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List of works by Dominique Gauguier

A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease

scientific article

A dominant modifier of transgene methylation is mapped by QTL analysis to mouse chromosome 13

scientific article

A gene map of the rat derived from linkage analysis and related regions in the mouse and human genomes

scientific article published in July 1999

A gene-based genetic linkage and comparative map of the rat X chromosome

scientific article published in March 1997

A genetic linkage map of the rat derived from recombinant inbred strains

scientific article published on 01 February 1996

A high-resolution consensus linkage map of the rat, integrating radiation hybrid and genetic maps

scientific article published in July 2001

A linkage map of the rat genome derived from three F2 crosses

scientific article published in May 1997

A major quantitative trait locus influences hyperactivity in the WKHA rat.

scientific article published in December 1996

A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry

scientific article published on 29 March 2016

A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist

scientific article published on October 1997

A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice

scientific article published on 6 February 2006

A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock.

scientific article published on 29 October 2008

ANKS3 Co-Localises with ANKS6 in Mouse Renal Cilia and Is Associated with Vasopressin Signaling and Apoptosis In Vivo in Mice

scientific article (publication date: 2015)

Adaptive expression of microRNA-125a in adipose tissue in response to obesity in mice and men.

scientific article

Analysis of 14 Candidate Genes for Diabetic Nephropathy on Chromosome 3q in European Populations: Strongest Evidence for Association With a Variant in the Promoter Region of the Adiponectin Gene

article

Analysis of Quantitative Trait Loci for Blood Pressure on Rat Chromosomes 2 and 13

scientific article published on 01 December 1996

Analysis of distribution in the human, pig, and rat genomes points toward a general subtelomeric origin of minisatellite structures.

scientific article

Applicability of a "speed" congenic strategy to dissect blood pressure quantitative trait loci on rat chromosome 2.

scientific article published in January 2000

Application of quantitative metabolomics in systems genetics in rodent models of complex phenotypes

scientific article published on 18 September 2015

Approaches to the analysis of complex quantitative phenotypes and marker map construction based on the analysis of rat models of hypertension

scientific article published on 01 January 2002

Are animal models of diabetes relevant to the study of the genetics of non-insulin-dependent diabetes in humans?

scientific article published on March 1997

Aryl hydrocarbon receptor nuclear translocator-like (BMAL1) is associated with susceptibility to hypertension and type 2 diabetes

scientific article

Association between Angiotensin-Converting Enzyme Gene Polymorphisms and Diabetic Nephropathy: Case-Control, Haplotype, and Family-Based Study in Three European Populations

article

Association of coronary artery disease and chronic kidney disease in Lebanese population

scientific article

Association of hypertension with coronary artery disease onset in the Lebanese population

scientific article

Biological roles of microRNAs in the control of insulin secretion and action

scientific article published on 4 November 2016

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains

scientific article published on 15 March 2011

Caffeine Impact on Metabolic Syndrome Components Is Modulated by a CYP1A2 Variant

scientific article published on 21 November 2015

Characteristics of the aortic elastic network and related phenotypes in seven inbred rat strains

scientific article published on 07 October 2004

Characterization of a major modifier locus for polycystic kidney disease (Modpkdr1) in the Han:SPRD(cy/+) rat in a region conserved with a mouse modifier locus for Alport syndrome

scientific article published in September 2002

Chromosomal Mapping of Genetic Loci Controlling Absence Epilepsy Phenotypes in the WAG/Rij Rat

scientific article published on 01 August 2004

Chromosomal Mapping of Quantitative Trait Loci Controlling Elastin Content in Rat Aorta

scientific article published on 24 January 2005

Chromosomal mapping of genetic loci associated with non-insulin dependent diabetes in the GK rat

scientific article published on 01 January 1996

Chromosomal mapping of pancreatic islet morphological features and regulatory hormones in the spontaneously diabetic (Type 2) Goto-Kakizaki rat

scientific article

Circulating lipid levels and risk of coronary artery disease in a large group of patients undergoing coronary angiography

scientific article published on 01 January 2015

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats ⬇️

scientific article published on May 26, 2013

Comparative analysis of methods for gene transcription profiling data derived from different microarray technologies in rat and mouse models of diabetes

scientific article

Complete genome searches for quantitative trait loci controlling blood pressure and related traits in four segregating populations derived from Dahl hypertensive rats

scientific article published on 01 March 1999

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance

scientific article published on 15 July 2019

Detailed comparative gene map of rat chromosome 1 with mouse and human genomes and physical mapping of an evolutionary chromosomal breakpoint

scientific article published in February 2000

Detection, cloning, and distribution of minisatellites in some mammalian genomes

scientific article

Diabetes quantitative trait locus research: from physiology to genetics and back

article

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

scientific article published on 15 April 2007

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.

scientific article

Dominant gut Prevotella copri in gastrectomised non-obese diabetic Goto-Kakizaki rats improves glucose homeostasis through enhanced FXR signalling

scientific article published on 16 March 2020

Enhanced insulin secretion and cholesterol metabolism in congenic strains of the spontaneously diabetic (Type 2) Goto Kakizaki rat are controlled by independent genetic loci in rat chromosome 8.

scientific article

European rational approach for the genetics of diabetic complications--EURAGEDIC: patient populations and strategy

scientific article (publication date: 2008)

Functional annotations of diabetes nephropathy susceptibility loci through analysis of genome-wide renal gene expression in rat models of diabetes mellitus

scientific article published on 9 July 2009

G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes

scientific article published on 15 July 2008

Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart

scientific article

Genetic Dissection of Region Around the Sa Gene on Rat Chromosome 1

article

Genetic and environmental effects on complex traits in mice

scientific article

Genetic association analysis of inositol polyphosphate phosphatase-like 1 (INPPL1, SHIP2) variants with essential hypertension

scientific article published on 8 June 2007

Genetic control of differential acetylation in diabetic rats

scientific article

Genetic control of plasma lipid levels in a cross derived from normoglycaemic Brown Norway and spontaneously diabetic Goto–Kakizaki rats

scientific article published on 16 September 2006

Genetic influences on the end-stage effector phase of arthritis

scientific article

Genetics and functional genomics of type 2 diabetes mellitus

scientific article

Genome sequencing and genetic mapping to dissect the genetic basis of complex traits

scientific article

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat

scientific article published on 25 July 2013

Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis

scientific article

Genome-wide diversity in the levant reveals recent structuring by culture

scientific article

Genome-wide genetic association of complex traits in heterogeneous stock mice

article

Genomic organization and mutation screening of the human ortholog of Pkdr1 associated with polycystic kidney disease in the rat

scientific article published on 16 March 2008

Genomic organization of the rat Clock gene and sequence analysis in inbred rat strains

scientific article

Genomic regulation of type 2 diabetes endophenotypes: Contribution from genetic studies in the Goto-Kakizaki rat.

scientific article published on 23 August 2017

Global microRNA expression profiles in insulin target tissues in a spontaneous rat model of type 2 diabetes.

scientific article published on 3 March 2010

Glycomics investigation into insulin action

scientific article published on 10 January 2006

Higher Maternal Than Paternal Inheritance of Diabetes in GK Rats

scientific article published on 01 February 1994

Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins

scientific article

Implication of gut microbiota metabolites in cardiovascular and metabolic diseases

scholarly article by Francois Brial published in November 2018

Inheritance of diabetes mellitus as consequence of gestational hyperglycemia in rats

scientific article published in June 1990

Initial steps of insulin signaling and glucose transport are defective in the type 2 diabetic rat heart

scientific article published on February 2004

Insulin Secretion in Adult Rats After Intrauterine Exposure to Mild Hyperglycemia During Late Gestation ⬇️

scientific article published on December 1, 1991

Integrated genetic mapping of 64 rat microsatellite markers from different sources

scientific article published on 01 April 1997

Integration of the human exposome with the human genome to advance medicine

article published in 2018

Integration of the rat recombination and EST maps in the rat genomic sequence and comparative mapping analysis with the mouse genome

scientific article published on April 2004

J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis.

scientific article published on 22 September 2017

Killer cell lectin-like receptors and the natural killer cell gene complex

article

Large scale association analysis identifies three susceptibility loci for coronary artery disease

scientific article (publication date: 2011)

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Linkage and physical mapping of rat microsatellites derived from minisatellite loci

scientific article published in April 1999

Localization of tub and uncoupling proteins (Ucp) 2 and 3 to a region of rat chromosome 1 linked to glucose intolerance and adiposity in the Goto-Kakizaki (GK) type 2 diabetic rat.

scientific article published in November 1998

Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions

scientific article published on May 2017

MWASTools: an R/Bioconductor package for metabolome-wide association studies.

scientific article published on 26 July 2017

Mapping diabetes QTL in an intercross derived from a congenic strain of the Brown Norway and Goto-Kakizaki rats

scientific article published on 12 June 2006

Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains.

scientific article published on October 1995

Marker-assisted congenic screening (MACS): a database tool for the efficient production and characterization of congenic lines

scientific article

Medical Genetics: Revenge of the thrift

article

MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways. ⬇️

scientific article published on 22 December 2016

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

scholarly article

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota.

scientific article published on 20 April 2018

Metabolic retroconversion of trimethylamineN-oxide and the gut microbiota

MicroRNA-125a is over-expressed in insulin target tissues in a spontaneous rat model of Type 2 Diabetes

scientific article

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

scientific article

Microbiome and metabolome features of the cardiometabolic disease spectrum

scientific article published on 17 February 2022

Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high-fat-diet-induced insulin resistance

Missense mutation in sterile alpha motif of novel protein SamCystin is associated with polycystic kidney disease in (cy/+) rat.

scientific article

Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons

scientific article published on 11 September 2017

Métabonomique et cartographie génétique

scientific article published on 01 December 2007

No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis ⬇️

scientific article published on 12 October 2016

Nouveaux outils de cartographie génétique et génomique pour les études des traits complexes chez le rat

scientific article published on 01 May 2008

Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome

scientific article

Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition

scientific article published on 17 January 2008

Pathophysiological, genetic and gene expression features of a novel rodent model of the cardio-metabolic syndrome

scientific article

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice

scientific article

Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine

scientific article published on February 2015

Plasma and urine metabolomic analyses in aortic valve stenosis reveal shared and biofluid-specific changes in metabolite levels

scientific article published on 25 November 2020

Polygenic Control of Idiopathic Generalized Epilepsy Phenotypes in the Genetic Absence Rats from Strasbourg (GAERS)

scientific article published in April 2004

Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome

scientific article

Progress and prospects in rat genetics: a community view.

scientific article

Progression of diet-induced diabetes in C57BL6J mice involves functional dissociation of Ca2(+) channels from secretory vesicles

scientific article

Protease inhibitor 15, a candidate gene for abdominal aortic internal elastic lamina ruptures in the rat.

scientific article

Quantitative trait locus dissection in congenic strains of the Goto-Kakizaki rat identifies a region conserved with diabetes loci in human chromosome 1q.

scientific article

Rat chromosome 9 bears a major susceptibility locus for IgE response

scientific article published on 01 June 2000

Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats

scientific article (publication date: 2014)

SNP and haplotype mapping for genetic analysis in the rat.

scientific article

Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus

scientific article published in August 1997

Serum IgE Concentration and Other Immune Manifestations of Treatment with Gold Salts Are Linked to the MHC and IL4 Regions in the Rat

scientific article published on 01 January 1996

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

scientific article

Studies of congenic lines in the Brown Norway rat model of Th2-mediated immunopathological disorders show that the aurothiopropanol sulfonate-induced immunological disorder (Aiid3) locus on chromosome 9 plays a major role compared to Aiid2 on chromo

scientific article published in May 2004

Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice

article

Successful Isolation of a Rat Chromosome 1 Blood Pressure Quantitative Trait Locus in Reciprocal Congenic Strains

scientific article published on 01 October 1998

T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility

scientific article published on 08 December 2014

The Microbial Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

The Natural Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

scientific article published on 01 February 2020

The SAM domain of ANKS6 has different interacting partners and mutations can induce different cystic phenotypes

scientific article published on 3 June 2015

The cardiovascular effects of salidroside in the Goto-Kakizaki diabetic rat model

The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man

scientific article (publication date: July 2002)

The genes and gene organization of the Ly49 region of the rat natural killer cell gene complex

scientific article

Thymectomy and radiation-induced type 1 diabetes in nonlymphopenic BB rats

scientific article published in October 2002

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

scientific article published on 30 September 2016

Transcriptome Profiling in Rat Inbred Strains and Experimental Cross Reveals Discrepant Genetic Architecture of Genome-Wide Gene Expression.

scientific article published on 19 September 2016

Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: a possible link between ACE genotype and diabetic nephropathy

scientific article published in April 2004

Two polymorphic dinucleotide repeats in the rat dystrophin gene, including the conserved 3' UTR repeat

scientific article published in September 1995

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol

scientific article published on 02 February 2019

Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase

article

Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture

scientific article

[Possible contribution of hyperglycemia in utero to glucose homeostasis disorders in the adult]

scientific article published on 01 January 1997

mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles

scientific article published on 2 April 2015

pJRES Binning Algorithm (JBA): a new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra

article

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