List of works - Kurt W Runge

A Heterochromatin Domain Forms Gradually at a New Telomere and Is Dynamic at Stable Telomeres

scientific article published on 16 July 2018

A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining

scientific article

A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity.

scientific article published on 4 May 2009

A new method to efficiently induce a site‐specific double‐strand break in the fission yeast Schizosaccharomyces pombe ⬇️

scientific article published on June 6, 2012

A new model for vitamin K-dependent carboxylation: the catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine

scholarly article

A two-step model for senescence triggered by a single critically short telomere

scientific article

Brønsted analysis reveals Lys218 as the carboxylase active site base that deprotonates vitamin K hydroquinone to initiate vitamin K-dependent protein carboxylation

scientific article

Editorial: The Evolving Telomeres

scientific article published on 6 April 2016

Generation and analysis of a barcode-tagged insertion mutant library in the fission yeast Schizosaccharomyces pombe

scientific article

Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities.

scientific article published on January 2012

Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants.

scientific article

Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe

scientific article published on 14 March 2017

Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres.

scientific article

Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis ⬇️

scientific article published on February 1, 2012

Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis.

scientific article

Saccharomyces cerevisiae linear chromosome stability (lcs) mutants increase the loss rate of artificial and natural linear chromosomes

scientific article published on 01 February 1993

Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan.

scientific article published on 17 March 2003

TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae

scientific article

Tel1p Preferentially Associates with Short Telomeres to Stimulate Their Elongation

scientific article published on 01 September 2007

Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

scientific article published on 27 August 2019

The C Terminus of the Major Yeast Telomere Binding Protein Rap1p Enhances Telomere Formation ⬇️

scientific article published on March 1, 1998

The ZDS1 and ZDS2 proteins require the Sir3p component of yeast silent chromatin to enhance the stability of short linear centromeric plasmids.

scientific article

The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2)

scientific article published on 09 July 2018

The physiology of vitamin K nutriture and vitamin K-dependent protein function in atherosclerosis.

scientific article

The vitamin K-dependent carboxylase has been acquired by Leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation

scientific article published on August 2005

The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction.

scientific article

The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA ⬇️

scientific article published on March 15, 1998

Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells.

scientific article published on December 1999

Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

scientific article published on 28 March 2018

Yeast telomerase appears to frequently copy the entire template in vivo.

scientific article published on June 2001

Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast

scientific article published on 03 September 2013

r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step.

scientific article published on May 2006

List of works by Kurt W Runge

A Heterochromatin Domain Forms Gradually at a New Telomere and Is Dynamic at Stable Telomeres

A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining

A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity.

A new method to efficiently induce a site‐specific double‐strand break in the fission yeast Schizosaccharomyces pombe ⬇️

A new model for vitamin K-dependent carboxylation: the catalytic base that deprotonates vitamin K hydroquinone is not Cys but an activated amine

A two-step model for senescence triggered by a single critically short telomere

Brønsted analysis reveals Lys218 as the carboxylase active site base that deprotonates vitamin K hydroquinone to initiate vitamin K-dependent protein carboxylation

Editorial: The Evolving Telomeres

Generation and analysis of a barcode-tagged insertion mutant library in the fission yeast Schizosaccharomyces pombe

Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities.

Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants.

Nonhomologous End-Joining with Minimal Sequence Loss Is Promoted by the Mre11-Rad50-Nbs1-Ctp1 Complex in Schizosaccharomyces pombe

Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres.

Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis ⬇️

Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis.

Saccharomyces cerevisiae linear chromosome stability (lcs) mutants increase the loss rate of artificial and natural linear chromosomes

Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan.

TEL2, an essential gene required for telomere length regulation and telomere position effect in Saccharomyces cerevisiae

Tel1p Preferentially Associates with Short Telomeres to Stimulate Their Elongation

Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

The C Terminus of the Major Yeast Telomere Binding Protein Rap1p Enhances Telomere Formation ⬇️

The ZDS1 and ZDS2 proteins require the Sir3p component of yeast silent chromatin to enhance the stability of short linear centromeric plasmids.

The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2)

The physiology of vitamin K nutriture and vitamin K-dependent protein function in atherosclerosis.

The vitamin K-dependent carboxylase has been acquired by Leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation

The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction.

The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA ⬇️

Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells.

Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

Yeast telomerase appears to frequently copy the entire template in vivo.

Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast

r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step.