List of works - Hirofumi Arakawa

Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.

scientific article published on January 2004

Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers

scientific article published in April 1994

B-cell linker protein prevents aneuploidy by inhibiting cytokinesis

scientific article

BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria

scientific article

Changes in IL-6, IL-8, C-reactive protein and pancreatic secretory trypsin inhibitor after transcatheter arterial chemo-embolization therapy for hepato-cellular carcinoma

scientific article published on 01 November 1992

Cyclin K as a direct transcriptional target of the p53 tumor suppressor

scientific article

Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression

scientific article

Discovery of Mieap-regulated mitochondrial quality control as a new function of tumor suppressor p53

scientific article

Elevation of circulating interleukin 6 after surgery: factors influencing the serum level

scientific article published on 01 March 1994

Elevation of serum group II phospholipase A2 levels in patients with advanced cancer

scientific article published on 01 August 1994

Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors

scientific article

Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene

scientific article

Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control

scientific article published on 24 April 2012

Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

scientific article

Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53.

scientific article

Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway

scientific article

Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.

scientific article published on July 2006

Identification of semaphorin3B as a direct target of p53

scientific article

Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.

scientific article published in April 2002

Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

scientific journal article

Interleukin-8 is constitutively and commonly produced by various human carcinoma cell lines

scientific article published on January 1, 1992

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

scientific article (publication date: 2 November 2001)

Mieap suppresses murine intestinal tumor via its mitochondrial quality control

scientific article published on 28 July 2015

Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria

scientific article

Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer

scientific article published on 4 January 2016

Molecular cloning and expression of a novel human gene that is highly homologous to human FK506-binding protein 12kDa (hFKBP-12) and characterization of two alternatively spliced transcripts

scientific article

Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA

scientific journal article

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

scientific article

Netrin-1 and its receptors in tumorigenesis

scientific article

NuMA is required for the selective induction of p53 target genes

scientific article published on 15 April 2013

Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control

scientific article

Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer

scientific article published on 02 November 2018

Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21.3, in p53-regulated tumor angiogenesis suppression

scientific article published on February 2007

Survivin: A novel marker and potential therapeutic target for human angiosarcoma.

scientific article published on 28 August 2017

The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage

scientific article

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

scientific article

p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

scientific journal article

p53RDL1 regulates p53-dependent apoptosis

scientific article (publication date: March 2003)

p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1

scientific article

List of works by Hirofumi Arakawa

Adenovirus-mediated p53AIP1 gene transfer as a new strategy for treatment of p53-resistant tumors.

Alternative splicing of the NF2 gene and its mutation analysis of breast and colorectal cancers

B-cell linker protein prevents aneuploidy by inhibiting cytokinesis

BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria

Changes in IL-6, IL-8, C-reactive protein and pancreatic secretory trypsin inhibitor after transcatheter arterial chemo-embolization therapy for hepato-cellular carcinoma

Cyclin K as a direct transcriptional target of the p53 tumor suppressor

Dependence receptor UNC5D mediates nerve growth factor depletion-induced neuroblastoma regression

Discovery of Mieap-regulated mitochondrial quality control as a new function of tumor suppressor p53

Elevation of circulating interleukin 6 after surgery: factors influencing the serum level

Elevation of serum group II phospholipase A2 levels in patients with advanced cancer

Germ-line and somatic mutations of the APC gene in patients with Turcot syndrome and analysis of APC mutations in brain tumors

Identification and characterization of the ARP1 gene, a target for the human acute leukemia ALL1 gene

Identification of 14-3-3γ as a Mieap-interacting protein and its role in mitochondrial quality control

Identification of ALDH4 as a p53-inducible gene and its protective role in cellular stresses

Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53.

Identification of STAG1 as a key mediator of a p53-dependent apoptotic pathway

Identification of p53-46F as a super p53 with an enhanced ability to induce p53-dependent apoptosis.

Identification of semaphorin3B as a direct target of p53

Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.

Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

Interleukin-8 is constitutively and commonly produced by various human carcinoma cell lines

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

Mieap suppresses murine intestinal tumor via its mitochondrial quality control

Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria

Mieap-regulated mitochondrial quality control is frequently inactivated in human colorectal cancer

Molecular cloning and expression of a novel human gene that is highly homologous to human FK506-binding protein 12kDa (hFKBP-12) and characterization of two alternatively spliced transcripts

Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

Netrin-1 and its receptors in tumorigenesis

NuMA is required for the selective induction of p53 target genes

Possible existence of lysosome-like organella within mitochondria and its role in mitochondrial quality control

Possible role of p53/Mieap-regulated mitochondrial quality control as a tumor suppressor in human breast cancer

Possible role of semaphorin 3F, a candidate tumor suppressor gene at 3p21.3, in p53-regulated tumor angiogenesis suppression

Survivin: A novel marker and potential therapeutic target for human angiosarcoma.

The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage

p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis

p53RDL1 regulates p53-dependent apoptosis

p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1