from Bacteria to Host

Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.

Convertase inhibitory properties of Staphylococcal extracellular complement-binding protein.

Distinct localization of the complement C5b-9 complex on Gram-positive bacteria

Diverging pathways for lipopolysaccharide and CD14 in human monocytes

Early expression of SCIN and CHIPS drives instant immune evasion by Staphylococcus aureus

Effect of human polymorphonuclear and mononuclear leukocytes on chromosomal and plasmid DNA of Escherichia coli. Role of acid DNase.

Effective phagocytosis and killing of Candida albicans via targeting FcgammaRI (CD64) or FcalphaRI (CD89) on neutrophils

Entrapment exploited

Evasion of Toll-like receptor 2 activation by staphylococcal superantigen-like protein 3.

Functional basis for complement evasion by staphylococcal superantigen-like 7.

Fusion of the Fc part of human IgG1 to CD14 enhances its binding to gram-negative bacteria and mediates phagocytosis by Fc receptors of neutrophils

How microorganisms avoid phagocyte attraction

Human-specific staphylococcal virulence factors enhance pathogenicity in a humanised zebrafish C5a receptor model

Identification and structural characterization of a novel myeloperoxidase inhibitor from Staphylococcus delphini

Identification of an immunomodulating metalloprotease of Pseudomonas aeruginosa (IMPa)

Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases

Inhibition of Pseudomonas aeruginosa virulence: characterization of the AprA-AprI interface and species selectivity.

Integrin modulating factor-1: a lipid that alters the function of leukocyte integrins

Intravital two-photon microscopy of host-pathogen interactions in a mouse model of Staphylococcus aureus skin abscess formation

Lipoprotein metabolism in patients with severe sepsis

Lipoteichoic acid from is a potent stimulus for neutrophil recruitment

Molecular mechanisms of complement evasion: learning from staphylococci and meningococci

MprF-mediated lysinylation of phospholipids in Staphylococcus aureus leads to protection against oxygen-independent neutrophil killing.

Neutralization of Neisseria meningitidis outer membrane vesicles

Pneumococcal immune evasion: ZmpC inhibits neutrophil influx

Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA.

Recognition of LPS by TLR4: potential for anti-inflammatory therapies.

Residues 10-18 within the C5a receptor N terminus compose a binding domain for chemotaxis inhibitory protein of Staphylococcus aureus.

Serum amyloid P component bound to gram-negative bacteria prevents lipopolysaccharide-mediated classical pathway complement activation

Serum amyloid P component prevents high-density lipoprotein-mediated neutralization of lipopolysaccharide.

Spare CD14 molecules on human monocytes enhance the sensitivity for low LPS concentrations

Staphylococcal SSL5 binding to human leukemia cells inhibits cell adhesion to endothelial cells and platelets

Staphylococcal SSL5 inhibits leukocyte activation by chemokines and anaphylatoxins.

Staphylococcal alpha-phenol soluble modulins contribute to neutrophil lysis after phagocytosis.

Staphylococcal complement evasion by various convertase-blocking molecules.

Staphylococcal complement inhibitor modulates phagocyte responses by dimerization of convertases.

Staphylococcal innate immune evasion.

Staphylococcal superantigen-like 10 inhibits CXCL12-induced human tumor cell migration.

Staphylococcal superantigen-like 5 binds PSGL-1 and inhibits P-selectin-mediated neutrophil rolling.

Staphylococci evade the innate immune response by disarming neutrophils and forming biofilms

Staphylococcus aureus Staphopain A inhibits CXCR2-dependent neutrophil activation and chemotaxis.

Staphylococcus aureus elaborates leukocidin AB to mediate escape from within human neutrophils

Staphylococcus aureus formyl peptide receptor-like 1 inhibitor (FLIPr) and its homologue FLIPr-like are potent FcγR antagonists that inhibit IgG-mediated effector functions.

Staphylococcus aureus metalloprotease aureolysin cleaves complement C3 to mediate immune evasion

Staphylococcus aureus strains lacking D-alanine modifications of teichoic acids are highly susceptible to human neutrophil killing and are virulence attenuated in mice.

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human group IIA secreted phospholipase A2 to exert its bactericidal effects

Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor

Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus

The Orphan Immune Receptor LILRB3 Modulates Fc Receptor-Mediated Functions of Neutrophils

The Skn7 response regulator of Cryptococcus neoformans is involved in oxidative stress signalling and augments intracellular survival in endothelium.

The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are located on beta-hemolysin-converting bacteriophages.

The role of high density lipoprotein in sepsis.

The role of tumour necrosis factor in the kinetics of lipopolysaccharide-mediated neutrophil priming in whole blood

The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors.

The use of a hybridization assay for the study of host defences against herpes simplex virus