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List of works by Saadeh Suleiman

A loss of taurine and other amino acids from ventricles of patients undergoing bypass surgery.

scientific article

A new method of quantifying glutathione levels in freshly isolated single superfused rat cardiomyocytes.

scientific article

A new methodological sequence to expand and transdifferentiate human umbilical cord blood derived CD133+ cells into a cardiomyocyte-like phenotype

scientific article published in June 2013

A phospholipase A2 inhibitor (Ro 31-4493) prevents protein loss associated with the calcium paradox in isolated guinea pig hearts without effect on contracture, calcium overload, or the currents through L-type calcium channels.

scientific article published in May 1994

Activation of glibenclamide-sensitive ATP-sensitive K+ channels during β-adrenergically induced metabolic stress produces a substrate for atrial tachyarrhythmia

scientific article published on 16 November 2012

Amino acid utilisation and deamination of glutamine and asparagine by Helicobacter pylori

scientific article published on 01 September 1997

Aspartate transporter expression and activity in hypertrophic rat heart and ischaemia-reperfusion injury

scientific article published on 6 February 2004

Basal metabolic state of hearts of patients with congenital heart disease: the effects of cyanosis, age, and pathology.

scientific article published in November 2004

Beating heart coronary revascularization without metabolic myocardial damage

scientific article published on 01 October 1998

Bicuspid Aortic Valve Alters Aortic Protein Expression Profile in Neonatal Coarctation Patients

scientific article published on 16 April 2019

Calcium paradox in guinea-pig ventricular myocytes

scientific article published in July 1997

Calcium paradox in newborn and adult guinea-pig hearts: changes in intracellular taurine and the effects of extracellular magnesium.

scientific article

Cardiac phosphoproteomics during remote ischemic preconditioning: a role for the sarcomeric Z-disk proteins

scientific article

Cardiac taurine and principal amino acids in right and left ventricles of patients with either aortic valve stenosis or coronary artery disease: the importance of diabetes and gender

scientific article

Cardiac troponin I in neonates undergoing the arterial switch operation

scientific article published on 01 December 2002

Cardiac troponin T and troponin I release during coronary artery surgery using cold crystalloid and cold blood cardioplegia

scientific article published in August 1997

Cardioplegic strategies to protect the hypertrophic heart during cardiac surgery ⬇️

scientific article published on September 1, 2011

Cardioprotection during Adult and Pediatric Open Heart Surgery

scientific article published on 23 June 2015

Cardioprotection of neonatal heart using normothermic hyperkalaemia: the importance of delivery and terminal cardioplegia

scientific article published on 25 November 2007

Cardiopulmonary bypass and oxidative stress

scientific article

Cardiopulmonary bypass-induced myocardial reoxygenation injury in pediatric patients with cyanosis

scientific article published on 01 November 2002

Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia

scientific article published on 16 July 2003

Cellular and molecular basis of RV hypertrophy in congenital heart disease

scientific article

Changes in contractile protein expression are linked to ventricular stiffness in infants with pulmonary hypertension or right ventricular hypertrophy due to congenital heart disease

scientific article published on 3 January 2018

Changes in intracellular concentration of amino acids in human saphenous vein during preparation for coronary artery bypass grafting

scientific article published on 01 November 1995

Changes in mitochondrial function induced in isolated guinea-pig ventricular myocytes by calcium overload

scientific article published on 01 May 1994

Changes in myocardial concentration of glutamate and aspartate during coronary artery surgery

scientific article published on 01 March 1997

Changes in myocardial free amino acids during pediatric cardiac surgery: a randomised controlled trial of three cardioplegic techniques

scientific article published on 24 May 2006

Changes in the intracellular concentration of myocardial glutamine in patients undergoing coronary artery bypass surgery using crystalloid and blood cardioplegia

scientific article published on 01 August 1996

Changes in the intracellular free amino acid pool in human saphenous vein tissue culture

scientific article published on 01 May 1996

Characteristics of L-alanine transport in cardiac sarcolemmal vesicles and into isolated cardiac myocytes

scientific article published on 01 August 1998

Characteristics of L-aspartate transport and expression of EAAC-1 in sarcolemmal vesicles and isolated cells from rat heart.

scientific article

Clinically-relevant consecutive treatment with isoproterenol and adenosine protects the failing heart against ischaemia and reperfusion

scientific article

Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery: a randomized controlled trial

scientific article published in August 2002

Consecutive Isoproterenol and Adenosine Treatment Confers Marked Protection against Reperfusion Injury in Adult but Not in Immature Heart: A Role for Glycogen

scientific article published on 7 February 2018

Controlled hyperkalemic reperfusion with magnesium rescues ischemic juvenile hearts by reducing calcium loading

scientific article published on 18 December 2010

Controlled reoxygenation during cardiopulmonary bypass decreases markers of organ damage, inflammation, and oxidative stress in single-ventricle patients undergoing pediatric heart surgery

scientific article published on 6 June 2014

Coronary artery disease progression is associated with increased resistance of hearts and myocytes to cardiac insults

scientific article published on 01 October 2007

Cysteine protects freshly isolated cardiomyocytes against oxidative stress by stimulating glutathione peroxidase.

scientific article published on 17 June 2010

Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis

scientific article published on 01 July 2020

Effect of Teucrium polium boiled leaf extract on intestinal motility and blood pressure

scientific article published on 01 January 1988

Effect of ischaemia and reperfusion on the intracellular concentration of taurine and glutamine in the hearts of patients undergoing coronary artery surgery

scientific article published on 01 March 1997

Effect of regular training on the myocardial and plasma concentrations of taurine and alpha-amino acids in thoroughbred horses

scientific article published on 01 January 1998

Effect of temperature on the rise in intracellular sodium caused by calcium depletion in ferret ventricular muscle and the mechanism of the alleviation of the calcium paradox by hypothermia

scientific article published on 01 November 1990

Expression and activity of the glutamate transporter EAAT2 in cardiac hypertrophy: implications for ischaemia reperfusion injury

scientific article published on 23 May 2006

FTY720 prevents renal T-cell infiltration after ischemia/reperfusion injury

scientific article

Free amino acids in hearts of pediatric patients with congenital heart disease: the effects of cyanosis, age, and pathology

scientific article published in March 2006

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on "New frontiers in cardiovascular research"

scientific article

Functional and cardioprotective effects of simultaneous and individual activation of protein kinase A and Epac

scientific article published on 10 January 2017

Glutamate loading protects freshly isolated and perfused adult cardiomyocytes against intracellular ROS generation

scientific article published in August 2003

Glutamate-loading stimulates metabolic flux and improves cell recovery following chemical hypoxia in isolated cardiomyocytes.

scientific article published in December 2001

Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury

scientific article

Homocysteine Exposure Impairs Myocardial Resistance to Ischaemia Reperfusion and Oxidative Stress.

scientific article published on 2 December 2015

Human cardiac myosin autoantibodies impair myocyte contractility: a cause-and-effect relationship

scientific article published on 01 April 2006

Hypoxic Pulmonary Vasoconstriction in Humans: Tale or Myth.

scientific article published on 24 January 2017

Immediate Hypothermia Reduces Cardiac Troponin I After Hypoxic-Ischemic Encephalopathy in Newborn Pigs ⬇️

scientific article published on October 1, 2011

Infarct size reduction in acute myocardial infarction.

scientific article published on 14 May 2014

Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery

scientific article

Inflammatory response and cardioprotection during open-heart surgery: the importance of anaesthetics

scientific article published on 22 October 2007

Inhibition of Na+-Ca2+ exchange mechanism in cardiac sarcolemmal vesicles by harmaline

scientific article published on 01 January 1987

Interdependence of intracellular taurine and sodium in guinea pig heart

scientific article published on 01 September 1992

Intermittent antegrade hyperkalaemic warm blood cardioplegia supplemented with magnesium prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery

scientific article published in December 1998

Investigating the effect of remote ischaemic preconditioning on biomarkers of stress and injury-related signalling in patients having isolated coronary artery bypass grafting or aortic valve replacement using cardiopulmonary bypass: study protocol f

scientific article published on 23 April 2015

Invited commentary

L-leucine transport in rat heart under normal conditions and effects of a simulated hypoxia

scientific article

Local inhibition of microRNA-24 improves reparative angiogenesis and left ventricle remodeling and function in mice with myocardial infarction

scientific article published on 18 June 2013

Mechanisms underlying the cardioprotective effect of L-cysteine.

scientific article published in September 2005

Metabolic derangement and cardiac injury early after reperfusion following intermittent cross-clamp fibrillation in patients undergoing coronary artery bypass graft surgery using conventional or miniaturized cardiopulmonary bypass.

scientific article

Metabolic differences between hearts of patients with aortic valve disease and hearts of patients with ischaemic disease

scientific article published on 01 November 1998

Mitochondria: a target for myocardial protection.

scientific article

Myocardial injury in hypertrophic hearts of patients undergoing aortic valve surgery using cold or warm blood cardioplegia.

scientific article published in March 2002

Myocardial metabolic changes during pediatric cardiac surgery: a randomized study of 3 cardioplegic techniques.

scientific article

Myocardial protection with intermittent cold blood during aortic valve operation: antegrade versus retrograde delivery

scientific article published in October 2003

Myocardial taurine, development and vulnerability to ischemia

scientific article published on 29 July 2003

NADH fluorescence in isolated guinea-pig and rat cardiomyocytes exposed to low or high stimulation rates and effect of metabolic inhibition with cyanide

scientific article published in July 1998

Neuro-autonomic changes induced by remote ischemic preconditioning (RIPC) in healthy young adults: Implications for stress

scientific article published on 27 July 2019

New concepts in the cardioprotective action of magnesium and taurine during the calcium paradox and ischaemia of the heart.

scientific article published on December 1994

Paradoxical effects of insulin on cardiac L-type calcium current and on contraction at physiological temperature

scientific article published on 01 April 2004

Participation of opioid receptors in the cytoprotective effect of chronic normobaric hypoxia

scientific article published on 10 January 2019

Pathology-related troponin I release and clinical outcome after pediatric open heart surgery.

scientific article

Postoperative acute kidney injury defined by RIFLE criteria predicts early health outcome and long-term survival in patients undergoing redo coronary artery bypass graft surgery.

scientific article published on 27 February 2016

Propofol cardioplegia: A single-center, placebo-controlled, randomized controlled trial.

scientific article

Propofol improves recovery of the isolated working hypertrophic heart from ischaemia-reperfusion

scientific article published on 22 September 2012

Protection of hearts from reperfusion injury by propofol is associated with inhibition of the mitochondrial permeability transition

scientific article published in January 2000

Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia

scientific article published in August 2002

Randomized comparison between normothermic and hypothermic cardiopulmonary bypass in pediatric open-heart surgery.

scientific article published in September 2005

Relationship between perioperative troponin elevation and other indicators of myocardial injury in vascular surgery patients.

scientific article published on 16 January 2006

Remote ischaemic preconditioning in isolated aortic valve and coronary artery bypass surgery: a randomized trial†

scientific article published on 01 May 2019

Remote ischaemic preconditioning: is it a flag on the field?

scientific article published on 04 February 2015

Remote ischemic conditioning: from experimental observation to clinical application: report from the 8th Biennial Hatter Cardiovascular Institute Workshop

scientific article

Remote ischemic preconditioning triggers changes in autonomic nervous system activity: implications for cardioprotection.

scientific article published on February 2017

Short periods of regional ischaemia and reperfusion provoke release of troponin I from the human hearts

scientific article published on 01 June 1999

Shortening cardioplegic arrest time in patients undergoing combined coronary and valve surgery: results from a multicentre randomized controlled trial: the SCAT trial

scientific article published on 24 April 2017

Signalling of DNA damage and cytokines across cell barriers exposed to nanoparticles depends on barrier thickness

scientific article published on 06 November 2011

Stimulation of ICa by basal PKA activity is facilitated by caveolin-3 in cardiac ventricular myocytes

scientific article

Switching back to normal diet following high-fat diet feeding reduces cardiac vulnerability to ischaemia and reperfusion injury.

scientific article published on 16 September 2014

Taurine and the heart.

scientific article

Temperature preconditioning is optimal at 26° C and confers additional protection to hypothermic cardioplegic ischemic arrest

scientific article

Temperature preconditioning of isolated rat hearts--a potent cardioprotective mechanism involving a reduction in oxidative stress and inhibition of the mitochondrial permeability transition pore

scientific article published on 29 March 2007

The calcium paradox: a role for [Na]i, a cellular or tissue basis, a property unique to the Langendorff perfused heart? A bundle of contradictions!

scientific article

The cardiac proteome in patients with congenital ventricular septal defect: A comparative study between right atria and right ventricles

scientific article published on 20 March 2018

The effect of disease on human cardiac protein expression profiles in paired samples from right and left ventricles.

scientific article

The effect of harmaline and related beta-carbolines on the acetylcholine-stimulated contractions of guinea-pig ileum.

scientific article

The effect of harmaline and related harmala alkaloids on ouabain-stimulated contractions of the guinea-pig ileum ⬇️

scientific article published on April 24, 1981

The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration

scientific article published in December 2002

The effects of propofol cardioplegia on blood and myocardial biomarkers of stress and injury in patients with isolated coronary artery bypass grafting or aortic valve replacement using cardiopulmonary bypass: protocol for a single-center randomized c

scientific article published on 08 July 2014

The end of the cold era: from intermittent cold to intermittent warm blood cardioplegia

scientific article published on 01 November 1998

The importance of myocardial amino acids during ischemia and reperfusion in dilated left ventricle of patients with degenerative mitral valve disease.

scientific article

The influence of harmaline on the movements of sodium ions in smooth muscle of the guinea pig ileum.

scientific article

The role of transmembrane sodium gradient in rabbit ileal smooth muscle: utilization of harmaline.

scientific article published in August 1985

The use of Langendorff perfused guinea-pig heart to study the efflux of amino acids from heart cells

scientific article published on 01 August 1996

Warm blood cardioplegia reduces the fall in the intracellular concentration of taurine in the ischaemic/reperfused heart of patients undergoing aortic valve surgery

scientific article published on 01 January 1998

Warm blood hyperkalaemic reperfusion ('hot shot') prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery

scientific article

Warm-blood cardioplegia with low or high magnesium for coronary bypass surgery: a randomised controlled trial.

scientific article

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