List of works - Gregory Oakley

2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity

scientific article

A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A.

scientific article

DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage

scientific article published in June 2005

DNA damage induced hyperphosphorylation of replication protein A. 2. Characterization of DNA binding activity, protein interactions, and activity in DNA replication and repair

scientific article

Deficient DNA damage signaling leads to chemoresistance to cisplatin in oral cancer

scientific article

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress

scientific article

Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts.

scientific article published on January 2001

Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation

scientific article

Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling.

scientific article published on 17 February 2011

Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines

scientific article

Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase

scientific article published on 01 April 1996

NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: a HuGE review

scientific article

NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse

scientific article

Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer

scientific article published on 01 December 1996

Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.

scientific article

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

scientific article

Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks

scientific article published on 4 June 2004

Replication protein A: directing traffic at the intersection of replication and repair

scientific article

Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods

scientific article

Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing

scientific article

Transforming growth factor-β activates c-Myc to promote palatal growth.

scientific article

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

scientific article

Uncoupling-mediated generation of reactive oxygen by halogenated aromatic hydrocarbons in mouse liver microsomes

scientific article published in March 2004

List of works by Gregory Oakley

2,4,4'-trichlorobiphenyl increases STAT5 transcriptional activity

A small molecule directly inhibits the p53 transactivation domain from binding to replication protein A.

DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage

DNA damage induced hyperphosphorylation of replication protein A. 2. Characterization of DNA binding activity, protein interactions, and activity in DNA replication and repair

Deficient DNA damage signaling leads to chemoresistance to cisplatin in oral cancer

Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress

Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts.

Human replication protein A-Rad52-single-stranded DNA complex: stoichiometry and evidence for strand transfer regulation by phosphorylation

Hyaluronan suppresses prostate tumor cell proliferation through diminished expression of N-cadherin and aberrant growth factor receptor signaling.

Hyperphosphorylation of replication protein A in cisplatin-resistant and -sensitive head and neck squamous cell carcinoma cell lines

Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase

NAD(P)H:quinone oxidoreductase (NQO1) polymorphism, exposure to benzene, and predisposition to disease: a HuGE review

NBS1 mediates ATR-dependent RPA hyperphosphorylation following replication-fork stall and collapse

Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer

Physical interaction between replication protein A (RPA) and MRN: involvement of RPA2 phosphorylation and the N-terminus of RPA1.

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

Replication protein A and the Mre11.Rad50.Nbs1 complex co-localize and interact at sites of stalled replication forks

Replication protein A: directing traffic at the intersection of replication and repair

Small molecule inhibitor of the RPA70 N-terminal protein interaction domain discovered using in silico and in vitro methods

Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing

Transforming growth factor-β activates c-Myc to promote palatal growth.

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

Uncoupling-mediated generation of reactive oxygen by halogenated aromatic hydrocarbons in mouse liver microsomes