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List of works by Jacek Topczewski

A functional screening of the kinome identifies the Polo-like kinase 4 as a potential therapeutic target for malignant rhabdoid tumors, and possibly, other embryonal tumors of the brain

scientific article

A map of cis-regulatory elements and 3D genome structures in zebrafish

scientific article published on 25 November 2020

A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis

scientific article

A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway

scientific article

ATRT-04. A FUNCTIONAL SCREENING OF THE KINOME IDENTIFIES THE POLO-LIKE KINASE 4 (PLK4) AS A POTENTIAL THERAPEUTIC TARGET FOR ATYPICAL TERATOID/RHABDOID TUMORS (AT/RT), AND POSSIBLY, OTHER EMBRYONAL TUMORS OF THE BRAIN.

scientific article published on 31 May 2017

Abstract 100: Osteoclast Activity Required For Cranial Suture Patency.

scientific article published in April 2018

Abstract 11: Osteoporotic Phenotype of Newly Identified Zebrafish Mutant.

scientific article published in April 2018

Abstract 21: Identifying New Mutations Of Fgfr1a After CRISPR/Cas9 Genome Editing.

scientific article published in April 2017

Abstract 52: mutating fibroblast growth factor receptor 1 (fgfr1) in zebrafish to create a new model of craniosynostosis

scientific article published on 01 March 2014

Abstract 74: characterization of the koliber mutant: a new model for craniosynostosis research

scientific article published on 01 March 2014

Abstract 76: Modeling Craniosynostosis in Zebrafish using the Genome Editing Technique CRISPR.

scientific article published in March 2014

Bisoniana 119. Phylogeny and genetic variation of the European bison Bison bonasus based on mitochondrial DNA D-loop sequences

scientific article published on 5 September 1999

Cloning and characterization of the Aspergillus nidulans cysB gene encoding cysteine synthase

scientific article published in April 1997

Comparison of different numerical treatments for x-ray phase tomography of soft tissue from differential phase projections.

scientific article published on 24 March 2015

Craniofacial skeletal defects of adult zebrafish Glypican 4 (knypek) mutants.

scientific article published on October 2009

Cytoskeletal dynamics of the zebrafish embryo

scientific article published on 01 January 1999

Development and regeneration of the zebrafish maxillary barbel: a novel study system for vertebrate tissue growth and repair

scientific article

Developmentally regulated expression of two members of the Nrarp family in zebrafish

scientific article published on 01 May 2003

Direct activation of chordoblasts by retinoic acid is required for segmented centra mineralization during zebrafish spine development.

scientific article published on 12 April 2018

Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation

scientific article

Divergent requirements for fibroblast growth factor signaling in zebrafish maxillary barbel and caudal fin regeneration

scientific article published on 28 January 2013

Embryonic and tumorigenic pathways converge via Nodal signaling: role in melanoma aggressiveness.

scientific article published on 30 July 2006

Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements

scientific article

Expression of five frizzleds during zebrafish craniofacial development

scientific article published on 10 July 2009

Genotyping of Bison bonasus kappa-casein gene following DNA sequence amplification.

scientific article published in October 1995

Glypican 4 and Mmp14 interact in regulating the migration of anterior endodermal cells by limiting extracellular matrix deposition

scientific article published on 28 August 2018

Head and trunk in zebrafish arise via coinhibition of BMP signaling by bozozok and chordino

scientific article

Identification of an evolutionarily conserved regulatory element of the zebrafish col2a1a gene

scientific article

Identification of an evolutionarily conserved regulatory element of the zebrafish collagen 2 alpha 1a gene

article

Identification of regulatory elements recapitulating early expression of L-plastin in the zebrafish enveloping layer and embryonic periderm

scientific article published on 30 March 2019

Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis

scientific article published on 29 August 2007

Inhibition of neurogenesis at the zebrafish midbrain-hindbrain boundary by the combined and dose-dependent activity of a new hairy/E(spl) gene pair

scientific article

Loss of Sbds in zebrafish leads to neutropenia and pancreas and liver atrophy

scientific article published on 06 August 2020

Loss of col8a1a function during zebrafish embryogenesis results in congenital vertebral malformations.

scientific article published on 11 December 2013

Methods for the study of the zebrafish maxillary barbel

scientific article published on 23 November 2009

Multi-Shell Nano-CarboScavengers for Petroleum Spill Remediation

scientific article

Non-aggregating tau phosphorylation by cyclin-dependent kinase 5 contributes to motor neuron degeneration in spinal muscular atrophy.

scientific article

Notum homolog plays a novel role in primary motor innervation.

scientific article published on January 2013

Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation

scientific article

Peering through zebrafish to understand inherited bone marrow failure syndromes

scholarly article by Usua Oyarbide et al published January 2019 in Haematologica

Peripheral axons of the adult zebrafish maxillary barbel extensively remyelinate during sensory appendage regeneration

scientific article

Planar cell polarity signaling in craniofacial development

scientific article published on October 2011

Regulatory variant in FZD6 gene contributes to nonsyndromic cleft lip and palate in an African-American family

scientific article

Role of the zebrafish trilobite locus in gastrulation movements of convergence and extension

scientific article published in August 2000

Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis

scientific article

Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene

scientific article

Sequence and expression of zebrafish foxc1a and foxc1b, encoding conserved forkhead/winged helix transcription factors

scientific article published in February 2001

Several mutations including two novel mutations of the glucose-6-phosphate dehydrogenase gene in Polish G6PD deficient subjects with chronic nonspherocytic hemolytic anemia, acute hemolytic anemia, and favism

scientific article published on 01 January 1999

Simple, economical heat-shock devices for zebrafish housing racks

scientific article published on 13 September 2011

Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development

scientific article

Structure and regulation of cysD, the homocysteine synthase gene of Aspergillus nidulans

scientific article published in February 1998

Targeted deletion of the zebrafish actin-bundling protein L-plastin (lcp1).

scientific article published on 2 January 2018

Targeted gene expression in the zebrafish prechordal plate

scientific article published on 01 December 2006

The emerging role of Wnt/PCP signaling in organ formation.

scientific article published on March 2009

The winged helix transcription factor Foxc1a is essential for somitogenesis in zebrafish

scientific article

The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures

scientific article published in April 1999

The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension

scientific article published in August 2001

Visualizing morphogenesis in transgenic zebrafish embryos using BODIPY TR methyl ester dye as a vital counterstain for GFP.

scientific article published in February 2005

Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements

scientific article published in June 2002

Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex

scientific article

Zebrafish models of skeletal dysplasia induced by cholesterol biosynthesis deficiency

scientific article published on 19 May 2020

Zebrafish trilobite identifies new roles for Strabismus in gastrulation and neuronal movements.

scientific article

miR-27b controls venous specification and tip cell fate

scientific article published on 29 December 2011