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List of works by Laura Via

121. Improving Predictive Value of Phase 2a TB Drug Development Models Through PET/CT Imaging (NexGen EBA)

article

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images.

scientific article published on 25 June 2018

A sterilizing tuberculosis treatment regimen is associated with faster clearance of bacteria in cavitary lesions in marmosets

scientific article published on 4 May 2015

Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues.

scientific article

Additional drug resistance of multidrug-resistant tuberculosis in patients in 9 countries.

scientific article published on June 2015

An In Vitro Caseum Binding Assay that Predicts Drug Penetration in Tuberculosis Lesions

scientific article published on 8 May 2017

Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery

scientific article

Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7.

scientific article

Association between Regimen Composition and Treatment Response in Patients with Multidrug-Resistant Tuberculosis: A Prospective Cohort Study

scientific article (publication date: December 2015)

Association of antigen-stimulated release of tumor necrosis factor-alpha in whole blood with response to chemotherapy in patients with pulmonary multidrug-resistant tuberculosis

scientific article

Association of lipoarabinomannan with high density lipoprotein in blood: implications for diagnostics

scientific article published on 16 March 2013

Author Correction: The wide utility of rabbits as models of human diseases

scientific article published on 04 July 2019

Bacterial Loads Measured by the Xpert MTB/RIF Assay as Markers of Culture Conversion and Bacteriological Cure in Pulmonary TB.

scientific article

Changes in inflammatory protein and lipid mediator profiles persist after antitubercular treatment of pulmonary and extrapulmonary tuberculosis: A prospective cohort study

scientific article published on 18 June 2019

Clinical research and development of tuberculosis diagnostics: moving from silos to synergy

scientific article

Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluoroquinolone and Aminoglycoside Resistance

scientific article

Comparison of methods for isolation of Mycobacterium avium complex DNA for use in PCR and RAPD fingerprinting

article published in 1995

Correction to Absolute Quantitative MALDI Imaging Mass Spectrometry: A Case of Rifampicin in Liver Tissues.

scientific article published on 19 August 2016

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

scientific article published in December 2017

Corrigendum: Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

article

Detection of Isoniazid-, Fluoroquinolone-, Amikacin-, and Kanamycin-Resistant Tuberculosis in an Automated, Multiplexed 10-Color Assay Suitable for Point-of-Care Use.

scientific article

Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus)

scientific article

Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.

scientific article

Effects of cytokines on mycobacterial phagosome maturation

scientific article published on April 1998

Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis

scientific article published on 03 June 2013

Elements of signal transduction in Mycobacterium tuberculosis: in vitro phosphorylation and in vivo expression of the response regulator MtrA

scientific journal article

Essential but not vulnerable: indazole sulfonamides targeting inosine monophosphate dehydrogenase as potential leads against Mycobacterium tuberculosis

scientific article

Evaluation of a Rapid Molecular Drug-Susceptibility Test for Tuberculosis

scientific article published on September 2017

Evaluation of the diagnostic utility of a whole-blood interferon-gamma assay for determining the risk of exposure to Mycobacterium tuberculosis in Bacille Calmette-Guerin (BCG)-vaccinated individuals

scientific article published on 4 March 2008

Exploring alternative biomaterials for diagnosis of pulmonary tuberculosis in HIV-negative patients by use of the GeneXpert MTB/RIF assay

scientific article published on 09 October 2013

Extensive drug resistance acquired during treatment of multidrug-resistant tuberculosis

scientific article

Extensively drug-resistant tuberculosis in South Korea: risk factors and treatment outcomes among patients at a tertiary referral hospital

scientific article published in January 2008

Extreme Drug Tolerance of Mycobacterium tuberculosis in Caseum

scientific article published on 4 December 2017

Fitness costs of rifampicin resistance in Mycobacterium tuberculosis are amplified under conditions of nutrient starvation and compensated by mutation in the β' subunit of RNA polymerase

scientific article published on 26 February 2014

Genetic diversity of Mycobacterium tuberculosis isolates from a tertiary care tuberculosis hospital in South Korea

scientific article

Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

scientific article

Genotypic susceptibility testing of Mycobacterium tuberculosis isolates for amikacin and kanamycin resistance by use of a rapid sloppy molecular beacon-based assay identifies more cases of low-level drug resistance than phenotypic Lowenstein-Jensen t

scholarly article by Soumitesh Chakravorty et al published January 2015 in Journal of Clinical Microbiology

Granzyme B-expressing neutrophils correlate with bacterial load in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques

scientific article

Green fluorescent protein as a marker for gene expression and cell biology of mycobacterial interactions with macrophages

scientific article published on September 1995

Green fluorescent protein. A tool for gene expression and cell biology in mycobacteria

scientific article published on January 1998

High Persister Mutants in Mycobacterium tuberculosis

scientific article

High-sensitivity MALDI-MRM-MS imaging of moxifloxacin distribution in tuberculosis-infected rabbit lungs and granulomatous lesions

scientific article

Host blood RNA signatures predict the outcome of tuberculosis treatment.

scientific article published on 12 August 2017

Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives

scientific article published on May 2015

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

scientific article published on 25 June 2014

Impact of diabetes and smoking on mortality in tuberculosis

scientific article

Improved rapid molecular diagnosis of multidrug-resistant tuberculosis using a new reverse hybridization assay, REBA MTB-MDR.

scientific article

Infection dynamics and response to chemotherapy in a rabbit model of tuberculosis using [¹⁸F]2-fluoro-deoxy-D-glucose positron emission tomography and computed tomography

scientific article

Inflammatory signaling in human tuberculosis granulomas is spatially organized

scientific article

Inhibition of CorA-Dependent Magnesium Homeostasis Is Cidal in Mycobacterium tuberculosis

scientific article published on 23 September 2019

Interleukin (IL)-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms

scientific article published on 3 September 2004

Intratracheal exposure of common marmosets to MERS-CoV Jordan-n3/2012 or MERS-CoV EMC/2012 isolates does not result in lethal disease

scientific article published on 02 September 2015

Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis.

scientific article published on 9 October 2015

Linezolid for treatment of chronic extensively drug-resistant tuberculosis

scientific article

Mathematical Model of Oxygen Transport in Tuberculosis Granulomas

scientific article published on 8 August 2015

Meropenem-clavulanic acid shows activity against Mycobacterium tuberculosis in vivo

scientific article

Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi-drug resistant tuberculosis: a case report

scientific article

Metronidazole prevents reactivation of latent Mycobacterium tuberculosis infection in macaques

scientific article

Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms

scientific article published on 07 June 2013

Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues

scientific article published on 10 March 2022

Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations.

scientific article

Multidrug-Resistant Tuberculosis Treatment Outcomes in Relation to Treatment and Initial Versus Acquired Second-Line Drug Resistance

scientific article

Mutations in extensively drug-resistant Mycobacterium tuberculosis that do not code for known drug-resistance mechanisms.

scientific article

Mutations in gidB confer low-level streptomycin resistance in Mycobacterium tuberculosis

scientific article

Mycobacterial phagosome maturation, rab proteins, and intracellular trafficking.

scientific article published on December 1997

Mycobacterium tuberculosis is a natural mutant with an inactivated oxidative-stress regulatory gene: implications for sensitivity to isoniazid

scientific article

Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice

scientific article (publication date: 2012)

Natural killer cells are recruited during pulmonary tuberculosis and their ex vivo responses to mycobacteria vary between healthy human donors in association with KIR haplotype

scientific article

Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

scientific article

Nuclear imaging: a powerful novel approach for tuberculosis

scientific article

PET/CT imaging correlates with treatment outcome in patients with multidrug-resistant tuberculosis.

scientific article published on December 2014

PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis.

scientific article

Pathology of Tuberculosis in the Human Lung

scholarly article published 17 September 2010

Persisting positron emission tomography lesion activity and Mycobacterium tuberculosis mRNA after tuberculosis cure

scientific article

Pharmacokinetic evaluation of the penetration of antituberculosis agents in rabbit pulmonary lesions

scientific article published on 10 October 2011

Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development

scientific article published on 31 October 2019

Polymorphisms associated with resistance and cross-resistance to aminoglycosides and capreomycin in Mycobacterium tuberculosis isolates from South Korean Patients with drug-resistant tuberculosis

scientific article

Prediction of Drug Penetration in Tuberculosis Lesions

scientific article published on 06 July 2016

Predictors of pulmonary tuberculosis treatment outcomes in South Korea: a prospective cohort study, 2005-2012

scientific article

Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study

scientific article

Quantitative 18F-FDG PET-CT scan characteristics correlate with tuberculosis treatment response

scientific article published on 10 February 2020

Rapid detection of Mycobacterium tuberculosis biomarkers in a sandwich immunoassay format using a waveguide-based optical biosensor.

scientific article

Rapid detection of fluoroquinolone-resistant and heteroresistant Mycobacterium tuberculosis by use of sloppy molecular beacons and dual melting-temperature codes in a real-time PCR assay

scientific article

Rapid, high-throughput detection of rifampin resistance and heteroresistance in Mycobacterium tuberculosis by use of sloppy molecular beacon melting temperature coding

scientific article

Reagent precoated targets for rapid in-tissue derivatization of the anti-tuberculosis drug isoniazid followed by MALDI imaging mass spectrometry

scientific article

Rhabdomyolysis in a patient treated with linezolid for extensively drug-resistant tuberculosis

scientific article

Sensititre MYCOTB MIC plate for testing Mycobacterium tuberculosis susceptibility to first- and second-line drugs

scientific article published on 07 October 2013

Sputum culture conversion as a prognostic marker for end-of-treatment outcome in patients with multidrug-resistant tuberculosis: a secondary analysis of data from two observational cohort studies

scientific article

Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific

scientific article published on 30 August 2018

The Medicinal Chemistry of Tuberculosis Chemotherapy

article

The association between sterilizing activity and drug distribution into tuberculosis lesions

scientific article published on 7 September 2015

The extreme sensitivity of Mycobacterium tuberculosis to the front-line antituberculosis drug isoniazid

scientific article published in November 1996

The transcription factor NFATp plays a key role in susceptibility to TB in mice

scientific article

The wide utility of rabbits as models of human diseases.

scientific article published on 22 May 2018

The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy

scientific article

Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization

scientific article published on 02 April 2019

Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates

scientific article (publication date: June 2008)

Uptake of unnatural trehalose analogs as a reporter for Mycobacterium tuberculosis

scientific article

Using biomarkers to predict TB treatment duration (Predict TB): a prospective, randomized, noninferiority, treatment shortening clinical trial

article

Utility of the REBA MTB-Rifa® assay for rapid detection of rifampicin resistant Mycobacterium tuberculosis

scientific article

Very Low Doses of Mycobacterium tuberculosis Yield Diverse Host Outcomes in Common Marmosets (Callithrix jacchus).

scientific article published on January 2016

Within patient microevolution of Mycobacterium tuberculosis correlates with heterogeneous responses to treatment

scientific article

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